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VIBES: A consensus subtyping of the vaginal microbiota reveals novel classification criteria

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Diego Fernández-Edreira | Jose Liñares-Blanco | Patricia V.-del-Río | Carlos Fernandez-Lozano

A shared mechanism for TNP-ATP recognition by members of the P2X receptor family

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Xiao-Bo Ma | Chen-Xi Yue | Yan Liu | Yang Yang | Jin Wang | Xiao-Na Yang | Li-Dong Huang | Michael X. Zhu | Motoyuki Hattori | Chang-Zhu Li | Ye Yu | Chang-Run Guo

Deep-HPI-pred: An R-Shiny applet for network-based classification and prediction of Host-Pathogen protein-protein interactions

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Muhammad Tahir ul Qamar | Fatima Noor | Yi-Xiong Guo | Xi-Tong Zhu | Ling-Ling Chen

Network-based identification and mechanism exploration of active ingredients against Alzheimer’s disease via targeting endoplasmic reticulum stress from traditional chinese medicine

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Zhao Dai | Tian Hu | Junwen Wei | Xue Wang | Chuipu Cai | Yong Gu | Yunhui Hu | Wenjia Wang | Qihui Wu | Jiansong Fang

Unsupervised machine learning for risk stratification and identification of relevant subgroups of ascending aorta dimensions using cardiac CT and clinical data

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Research funded by Ministero della Salute (RRC-2022-23680785)

Authors: Mario Zanfardino | Bruna Punzo | Erica Maffei | Luca Saba | Eduardo Bossone | Stefano Nistri | Ludovico La Grutta | Monica Franzese | Carlo Cavaliere | Filippo Cademartiri

Finding new cancer epigenetic and genetic biomarkers from cell-free DNA by combining SALP-seq and machine learning

JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal

Research funded by National Natural Science Foundation of China (61971122)

Authors: Shicai Liu | Jian Wu | Qiang Xia | Hongde Liu | Weiwei Li | Xinyi Xia | Jinke Wang

Genome mining of metabolic gene clusters in the Rubiaceae family

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Samara Mireza Correia de Lemos | Alexandre Rossi Paschoal | Romain Guyot | Marnix Medema | Douglas Silva Domingues

DeepFusion: A deep bimodal information fusion network for unraveling protein-RNA interactions using in vivo RNA structures

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Yixuan Qiao | Rui Yang | Yang Liu | Jiaxin Chen | Lianhe Zhao | Peipei Huo | Zhihao Wang | Dechao Bu | Yang Wu | Yi Zhao

Discovery of a novel marine Bacteroidetes with a rich repertoire of carbohydrate-active enzymes

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Beihan Chen | Guohua Liu | Quanrui Chen | Huanyu Wang | Le Liu | Kai Tang

Applying data mining techniques to medical time series: an empirical case study in electroencephalography and stabilometry

JOURNAL ARTICLE published 2016 in Computational and Structural Biotechnology Journal

Authors: A. Anguera | J.M. Barreiro | J.A. Lara | D. Lizcano

Curvature-enhanced graph convolutional network for biomolecular interaction prediction

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Research funded by China Scholarship Council (202006130147) | Government of Singapore Ministry of Education (MOE-T2EP20221-0003,MOE-T2EP20120-0013,MOE-T2EP20220-0010,RG16/23) | National Natural Science Foundation of China (62032007,61873089)

Authors: Cong Shen | Pingjian Ding | Junjie Wee | Jialin Bi | Jiawei Luo | Kelin Xia

Smad4 regulates TGF-β1-mediated hedgehog activation to promote epithelial-to-mesenchymal transition in pancreatic cancer cells by suppressing Gli1 activity

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Hangcheng Guo | Zujian Hu | Xuejia Yang | Ziwei Yuan | Mengsi Wang | Chaoyue Chen | Lili Xie | Yuanyuan Gao | Wangjian Li | Yongheng Bai | Chunjing Lin

A Structural Perspective on the Regulation of Human Single-Stranded DNA Binding Protein 1 (hSSB1, OBFC2B) Function in DNA Repair

JOURNAL ARTICLE published 2019 in Computational and Structural Biotechnology Journal

Authors: Teegan Lawson | Serene El-Kamand | Ruvini Kariawasam | Derek J. Richard | Liza Cubeddu | Roland Gamsjaeger

Experimental and computational approaches to unravel microbial community assembly

JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal

Authors: Daniel Aguirre de Cárcer

Phosphopeptide binding to the N-SH2 domain of tyrosine phosphatase SHP2 correlates with the unzipping of its central β-sheet

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Michelangelo Marasco | John Kirkpatrick | Teresa Carlomagno | Jochen S. Hub | Massimiliano Anselmi

Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Jie Li | Tian Yu | Juan Sun | Mingwei Ma | Zicheng Zheng | Weiming Kang | Xin Ye

Deep learning-based characterization of neutrophil activation phenotypes in ex vivo human Candida blood infections

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Research funded by Bundesministerium für Bildung und Forschung (13GW0456B) | German Research Foundation (210879364)

Authors: Arjun Sarkar | Jan-Philipp Praetorius | Marc Thilo Figge

NeuralBeds: Neural embeddings for efficient DNA data compression and optimized similarity search

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Research funded by Bundesministerium für Bildung und Forschung (031L0288A,031L0288C)

Authors: Oluwafemi A. Sarumi | Maximilian Hahn | Dominik Heider

Stabilization of the retromer complex: Analysis of novel binding sites of bis-1,3-phenyl guanylhydrazone 2a to the VPS29/VPS35 interface

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Elisa Fagnani | Francesco Bonì | Pierfausto Seneci | Davide Gornati | Luca Muzio | Eloise Mastrangelo | Mario Milani

Improving generalization capability of deep learning-based nuclei instance segmentation by non-deterministic train time and deterministic test time stain normalization

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Research funded by Österreichische Forschungsförderungsgesellschaft (872636)

Authors: Amirreza Mahbod | Georg Dorffner | Isabella Ellinger | Ramona Woitek | Sepideh Hatamikia