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Microglia promote remyelination independent of their role in clearing myelin debris

JOURNAL ARTICLE published December 2023 in Cell Reports

Authors: Charbel S. Baaklini | Madelene F.S. Ho | Tristan Lange | Brady P. Hammond | Sharmistha P. Panda | Martin Zirngibl | Sameera Zia | Kassandre Himmelsbach | Heli Rana | Braxton Phillips | Daria Antoszko | Jeremies Ibanga | Mizuki Lopez | Kelly V. Lee | Michael B. Keough | Andrew V. Caprariello | Bradley J. Kerr | Jason R. Plemel

De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function

JOURNAL ARTICLE published December 2023 in Cell Reports

Authors: Jie Wan | Cheng Cheng | Jiajia Hu | Haiyan Huang | Qiaoqiao Han | Zuliang Jie | Qiang Zou | Jian-Hong Shi | Xiaoyan Yu

Calmodulin regulates protease versus co-chaperone activity of a metacaspase

JOURNAL ARTICLE published November 2023 in Cell Reports

Authors: Anna Maria Eisele-Bürger | Frederik Eisele | Sandra Malmgren Hill | Xinxin Hao | Kara L. Schneider | Rahmi Imamoglu | David Balchin | Beidong Liu | F. Ulrich Hartl | Peter V. Bozhkov | Thomas Nyström

Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation

JOURNAL ARTICLE published November 2023 in Cell Reports

Research funded by Natural Science Foundation of Jiangsu Province (BK20200676) | National Natural Science Foundation of China (81972610,82002914,82072765)

Authors: Zehe Ge | Miao Xu | Yuqian Ge | Guang Huang | Dongyin Chen | Xiuquan Ye | Yibei Xiao | Hongyu Zhu | Rong Yin | Hua Shen | Gaoxiang Ma | Lianwen Qi | Guining Wei | Dongmei Li | Shaofeng Wei | Meng Zhu | Hongxia Ma | Zhumei Shi | Xiuxing Wang | Xin Ge | Xu Qian

NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance

JOURNAL ARTICLE published December 2023 in Cell Reports

Authors: Wenzhe Zhang | Rongrong Zhang | Ling Wu | Chendi Zhu | Chuanxin Zhang | Chengpeng Xu | Shidou Zhao | Xinchen Liu | Ting Guo | Yueshuang Lu | Zheng Gao | Xiao Yu | Lei Li | Zi-Jiang Chen | Yingying Qin | Xue Jiao

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression

JOURNAL ARTICLE published December 2023 in Cell Reports

Authors: Marie-Anne Goyette | Stéphanie Duhamel | Léo Aubert | Ariane Pelletier | Paul Savage | Marie-Pier Thibault | Radia Marie Johnson | Peter Carmeliet | Mark Basik | Louis Gaboury | William J. Muller | Morag Park | Philippe P. Roux | Jean-Philippe Gratton | Jean-François Côté

Deep ancestry of Bornean hunter-gatherers supports long-term local ancestry dynamics

JOURNAL ARTICLE published November 2023 in Cell Reports

Authors: Pradiptajati Kusuma | Murray P. Cox | Graeme Barker | Herawati Sudoyo | J. Stephen Lansing | Guy S. Jacobs

Topology recapitulates morphogenesis of neuronal dendrites

JOURNAL ARTICLE published November 2023 in Cell Reports

Research funded by National Science Foundation (GR117147) | National Institutes of Health (R01 NS118884) | Bundesministerium für Bildung und Forschung (031L0229)

Authors: Maijia Liao | Alex D. Bird | Hermann Cuntz | Jonathon Howard

De novo establishment of circuit modules restores locomotion after spinal cord injury in adult zebrafish

JOURNAL ARTICLE published October 2022 in Cell Reports

Authors: Chun-Xiao Huang | Zhen Wang | Jianwei Cheng | Zhiqiang Zhu | Na N. Guan | Jianren Song

The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus

JOURNAL ARTICLE published November 2023 in Cell Reports

Authors: Xiaoying Yu | Kathryn M. Hastie | Carl W. Davis | Ruben Diaz Avalos | Dewight Williams | Diptiben Parekh | Sean Hui | Colin Mann | Chitra Hariharan | Ayato Takada | Rafi Ahmed | Erica Ollmann Saphire

Chlorophyll biosynthesis under the control of arginine metabolism

JOURNAL ARTICLE published November 2023 in Cell Reports

Research funded by European Research Council (854126)

Authors: Éva Kiss | Jana Talbot | Nathan B.P. Adams | Stanislav Opekar | Martin Moos | Jan Pilný | Tatjana Kvasov | Emilia Schneider | Peter Koník | Petr Šimek | Roman Sobotka

Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity

JOURNAL ARTICLE published December 2023 in Cell Reports

Authors: Riccardo Guidi | Christopher Wedeles | Daqi Xu | Krzysztof Kolmus | Sarah E. Headland | Grace Teng | Joseph Guillory | Yi Jimmy Zeng | Tommy K. Cheung | Subhra Chaudhuri | Zora Modrusan | Yuxin Liang | Stuart Horswell | Benjamin Haley | Sascha Rutz | Christopher Rose | Yvonne Franke | Donald S. Kirkpatrick | Jason A. Hackney | Mark S. Wilson

Molecular annotation of G protein variants in a neurological disorder

JOURNAL ARTICLE published December 2023 in Cell Reports

Authors: Kevin M. Knight | Elizabeth G. Obarow | Wenyuan Wei | Sepehr Mani | Maria I. Esteller | Meng Cui | Ning Ma | Sarah A. Martin | Emily Brinson | Natalie Hewitt | Gaby M. Soden | Diomedes E. Logothetis | Nagarajan Vaidehi | Henrik G. Dohlman

Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in Zebrafish

JOURNAL ARTICLE published August 2016 in Cell Reports

Authors: Zhenkang Chen | Yangbo Hu | Bridgette M. Cumming | Pei Lu | Lipeng Feng | Jiaoyu Deng | Adrie J.C. Steyn | Shiyun Chen

CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection

JOURNAL ARTICLE published March 2016 in Cell Reports

Authors: Changying Jiang | Zhicheng Zhou | Yanping Quan | Shilei Zhang | Tingting Wang | Xueqiang Zhao | Clayton Morrison | Mark T. Heise | Wenqian He | Matthew S. Miller | Xin Lin

Mdm2 Phosphorylation Regulates Its Stability and Has Contrasting Effects on Oncogene and Radiation-Induced Tumorigenesis

JOURNAL ARTICLE published September 2016 in Cell Reports

Authors: Michael I. Carr | Justine E. Roderick | Hugh S. Gannon | Michelle A. Kelliher | Stephen N. Jones

Cadherin-7 Regulates Mossy Fiber Connectivity in the Cerebellum

JOURNAL ARTICLE published October 2014 in Cell Reports

Authors: Ken-ichiro Kuwako | Yoshinori Nishimoto | Satoshi Kawase | Hirotaka James Okano | Hideyuki Okano

Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking

JOURNAL ARTICLE published November 2016 in Cell Reports

Research funded by NIH Program (P01CA171983) | NIH Shared Instrumentation (S10OD010756-01A1) | NIH-NCI Cancer Center Support (P30 CA016059) | NIH Shared Instrumentation (S10RR031535)

Authors: Megan M. Young | Yoshinori Takahashi | Todd E. Fox | Jong K. Yun | Mark Kester | Hong-Gang Wang

Distinct Transcriptional Programs Control Cross-Priming in Classical and Monocyte-Derived Dendritic Cells

JOURNAL ARTICLE published June 2016 in Cell Reports

Authors: Carlos G. Briseño | Malay Haldar | Nicole M. Kretzer | Xiaodi Wu | Derek J. Theisen | Wumesh KC | Vivek Durai | Gary E. Grajales-Reyes | Arifumi Iwata | Prachi Bagadia | Theresa L. Murphy | Kenneth M. Murphy

EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release

JOURNAL ARTICLE published December 2022 in Cell Reports

Authors: Kaustav Mukherjee | James J. Bieker