Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells

JOURNAL ARTICLE published 5 July 2019 in Science Advances

Research funded by National Institutes of Health (R33CA174562) | National Institutes of Health (R44CA180482) | National Institutes of Health (R01CA218356) | National Institutes of Health (U01CA198900) | National Institutes of Health (R21CA235340) | China Scholarship Council (201706010064)

Authors: Jiantong Dong | Yu Jen Jan | Ju Cheng | Ryan Y. Zhang | Meng Meng | Matthew Smalley | Pin-Jung Chen | Xinghong Tang | Patrick Tseng | Lirong Bao | Tzu-Yang Huang | Dongjing Zhou | Yupin Liu | Xiaoshu Chai | Haibo Zhang | Anqi Zhou | Vatche G. Agopian | Edwin M. Posadas | Jing-Jong Shyue | Steven J. Jonas | Paul S. Weiss | Mengyuan Li | Guangjuan Zheng | Hsiao-hua Yu | Meiping Zhao | Hsian-Rong Tseng | Yazhen Zhu

Sequential deconstruction of composite drug transport in metastatic breast cancer

JOURNAL ARTICLE published 26 June 2020 in Science Advances

Research funded by National Science Foundation (DMS-1716737) | National Science Foundation (DMS-1930583) | National Institutes of Health (U54CA210181) | National Institutes of Health (R01CA193880) | National Institutes of Health (R01CA222959) | National Institutes of Health (U01CA196403) | National Institutes of Health (U01CA213759) | National Institutes of Health (R01CA226537) | National Institutes of Health (R01CA222007) | U.S. Department of Defense (W81XWH-17-1-0389)

Authors: Shreya Goel | Guodong Zhang | Prashant Dogra | Sara Nizzero | Vittorio Cristini | Zhihui Wang | Zhenhua Hu | Zheng Li | Xuewu Liu | Haifa Shen | Mauro Ferrari

The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra

JOURNAL ARTICLE published 23 December 2022 in Science Advances

Authors: Matthias Christian Vogg | Jaroslav Ferenc | Wanda Christa Buzgariu | Chrystelle Perruchoud | Paul Gerald Layague Sanchez | Leonardo Beccari | Clara Nuninger | Youn Le Cras | Céline Delucinge-Vivier | Panagiotis Papasaikas | Stéphane Vincent | Brigitte Galliot | Charisios D. Tsiairis

Evolutionary metabolomics of specialized metabolism diversification in the genus Nicotiana highlights N- acylnornicotine innovations

JOURNAL ARTICLE published 25 August 2023 in Science Advances

Authors: David Elser | David Pflieger | Claire Villette | Baptiste Moegle | Laurence Miesch | Emmanuel Gaquerel

Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation

JOURNAL ARTICLE published 9 February 2024 in Science Advances

Authors: Jaakko Mattila | Arto Viitanen | Gaia Fabris | Tetiana Strutynska | Jerome Korzelius | Ville Hietakangas

Disproportionation chemistry in K ₂ PtCl ₄ visualized at atomic resolution using scanning transmission electron microscopy

JOURNAL ARTICLE published 9 February 2024 in Science Advances

Authors: Jacob G. Smith | Kaustubh J. Sawant | Zhenhua Zeng | Tim B. Eldred | Jianbo Wu | Jeffrey P. Greeley | Wenpei Gao

Pri peptides temporally coordinate transcriptional programs during epidermal differentiation

JOURNAL ARTICLE published 9 February 2024 in Science Advances

Authors: Maylis Gallois | Delphine Menoret | Simon Marques-Prieto | Audrey Montigny | Philippe Valenti | Bernard Moussian | Serge Plaza | François Payre | Hélène Chanut-Delalande

3D-printed automation for optimized PET radiochemistry

JOURNAL ARTICLE published 6 September 2019 in Science Advances

Research funded by National Center for Advancing Translational Sciences (5 UL1 TR000457-07)

Authors: Alejandro Amor-Coarasa | James M. Kelly | John W. Babich

Orientation pinwheels in primary visual cortex of a highly visual marsupial

JOURNAL ARTICLE published 30 September 2022 in Science Advances

Authors: Young Jun Jung | Ali Almasi | Shi H. Sun | Molis Yunzab | Shaun L. Cloherty | Sebastien H. Bauquier | Marilyn Renfree | Hamish Meffin | Michael R. Ibbotson

Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs

JOURNAL ARTICLE published 9 February 2024 in Science Advances

Authors: James Jiqi Wang | Sanshan Jin | Heng Zhang | Youwei Xu | Wen Hu | Yi Jiang | Chen Chen | Dao Wen Wang | H. Eric Xu | Canrong Wu

Cx26 heterozygous mutations cause hyperacusis-like hearing oversensitivity and increase susceptibility to noise

JOURNAL ARTICLE published 10 February 2023 in Science Advances

Authors: Li-Man Liu | Chun Liang | Jin Chen | Shu Fang | Hong-Bo Zhao

A positive, growth-based PAM screen identifies noncanonical motifs recognized by the S. pyogenes Cas9

JOURNAL ARTICLE published 17 July 2020 in Science Advances

Research funded by National Science Foundation (MCB-1452902) | National Institutes of Health (1R35GM119561) | National Institutes of Health (9R15HL147265) | Camille and Henry Dreyfus Foundation (T7-17-038) | Agilent Technologies (Gift #3926)

Authors: D. Collias | R. T. Leenay | R. A. Slotkowski | Z. Zuo | S. P. Collins | B. A. McGirr | J. Liu | C. L. Beisel

Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake

JOURNAL ARTICLE published 16 July 2021 in Science Advances

Research funded by National Natural Science Foundation of China (91954118) | National Natural Science Foundation of China (31861143048) | National Natural Science Foundation of China (31670745) | National Natural Science Foundation of China (31670746) | National Basic Research Program of China (2017YFA0504600) | National Basic Research Program of China (2016YFA0501101)

Authors: Miaoqing Hu | Fan Yang | Yawen Huang | Xin You | Desheng Liu | Shan Sun | Sen-Fang Sui

Excessive local host-graft connectivity in aging and amyloid-loaded brain

JOURNAL ARTICLE published 10 June 2022 in Science Advances

Authors: Judith Thomas | Maria Fernanda Martinez-Reza | Manja Thorwirth | Yvette Zarb | Karl-Klaus Conzelmann | Stefanie M. Hauck | Sofia Grade | Magdalena Götz

Evidence for enormous iodide anion migration in lanthanum oxyiodide–based solid

JOURNAL ARTICLE published 22 October 2021 in Science Advances

Authors: Nobuhito Imanaka | Muhammad Radzi Iqbal Bin Misran | Naoyoshi Nunotani

Erratum for the Research Resource: “Deep brain stimulation of the subgenual cingulum and uncinate fasciculus for the treatment of posttraumatic stress disorder” by Hamani et al .

JOURNAL ARTICLE published 16 February 2024 in Science Advances

Mechanistic insight into glioma through spatially multidimensional proteomics

JOURNAL ARTICLE published 16 February 2024 in Science Advances

Authors: Lei Shen | Zhourui Zhang | Pengfei Wu | Jingyi Yang | Yuankun Cai | Keyu Chen | Songshan Chai | Jingwei Zhao | Hongyu Chen | Xuan Dai | Bangkun Yang | Wei Wei | Lixin Dong | Jincao Chen | Pucha Jiang | Changjun Cao | Chao Ma | Chengshi Xu | Yichun Zou | Jibo Zhang | Wenping Xiong | Zhengwei Li | Shuangxiang Xu | Bing Shu | Mengyang Wang | Zejin Li | Qiongqiong Wan | Nanxiang Xiong | Suming Chen

Aberration-corrected STEM imaging of 2D materials: Artifacts and practical applications of threefold astigmatism

JOURNAL ARTICLE published 11 September 2020 in Science Advances

Authors: Sergei Lopatin | Areej Aljarb | Vladimir Roddatis | Tobias Meyer | Yi Wan | Jui-Han Fu | Mohamed Hedhili | Yimo Han | Lain-Jong Li | Vincent Tung

Human organ rejuvenation by VEGF-A: Lessons from the skin

JOURNAL ARTICLE published 24 June 2022 in Science Advances

Authors: Aviad Keren | Marta Bertolini | Yaniv Keren | Yehuda Ullmann | Ralf Paus | Amos Gilhar

Diamond-based microwave quantum amplifier

JOURNAL ARTICLE published 9 December 2022 in Science Advances

Authors: Alexander Sherman | Oleg Zgadzai | Boaz Koren | Idan Peretz | Eyal Laster | Aharon Blank