Competition between PAF1 and MLL1/COMPASS confers the opposing function of LEDGF/p75 in HIV latency and proviral reactivation

JOURNAL ARTICLE published 15 May 2020 in Science Advances

Research funded by National Natural Science Foundation of China (31872825) | State Key Laboratory of Experimental Hematology (157-Zk19-03) | Tianjin Natural Science Foundation (18JCYBJC42400) | CAMS Initiative for Innovative Medicine (2018-I2M-AI-010)

Authors: Ru Gao | Jiaqian Bao | Han Yan | Liya Xie | Wanchang Qin | Hanhan Ning | Shuqi Huang | Jun Cheng | Renyong Zhi | Zexing Li | Bronwyn Tucker | Yupeng Chen | Kai Zhang | Xudong Wu | Zhe Liu | Xin Gao | Deqing Hu

Perturbation of the deep-Earth carbon cycle in response to the Cambrian Explosion

JOURNAL ARTICLE published 4 March 2022 in Science Advances

Authors: Andrea Giuliani | Russell N. Drysdale | Jon D. Woodhead | Noah J. Planavsky | David Phillips | Janet Hergt | William L. Griffin | Senan Oesch | Hayden Dalton | Gareth R. Davies

Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells

JOURNAL ARTICLE published 31 July 2020 in Science Advances

Research funded by National Institutes of Health (1RO1CA142805) | National Research Foundation of Korea (NRF-2017R1C1B1006072)

Authors: Seung Ho Shin | Ji Su Lee | Jia-Min Zhang | Sungbin Choi | Zarko V. Boskovic | Ran Zhao | Mengqiu Song | Rui Wang | Jie Tian | Mee-Hyun Lee | Jae Hwan Kim | Minju Jeong | Jung Hyun Lee | Michael Petukhov | Sam W. Lee | Sang Gyun Kim | Lee Zou | Sanguine Byun

Evolutionary epigenomic analyses in mammalian early embryos reveal species-specific innovations and conserved principles of imprinting

JOURNAL ARTICLE published 26 November 2021 in Science Advances

Authors: Xukun Lu | Yu Zhang | Lijuan Wang | Leyun Wang | Huili Wang | Qianhua Xu | Yunlong Xiang | Chaolei Chen | Feng Kong | Weikun Xia | Zili Lin | Sinan Ma | Ling Liu | Xiangguo Wang | Hemin Ni | Wei Li | Yong Guo | Wei Xie

Solid Earth–atmosphere interaction forces during the 15 January 2022 Tonga eruption

JOURNAL ARTICLE published 13 January 2023 in Science Advances

Authors: Ricardo Garza-Girón | Thorne Lay | Frederick Pollitz | Hiroo Kanamori | Luis Rivera

Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart

JOURNAL ARTICLE published 15 October 2021 in Science Advances

Authors: Melissa Valussi | Johannes Besser | Katharina Wystub-Lis | Sven Zukunft | Manfred Richter | Thomas Kubin | Thomas Boettger | Thomas Braun

Disproportionation chemistry in K ₂ PtCl ₄ visualized at atomic resolution using scanning transmission electron microscopy

JOURNAL ARTICLE published 9 February 2024 in Science Advances

Authors: Jacob G. Smith | Kaustubh J. Sawant | Zhenhua Zeng | Tim B. Eldred | Jianbo Wu | Jeffrey P. Greeley | Wenpei Gao

Pri peptides temporally coordinate transcriptional programs during epidermal differentiation

JOURNAL ARTICLE published 9 February 2024 in Science Advances

Authors: Maylis Gallois | Delphine Menoret | Simon Marques-Prieto | Audrey Montigny | Philippe Valenti | Bernard Moussian | Serge Plaza | François Payre | Hélène Chanut-Delalande

Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs

JOURNAL ARTICLE published 9 February 2024 in Science Advances

Authors: James Jiqi Wang | Sanshan Jin | Heng Zhang | Youwei Xu | Wen Hu | Yi Jiang | Chen Chen | Dao Wen Wang | H. Eric Xu | Canrong Wu

Stem cell mTOR signaling directs region-specific cell fate decisions during intestinal nutrient adaptation

JOURNAL ARTICLE published 9 February 2024 in Science Advances

Authors: Jaakko Mattila | Arto Viitanen | Gaia Fabris | Tetiana Strutynska | Jerome Korzelius | Ville Hietakangas

CATER: Combined Animal Tracking & Environment Reconstruction

JOURNAL ARTICLE published 21 April 2023 in Science Advances

Authors: Lars Haalck | Michael Mangan | Antoine Wystrach | Leo Clement | Barbara Webb | Benjamin Risse

Submilligram-scale separation of near-zigzag single-chirality carbon nanotubes by temperature controlling a binary surfactant system

JOURNAL ARTICLE published 19 February 2021 in Science Advances

Research funded by National Natural Science Foundation of China (51820105002, 11634014, 51872320) | National Key Research and Development Program of China Stem Cell and Translational Research (2020YFA0714700 and 2018YFA0208402) | Youth Innovation Promotion Association of CAS (2020005) | Strategic Priority Research Program of Chinese Academy of Sciences (XDB33030100) | Key Research Program of Frontier Sciences, CAS (QYZDBSSW-SYS028)

Authors: Dehua Yang | Linhai Li | Xiaojun Wei | Yanchun Wang | Weiya Zhou | Hiromichi Kataura | Sishen Xie | Huaping Liu

Atypical Legionella GTPase effector hijacks host vesicular transport factor p115 to regulate host lipid droplet

JOURNAL ARTICLE published 16 December 2022 in Science Advances

Authors: Tao-Tao Chen | Yanling Lin | Shijun Zhang | Shuxin Liu | Lei Song | Wenhong Zhong | Zhao-Qing Luo | Aidong Han

Myeloid-derived growth factor inhibits inflammation and alleviates endothelial injury and atherosclerosis in mice

JOURNAL ARTICLE published 21 May 2021 in Science Advances

Research funded by National Natural Science Foundation of China (81870573, 81370896, 81570730) | National Natural Science Foundation of China (NSFC 81870573) | National Natural Science Foundation of China (81370896) | National Natural Science Foundation of China (81570730) | National Natural Science Foundation of China (2016YFC1305601) | National Natural Science Foundation of China (WJ2017H0031) | National Key Research and Development Program of China Stem Cell and Translational Research (2016YFC1305601) | Research Project of Health Commission of Hubei Province (WJ2017H0031) | Hubei Province’s Outstanding Medical Academic Leader Program (2014-9)

Authors: Biying Meng | Yixiang Li | Yan Ding | Xiaoli Xu | Li Wang | Bei Guo | Biao Zhu | Jiajia Zhang | Lin Xiang | Jing Dong | Min Liu | Lingwei Xiang | Guangda Xiang

Localized immune surveillance of primary melanoma in the skin deciphered through executable modeling

JOURNAL ARTICLE published 14 April 2023 in Science Advances

Authors: Rowan Howell | James Davies | Matthew A. Clarke | Anna Appios | Inês Mesquita | Yashoda Jayal | Ben Ringham-Terry | Isabel Boned Del Rio | Jasmin Fisher | Clare L. Bennett

Heart neurons use clock genes to control myocyte proliferation

JOURNAL ARTICLE published 3 December 2021 in Science Advances

Authors: Emmanouil Tampakakis | Harshi Gangrade | Stephanie Glavaris | Myo Htet | Sean Murphy | Brian Leei Lin | Ting Liu | Amir Saberi | Matthew Miyamoto | William Kowalski | Yoh-Suke Mukouyama | Gabsang Lee | Liliana Minichiello | Chulan Kwon

Brain-wide neural dynamics of poststroke recovery induced by optogenetic stimulation

JOURNAL ARTICLE published 13 August 2021 in Science Advances

Research funded by National Institute of Mental Health (RF1MH11422701) | National Institute of Neurological Disorders and Stroke (R01NS093057)

Authors: Shahabeddin Vahdat | Arjun Vivek Pendharkar | Terrance Chiang | Sean Harvey | Haruto Uchino | Zhijuan Cao | Anika Kim | ManKin Choy | Hansen Chen | Hyun Joo Lee | Michelle Y. Cheng | Jin Hyung Lee | Gary K. Steinberg

Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmission

JOURNAL ARTICLE published 6 September 2019 in Science Advances

Research funded by National Institutes of Health (R01MH101221) | Howard Hughes Medical Institute (N/A) | National Eye Institute (Intramural funds) | National Natural Science Foundation of China (31671114, 81871079) | National Natural Science Foundation of China (81730036, 81525007) | National Natural Science Foundation of China-Yunnan Joint Fund (81671122) | Key R&D program of Hunan Province (2018DK2016) | Science and technology projects of Hunan Province (2016RS2001, 2016JC2055) | Simons Foundation Autism Research Initiative (SFARI 303241)

Authors: Hui Guo | Ying Li | Lu Shen | Tianyun Wang | Xiangbin Jia | Lijuan Liu | Tao Xu | Mengzhu Ou | Kendra Hoekzema | Huidan Wu | Madelyn A. Gillentine | Cenying Liu | Hailun Ni | Pengwei Peng | Rongjuan Zhao | Yu Zhang | Chanika Phornphutkul | Alexander P. A. Stegmann | Carlos E. Prada | Robert J. Hopkin | Joseph T. Shieh | Kirsty McWalter | Kristin G. Monaghan | Peter M. van Hasselt | Koen van Gassen | Ting Bai | Min Long | Lin Han | Yingting Quan | Meilin Chen | Yaowen Zhang | Kuokuo Li | Qiumeng Zhang | Jieqiong Tan | Tengfei Zhu | Yaning Liu | Nan Pang | Jing Peng | Daryl A. Scott | Seema R. Lalani | Mahshid Azamian | Grazia M. S. Mancini | Darius J. Adams | Malin Kvarnung | Anna Lindstrand | Ann Nordgren | Jonathan Pevsner | Ikeoluwa A. Osei-Owusu | Corrado Romano | Giuseppe Calabrese | Ornella Galesi | Jozef Gecz | Eric Haan | Judith Ranells | Melissa Racobaldo | Magnus Nordenskjold | Suneeta Madan-Khetarpal | Jessica Sebastian | Susie Ball | Xiaobing Zou | Jingping Zhao | Zhengmao Hu | Fan Xia | Pengfei Liu | Jill A. Rosenfeld | Bert B. A. de Vries | Raphael A. Bernier | Zhi-Qing David Xu | Honghui Li | Wei Xie | Robert B. Hufnagel | Evan E. Eichler | Kun Xia

Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth

JOURNAL ARTICLE published 4 December 2020 in Science Advances

Authors: Noboru J. Sakabe | Ivy Aneas | Nicholas Knoblauch | Debora R. Sobreira | Nicole Clark | Cristina Paz | Cynthia Horth | Ryan Ziffra | Harjot Kaur | Xiao Liu | Rebecca Anderson | Jean Morrison | Virginia C. Cheung | Chad Grotegut | Timothy E. Reddy | Bo Jacobsson | Mikko Hallman | Kari Teramo | Amy Murtha | John Kessler | William Grobman | Ge Zhang | Louis J. Muglia | Sarosh Rana | Vincent J. Lynch | Gregory E. Crawford | Carole Ober | Xin He | Marcelo A. Nóbrega

Storage and analysis of light-matter entanglement in a fiber-integrated system

JOURNAL ARTICLE published 8 July 2022 in Science Advances

Authors: Jelena V. Rakonjac | Giacomo Corrielli | Dario Lago-Rivera | Alessandro Seri | Margherita Mazzera | Samuele Grandi | Roberto Osellame | Hugues de Riedmatten