The future of chemical probes is diversity

JOURNAL ARTICLE published 2022 in RSC Medicinal Chemistry

Authors: Susanne Müller | Stephen Frye | Jonathan Baell

Expanding the structure–activity relationships of alkynyl diphenylurea scaffold as promising antibacterial agents

JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Research funded by Science and Technology Development Fund (43883)

Authors: Hanzada T. Nour El-Din | Mohamed M. Elsebaie | Nader S. Abutaleb | Ahmed M. Kotb | Ahmed S. Attia | Mohamed N. Seleem | Abdelrahman S. Mayhoub

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JOURNAL ARTICLE published 2022 in RSC Medicinal Chemistry

Synthesis and structure–activity relationship (SAR) studies of 1,2,3-triazole, amide, and ester-based benzothiazole derivatives as potential molecular probes for tau protein

JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Research funded by Kementerian Riset dan Teknologi/Badan Riset dan Inovasi Nasional (8245-ID)

Authors: Hendris Wongso | Maiko Ono | Tomoteru Yamasaki | Katsushi Kumata | Makoto Higuchi | Ming-Rong Zhang | Michael J. Fulham | Andrew Katsifis | Paul A. Keller

Proline pre-conditioning of cell monolayers increases post-thaw recovery and viability by distinct mechanisms to other osmolytes

JOURNAL ARTICLE published 2021 in RSC Medicinal Chemistry

Research funded by Wellcome Trust (105627/Z/14/Z) | H2020 European Research Council (638661,789182)

Authors: Trisha L. Bailey | Juan Ramon Hernandez-Fernaud | Matthew I. Gibson

De novo molecular drug design benchmarking

JOURNAL ARTICLE published 2021 in RSC Medicinal Chemistry

Research funded by Natural Sciences and Engineering Research Council of Canada (510963,RGPIN-2017-05813)

Authors: Lauren L. Grant | Clarissa S. Sit

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JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Screening and optimization of phage display cyclic peptides against the WDR5 WBM site

JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Research funded by National Natural Science Foundation of China (82173658,82373720)

Authors: Lingyu Song | Jiawen Cao | Lin Chen | Zhiyan Du | Naixia Zhang | Danyan Cao | Bing Xiong

Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEAD·YAP1 interaction

JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Research funded by U.S. Department of Veterans Affairs (I01BX005188) | National Institutes of Health (R01CA264471) | American Cancer Society (RSG-12-092-01-CDD)

Authors: Khuchtumur Bum-Erdene | Mona K. Ghozayel | Mark J. Zhang | Giovanni Gonzalez-Gutierrez | Samy O. Meroueh

Mitochondria-targeted biotin-conjugated BODIPYs for cancer imaging and therapy

JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Research funded by Department of Biotechnology, Ministry of Science and Technology, India (BT/PR28133/NER/95/1383/2018) | Department of Science and Technology, Ministry of Science and Technology, India (IF160502) | Indian Council of Medical Research (2021-11018-F1)

Authors: Dhiraj Dutta | Rajshree R. Nair | Kashmiri Neog | S. Asha Nair | Pranjal Gogoi

Recent advances of phenotypic screening strategies in the application of anti-influenza virus drug discovery

JOURNAL ARTICLE published 2024 in RSC Medicinal Chemistry

Research funded by China Postdoctoral Science Foundation (2022M711938) | Natural Science Foundation of Jiangsu Province (SBK2023041680) | National Natural Science Foundation of China (82173677,82211530493) | Ministry of Health and Welfare (HI22C2067)

Authors: Huinan Jia | Lide Hu | Jiwei Zhang | Xing Huang | Yuanmin Jiang | Guanyu Dong | Chuanfeng Liu | Xinyong Liu | Meehyein Kim | Peng Zhan

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JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

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JOURNAL ARTICLE published 2020 in RSC Medicinal Chemistry

Peptide-based topical agents and intravenous hemostat for rapid hemostasis

JOURNAL ARTICLE published 2020 in RSC Medicinal Chemistry

Research funded by Department of Biotechnology , Ministry of Science and Technology (BT/PR27059/NNT/28/1543/2017)

Authors: Snehasish Ghosh | Archana Tripathi | Paramita Gayen | Rituparna Sinha Roy

In vitroandin vivosigma 1 receptor imaging studies in different disease states

JOURNAL ARTICLE published 2021 in RSC Medicinal Chemistry

Research funded by U.S. Department of Defense (PR161310)

Authors: Hebaalla Agha | Christopher R. McCurdy

Correction: Leishmania infantum isolates exhibit high infectivity and reduced susceptibility to amphotericin B

JOURNAL ARTICLE published 2020 in RSC Medicinal Chemistry

Authors: Paula Faral-Tello | Gonzalo Greif | Dinora Satragno | Yester Basmadjián | Carlos Robello

Discovery of benzoxazole–thiazolidinone hybrids as promising antibacterial agents against Staphylococcus aureus and Enterococcus species

JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Authors: Vijay Sai Krishna Cheerala | Abdul Akhir | Deepanshi Saxena | Rahul Maitra | Sidharth Chopra | Sundaresan Chittor Neelakantan

Dual FLT3/haspin kinase inhibitor based on 3H-pyrazolo[4,3-f]quinoline scaffold with activities against acute myeloid leukemia

JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Research funded by Foundation for the National Institutes of Health (1R01CA267978-01)

Authors: Allison L. Kempen | Nickolas R. Brauer | Herman O. Sintim

Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity

JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry

Research funded by Ministero dell’Istruzione, dell’Università e della Ricerca (201744BN5)

Authors: Laura De Luca | Lisa Lombardo | Salvatore Mirabile | Agostino Marrazzo | Maria Dichiara | Giuseppe Cosentino | Emanuele Amata | Rosaria Gitto

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JOURNAL ARTICLE published 2023 in RSC Medicinal Chemistry