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Pre-clinical development of chimeric antigen receptor T-cell immunotherapy: Implications of design for efficacy and safety

Journal Article published Jun 2018 in Best Practice & Research Clinical Haematology volume 31 issue 2 on pages 117 to 125

Research funded by Medical Research Council Canada (C11499/A21623) | British Lung Foundation | National Institute for Health Research (IS-BRC-1215-20006)

Authors: Leena Halim, Adam Ajina, John Maher

Phase III study of watchful waiting vs. rituximab as first-line treatment in advanced stage follicular lymphoma with low tumour burden (JCOG1411, FLORA study)

Journal Article published 13 Jun 2018 in Japanese Journal of Clinical Oncology

Research funded by National Cancer Center Research and Development Fund (TIN2012-32180) | Japan Agency for Medical Research and Development (TIN2012-32180)

Authors: Kenichi Miyamoto, Noriko Fukuhara, Dai Maruyama, Taro Shibata, Kenichi Nakamura, Kenichi Ishizawa, Kunihiro Tsukasaki, Hirokazu Nagai, Lymphoma Study Group of the Japan Clinical Oncology Group

New developments in systemic therapy for advanced biliary tract cancer

Journal Article published 11 Jun 2018 in Japanese Journal of Clinical Oncology

Research funded by National Cancer Center Research and Development Fund (29-A-3)

Authors: Chigusa Morizane, Makoto Ueno, Masafumi Ikeda, Takuji Okusaka, Hiroshi Ishii, Junji Furuse

The Story of Imatinib in GIST - a Journey through the Development of a Targeted Therapy

Journal Article published 2018 in Oncology Research and Treatment

Authors: Peter Reichardt

Specificity Protein Transcription Factors and Cancer: Opportunities for Drug Development

Journal Article published 15 Mar 2018 in Cancer Prevention Research

Authors: Stephen Safe, James Abbruzzese, Maen Abdelrahim, Erik Hedrick

Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor GrowthIn Vivo

Journal Article published 3 May 2018 in Clinical Cancer Research

Research funded by Boehringer Ingelheim RCV GmbH (MUV20121123, MUV20121123) | Vienna Fund for Innovative Interdisciplinary cancer Research | Hungarian Academy of Sciences | Herzfelder'sche Familienstiftung | Initiative for Cancer Research of the Medical University of Vienna | Oesterreichische Nationalbank (16912) | Hungarian National Research, Development and Innovation Office (AIK 12-1-2013-0041, K109626, K108465, KNN121510 and SNN114490, K116295, 16-1-2017-0439) | Semmelweis University Start-Up grant (40148-11658) | Ausztrian Science Foundation (I2872)

Authors: Viktoria Laszlo, Zsuzsanna Valko, Ildiko Kovacs, Judit Ozsvar, Mir Alireza Hoda, Thomas Klikovits, Dora Lakatos, Andras Czirok, Tamas Garay, Alexander Stiglbauer, Thomas H. Helbich, Marion Gröger, Jozsef Tovari, Walter Klepetko, Christine Pirker, Michael Grusch, Walter Berger, Frank Hilberg, Balazs Hegedus, Balazs Dome

Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties

Journal Article published 14 Jun 2018 in Journal of Hematology & Oncology volume 11 issue 1

Research funded by CAMS Innovation Fund for Medical Sciences (2017-I2M-3-007) | The National Key Research and Development Program of China (2016YFA0101000, 2016YFA0101003) | Beijing Key Laboratory of New Drug Development and Clinical Trial of Stem Cell Therapy (BZ0381) | National Natural Science Foundation of China (81473450)

Authors: Shihua Wang, Meiqian Xu, Xiaoxia Li, Xiaodong Su, Xian Xiao, Armand Keating, Robert Chunhua Zhao

Addition of histone deacetylase inhibitors does not improved prognosis in patients with myelodysplastic syndrome and acute myeloid leukemia compared with hypomethylating agents alone: A systematic review and meta-analysis of seven prospective cohort studies

Journal Article published Jun 2018 in Leukemia Research

Research funded by National Natural Science Foundation of China (81620108001, 81370373, 91439112, 91739302, 81270591, 81670132) | Jiangsu Province of China (BK20131167, RC2011105) | Jiangsu Provincial Special Program of Social Development (SBE2016740635) | Jiangsu Provincial Special Program of Medical Science (BL2012005) | Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)

Authors: Tingting Pan, Jiaqian Qi, Tao You, Liping Yang, Depei Wu, Yue Han, Li Zhu

The TGFβ-induced lncRNA TBILA promotes non-small cell lung cancer progression in vitro and in vivo via cis-regulating HGAL and activating S100A7/JAB1 signaling

Journal Article published Sep 2018 in Cancer Letters volume 432 on pages 156 to 168

Research funded by National Key Research Development Plan (2016YFC0905400) | National Key Basic Research Development Plan (2014CB542006) | CAMS Innovation Fund for Medical Sciences (2016-I2M-1-001, 2017-I2M-1-005) | Beijing Municipal Science and Technology Commission (Z151100004015188)

Authors: Zhiliang Lu, Yuan Li, Yun Che, Jianbing Huang, Shouguo Sun, Shuangshuang Mao, Yuanyuan Lei, Ning Li, Nan Sun, Jie He

The Intestinal Microbiota in Colorectal Cancer

Journal Article published Jun 2018 in Cancer Cell volume 33 issue 6 on pages 954 to 964

Research funded by BMVIT | Bundesministerium für Wissenschaft, Forschung und Wirtschaft | Wirtschaftsagentur Wien | Standortagentur Tirol | Austrian Science Fund (P 29379-B28) | Austrian Society of Gastroenterology and Hepatology | Christian Doppler Forschungsgesellschaft | Austrian Federal Ministry of Science, Research and Economy | National Foundation for Research, Technology and Development

Authors: Herbert Tilg, Timon E. Adolph, Romana R. Gerner, Alexander R. Moschen