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New phloroglucinol derivatives from Indonesian Baeckea frutescens

Journal Article published Feb 2017 in Tetrahedron volume 73 issue 8 on pages 1177 to 1181

Research funded by Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan | Japan Society for the Promotion of Science | Asia-Africa Science Platforms | Kobayashi International Scholarship Foundation (WCU-KLN-2016)

Authors: Takuya Ito, Khoirun Nisa, Senda Kartika Rakainsa, Sbehan Lallo, Hiroyuki Morita

Microwave-assisted synthesis of phenanthroimidazole derivatives as stabilizer of c-myc G-quadruplex DNA

Journal Article published Nov 2014 in Bioorganic & Medicinal Chemistry volume 22 issue 22 on pages 6503 to 6508

Research funded by Natural Science Foundation of Guangdong Province (S2011040000131) | Name of the Science and Technology Foundation of Guangdong Province (20070327029) | Guangdong Province Science and Technology Plan (20771044) | Guangzhou City Science and Technology Plan (2011J5200017) | Medical Science and Technology Research Foundation of Guangdong Province (WSTJJ20101231) | Foundation of Guangzhou Medical University (2010C15) | The Joint Natural Sciences Fund of The Department of Science and Technology | The First Affiliated Hospital of Guangdong Pharmaceutical University (GYFYLH201309)

Authors: Siyan Liao, Zhao Zhang, Qiong Wu, Xicheng Wang, Wenjie Mei

Oroxylin A sensitizes non-small cell lung cancer cells to anoikis via glucose-deprivation-like mechanisms: c-Src and hexokinase II

Journal Article published Jun 2013 in Biochimica et Biophysica Acta (BBA) - General Subjects volume 1830 issue 6 on pages 3835 to 3845

Research funded by National Science & Technology Major Project (2012ZX09103101-050, 2012ZX09103101-050) | International Cooperation Program of China (2008DFA32120) | National Natural Science Foundation of China (30973556, 81001452, 91029744, 81173086) | Natural Science Foundation of Jiangsu Province, China (BK2010432) | Science and Technology Development Program | Science and Technology, Jiangsu (BE2009674) | Graduate Innovation Fund of Simcere Pharmaceutical Group, China (CX11B-006XS) | Doctoral Talents Cultivation Plan of China Pharmaceutical University, China (2011 II BPY07) | Program for New Century Excellent Talents in University (NCET-12-0973)

Authors: Libin Wei, Qinsheng Dai, Yuxin Zhou, Meijuan Zou, Zhiyu Li, Na Lu, Qinglong Guo

Evaluation of phenylcyclopropylamine compounds by enzymatic assay of lysine-specific demethylase 2 in the presence of NPAC peptide

Journal Article published Feb 2016 in Bioorganic & Medicinal Chemistry Letters volume 26 issue 4 on pages 1193 to 1195

Research funded by Waseda University (2015K-191) | Ministry of Education, Culture, Sports, Science and Technology (26460159) | Japan Society for the Promotion of Science | Core Research for Evolutional Science and Technology | Takeda Science Foundation | Research Foundation for Pharmaceutical Sciences

Authors: Taeko Kakizawa, Tamio Mizukami, Yukihiro Itoh, Makoto Hasegawa, Ryuzo Sasaki, Takayoshi Suzuki

Histone H3 peptide based LSD1-selective inhibitors

Journal Article published May 2015 in Bioorganic & Medicinal Chemistry Letters volume 25 issue 9 on pages 1925 to 1928

Research funded by Ministry of Education, Culture, Sports, Science and Technology (26460159) | Waseda University (2014K-6139) | Core Research for Evolutional Science and Technology | Takeda Science Foundation | Terumo Life Science Foundation | Mochida Memorial Foundation for Medical and Pharmaceutical Research

Authors: Taeko Kakizawa, Yosuke Ota, Yukihiro Itoh, Hiroki Tsumoto, Takayoshi Suzuki

Structural basis for species-specific activation of mouse Toll-like receptor 9

Journal Article published 13 Jul 2018 in FEBS Letters volume 592 issue 15 on pages 2636 to 2646

Research funded by Mochida Memorial Foundation for Medical and Pharmaceutical Research | Daiichi Sankyo Foundation of Life Science | Naito Foundation | Takeda Science Foundation | Grant-in-Aid from the Japanese Ministry of Education, Culture, Sports, Science, and Technology (16H02494, 16H06388, 16K08827, 26711002) | Core Research for Evolutional Science and Technology | Uehara Memorial Foundation

Authors: Hanako Ishida, Umeharu Ohto, Takuma Shibata, Kensuke Miyake, Toshiyuki Shimizu

Novel neurotrophic phenylbutenoids from Indonesian ginger Bangle, Zingiber purpureum

Journal Article published Apr 2015 in Bioorganic & Medicinal Chemistry Letters volume 25 issue 7 on pages 1586 to 1591

Research funded by Ministry of Education, Culture, Sports, Science and Technology (23790035)

Authors: Miwa Kubo, Minori Gima, Kohei Baba, Megumi Nakai, Kenichi Harada, Midori Suenaga, Yoichi Matsunaga, Eishin Kato, Shinya Hosoda, Yoshiyasu Fukuyama

In situ concentration-polarization-enhanced radical graft polymerization of NF270 for mitigating silica fouling and improving pharmaceutical and personal care product rejection

Journal Article published Apr 2018 in Journal of Membrane Science volume 552 on pages 387 to 395

Research funded by Ministry of Science and Technology, Taiwan (103-2221-E-327-003, 104-2221-E-327-001-MY3)

Authors: Yi-Li Lin

Highly selective reduction of nitrobenzenes to azoxybenzenes with a copper catalyst

Journal Article published Apr 2018 in Tetrahedron Letters volume 59 issue 14 on pages 1382 to 1384

Research funded by National Natural Science Foundation of China (21472191, 81773559, 21672050) | International Cooperation Special Grant (2016A050502036) | Science and Technology Development Project of Guangdong Province | International Cooperation Grant (201704030099) | Science and Technology Planning Project of Guangdong Province (2013A022100019) | Chinese Pharmaceutical Association | Yiling Biopharmaceutical Innovation Foundation

Authors: Zhichao Chen, Yatao Qiu, Xiaoxing Wu, Yong Ni, Li Shen, Jun Wu, Sheng Jiang

Modeling the Early Phenotype at the Neuromuscular Junction of Spinal Muscular Atrophy Using Patient-Derived iPSCs

Journal Article published Apr 2015 in Stem Cell Reports volume 4 issue 4 on pages 561 to 568

Research funded by Ministry of Health, Labour and Welfare | Ministry of Education, Culture, Sports, Science and Technology (22110007) | Japan Society for the Promotion of Science | Japan Science and Technology Agency | Core Research for Evolutional Science and Technology | Japan Research Foundation for Clinical Pharmacology | Mochida Memorial Foundation for Medical and Pharmaceutical Research | Intramural Research Grant

Authors: Michiko Yoshida, Shiho Kitaoka, Naohiro Egawa, Mayu Yamane, Ryunosuke Ikeda, Kayoko Tsukita, Naoki Amano, Akira Watanabe, Masafumi Morimoto, Jun Takahashi, Hajime Hosoi, Tatsutoshi Nakahata, Haruhisa Inoue, Megumu K. Saito

Lactones from Ficus auriculata and their effects on the proliferation function of primary mouse osteoblasts in vitro

Journal Article published Aug 2014 in Bioorganic & Medicinal Chemistry Letters volume 24 issue 16 on pages 3952 to 3955

Research funded by Ministry of Science and Technology of China (2011CB512010) | National Natural Science Foundation of China (21166009, 81160391, 81360478, ZDZX2013008-4, 213021, 213017, B2012201044) | Major Technology Project of Hainan | Natural Science Foundation of Hainan Province | Pharmaceutical Joint Research Fundation of the Natural Science Foundation of Hebei Province | China Shiyao Pharmaceutical Group Co., Ltd | Youth Foundation of Hainan Institute of Science and Technology (HKYZQJ2014-07)

Authors: Tai-Ming Shao, Cai-Juan Zheng, Chang-Ri Han, Guang-Ying Chen, Chun-Yan Dai, Xiao-Ping Song, Jin-Chao Zhang, Wen-Hao Chen

Synthesis and biological evaluation of benzimidazole derivatives as the G9a Histone Methyltransferase inhibitors that induce autophagy and apoptosis of breast cancer cells

Journal Article published Jun 2017 in Bioorganic Chemistry volume 72 on pages 168 to 181

Research funded by National Natural Science Fund (81303270, U1303124, 81202403, 81573290) | Liaoning Science and Technology Project (2013226027-4) | Jilin Science and Technology progress project (20130204058YY) | Applied Basic Research Project of Sichuan Science and Technology Department (2013JY0154) | Shenyang Pharmaceutical University Scientific Research Fund (ZCJJ2013407)

Authors: Jin Zhang, Dahong Yao, Yingnan Jiang, Jian Huang, Shilin Yang, Jinhui Wang

Design, synthesis and biological evaluation of coumarin derivatives as novel acetylcholinesterase inhibitors that attenuate H2O2-induced apoptosis in SH-SY5Y cells

Journal Article published Oct 2016 in Bioorganic Chemistry volume 68 on pages 112 to 123

Research funded by National Natural Science Fund (81303270, U1303124, 81202403, 81573290) | Liaoning Science and Technology Project (2013226027-4) | Jilin Science and Technology Progress Project (20130204058YY) | Applied Basic Research Project of Sichuan Science and Technology Department (2013JY0154) | Shenyang Pharmaceutical University Scientific Research Fund (ZCJJ2013407)

Authors: Dahong Yao, Jing Wang, Guan Wang, Yingnan Jiang, Lei Shang, Yuqian Zhao, Jian Huang, Shilin Yang, Jinhui Wang, Yamei Yu

Micellar electrokinetic chromatography of aromatic anions and non-ionic aromatic compounds with stepwise changes of the concentration of cetyltrimethylammonium chloride

Journal Article published May 2012 in Journal of Chromatography A volume 1236 on pages 202 to 206

Research funded by Japan Society for the Promotion of Science (20550082) | Gifu Pharmaceutical University | Koshiyama Science and Technology Foundation

Authors: Yukihiro Esaka, Miki Kobayashi, Hiroya Murakami, Bunji Uno

O-GlcNAc modification affects the ATM-mediated DNA damage response

Journal Article published Oct 2012 in Biochimica et Biophysica Acta (BBA) - General Subjects volume 1820 issue 10 on pages 1678 to 1685

Research funded by Japan Society for the Promotion of Science (20590082) | Ministry of Education, Culture, Sports, Science and Technology (21659022) | Mochida Memorial Foundation for Medical and Pharmaceutical Research

Authors: Yuri Miura, Yoko Sakurai, Tamao Endo

Novel non-trimethoxylphenyl piperlongumine derivatives selectively kill cancer cells

Journal Article published Jun 2017 in Bioorganic & Medicinal Chemistry Letters volume 27 issue 11 on pages 2308 to 2312

Research funded by National Natural Science Foundation of China (81502978, 81673352) | Pharmaceutical Project of Science and Technology of Shanghai (15431901700) | Shanghai ‘‘ChenGuang’’ Project (16CG42)

Authors: Youjun Zhang, Hao Ma, Yuelin Wu, Zhongli Wu, Zhengguang Yao, Wannian Zhang, Chunlin Zhuang, Zhenyuan Miao

TAK1 adaptor proteins, TAB2 and TAB3, link the signalosome to B-cell receptor-induced IKK activation

Journal Article published 18 Aug 2016 in FEBS Letters volume 590 issue 18 on pages 3264 to 3269

Research funded by Ministry of Education, Culture, Sports, Science and Technology (15K08534, 15H01195) | Mochida Memorial Foundation for Medical and Pharmaceutical Research | Takeda Science Foundation

Authors: Hisaaki Shinohara, Tomoharu Yasuda, Tomohiro Kurosaki

Synthetic study of spiroiridal triterpenoids: construction of functionalized spiro[4.5]decane skeleton using Claisen rearrangement of 2-(alkenyl)dihydropyran

Journal Article published Jan 2015 in Tetrahedron Letters volume 56 issue 2 on pages 327 to 330

Research funded by Ministry of Education, Culture, Sports, Science and Technology (19790026) | NOVARTIS Foundation (Japan) for the Promotion of Science | Chugai Pharmaceutical Co. Ltd

Authors: Noriyuki Takanashi, Keiji Tamura, Takahiro Suzuki, Atsuo Nakazaki, Susumu Kobayashi

Simplified method for cell-specific gene expression analysis in Caenorhabditis elegans

Journal Article published Jul 2014 in Biochemical and Biophysical Research Communications volume 450 issue 1 on pages 330 to 334

Research funded by Japan Society for the Promotion of Science | Japan Science and Technology Agency | Mochida Memorial Foundation for Medical and Pharmaceutical Research

Authors: Takuma Sugi, Yasuko Ohtani

Catalytic Dehydrogenative C–H Imidation of Arenes Enabled by Photo-generated Hole Donation to Sulfonimide

Journal Article published Mar 2017 in Chem volume 2 issue 3 on pages 383 to 392

Research funded by Japan Science and Technology Agency | Japan Society for the Promotion of Science (JP26888007) | Takeda Pharmaceutical Company | Sumitomo Foundation | World Premier International Research Center

Authors: Eri Ito, Tomohiro Fukushima, Takahiro Kawakami, Kei Murakami, Kenichiro Itami