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Tissue distribution and safety evaluation of a claudin-targeting molecule, the C-terminal fragment of Clostridium perfringens enterotoxin

Journal Article published Feb 2014 in European Journal of Pharmaceutical Sciences volume 52 on pages 132 to 137

Research funded by Ministry of Education, Culture, Sports, Science and Technology (21689006, 24390042) | Ministry of Health, Labour and Welfare | Takeda Science Foundation | Nakatomi Foundation | Japan Science and Technology Agency

Authors: Xiangru Li, Rie Saeki, Akihiro Watari, Kiyohito Yagi, Masuo Kondoh

Activation of B1a Cells in Peritoneal Cavity by T Cell-Independent Antigen Expressed on Polymeric Micelle

Journal Article published May 2015 in Journal of Pharmaceutical Sciences volume 104 issue 5 on pages 1839 to 1847

Research funded by Japan Science and Technology Agency | Ministry of Education, Culture, Sports, Science and Technology

Authors: Cheol Joo Kim, Eri Hara, Akira Shimizu, Manabu Sugai, Shunsaku Kimura

Effect of laser irradiation on the stability of a photo-sensitive active pharmaceutical ingredient by Raman microscopy

Journal Article published Nov 2012 in Journal of Pharmaceutical and Biomedical Analysis volume 70 on pages 259 to 264

Research funded by Ministry of Education, Culture, Sports, Science and Technology

Authors: Hiroshi Uchida, Kinya Eguchi, Makoto Otsuka

Exocytic and endocytic membrane trafficking in axon development

Journal Article published May 2015 in Development, Growth & Differentiation volume 57 issue 4 on pages 291 to 304

Research funded by Japan Science and Technology Agency | Ministry of Education, Culture, Sports, Science and Technology (23110005) | Japan Society for the Promotion of Science (24500393, 22700353) | Mochida Memorial Foundation for Medical and Pharmaceutical Research

Authors: Takuro Tojima, Hiroyuki Kamiguchi

Innovative approach for identifying root causes of glass defects in sterile drug product manufacturing

Journal Article published Jun 2017 in European Journal of Pharmaceutical Sciences volume 104 on pages 162 to 170

Research funded by Japan Society for the Promotion of Science | Ministry of Education, Culture, Sports, Science and Technology (26820343)

Authors: Lukas Eberle, Alexander Svensson, Andreas Graser, Joerg Luemkemann, Hirokazu Sugiyama, Rainer Schmidt, Konrad Hungerbuehler

Self-micellizing solid dispersion of cyclosporine A for pulmonary delivery: Physicochemical, pharmacokinetic and safety assessments

Journal Article published Jan 2017 in European Journal of Pharmaceutical Sciences volume 96 on pages 107 to 114

Research funded by Ministry of Education, Culture, Sports, Science and Technology (24590200) | Takeda Science Foundation

Authors: Hiroki Suzuki, Kodai Ueno, Takahiro Mizumoto, Yoshiki Seto, Hideyuki Sato, Satomi Onoue

An Evolutionary Search Algorithm for Covariate Models in Population Pharmacokinetic Analysis

Journal Article published Sep 2017 in Journal of Pharmaceutical Sciences volume 106 issue 9 on pages 2407 to 2411

Research funded by Ministry of Education, Culture, Sports, Science and Technology (23136102) | Japan Society for the Promotion of Science (25670073, 15K08071)

Authors: Fumiyoshi Yamashita, Atsuto Fujita, Yukako Sasa, Yuriko Higuchi, Masahiro Tsuda, Mitsuru Hashida

Practical issues and new horizons in MS, NMOSD and related disorders

Journal Article published Jan 2017 in Clinical and Experimental Neuroimmunology volume 8 on pages 1 to 2

Research funded by Ono Pharmaceutical | Ministry of Education, Culture, Sports, Science and Technology (22229008, 26293205) | Asahi Kasei Medical | Ministry of Health, Labour and Welfare | Nihon Pharmaceutical | The Chemo-Sero-Therapeutic Research Institute | Mitsubishi Tanabe Pharma | Genzyme | Biogen Idec | Teva Pharmaceutical Industries | Chugai Pharmaceutical | Teijin Pharma | Bayer Schering

Authors: Kazuo Fujihara

Safety evaluation of a human chimeric monoclonal antibody that recognizes the extracellular loop domain of claudin-2

Journal Article published May 2018 in European Journal of Pharmaceutical Sciences volume 117 on pages 161 to 167

Research funded by Ministry of Health, Labour, and Welfare of Japan | Ministry of Education, Culture, Sports, Science and Technology (24390042) | Japan Science and Technology Agency | Takeda Science Foundation | National Institute of Biomedical Innovation

Authors: Yosuke Hashimoto, Tomoyuki Hata, Minoru Tada, Manami Iida, Akihiro Watari, Yoshiaki Okada, Takefumi Doi, Hiroki Kuniyasu, Kiyohito Yagi, Masuo Kondoh

Optical screening of diabetes mellitus using non-invasive Fourier-transform infrared spectroscopy technique for human lip

Journal Article published Mar 2013 in Journal of Pharmaceutical and Biomedical Analysis volume 76 on pages 169 to 176

Research funded by Gifu University | Japan Science and Technology Agency (No.08000853 and 10006042) | Ministry of Education, Culture, Sports, Science and Technology | Grant-in-Aid for Scientific Research

Authors: Satoshi Yoshida, Makoto Yoshida, Mayumi Yamamoto, Jun Takeda

Structure and function of toll-like receptor 8

Journal Article published Apr 2014 in Microbes and Infection volume 16 issue 4 on pages 273 to 282

Research funded by Ministry of Education, Culture, Sports, Science and Technology | Core Research for Evolutional Science and Technology | Takeda Science Foundation | Mochida Memorial Foundation for Medical and Pharmaceutical Research

Authors: Umeharu Ohto, Hiromi Tanji, Toshiyuki Shimizu

One day prediction of nighttime VLF amplitudes using nonlinear autoregression and neural network modeling

Journal Article published Jan 2017 in Radio Science volume 52 issue 1 on pages 132 to 145

Research funded by Ministry of Education, Culture, Sports, Science and Technology | Directorate General of Higher Education of Indonesian Government

Authors: H. Santosa, Y. Hobara

Increased L1 Retrotransposition in the Neuronal Genome in Schizophrenia

Journal Article published Jan 2014 in Neuron volume 81 issue 2 on pages 306 to 313

Research funded by Ministry of Education, Culture, Sports, Science and Technology | Ministry of Health, Labour and Welfare | Core Research for Evolutional Science and Technology | Japan Science and Technology Agency | Collaborative Research Project of the Brain Research Institute, Niigata University | Takeda Pharmaceutical

Authors: Miki Bundo, Manabu Toyoshima, Yohei Okada, Wado Akamatsu, Junko Ueda, Taeko Nemoto-Miyauchi, Fumiko Sunaga, Michihiro Toritsuka, Daisuke Ikawa, Akiyoshi Kakita, Motoichiro Kato, Kiyoto Kasai, Toshifumi Kishimoto, Hiroyuki Nawa, Hideyuki Okano, Takeo Yoshikawa, Tadafumi Kato, Kazuya Iwamoto

EF-G2mt Is an Exclusive Recycling Factor in Mammalian Mitochondrial Protein Synthesis

Journal Article published Aug 2009 in Molecular Cell volume 35 issue 4 on pages 502 to 510

Research funded by Japan Science and Technology Agency | Mochida Memorial Foundation for Medical and Pharmaceutical Research | Uehara Memorial Foundation | Deutsche Forschungsgemeinschaft (175/15-1) | Ministry of Education, Culture, Sports, Science and Technology

Authors: Masafumi Tsuboi, Hiroyuki Morita, Yusuke Nozaki, Kenta Akama, Takuya Ueda, Koichi Ito, Knud H. Nierhaus, Nono Takeuchi

A novel antibiotic-delivery system by using ovotransferrin as targeting molecule

Journal Article published Jan 2015 in European Journal of Pharmaceutical Sciences volume 66 on pages 59 to 69

Research funded by Ministry of Education, Culture, Sports, Science and Technology (23580177)

Authors: Hisham R. Ibrahim, Sayuri Tatsumoto, Hajime Ono, Filip Van Immerseel, Ruth Raspoet, Takeshi Miyata

Quantitative analysis of isomeric (l-α-, l-β-, d-α-, d-β-) aspartyl residues in proteins from elderly donors

Journal Article published Dec 2015 in Journal of Pharmaceutical and Biomedical Analysis volume 116 on pages 25 to 33

Research funded by Ministry of Education, Culture, Sports, Science and Technology (25288075)

Authors: Noriko Fujii, Takumi Takata, Norihiko Fujii

Enantioselective analysis of d- and l-amino acids from mouse macrophages using high performance liquid chromatography

Journal Article published Dec 2015 in Journal of Pharmaceutical and Biomedical Analysis volume 116 on pages 101 to 104

Research funded by Ministry of Education, Culture, Sports, Science and Technology (S1311044)

Authors: Shiro Kato, Yuki Masuda, Morichika Konishi, Tadao Oikawa

Pharmaceutical evaluation of steroidal ointments by ATR-IR chemical imaging: Distribution of active and inactive pharmaceutical ingredients

Journal Article published Apr 2012 in International Journal of Pharmaceutics volume 426 issue 1-2 on pages 54 to 60

Research funded by Ministry of Education, Culture, Sports, Science and Technology | Scientific Research (20366628)

Authors: Yoshihisa Yamamoto, Toshiro Fukami, Tatsuo Koide, Toyofumi Suzuki, Yukio Hiyama, Kazuo Tomono

Effects of duration of phenytoin administration on mRNA expression of cytochrome P450 and P-glycoprotein in the liver and small intestine of rats

Journal Article published Oct 2016 in Asian Journal of Pharmaceutical Sciences volume 11 issue 5 on pages 662 to 667

Research funded by Ministry of Education, Culture, Sports, Science and Technology (S1411037)

Authors: Atsushi Kawase, Hiroyuki Tanaka, Toru Otori, Kenji Matsuyama, Masahiro Iwaki

Improved oral absorption profile of itraconazole in hypochlorhydria by self-micellizing solid dispersion approach

Journal Article published Jan 2017 in European Journal of Pharmaceutical Sciences volume 97 on pages 55 to 61

Research funded by Ministry of Education, Culture, Sports, Science and Technology (22790043)

Authors: Yoshiki Kojo, Saori Matsunaga, Hiroki Suzuki, Hideyuki Sato, Yoshiki Seto, Satomi Onoue