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Nanomedicine and tumor heterogeneity: Concept and complex reality

Journal Article published Aug 2016 in Nano Today volume 11 issue 4 on pages 402 to 414

Research funded by Canadian Institutes of Health Research (#102569)

Authors: Sandra N. Ekdawi, David A. Jaffray, Christine Allen

Modeling Current Density Maps Using Aliev–Panfilov Electrophysiological Heart Model

Journal Article published 29 Jun 2016 in Cardiovascular Engineering and Technology volume 7 issue 3 on pages 238 to 253

Research funded by Canadian Institutes of Health Research (111253)

Authors: M. Beheshti, F. H. Foomany, K. Magtibay, S. Masse, P. Lai, J. Asta, D. A. Jaffray, K. Nanthakumar, S. Krishnan, K. Umapathy

Quantifying hypoxia in human cancers using static PET imaging

Journal Article published 25 Oct 2016 in Physics in Medicine and Biology volume 61 issue 22 on pages 7957 to 7974

Research funded by Terry Fox Research Institute | Canadian Institutes of Health Research | Quantitative Imaging Network (NIH)

Authors: Edward Taylor, Ivan Yeung, Harald Keller, Bradley G Wouters, Michael Milosevic, David W Hedley, David A Jaffray

Validation of biomechanical deformable image registration in the abdomen, thorax, and pelvis in a commercial radiotherapy treatment planning system

Journal Article published 1 Jun 2017 in Medical Physics volume 44 issue 7 on pages 3407 to 3417

Research funded by Canadian Institutes of Health Research | National Institutes of Health (5RO1CA124714)

Authors: Michael Velec, Joanne L. Moseley, Stina Svensson, Björn Hårdemark, David A. Jaffray, Kristy K. Brock

A framework for noise-power spectrum analysis of multidimensional images

Journal Article published 28 Oct 2002 in Medical Physics volume 29 issue 11 on pages 2655 to 2671

Research funded by National Institutes of Health (R01-CA89081-01) | Cancer Research Program (DAMD-17-98-1-8497) | Canadian Institutes of Health Research (MOP-15631) | Ontario Research and Development Challenge

Authors: J. H. Siewerdsen, I. A. Cunningham, D. A. Jaffray

Tumor perfusion imaging predicts the intra-tumoral accumulation of liposomes

Journal Article published Nov 2013 in Journal of Controlled Release volume 172 issue 1 on pages 351 to 357

Research funded by Terry Fox New Frontiers Program | Canadian Institutes of Health Research

Authors: Shawn Stapleton, Christine Allen, Melania Pintilie, David A Jaffray

Spatial and temporal mapping of heterogeneity in liposome uptake and microvascular distribution in an orthotopic tumor xenograft model

Journal Article published Jun 2015 in Journal of Controlled Release volume 207 on pages 101 to 111

Research funded by Canadian Institutes of Health Research (#102569) | GlaxoSmithKline

Authors: Sandra N. Ekdawi, James M.P. Stewart, Michael Dunne, Shawn Stapleton, Nicholas Mitsakakis, Yannan N. Dou, David A. Jaffray, Christine Allen

Fully automated treatment planning for head and neck radiotherapy using a voxel-based dose prediction and dose mimicking method

Journal Article published 6 Jul 2017 in Physics in Medicine & Biology volume 62 issue 15 on pages 5926 to 5944

Research funded by Natural Sciences and Engineering Research Council of Canada | Canadian Institutes of Health Research

Authors: Chris McIntosh, Mattea Welch, Andrea McNiven, David A Jaffray, Thomas G Purdie

Vulnerabilities of radiomic signature development: The need for safeguards

Journal Article published Nov 2018 in Radiotherapy and Oncology

Research funded by Canadian Institutes of Health Research | Ontario Institute for Cancer Research | Terry Fox Research Institute

Authors: Mattea L. Welch, Chris McIntosh, Benjamin Haibe-Kains, Michael F. Milosevic, Leonard Wee, Andre Dekker, Shao Hui Huang, Thomas G. Purdie, Brian O'Sullivan, Hugo J.W.L. Aerts, David A. Jaffray

Altered brain morphology after focal radiation reveals impact of off-target effects: implications for white matter development and neurogenesis

Journal Article published 2 Nov 2017 in Neuro-Oncology volume 20 issue 6 on pages 788 to 798

Research funded by Canadian Institutes of Health Research (FRN119320) | Ontario Institute for Cancer Research (IA-024)

Authors: Kiran G Beera, Yu-Qing Li, Jun Dazai, James Stewart, Shannon Egan, Mashal Ahmed, C Shun Wong, David A Jaffray, Brian J Nieman

Radiation and Heat Improve the Delivery and Efficacy of Nanotherapeutics by Modulating Intratumoral Fluid Dynamics

Journal Article published 13 Jul 2018 in ACS Nano volume 12 issue 8 on pages 7583 to 7600

Research funded by Canadian Institutes of Health Research (PJT 155905) | Terry Fox Research Institute (PPG14-1036) | Natural Sciences and Engineering Research Council of Canada

Authors: Shawn Stapleton, Michael Dunne, Michael Milosevic, Charles W. Tran, Matthew J. Gold, Ali Vedadi, Trevor D. Mckee, Pamela S. Ohashi, Christine Allen, David A. Jaffray

The Use of Quantitative Imaging in Radiation Oncology: A Quantitative Imaging Network (QIN) Perspective

Journal Article published Nov 2018 in International Journal of Radiation Oncology*Biology*Physics volume 102 issue 4 on pages 1219 to 1235

Research funded by Canadian Institutes of Health Research (137992) | AbbVie | Celgene | National Cancer Institute

Authors: Robert H. Press, Hui-Kuo G. Shu, Hyunsuk Shim, James M. Mountz, Brenda F. Kurland, Richard L. Wahl, Ella F. Jones, Nola M. Hylton, Elizabeth R. Gerstner, Robert J. Nordstrom, Lori Henderson, Karen A. Kurdziel, Bhadrasain Vikram, Michael A. Jacobs, Matthias Holdhoff, Edward Taylor, David A. Jaffray, Lawrence H. Schwartz, David A. Mankoff, Paul E. Kinahan, Hannah M. Linden, Philippe Lambin, Thomas J. Dilling, Daniel L. Rubin, Lubomir Hadjiiski, John M. Buatti