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Towards automation of glycomic profiling of complex biological materials

Journal Article published Jun 2018 in Glycoconjugate Journal volume 35 issue 3 on pages 311 to 321

Research funded by Biotechnology and Biological Sciences Research Council (BB/K016164/1, BB/F008309/1) | FP7 Health (278535) | IBCarb network and BBSRC

Authors: Archana Shubhakar, Poh-Choo Pang, Daryl L. Fernandes, Anne Dell, Daniel I. R. Spencer, Stuart M. Haslam

A critical role for nucleoporin 358 (Nup358) in transposon silencing and piRNA biogenesis inDrosophila

Journal Article published 7 May 2018 in Journal of Biological Chemistry volume 293 issue 24 on pages 9140 to 9147

Research funded by National Institute of Environmental Health Sciences (R00ES021736) | Hollings Cancer Center, Medical University of South Carolina (P30CA138313) | National Institutes of Health (DP1CA174418)

Authors: Rasesh Y. Parikh, Haifan Lin, Vamsi K. Gangaraju

Long repeating (TTAGGG)nsingle-stranded DNA self-condenses into compact beaded filaments stabilized by G-quadruplex formation

Journal Article published 19 Apr 2018 in Journal of Biological Chemistry volume 293 issue 24 on pages 9473 to 9485

Research funded by National Institute of General Medical Sciences (GM31819, GM080176) | National Institute of Environmental Health Sciences (ESO13773)

Authors: Anirban Kar, Nathan Jones, N. Özlem Arat, Richard Fishel, Jack D. Griffith

Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi

Journal Article published 13 Jun 2018 in BioData Mining volume 11 issue 1

Research funded by National Institute of Environmental Health Sciences (T32ES007329, P42ES005948, P30ES025128) | U.S. Environmental Protection Agency (STAR RD83516602)

Authors: Kimberly T. To, Rebecca C. Fry, David M. Reif

Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation

Journal Article published Jul 2017 in Molecular Cell volume 67 issue 1 on pages 106 to 116.e4

Research funded by Biotechnology and Biological Sciences Research Council (BB/N007816) | Wellcome Trust Investigator Award (WT/098412)

Authors: Robert Glyde, Fuzhou Ye, Vidya Chandran Darbari, Nan Zhang, Martin Buck, Xiaodong Zhang

Production of biological nanoparticles from bovine serum albumin as controlled release carrier for curcumin delivery

Journal Article published Aug 2018 in International Journal of Biological Macromolecules volume 115 on pages 83 to 89

Research funded by Zanjan University of Medical Sciences (A-12-430-22)

Authors: Marziyeh Salehiabar, Hamed Nosrati, Elham Javani, Faezeh Aliakbarzadeh, Hamidreza Kheiri Manjili, Soodabeh Davaran, Hossein Danafar

miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development

Journal Article published Sep 2017 in Developmental Biology volume 429 issue 1 on pages 321 to 334

Research funded by National Eye Institute–National Institutes of Health (R21 EY19759) | Vanderbilt University | Department of Biological Sciences

Authors: Nergis Kara, Chunyao Wei, Alexander C. Commanday, James G. Patton

HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1to disrupt centrosome homeostasis

Journal Article published 3 May 2018 in Journal of Biological Chemistry volume 293 issue 24 on pages 9448 to 9460

Research funded by Natural Sciences and Engineering Research Council of Canada (RGPIN2016–04002) | Canadian Institutes of Health Research (HOP143169)

Authors: Delowar Hossain, Jérémy A. Ferreira Barbosa, Éric A. Cohen, William Y. Tsang

Heme bioavailability and signaling in response to stress in yeast cells

Journal Article published 19 Jun 2018 in Journal of Biological Chemistry on page jbc.RA118.002125

Research funded by National Institute of General Medical Sciences (GM118744) | National Institute of Environmental Health Sciences (ES025661) | National Science Foundation (MCB-1552791) | Georgia Institute of Technology (start-up)

Authors: David A. Hanna, Rebecca Hu, Hyojung Kim, Osiris Martinez-Guzman, Matthew P. Torres, Amit R. Reddi

Structural analysis and anticoagulant activities of two sulfated polysaccharides from the sea cucumber Holothuria coluber

Journal Article published Aug 2018 in International Journal of Biological Macromolecules volume 115 on pages 1055 to 1062

Research funded by National Natural Science Foundation of China (81673330, 81703374, 81773737) | Yunnan Provincial Science and Technology Department in China (2014FB078, 2016FA050) | Health and Family Planning Commission of Yunnan Province (L201625) | Youth Innovation Promotion Association of the Chinese Academy of Sciences (2017435) | Chinese Academy of Sciences. (ZSTH-020)

Authors: Wenjiao Yang, Ying Cai, Ronghua Yin, Lisha Lin, Zhongkun Li, Mingyi Wu, Jinhua Zhao

Trichostatin A inhibits deacetylation of histone H3 and p53 by SIRT6

Journal Article published Jan 2018 in Archives of Biochemistry and Biophysics volume 638 on pages 8 to 17

Research funded by National Institutes of Health (1R15GM123393) | National Institute of General Medical Sciences (P20GM103449) | Albany College of Pharmacy and Health Sciences

Authors: Marci Wood, Stacia Rymarchyk, Song Zheng, Yana Cen

Deletion of ferroportin in murine myeloid cells increases iron accumulation and stimulates osteoclastogenesisin vitroandin vivo

Journal Article published 3 May 2018 in Journal of Biological Chemistry volume 293 issue 24 on pages 9248 to 9264

Research funded by Chinese Natural Science Fund (81501843) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR062012, AR068509) | National Institutes of Health (R01 DE025659) | National Institute of General Medical Sciences (GM109005) | National Institute of Environmental Health Sciences (ES022781)

Authors: Lei Wang, Bin Fang, Toshifumi Fujiwara, Kimberly Krager, Akshita Gorantla, Chaoyuan Li, Jian Q. Feng, Michael L. Jennings, Jian Zhou, Nukhet Aykin-Burns, Haibo Zhao

Inhibition of CD36 reduces visceral fat accumulation and improves insulin resistance in diet-induced obese BDNFVal66Metmice

Journal Article published 18 Jun 2018 in Journal of Biological Chemistry on page jbc.RA118.002405

Research funded by National Institutes of Health (HL082511, HL082511, NS077897) | Sanofi (Sanofi Innovation Awards Program (iAwards))

Authors: Jiwon Yang, Keun Woo Park, Sunghee Cho

Advances on the Transfer of Lipids by Lipid Transfer Proteins

Journal Article published Jul 2017 in Trends in Biochemical Sciences volume 42 issue 7 on pages 516 to 530

Research funded by MRC (MR/J006580/1) | Biotechnology and Biological Sciences Research Council (BB/P003818/1) | CNRS and a Marie Curie Grant (6319977)

Authors: Louise H. Wong, Alenka Čopič, Tim P. Levine

Ca 2+ Release Channels Join the ‘Resolution Revolution’

Journal Article published Jul 2017 in Trends in Biochemical Sciences volume 42 issue 7 on pages 543 to 555

Research funded by National Institutes of Health (R01AR060037, R01HL061503) | Fondation Leducq (708572)

Authors: Ran Zalk, Andrew R. Marks

Amazing Diversity in Biochemical Roles of Fe(II)/2-Oxoglutarate Oxygenases

Journal Article published Jul 2018 in Trends in Biochemical Sciences volume 43 issue 7 on pages 517 to 532

Research funded by National Institutes of Health (GM063584)

Authors: Caitlyn Q Herr, Robert P. Hausinger

RecA: Regulation and Mechanism of a Molecular Search Engine

Journal Article published Jun 2016 in Trends in Biochemical Sciences volume 41 issue 6 on pages 491 to 507

Research funded by National Institutes of Health (GM41347, GM62653, GM64745, CA154920, T32 GM007377) | Congressionally Directed Medical Research Programs (W81XWH-13-1-0322)

Authors: Jason C. Bell, Stephen C. Kowalczykowski

Inositol trisphosphate receptor-mediated Ca2+ signalling stimulates mitochondrial function and gene expression in core myopathy patients

Journal Article published 25 Apr 2018 in Human Molecular Genetics volume 27 issue 13 on pages 2367 to 2382

Research funded by Action Medical Research (GN2158) | Medical Research Council to the Neuromuscular Centre Biobank (GTB12001D) | University College London COMPLeX | MDUK | Telethon (GEP12066, GGP16026) | Ricerca Finalizzata, Italian Ministry of Health (RF-2013–02359065) | Biotechnology and Biological Sciences Research Council (BB/L020874/1, BB/P018726/1) | Dubowitz Neuromuscular Centre | NHSE | NSCT | Great Ormond Street Hospital for Children NHS Foundation Trust | Diagnostic Service for Congenital Myopathies | British Heart Foundation Fund (SP/08/004) | National Institute of Health Research Biomedical Research Centre

Authors: Matteo Suman, Jenny A Sharpe, Robert B Bentham, Vassilios N Kotiadis, Michela Menegollo, Viviana Pignataro, Jordi Molgó, Francesco Muntoni, Michael R Duchen, Elena Pegoraro, Gyorgy Szabadkai

Diabetic Retinopathy: Pathophysiology and Treatments

Journal Article published 20 Jun 2018 in International Journal of Molecular Sciences volume 19 issue 6 on page 1816

Research funded by Health and Medical Research Fund (04150746)

Authors: Wei Wang, Amy Lo

Pinewood nanobiochar: A unique carrier for the immobilization of crude laccase by covalent bonding

Journal Article published Aug 2018 in International Journal of Biological Macromolecules volume 115 on pages 563 to 571

Research funded by Natural Sciences and Engineering Research Council of Canada (355254) | Ministère des Relations Internationales du Québec (122523)

Authors: Mitra Naghdi, Mehrdad Taheran, Satinder K. Brar, Azadeh Kermanshahi-pour, M. Verma, R.Y. Surampalli