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Genetic control of predominantly error-free replication through an acrolein-derived minor-groove DNA adduct

Journal Article published 12 Jan 2018 in Journal of Biological Chemistry on page jbc.RA117.000962

Research funded by National Institute of Environmental Health Sciences (ES022948, ES020833, P30 ES06676)

Authors: Jung-Hoon Yoon, Richard P. Hodge, Linda C. Hackfeld, Jeseong Park, Jayati Roy Choudhury, Satya Prakash, Louise Prakash

Engineering and Dissecting the Glycosylation Pathway of a Streptococcal Serine-rich Repeat Adhesin

Journal Article published 30 Dec 2016 in Journal of Biological Chemistry volume 291 issue 53 on pages 27354 to 27363

Research funded by Biotechnology and Biological Sciences Research Council | National Institutes of Health (R01DE017954)

Authors: Fan Zhu, Hua Zhang, Tiandi Yang, Stuart M. Haslam, Anne Dell, Hui Wu

Non-enzymatic molecular damage as a prototypic driver of aging

Journal Article published 6 Mar 2017 in Journal of Biological Chemistry volume 292 issue 15 on pages 6029 to 6038

Research funded by Directorate for Biological Sciences (MCB 1611711) | National Institute on Aging (AG021518, AG047745) | National Institutes of Health (GM0625204, GM061603)

Authors: Alexey Golubev, Andrew D. Hanson, Vadim N. Gladyshev

Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039

Journal Article published 14 Apr 2017 in Journal of Biological Chemistry volume 292 issue 22 on pages 9010 to 9021

Research funded by Australian Research Council (FT130101349) | National Health and Medical Research Council (APP1007918) | La Trobe University | Biotechnology and Biological Sciences Research Council (BB/K002465/1)

Authors: Mohd Ishtiaq Anasir, Sofia Caria, Michael A. Skinner, Marc Kvansakul

Engineering and Dissecting the Glycosylation Pathway of a Streptococcal Serine-rich Repeat Adhesin

Journal Article published 14 Nov 2016 in Journal of Biological Chemistry volume 291 issue 53 on pages 27354 to 27363

Research funded by Biotechnology and Biological Sciences Research Council | National Institutes of Health (R01DE017954)

Authors: Fan Zhu, Hua Zhang, Tiandi Yang, Stuart M. Haslam, Anne Dell, Hui Wu

Coordinated Regulation of Intracellular pH by Two Glucose Sensing Pathways in Yeast

Journal Article published 28 Dec 2017 in Journal of Biological Chemistry on page jbc.RA117.000422

Research funded by National Institute of General Medical Sciences (R35GM118105, R35GM118105-S1, R35GM119518) | National Institute of Environmental Health Sciences (P30ES010126)

Authors: Daniel G. Isom, Stephani C. Page, Leonard B. Collins, Nicholas J. Kapolka, Geoffrey J. Taghon, Henrik G. Dohlman

Structural features of human inositol phosphate multikinase rationalize its inositol phosphate kinase and phosphoinositide 3-kinase activities

Journal Article published 7 Sep 2017 in Journal of Biological Chemistry volume 292 issue 44 on pages 18192 to 18202

Research funded by National Institutes of Health | National Institute of Environmental Health Sciences

Authors: Huanchen Wang, Stephen B. Shears

Cadmium and Secondary Structure-dependent Function of a Degron in the Pca1p Cadmium Exporter

Journal Article published 8 Apr 2016 in Journal of Biological Chemistry volume 291 issue 23 on pages 12420 to 12431

Research funded by National Institute of Environmental Health Sciences (ES16337) | Office of Extramural Research, National Institutes of Health (P30GM103335)

Authors: Nathan Smith, Wenzhong Wei, Miaoyun Zhao, Xiaojuan Qin, Javier Seravalli, Heejeong Kim, Jaekwon Lee

Substrate Affinity Differentially Influences Protein Kinase C Regulation and Inhibitor Potency

Journal Article published 23 Aug 2016 in Journal of Biological Chemistry volume 291 issue 42 on pages 21963 to 21970

Research funded by National Institutes of Health (1DP2 CA186752–01, 1-R01-GM-105646–01-A1) | American Heart Association (13SDG14270009) | Life Sciences Research Foundation

Authors: Ruth F. Sommese, Sivaraj Sivaramakrishnan

Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine

Journal Article published 22 Sep 2017 in Journal of Biological Chemistry volume 292 issue 45 on pages 18682 to 18688

Research funded by National Institutes of Health (ES021452, ES022948, ES020833) | National Institute of Environmental Health Sciences (P30 ES06676)

Authors: Jung-Hoon Yoon, Jayati Roy Choudhury, Jeseong Park, Satya Prakash, Louise Prakash

Site-specific Acetylation of Histone H3 Decreases Polymerase β Activity on Nucleosome Core Particlesin Vitro

Journal Article published 31 Mar 2016 in Journal of Biological Chemistry volume 291 issue 21 on pages 11434 to 11445

Research funded by National Institute of Environmental Health Sciences (ES020955, ES002614, ES004106) | National Institute of General Medical Sciences (T32GM008336)

Authors: Yesenia Rodriguez, John M. Hinz, Marian F. Laughery, John J. Wyrick, Michael J. Smerdon

Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane

Journal Article published 12 May 2016 in Journal of Biological Chemistry volume 291 issue 29 on pages 15082 to 15092

Research funded by National Institute of Environmental Health Sciences (ES016337) | National Institute of General Medical Sciences (P30GM103335)

Authors: Nathan Smith, David J. Adle, Miaoyun Zhao, Xiaojuan Qin, Heejeong Kim, Jaekwon Lee

Molecular mechanisms and genomic maps of DNA excision repair inEscherichia coliand humans

Journal Article published 10 Aug 2017 in Journal of Biological Chemistry volume 292 issue 38 on pages 15588 to 15597

Research funded by National Institute of General Medical Sciences (GM118102) | National Institute of Environmental Health Sciences (ES027255)

Authors: Jinchuan Hu, Christopher P. Selby, Sheera Adar, Ogun Adebali, Aziz Sancar

Mfd translocase is necessary and sufficient for transcription-coupled repair inEscherichia coli

Journal Article published 6 Oct 2017 in Journal of Biological Chemistry volume 292 issue 45 on pages 18386 to 18391

Research funded by National Institute of General Medical Sciences (GM118102) | National Institute of Environmental Health Sciences (ES027255)

Authors: Ogun Adebali, Aziz Sancar, Christopher P. Selby

RNA polymerase II is released from the DNA template during transcription-coupled repair in mammalian cells

Journal Article published 27 Dec 2017 in Journal of Biological Chemistry on page jbc.RA117.000971

Research funded by National Institute of General Medical Sciences (GM118102) | National Institute of Environmental Health Sciences (ES027255)

Authors: Yi-Ying CHIOU, Jinchuan Hu, Aziz Sancar, Christopher P. Selby

Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)

Journal Article published 10 Mar 2017 in Journal of Biological Chemistry volume 292 issue 17 on pages 7131 to 7144

Research funded by National Health and Medical Research Council (1061044, 1055134) | Biotechnology and Biological Sciences Research Council (BB/M006883/1)

Authors: Cassandra Koole, Christopher A. Reynolds, Juan C. Mobarec, Caroline Hick, Patrick M. Sexton, Thomas P. Sakmar

The Budding Yeast Ubiquitin Protease Ubp7 Is a Novel Component Involved in S Phase Progression

Journal Article published 6 Jan 2016 in Journal of Biological Chemistry volume 291 issue 9 on pages 4442 to 4452

Research funded by National Institute of General Medical Sciences (GM088413) | Ellison Medical Foundation (AG-NS-0935–12) | Pittsburgh Foundation (KA2014–73920) | Pennsylvania Department of Health | National Institutes of Health (U54HG008540) | Associazione Italiana per la Ricerca sul Cancro (IG14171) | Fondazione Telethon (GGP12160) | National Cancer Institute (P30CA047904) | National Institute of Environmental Health Sciences (ES024872)

Authors: Stefanie Böhm, Barnabas Szakal, Benjamin W. Herken, Meghan R. Sullivan, Michael J. Mihalevic, Faiz F. Kabbinavar, Dana Branzei, Nathan L. Clark, Kara A. Bernstein

The structure and function ofMycobacterium tuberculosisMazF-mt6 toxin provide insights into conserved features of MazF endonucleases

Journal Article published 15 Mar 2017 in Journal of Biological Chemistry volume 292 issue 19 on pages 7718 to 7726

Research funded by Directorate for Biological Sciences (MCB 0953714) | National Institute of General Medical Sciences (P41 GM103403)

Authors: Eric D. Hoffer, Stacey J. Miles, Christine M. Dunham

Sar1 GTPase Activity Is Regulated by Membrane Curvature

Journal Article published 6 Nov 2015 in Journal of Biological Chemistry volume 291 issue 3 on pages 1014 to 1027

Research funded by National Institute of General Medical Sciences (GM110567, GM088151) | Biotechnology and Biological Sciences Research Council (BB/J018236/1)

Authors: Michael G. Hanna, Ioanna Mela, Lei Wang, Robert M. Henderson, Edwin R. Chapman, J. Michael Edwardson, Anjon Audhya

Mechanism of pathogen recognition by human dectin-2

Journal Article published 26 Jun 2017 in Journal of Biological Chemistry volume 292 issue 32 on pages 13402 to 13414

Research funded by Biotechnology and Biological Sciences Research Council (BB/K007718/1) | Wellcome Trust (093599) | National Institute of General Medical Sciences (GM62116)

Authors: Hadar Feinberg, Sabine A. F. Jégouzo, Maximus J. Rex, Kurt Drickamer, William I. Weis, Maureen E. Taylor