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American Parkinson's Disease Foundation
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Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels

Journal Article published 15 Nov 2017 in BMC Neurology volume 17 issue 1

Research funded by National Institute of Neurological Disorders and Stroke (NS075321, NS41509, NS058714, R01-AG035083) | Foundation for Barnes-Jewish Hospital | American Parkinson's Disease Foundation | Michael J. Fox Foundation for Parkinson's Research

Authors: Laura Ibanez, Umber Dube, Benjamin Saef, John Budde, Kathleen Black, Alexandra Medvedeva, Jorge L. Del-Aguila, Albert A. Davis, Joel S. Perlmutter, Oscar Harari, Bruno A. Benitez, Carlos Cruchaga

How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease?

Journal Article published 4 May 2016 in Journal of Neurochemistry volume 139 on pages 131 to 155

Research funded by American Parkinson's Disease Foundation | Michael J. Fox Foundation for Parkinson's Research | National Institutes of Health (NS092530)

Authors: Laura A. Volpicelli-Daley, Deniz Kirik, Lindsay E. Stoyka, David G. Standaert, Ashley S. Harms

Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing

Journal Article published 31 Jan 2018 in RNA volume 24 issue 5 on pages 673 to 687

Research funded by Swedish Alzheimer Foundation | Swedish Parkinson Foundation | Crafoordska Stiftelsen | Magnus Bergvalls Stiftelse | Åke Wiberg Stiftelse | American Parkinson's Disease Foundation (PDF-IRG-1303) | Swedish Neuro Foundation | Kocks Foundation | Åhlén-stiftelsen | Thuring Foundation | OE and Edla Johanssons Foundation | Bente Rexed Foundation | Tore Nilsons Stiftelse för Medicinsk Forskning | Schyberg Foundation | Vetenskapsrådet (K2014-79X-22510-01-1, ÄR-MH-2016-01997) | Lars Hierta foundation | Bagadilico Linnaeus consortium

Authors: Marcus Davidsson, Paula Díaz-Fernández, Marcos Torroba, Oliver D. Schwich, Patrick Aldrin-Kirk, Luis Quintino, Andreas Heuer, Gang Wang, Cecilia Lundberg, Tomas Björklund

Immunosuppressants and risk of Parkinson disease

Journal Article published 31 May 2018 in Annals of Clinical and Translational Neurology volume 5 issue 7 on pages 870 to 875

Research funded by Michael J. Fox Foundation for Parkinson's Research | National Institute of Environmental Health Sciences (K24ES017765) | National Institute of Neurological Disorders and Stroke (R01NS099129) | American Parkinson's Disease Foundation | University of Pennsylvania

Authors: Brad A. Racette, Anat Gross, Scott Martin Vouri, Alejandra Camacho-Soto, Allison W. Willis, Susan Searles Nielsen

α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease

Journal Article published Apr 2015 in Neurobiology of Disease volume 76 on pages 112 to 125

Research funded by National Institute of Mental Health (RO1MH075020) | National Institute of Aging (RO1AG28108) | National Institute of Neurological Disorders and Stroke (RO1NS060041) | American Parkinson's Disease Foundation | National Cancer Institute (P30CA051008, P30-CA051008)

Authors: Joel J. Credle, Patrick A. Forcelli, Michael Delannoy, Adam W. Oaks, Eva Permaul, Deborah L. Berry, Valeriy Duka, Jonathan Wills, Anita Sidhu

Scarless Gene Tagging with One-Step Transformation and Two-Step Selection in Saccharomyces cerevisiae and Schizosaccharomyces pombe

Journal Article published 13 Oct 2016 in PLOS ONE volume 11 issue 10 on page e0163950

Research funded by National Institutes of Health (NS087557) | American Parkinson's Disease Foundation | European Molecular Biology Organization (ALTF 283-2014) | Human Frontier Science Program (LT000717/2015-L)

Authors: Dirk Landgraf, Dann Huh, Erinc Hallacli, Susan Lindquist

Editors: Arthur J. Lustig

Cholesterol-directed nanoparticle assemblies based on single amino acid peptide mutations activate cellular uptake and decrease tumor volume

Journal Article published 2017 in Chem. Sci. volume 8 issue 11 on pages 7552 to 7559

Research funded by American Parkinson's Disease Foundation (Stanley Fahn Junior Faculty Award) | Arnold and Mabel Beckman Foundation (Young Investigator Award) | Burroughs Wellcome Fund (CASI) | Brain and Behavior Research Foundation (Young Investigator Award) | National Natural Science Foundation of China (91529101, 21572057, 21778017)

Authors: Shang Li, Rongfeng Zou, Yaoquan Tu, Junchen Wu, Markita P. Landry

Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity

Journal Article published Mar 2018 in Cell volume 173 issue 1 on pages 62 to 73.e9

Research funded by Canadian Institutes of Health Research (FDN-143264) | Howard Hughes Medical Institute | Glenn Foundation for Medical Research | American Parkinson's Disease Foundation | Picower Institute | Robert A. and Renee E. Belfer Foundation | Edward N. and Della L. Thome Foundation | U.S. Department of Defense (W81XWH14-1-0157) | University of Texas, M.D. Anderson Center | National Institutes of Health (GM025874, R01HG005084, R01HG005853, R0 CA175744, R21 NS087557) | Whitehead Institute for Biomedical Research | Eleanor Schwartz Charitable Foundation | JPB Foundation | Helen Hay Whitney Foundation | American-Italian Cancer Foundation

Authors: Can Kayatekin, Audra Amasino, Giorgio Gaglia, Jason Flannick, Julia M. Bonner, Saranna Fanning, Priyanka Narayan, M. Inmaculada Barrasa, David Pincus, Dirk Landgraf, Justin Nelson, William R. Hesse, Michael Costanzo, Chad L. Myers, Charles Boone, Jose C. Florez, Susan Lindquist

Pallidal stimulation in Parkinson disease differentially modulates local and network β activity

Journal Article published 31 Jul 2018 in Journal of Neural Engineering volume 15 issue 5 on page 056016

Research funded by Casa Colina Rehabilitation Center | American Parkinson's Disease Foundation | National Institute of Neurological Disorders and Stroke (R01 NS097782, R25 NS079198) | UCSF Middle-Career scientist award | National Institute of Biomedical Imaging and Bioengineering (K23 EB014326)

Authors: Mahsa Malekmohammadi, Yalda Shahriari, Nicholas AuYong, Andrew O’Keeffe, Yvette Bordelon, Xiao Hu, Nader Pouratian

Effect of Levodopa-carbidopa Intestinal Gel on Non-motor Symptoms in Patients with Advanced Parkinson's Disease

Journal Article published 20 Sep 2017 in Movement Disorders Clinical Practice volume 4 issue 6 on pages 829 to 837

Research funded by Auspex | AbbVie | Merz Pharmaceuticals | American Parkinson's Disease Foundation | Ipsen Fund | Parkinson's Study Group | Biotie Therapeutics | Alabama Department of Commerce | Allergan | Huntington Study Group | National Institutes of Health (P01NS087997, P20NS087997, R25NS079188, P2CHD086851, P30NS047466) | National Parkinson Foundation | Dystonia Coalition | Veterans Administration | Parkinson Research Foundation | Chelsea

Authors: David G. Standaert, Ramon L. Rodriguez, John T. Slevin, Michael Lobatz, Susan Eaton, Krai Chatamra, Maurizio F. Facheris, Coleen Hall, Kavita Sail, Yash J. Jalundhwala, Janet Benesh