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Accelerate Brain Cancer Cure
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miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients

Journal Article published 23 Apr 2015 in Journal of Neuro-Oncology volume 123 issue 2 on pages 205 to 216

Research funded by National Institutes of Health (UH2 TR000931-0, PO1 2P30CA023100-28) | International S&T Cooperation Program of China (2014DFA31470) | Doris Duke Charitable Foundation (2010052) | Burroughs Wellcome Fund (1006774.01) | Sontag Foundation (Distinguished Scientist Award) | Sidney Kimmel Foundation for Cancer Research (Fund) | Accelerate Brain Cancer Cure (Fund) | William Guy Forbeck Research Foundation (Fund)

Authors: Johnny C. Akers, Valya Ramakrishnan, Ryan Kim, Shirley Phillips, Vivek Kaimal, Ying Mao, Wei Hua, Isaac Yang, Chia-Chun Fu, John Nolan, Ichiro Nakano, Yuanfan Yang, Martin Beaulieu, Bob S. Carter, Clark C. Chen

Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro

Journal Article published Mar 2017 in Molecular Therapy - Nucleic Acids volume 6 on pages 221 to 232

Research funded by National Institutes of Health (U01-NS59821, R01-CA105171) | Accelerate Brain Cancer Cure | American Brain Tumor Association | Musella Foundation For Brain Tumor Research and Information | National Brain Tumor Society | Voices Against Brain Cancer | U.S. Department of Health and Human Services

Authors: Amy H. Lin, Christopher G. Twitty, Ryan Burnett, Andrew Hofacre, Leah A. Mitchell, Fernando Lopez Espinoza, Harry E. Gruber, Douglas J. Jolly

L- MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells

Journal Article published Sep 2016 in Stem Cell Reports volume 7 issue 3 on pages 483 to 495

Research funded by National Institutes of Health (R01 NS065069-07) | Accelerate Brain Cancer Cure | Alex's Lemonade Stand Foundation for Childhood Cancer | Pediatric Cancer Research Foundation | National Cancer Institute (P30CA033572) | TheraBiologics

Authors: Zhongqi Li, Diana Oganesyan, Rachael Mooney, Xianfang Rong, Matthew J. Christensen, David Shahmanyan, Patrick M. Perrigue, Joseph Benetatos, Lusine Tsaturyan, Soraya Aramburo, Alexander J. Annala, Yang Lu, Joseph Najbauer, Xiwei Wu, Michael E. Barish, David L. Brody, Karen S. Aboody, Margarita Gutova

High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma

Journal Article published 30 Jun 2015 in ACS Medicinal Chemistry Letters volume 6 issue 8 on pages 948 to 952

Research funded by Accelerate Brain Cancer Cure | NYSTEM | National Cancer Institute (R01CA161061) | Howard Hughes Medical Institute

Authors: Christine E. Quartararo, Eduard Reznik, Ana C. deCarvalho, Tom Mikkelsen, Brent R. Stockwell

Infiltrative and drug‐resistant slow‐cycling cells support metabolic heterogeneity in glioblastoma

Journal Article published 15 Oct 2018 in The EMBO Journal on page e98772

Research funded by National Cancer Institute (1S10OD020026) | Preston A. Wells, Jr. Endowment (00107592, 1K08CA199224‐01A1) | Accelerate Brain Cancer Cure | National Institute of Neurological Disorders and Stroke (R24 NS086554‐01) | Cancer Research UK | Preston A. Wells, Jr. Brain Tumor Research Fund | Preston A. Wells, Jr. Brain Tumor Fund | American Brain Tumor Association (DG1800014) | Tenovus (TIG2015/L19) | Robert P. Apkarian Integrated Electron Microscopy Core (RPAIEMC) | American Cancer Society (RSG‐13‐031‐01‐DDC)

Authors: Lan B Hoang‐Minh, Florian A Siebzehnrubl, Changlin Yang, Silveli Suzuki‐Hatano, Kyle Dajac, Tyler Loche, Nicholas Andrews, Michael Schmoll Massari, Jaimin Patel, Krisha Amin, Alvin Vuong, Ana Jimenez‐Pascual, Paul Kubilis, Timothy J Garrett, Craig Moneypenny, Christina A Pacak, Jianping Huang, Elias J Sayour, Duane A Mitchell, Matthew R Sarkisian, Brent A Reynolds, Loic P Deleyrolle

Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells

Journal Article published May 2018 in Cell Chemical Biology volume 25 issue 5 on pages 585 to 594.e7

Research funded by Accelerate Brain Cancer Cure | National Institutes of Health (R35CA209896, P01CA087497, R01GM079465) | Howard Hughes Medical Institute

Authors: Kenichi Shimada, Eduard Reznik, Michael E. Stokes, Lakshmi Krishnamoorthy, Pieter H. Bos, Yuyu Song, Christine E. Quartararo, Nen C. Pagano, Darren R. Carpizo, Ana C. deCarvalho, Donald C. Lo, Brent R. Stockwell

Intratumoral Heterogeneity of the Epigenome

Journal Article published Apr 2016 in Cancer Cell volume 29 issue 4 on pages 440 to 451

Research funded by Accelerate Brain Cancer Cure | National Institute of General Medical Sciences | National Science Foundation (1144247) | National Institutes of Health (R01CA163336, R01CA169316, P50CA097257) | Sontag Foundation

Authors: Tali Mazor, Aleksandr Pankov, Jun S. Song, Joseph F. Costello

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma

Journal Article published 1 Jun 2016 in Science Translational Medicine volume 8 issue 341 on pages 341ra75 to 341ra75

Research funded by Accelerate Brain Cancer Cure | National Brain Tumor Society | American Brain Tumor Association | Musella Foundation For Brain Tumor Research and Information | Voices Against Brain Cancer | National Institute of Neurological Disorders and Stroke (U01NS059821)

Authors: Timothy F. Cloughesy, Joseph Landolfi, Daniel J. Hogan, Stephen Bloomfield, Bob Carter, Clark C. Chen, J. Bradley Elder, Steven N. Kalkanis, Santosh Kesari, Albert Lai, Ian Y. Lee, Linda M. Liau, Tom Mikkelsen, Phioanh Leia Nghiemphu, David Piccioni, Tobias Walbert, Alice Chu, Asha Das, Oscar R. Diago, Dawn Gammon, Harry E. Gruber, Michelle Hanna, Douglas J. Jolly, Noriyuki Kasahara, David McCarthy, Leah Mitchell, Derek Ostertag, Joan M. Robbins, Maria Rodriguez-Aguirre, Michael A. Vogelbaum