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Alzheimer's Disease Research Foundation
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An 11-mer Amyloid Beta Peptide Fragment Provokes Chemical Mutations and Parkinsonian Biomarker Aggregation in Dopaminergic Cells: A Novel Road Map for “Transfected” Parkinson’s

Journal Article published 3 Oct 2016 in ACS Chemical Neuroscience volume 7 issue 11 on pages 1519 to 1530

Research funded by Alzheimer's Disease Research Foundation | College of Science, University of Texas at El Paso | El Paso Pain Center

Authors: Parijat Kabiraj, Jose Eduardo Marin, Armando Varela-Ramirez, Mahesh Narayan

A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ 42

Journal Article published Dec 2015 in Alzheimer's & Dementia volume 11 issue 12 on pages 1452 to 1460

Research funded by Alzheimer's Disease Research Foundation (S#13023) | Fonds Wetenschappelijk Onderzoek (G026710N) | Agentschap voor Innovatie door Wetenschap en Technologie (120835) | University of Antwerp Research Fund | Medical Research Foundation Antwerp | Innovative Medicines Initiative (115372, 111477)

Authors: Kristel Sleegers, Karolien Bettens, Arne De Roeck, Caroline Van Cauwenberghe, Elise Cuyvers, Jan Verheijen, Hanne Struyfs, Jasper Van Dongen, Steven Vermeulen, Sebastiaan Engelborghs, Mathieu Vandenbulcke, Rik Vandenberghe, Peter Paul De Deyn, Christine Van Broeckhoven

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

Journal Article published 1 Jan 2015 in FEBS Open Bio volume 5 issue 1 on pages 763 to 773

Research funded by Fonds National pour la Recherche Scientifique | Alzheimer's Disease Research Foundation | Interuniversity Attraction Poles Programme-Belgian Sate-Belgian Science Policy (IAP-P7/16, IAP-P7/13) | National Institutes of Health

Authors: Marie Decock, Laetitia El Haylani, Serena Stanga, Ilse Dewachter, Jean-Noël Octave, Steven O. Smith, Stefan N. Constantinescu, Pascal Kienlen-Campard

Barriers to adopting a Mediterranean diet in Northern European adults at high risk of developing cardiovascular disease

Journal Article published 21 Nov 2017 in Journal of Human Nutrition and Dietetics volume 31 issue 4 on pages 451 to 462

Research funded by Health and Social Care Research and Development Division of the Public Health Agency (HSC R&D Division) | Alzheimer's Disease Research Foundation | National Prevention Research Initiative (MR/J000388/1) | Stroke Association | Diabetes UK | Cancer Research UK | Chief Scientist Office | British Heart Foundation | Wellcome Trust | Department of Health & Social Care | Biotechnology and Biological Sciences Research Council | Medical Research Council | Welsh Assembly Government | World Cancer Research Fund | Economic and Social Research Council | Alzheimer's Association

Authors: S. E. Moore, C. T. McEvoy, L. Prior, J. Lawton, C. C. Patterson, F. Kee, M. Cupples, I. S. Young, K. Appleton, M. C. McKinley, J. V. Woodside

Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment

Journal Article published 2 Apr 2018 in Annals of Clinical and Translational Neurology volume 5 issue 5 on pages 616 to 629

Research funded by National Cancer Institute | Alzheimer's Foundation of America | Alzheimer's Disease Research Foundation | National Institute on Aging (U24 AG21886) | National Institute of Mental Health | U.S. Department of Defense (W81XWH-12-2-0012) | National Institute of Neurological Disorders and Stroke (P30 NS062691) | National Heart, Lung, and Blood Institute | National Institute on Drug Abuse | National Institutes of Health (RC1 AG035610, R01 AG26938, P50 AG023501, P01 AG019724, U01 AG024904) | Tau Consortium | National Human Genome Research Institute

Authors: Yonatan A. Cooper, Daniel Nachun, Deepika Dokuru, Zhongan Yang, Anna M. Karydas, Ginette Serrero, Binbin Yue, Adam L. Boxer, Bruce L. Miller, Giovanni Coppola, Alzheimer's Disease Neuroimaging Initiative

C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease

Journal Article published Dec 2015 in Alzheimer's & Dementia volume 11 issue 12 on pages 1461 to 1469

Research funded by EMIF (115372) | Medical Research Foundation Antwerp | Alzheimer's Disease Research Foundation | Institute Born-Bunge | Agentschap voor Innovatie door Wetenschap en Technologie (140105) | IWT Baekeland (140262) | IWT TGO (120835) | University Antwerp | Vetenskapsrådet (14002) | Torsten Söderbergs Stiftelse | central Biobank facility of the Institute Born-Bunge | Fonds Wetenschappelijk Onderzoek | Antwerp University Research Fund

Authors: Ann De Vos, Dirk Jacobs, Hanne Struyfs, Erik Fransen, Kerstin Andersson, Erik Portelius, Ulf Andreasson, Didier De Surgeloose, Daniëlle Hernalsteen, Kristel Sleegers, Caroline Robberecht, Christine Van Broeckhoven, Henrik Zetterberg, Kaj Blennow, Sebastiaan Engelborghs, Eugeen Vanmechelen

Structural neuroimaging correlates of cognitive status in older adults: A person-oriented approach

Journal Article published Aug 2016 in Journal of Clinical Neuroscience volume 30 on pages 77 to 82

Research funded by Neurotrack Technologies | National Institute of Biomedical Imaging and Bioengineering | Novartis Pharmaceuticals Corporation | Canadian Institutes of Health Research | Pfizer | AbbVie | Alzheimer's Disease Research Foundation (U01 AG024904) | Bristol-Myers Squibb | CereSpir, Inc. | F. Hoffmann-La Roche | National Institute on Aging | Lumosity | Elan Pharmaceuticals, Inc. | IXICO Ltd. | Piramal Imaging | Lundbeck | Takeda Pharmaceutical Company | Transition Therapeutics | Servier | Alzheimer's Disease Neuroimaging Initiative (W81XWH-12-2-0012) | Genentech | Johnson and Johnson | Northern California Institute for Research and Education | Meso Scale Diagnostics | Janssen Research and Development | GE Healthcare | Eli Lilly and Company | Biogen | Merck | Fujirebio Europe | Araclon Biotech | Alzheimer's Association | NeuroRx Research | EuroImmun | BioClinica | Eisai Inc.

Authors: Charles B. Malpas

Physical Health and Cognitive Function Independently Contributed to Functional Disability among Chinese Older Adults: Data from Two Asian Metropolises

Journal Article published 2011 in Journal of Aging Research volume 2011 on pages 1 to 5

Research funded by Alzheimer's Disease Research Foundation (AG05131, MH36408, 03/1/21/17/214, 08/1/21/19/567)

Authors: Lei Feng, Tze-Pin Ng, Yanling He, Chunbo Li, Ee-Heok Kua, Mingyuan Zhang

Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity

Journal Article published 22 Feb 2016 in Acta Neuropathologica volume 131 issue 4 on pages 525 to 537

Research funded by Deutsche Forschungsgemeinschaft (WA1477/6, SFB645, KFO177) | Alzheimer's Disease Research Foundation (12854) | Bundesministerium für Bildung und Forschung (1615608A and 1615608B) | Seventh Framework Programme (FP7-HEALTH-2010-266753-SCR&Tox, COLIPA)

Authors: Sathish Kumar, Oliver Wirths, Kathrin Stüber, Patrick Wunderlich, Philipp Koch, Sandra Theil, Nasrollah Rezaei-Ghaleh, Markus Zweckstetter, Thomas A. Bayer, Oliver Brüstle, Dietmar R. Thal, Jochen Walter

Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies

Journal Article published 15 Jun 2016 in Journal of Neurochemistry volume 138 on pages 54 to 70

Research funded by Canadian Institutes of Health Research | German Helmholtz Association | Alzheimer's Disease Research Foundation

Authors: Ian R. A. Mackenzie, Manuela Neumann

The amyloid-β degradation pattern in plasma—A possible tool for clinical trials in Alzheimer's disease

Journal Article published Jun 2014 in Neuroscience Letters volume 573 on pages 7 to 12

Research funded by JPND | Stiftelsen Gamla Tjänarinnor | Gun och Bertil Stohnes Stiftelse | Alzheimer's Disease Research Foundation | Dementia Association | Knut och Alice Wallenbergs Stiftelse | Wennergren foundation | Svenska Forskningsrådet Formas | Swedish Brain Fund | Magn. Bergvalls Stiftelse

Authors: Josef Pannee, Ulrika Törnqvist, Anni Westerlund, Martin Ingelsson, Lars Lannfelt, Gunnar Brinkmalm, Rita Persson, Johan Gobom, Johan Svensson, Per Johansson, Henrik Zetterberg, Kaj Blennow, Erik Portelius

Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer’s disease

Journal Article published 8 Nov 2018 in Acta Neuropathologica Communications volume 6 issue 1

Research funded by National Institutes of Health (AG006173) | Alzheimer's Disease Research Foundation (NIRG-12-242825)

Authors: Shaomin Li, Ming Jin, Lei Liu, Yifan Dang, Beth L. Ostaszewski, Dennis J. Selkoe

Accumulation of Vesicle-Associated Human Tau in Distal Dendrites Drives Degeneration and Tau Secretion in anIn SituCellular Tauopathy Model

Journal Article published 2012 in International Journal of Alzheimer's Disease volume 2012 on pages 1 to 16

Research funded by Alzheimer's Disease Research Foundation (P30 AG13846)

Authors: Sangmook Lee, WonHee Kim, Zhihan Li, Garth F. Hall

Ellagic Acid Mitigates SNO-PDI Induced Aggregation of Parkinsonian Biomarkers

Journal Article published 8 Oct 2014 in ACS Chemical Neuroscience volume 5 issue 12 on pages 1209 to 1220

Research funded by Alzheimer's Disease Research Foundation

Authors: Parijat Kabiraj, Jose Eduardo Marin, Armando Varela-Ramirez, Emmanuel Zubia, Mahesh Narayan

Domain adaptation for Alzheimer's disease diagnostics

Journal Article published Oct 2016 in NeuroImage volume 139 on pages 470 to 479

Research funded by Neurotrack Technologies | National Institute of Biomedical Imaging and Bioengineering | Novartis Pharmaceuticals Corporation | National Cancer Institute (1K25CA181632-01) | Canadian Institutes of Health Research | Commonwealth Scientific and Industrial Research Organisation | Pfizer | Alzheimer's Disease Research Foundation (5P50AG005134) | Bristol-Myers Squibb | A. A. Martinos Center for Biomedical Imaging (P41RR014075, P41EB015896, U24RR021382) | F. Hoffmann-La Roche | National Institute on Aging | Janssen Alzheimer Immunotherapy Research & Development, LLC. | Genentech Foundation (G-40819) | Elan Pharmaceuticals, Inc. | Alzheimer's Disease Neuroimaging Initiative (ADNI) | IXICO Ltd. | National Institutes of Health (U01 AG024904) | Piramal Imaging | Takeda Pharmaceutical Company | Servier | Genentech | Shared Instrumentation Grants (1S10RR023401, 1S10RR019307, 1S10RR023043) | DOD ADNI (W81XWH-12-2-0012) | Biogen Idec | Northern California Institute for Research and Education | Meso Scale Diagnostics | Massachusetts General Hospital | GE Healthcare | Eli Lilly and Company | Johnson & Johnson Pharmaceutical Research & Development LLC. | Merck | Fujirebio Europe | Harvard NeuroDiscovery Center | Araclon Biotech | Alexander von Humboldt-Stiftung | Alzheimer's Drug Discovery Foundation | Alzheimer's Association | NeuroRx Research | EuroImmun | Nvidia | BioClinica | Eisai Inc. | Medpace | Synarc

Authors: Christian Wachinger, Martin Reuter