Metadata Search
A.P. Giannini Foundation
Page 1 of 23 results
Sort by: relevance publication year Download as CSV

Improved regulatory element prediction based on tissue-specific local epigenomic signatures

Journal Article published 13 Feb 2017 in Proceedings of the National Academy of Sciences volume 114 issue 9 on pages E1633 to E1640

Research funded by Gordon and Betty Moore Foundation (GBMF3034) | National Institutes of Health (R01 MH094670, U01 MH105985, U54 HG006997, IRACDA K12 GM068524) | California Institute for Regenerative Medicine (GC1R-06673-B) | H.A. and Mary K. Chapman Charitable Trust (NA) | A.P. Giannini Foundation (NA) | U.S. Department of Energy (DE-AC02-05CH11231, DE-AC02-05CH11231)

Authors: Yupeng He, David U. Gorkin, Diane E. Dickel, Joseph R. Nery, Rosa G. Castanon, Ah Young Lee, Yin Shen, Axel Visel, Len A. Pennacchio, Bing Ren, Joseph R. Ecker

CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites

Journal Article published Feb 2016 in Journal of Molecular Biology volume 428 issue 4 on pages 709 to 719

Research funded by Howard Hughes Predoctoral Fellowship | National Institutes of Health (F31 CA180378, DP5 OD009180, R21 GM110580, P30 DK063720, R01 GM083960, U54 RR022220, U54 GM094662, P01 AI091575, U01 GM098256) | Krevans Fellowship | Bayer Science and Education Foundation | A.P. Giannini Foundation | National Science Foundation (STC-1231306)

Authors: Peter Cimermancic, Patrick Weinkam, T. Justin Rettenmaier, Leon Bichmann, Daniel A. Keedy, Rahel A. Woldeyes, Dina Schneidman-Duhovny, Omar N. Demerdash, Julie C. Mitchell, James A. Wells, James S. Fraser, Andrej Sali

Impeding DNA Break Repair Enables Oocyte Quality Control

Journal Article published Oct 2018 in Molecular Cell volume 72 issue 2 on pages 211 to 221.e3

Research funded by NICHD Pathway to Independence (K99/R00HD082375) | A.P. Giannini Foundation | National Institute of General Medical Sciences (GM084955)

Authors: Huanyu Qiao, H.B.D. Prasada Rao, Yan Yun, Sumit Sandhu, Jared H. Fong, Manali Sapre, Michael Nguyen, Addy Tham, Benjamin W. Van, Tiffany Y.H. Chng, Amy Lee, Neil Hunter

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering

Journal Article published 7 Jun 2018 in eLife volume 7

Research funded by David and Lucile Packard Foundation | National Cancer Institute (K99CA203002, F31 CA180378, CA191018) | Pew Charitable Trusts | A.P. Giannini Foundation (Postdoctoral Fellowship) | Wellcome Trust | National Institute of General Medical Sciences (GM110580, GM123159, GM124169, GM124149) | University of California (LFR-17-476732) | Kinship Foundation | Helen Hay Whitney Foundation | National Science Foundation (STC-1231306)

Authors: Daniel A Keedy, Zachary B Hill, Justin T Biel, Emily Kang, T Justin Rettenmaier, José Brandão-Neto, Nicholas M Pearce, Frank von Delft, James A Wells, James S Fraser

Carriers of a common variant in the dopamine transporter gene have greater dementia risk, cognitive decline, and faster ventricular expansion

Journal Article published Oct 2015 in Alzheimer's & Dementia volume 11 issue 10 on pages 1153 to 1162

Research funded by National Institute of Biomedical Imaging and Bioengineering | Novartis Pharmaceuticals Corporation | Canadian Institutes of Health Research | Biogen Idec Inc. | Pfizer | Bristol-Myers Squibb | National Institute on Aging | Synarc Inc. | Innogenetics, N.V. | A.P. Giannini Foundation | Janssen Alzheimer Immunotherapy Research & Development, LLC. | Piramal Imaging; Servier | Elan Pharmaceuticals, Inc. | Medpace, Inc. | IXICO Ltd. | National Institutes of Health (R01 MH097268, R01 AG040060, U01 AG024904, P30 AG010129, K01 AG030514) | Takeda Pharmaceutical Company | Alzheimer's Disease Neuroimaging Initiative | Genentech | Northern California Institute for Research and Education | GE Healthcare | Meso Scale Diagnostics, LLC. | Eli Lilly and Company | Johnson & Johnson Pharmaceutical Research & Development LLC. | F. Hoffmann-La Roche Ltd | Merck | Alzheimer's Drug Discovery Foundation | Alzheimer's Association | NeuroRx Research | BioClinica | Eisai Inc.

Authors: Florence F. Roussotte, Boris A. Gutman, Derrek P. Hibar, Sarah K. Madsen, Katherine L. Narr, Paul M. Thompson

Covalent Modifiers of Botulinum Neurotoxin Counteract Toxin Persistence

Journal Article published 20 Dec 2018 in ACS Chemical Biology volume 14 issue 1 on pages 76 to 87

Research funded by National Institute of Neurological Disorders and Stroke (R21 NS106159, R01 NS080833) | National Institute of Diabetes and Digestive and Kidney Diseases (P30 DK034854) | National Institute of Allergy and Infectious Diseases (R01 AI132387, R01 AI139087, R56 AI127455) | National Institute of Child Health and Human Development (P30 HD18655) | Deutsche Forschungsgemeinschaft (LO 2251/2-1) | Burroughs Wellcome Fund | A.P. Giannini Foundation

Authors: Megan Garland, Brett M. Babin, Shin-Ichiro Miyashita, Sebastian Loscher, Yi Shen, Min Dong, Matthew Bogyo

Volterra inverse scattering series method for one-dimensional quantum barrier scattering

Journal Article published 19 May 2017 in International Journal of Quantum Chemistry volume 117 issue 17 on page e25403

Research funded by Ministry of Science and Technology, Taiwan (MOST 104-2113-M-007-016-MY2) | A.H. Schultz-Stiftung zur Förderung Primatologischer Forschung | A.L. Mailman Family Foundation | A.P. Giannini Foundation | Welch Foundation (E-0608)

Authors: Chia-Chun Chou, Jie Yao, Donald J. Kouri

Theta-burst microstimulation in the human entorhinal area improves memory specificity

Journal Article published 24 Oct 2017 in eLife volume 6

Research funded by Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (PBSKP3-124730) | National Institute of Neurological Disorders and Stroke (NS084017, NS058280) | A.P. Giannini Foundation (Postdoctoral Fellowship) | Defense Advanced Research Projects Agency (N66001-14-2-4029) | G. Harold and Leila Y. Mathers Charitable Foundation (09212007)

Authors: Ali S Titiz, Michael R H Hill, Emily A Mankin, Zahra M Aghajan, Dawn Eliashiv, Natalia Tchemodanov, Uri Maoz, John Stern, Michelle E Tran, Peter Schuette, Eric Behnke, Nanthia A Suthana, Itzhak Fried

Hand2 inhibits kidney specification while promoting vein formation within the posterior mesoderm

Journal Article published 2 Nov 2016 in eLife volume 5

Research funded by California Institute for Regenerative Medicine (TG2-01154) | A.P. Giannini Foundation (Postdoctoral Fellowship) | Universidad de los Andes (FAPA) | Vicerrectoria de Investigaciones (P14.160422.007/01) | Colciencias Convocatoria (617-2013-Joven Investigador Fellowship) | National Institutes of Health (R01HL069594, R01HL108599) | March of Dimes Foundation (1-FY16-257)

Authors: Elliot A Perens, Zayra V Garavito-Aguilar, Gina P Guio-Vega, Karen T Peña, Yocheved L Schindler, Deborah Yelon

RARγ is required for mesodermal gene expression prior to gastrulation in Xenopus

Journal Article published 15 Aug 2018 in Development volume 145 issue 18 on page dev147769

Research funded by National Science Foundation (IOS-0719576, IOS-1147236) | A.P. Giannini Foundation

Authors: Amanda Janesick, Weiyi Tang, Toshi Shioda, Bruce Blumberg

Hereditary Autoinflammatory Disorders

Journal Article published Feb 2019 in Immunology and Allergy Clinics of North America volume 39 issue 1 on pages 13 to 29

Research funded by Eunice Kennedy Shriver National Institute of Child Health and Human Development (5K08HD075830) | American Academy of Allergy, Asthma, and Immunology Foundation | Arthritis National Research Foundation | Hartwell Foundation | Thrasher Research Fund | A.P. Giannini Foundation

Authors: Lori Broderick

Inflammasome/IL-1β Responses to Streptococcal Pathogens

Journal Article published 8 Oct 2015 in Frontiers in Immunology volume 6

Research funded by National Institutes of Health (AI077780, AI096837) | A.P. Giannini Foundation

Authors: Christopher N. LaRock, Victor Nizet

qFit-ligand Reveals Widespread Conformational Heterogeneity of Drug-Like Molecules in X-Ray Electron Density Maps

Journal Article published 20 Nov 2018 in Journal of Medicinal Chemistry volume 61 issue 24 on pages 11183 to 11198

Research funded by David and Lucile Packard Foundation | Pew Charitable Trusts | Relay Therapeutics | Stanford University | A.P. Giannini Foundation | National Institute of General Medical Sciences (GM123159, GM124149) | University of California (LFR-17-476732) | Kinship Foundation | Novo Nordisk (NNF15OC0015268) | Office of Integrative Activities (STC-1231306)

Authors: Gydo C. P. van Zundert, Brandi M. Hudson, Saulo H. P. de Oliveira, Daniel A. Keedy, Rasmus Fonseca, Amelie Heliou, Pooja Suresh, Kenneth Borrelli, Tyler Day, James S. Fraser, Henry van den Bedem

Reporting Guidelines and Issues to Consider for Using Intracranial Brain Stimulation in Studies of Human Declarative Memory

Journal Article published 4 Dec 2018 in Frontiers in Neuroscience volume 12

Research funded by National Institutes of Health (NS103802, NS058280) | A.P. Giannini Foundation

Authors: Nanthia Suthana, Zahra M. Aghajan, Emily A. Mankin, Andy Lin

CD103+ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans

Journal Article published 26 Jul 2016 in PLOS Pathogens volume 12 issue 7 on page e1005749

Research funded by National Institute of Allergy and Infectious Diseases (RO1AI093640) | Howard Hughes Medical Institute (Early Career Scientist Award) | A.P. Giannini Foundation (AP Giannini Postdoctoral Research Fellowship)

Authors: Nancy Van Prooyen, C. Allen Henderson, Davina Hocking Murray, Anita Sil

Editors: Bruce S Klein

Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance

Journal Article published 5 Jul 2016 in mBio volume 7 issue 4

Research funded by Singapore International Economic Development Board | National Institute of Allergy and Infectious Diseases (R01AI103058, R01AI090141) | A.P. Giannini Foundation

Authors: Gregory LaMonte, Michelle Yi-Xiu Lim, Melanie Wree, Christin Reimer, Marie Nachon, Victoria Corey, Peter Gedeck, David Plouffe, Alan Du, Nelissa Figueroa, Bryan Yeung, Pablo Bifani, Elizabeth A. Winzeler

An OX40/OX40L interaction directs successful immunity to hepatitis B virus

Journal Article published 21 Mar 2018 in Science Translational Medicine volume 10 issue 433 on page eaah5766

Research funded by National Institutes of Health (R01 DK093646, R56AI091872, P30DK026743, K01DK099405, K12GM081266, T32AI007334-27) | Ibrahim El-Hefni Technical Training Foundation | A.P. Giannini Foundation | Burroughs Wellcome Fund | National Institute of Diabetes and Digestive and Kidney Diseases (NIH F31 DK112607)

Authors: Jean Publicover, Anuj Gaggar, Jillian M. Jespersen, Ugur Halac, Audra J. Johnson, Amanda Goodsell, Lia Avanesyan, Stephen L. Nishimura, Meghan Holdorf, Keith G. Mansfield, Joyce Bousquet Judge, Arya Koshti, Michael Croft, Adil E. Wakil, Philip Rosenthal, Eric Pai, Stewart Cooper, Jody L. Baron

GRHL2-Dependent Enhancer Switching Maintains a Pluripotent Stem Cell Transcriptional Subnetwork after Exit from Naive Pluripotency

Journal Article published Aug 2018 in Cell Stem Cell volume 23 issue 2 on pages 226 to 238.e4

Research funded by National Institutes of Health (R01 GM101180, R01 GM122439) | California Institute of Regenerative Medicine (TG2-01153) | A.P. Giannini Foundation

Authors: Amy F. Chen, Arthur J. Liu, Raga Krishnakumar, Jacob W. Freimer, Brian DeVeale, Robert Blelloch

Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography

Journal Article published 30 Sep 2015 in eLife volume 4

Research funded by National Science Foundation (Graduate Research Fellowship, BioXFEL Postdoctoral Fellowship, MCB-1330685, STC-1231306, DMR-1332208) | National Institutes of Health (GM095887, GM102520, GM094586, OD009180, GM110580, GM103485, GM103393) | Kinship Foundation (Searle Scholar) | Pew Charitable Trusts (Pew Scholar) | David and Lucile Packard Foundation (Packard Fellow) | Howard Hughes Medical Institute (Collaborative Innovation Award (HCIA)) | U.S. Department of Energy (DE-AC02-76SF00515) | SLAC National Laboratory (SLAC-LDRD-0014-13-2) | A.P. Giannini Foundation (Postdoctoral Research Fellowship)

Authors: Daniel A Keedy, Lillian R Kenner, Matthew Warkentin, Rahel A Woldeyes, Jesse B Hopkins, Michael C Thompson, Aaron S Brewster, Andrew H Van Benschoten, Elizabeth L Baxter, Monarin Uervirojnangkoorn, Scott E McPhillips, Jinhu Song, Roberto Alonso-Mori, James M Holton, William I Weis, Axel T Brunger, S Michael Soltis, Henrik Lemke, Ana Gonzalez, Nicholas K Sauter, Aina E Cohen, Henry van den Bedem, Robert E Thorne, James S Fraser

Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease

Journal Article published Mar 2017 in Cell Stem Cell volume 20 issue 3 on pages 329 to 344.e7

Research funded by A.P. Giannini Foundation | Helen Hay Whitney Foundation | Stanford Translational Research and Applied Medicine | New York Stem Cell Foundation | National Institutes of Health (R01CA188055, R24 HL11756) | Ludwig Cancer Institute

Authors: Mark P. Chao, Andrew J. Gentles, Susmita Chatterjee, Feng Lan, Andreas Reinisch, M. Ryan Corces, Seethu Xavy, Jinfeng Shen, Daniel Haag, Soham Chanda, Rahul Sinha, Rachel M. Morganti, Toshinobu Nishimura, Mohamed Ameen, Haodi Wu, Marius Wernig, Joseph C. Wu, Ravindra Majeti