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A.P. Giannini Foundation
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Carriers of a common variant in the dopamine transporter gene have greater dementia risk, cognitive decline, and faster ventricular expansion

Journal Article published Oct 2015 in Alzheimer's & Dementia volume 11 issue 10 on pages 1153 to 1162

Research funded by National Institute of Biomedical Imaging and Bioengineering | Novartis Pharmaceuticals Corporation | Canadian Institutes of Health Research | Biogen Idec Inc. | Pfizer | Bristol-Myers Squibb | National Institute on Aging | Synarc Inc. | Innogenetics, N.V. | A.P. Giannini Foundation | Janssen Alzheimer Immunotherapy Research & Development, LLC. | Piramal Imaging; Servier | Elan Pharmaceuticals, Inc. | Medpace, Inc. | IXICO Ltd. | National Institutes of Health (R01 MH097268, R01 AG040060, U01 AG024904, P30 AG010129, K01 AG030514) | Takeda Pharmaceutical Company | Alzheimer's Disease Neuroimaging Initiative | Genentech | Northern California Institute for Research and Education | GE Healthcare | Meso Scale Diagnostics, LLC. | Eli Lilly and Company | Johnson & Johnson Pharmaceutical Research & Development LLC. | F. Hoffmann-La Roche Ltd | Merck | Alzheimer's Drug Discovery Foundation | Alzheimer's Association | NeuroRx Research | BioClinica | Eisai Inc.

Authors: Florence F. Roussotte, Boris A. Gutman, Derrek P. Hibar, Sarah K. Madsen, Katherine L. Narr, Paul M. Thompson

Theta-burst microstimulation in the human entorhinal area improves memory specificity

Journal Article published 24 Oct 2017 in eLife volume 6

Research funded by Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (PBSKP3-124730) | National Institute of Neurological Disorders and Stroke (NS084017, NS058280) | A.P. Giannini Foundation (Postdoctoral Fellowship) | Defense Advanced Research Projects Agency (N66001-14-2-4029) | G. Harold and Leila Y. Mathers Charitable Foundation (09212007)

Authors: Ali S Titiz, Michael R H Hill, Emily A Mankin, Zahra M Aghajan, Dawn Eliashiv, Natalia Tchemodanov, Uri Maoz, John Stern, Michelle E Tran, Peter Schuette, Eric Behnke, Nanthia A Suthana, Itzhak Fried

Mutations in thePlasmodium falciparumCyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance

Journal Article published 5 Jul 2016 in mBio volume 7 issue 4 on page e00696-16

Research funded by Singapore International Economic Development Board | National Institute of Allergy and Infectious Diseases (R01AI103058, R01AI090141) | A.P. Giannini Foundation

Authors: Gregory LaMonte, Michelle Yi-Xiu Lim, Melanie Wree, Christin Reimer, Marie Nachon, Victoria Corey, Peter Gedeck, David Plouffe, Alan Du, Nelissa Figueroa, Bryan Yeung, Pablo Bifani, Elizabeth A. Winzeler

Hand2 inhibits kidney specification while promoting vein formation within the posterior mesoderm

Journal Article published 2 Nov 2016 in eLife volume 5

Research funded by California Institute for Regenerative Medicine (TG2-01154) | A.P. Giannini Foundation (Postdoctoral Fellowship) | Universidad de los Andes (FAPA) | Vicerrectoria de Investigaciones (P14.160422.007/01) | Colciencias Convocatoria (617-2013-Joven Investigador Fellowship) | National Institutes of Health (R01HL069594, R01HL108599) | March of Dimes Foundation (1-FY16-257)

Authors: Elliot A Perens, Zayra V Garavito-Aguilar, Gina P Guio-Vega, Karen T Peña, Yocheved L Schindler, Deborah Yelon

CD103+ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans

Journal Article published 26 Jul 2016 in PLOS Pathogens volume 12 issue 7 on page e1005749

Research funded by National Institute of Allergy and Infectious Diseases (RO1AI093640) | Howard Hughes Medical Institute (Early Career Scientist Award) | A.P. Giannini Foundation (AP Giannini Postdoctoral Research Fellowship)

Authors: Nancy Van Prooyen, C. Allen Henderson, Davina Hocking Murray, Anita Sil

Editors: Bruce S Klein

Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease

Journal Article published Mar 2017 in Cell Stem Cell volume 20 issue 3 on pages 329 to 344.e7

Research funded by A.P. Giannini Foundation | Helen Hay Whitney Foundation | Stanford Translational Research and Applied Medicine | New York Stem Cell Foundation | National Institutes of Health (R01CA188055, R24 HL11756) | Ludwig Cancer Institute

Authors: Mark P. Chao, Andrew J. Gentles, Susmita Chatterjee, Feng Lan, Andreas Reinisch, M. Ryan Corces, Seethu Xavy, Jinfeng Shen, Daniel Haag, Soham Chanda, Rahul Sinha, Rachel M. Morganti, Toshinobu Nishimura, Mohamed Ameen, Haodi Wu, Marius Wernig, Joseph C. Wu, Ravindra Majeti

Improved regulatory element prediction based on tissue-specific local epigenomic signatures

Journal Article published 13 Feb 2017 in Proceedings of the National Academy of Sciences volume 114 issue 9 on pages E1633 to E1640

Research funded by Gordon and Betty Moore Foundation (GBMF3034) | National Institutes of Health (R01 MH094670, U01 MH105985, U54 HG006997, IRACDA K12 GM068524) | California Institute for Regenerative Medicine (GC1R-06673-B) | H.A. and Mary K. Chapman Charitable Trust (NA) | A.P. Giannini Foundation (NA) | U.S. Department of Energy (DE-AC02-05CH11231, DE-AC02-05CH11231)

Authors: Yupeng He, David U. Gorkin, Diane E. Dickel, Joseph R. Nery, Rosa G. Castanon, Ah Young Lee, Yin Shen, Axel Visel, Len A. Pennacchio, Bing Ren, Joseph R. Ecker

Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw

Journal Article published Feb 2018 in Developmental Cell volume 44 issue 3 on pages 337 to 347.e5

Research funded by National Institute of Dental and Craniofacial Research (R01 DE018405, R35 DE027550, K99 DE026239) | A.P. Giannini Foundation | USC Office of Research | Norris Medical Library

Authors: Lindsey Barske, Pauline Rataud, Kasra Behizad, Lisa Del Rio, Samuel G. Cox, J. Gage Crump

An OX40/OX40L interaction directs successful immunity to hepatitis B virus

Journal Article published 21 Mar 2018 in Science Translational Medicine volume 10 issue 433 on page eaah5766

Research funded by National Institutes of Health (R01 DK093646, R56AI091872, P30DK026743, K01DK099405, K12GM081266, T32AI007334-27) | Ibrahim El-Hefni Technical Training Foundation | A.P. Giannini Foundation | Burroughs Wellcome Fund | National Institute of Diabetes and Digestive and Kidney Diseases (NIH F31 DK112607)

Authors: Jean Publicover, Anuj Gaggar, Jillian M. Jespersen, Ugur Halac, Audra J. Johnson, Amanda Goodsell, Lia Avanesyan, Stephen L. Nishimura, Meghan Holdorf, Keith G. Mansfield, Joyce Bousquet Judge, Arya Koshti, Michael Croft, Adil E. Wakil, Philip Rosenthal, Eric Pai, Stewart Cooper, Jody L. Baron

GRHL2-Dependent Enhancer Switching Maintains a Pluripotent Stem Cell Transcriptional Subnetwork after Exit from Naive Pluripotency

Journal Article published Jul 2018 in Cell Stem Cell

Research funded by National Institutes of Health (R01 GM101180, R01 GM122439) | California Institute of Regenerative Medicine (TG2-01153) | A.P. Giannini Foundation

Authors: Amy F. Chen, Arthur J. Liu, Raga Krishnakumar, Jacob W. Freimer, Brian DeVeale, Robert Blelloch