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Association for Frontotemporal Degeneration
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GSK-3β Overexpression Alters the Dendritic Spines of Developmentally Generated Granule Neurons in the Mouse Hippocampal Dentate Gyrus

Journal Article published 10 Mar 2017 in Frontiers in Neuroanatomy volume 11

Research funded by Ministerio de Economía y Competitividad (SAF-2014-53040-P (Jesús Ávila), SAF 2015-66603-P (Javier de Felipe)) | Alzheimer's Association (2015-NIRG-340709, (María Llorens-Martín)) | Association for Frontotemporal Degeneration (2016 Basic Science Pilot Grant Award (María Llorens-Martín))

Authors: Noemí Pallas-Bazarra, Asta Kastanauskaite, Jesús Avila, Javier DeFelipe, María Llorens-Martín

Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients

Journal Article published 16 Jun 2017 in Human Molecular Genetics volume 26 issue 17 on pages 3421 to 3431

Research funded by National Institutes of Health | National Institute of Neurological Disorders and Stroke (R01NS063964, R21NS089979, R35NS097273, R21NS084528, P01NS084974, P01NS099114, R01NS088689, R01NS093865, R35NS097261, R01NS080882) | U.S. Department of Defense (AL130125) | Amyotrophic Lateral Sclerosis Association | Association for Frontotemporal Degeneration | Muscular Dystrophy Association (#416137) | National Center for Advancing Translational Sciences

Authors: Mercedes Prudencio, Patrick K. Gonzales, Casey N. Cook, Tania F. Gendron, Lillian M. Daughrity, Yuping Song, Mark T.W. Ebbert, Marka van Blitterswijk, Yong-Jie Zhang, Karen Jansen-West, Matthew C. Baker, Michael DeTure, Rosa Rademakers, Kevin B. Boylan, Dennis W. Dickson, Leonard Petrucelli, Christopher D. Link

Psychiatric symptoms in preclinical behavioural-variant frontotemporal dementia inMAPTmutation carriers

Journal Article published 20 Jan 2018 in Journal of Neurology, Neurosurgery & Psychiatry volume 89 issue 5 on pages 449 to 455

Research funded by National Institute of Neurological Disorders and Stroke | Association for Frontotemporal Degeneration

Authors: Gayathri Cheran, Hannah Silverman, Masood Manoochehri, Jill Goldman, Seonjoo Lee, Liwen Wu, Sarah Cines, Emer Fallon, Brendan Desmond Kelly, Diana Angelika Olszewska, Judith Heidebrink, Sarah Shair, Stephen Campbell, Henry Paulson, Timothy Lynch, Stephanie Cosentino, Edward D Huey

Long-read sequencing across the C9orf72 ‘GGGGCC’ repeat expansion: implications for clinical use and genetic discovery efforts in human disease

Journal Article published 21 Aug 2018 in Molecular Neurodegeneration volume 13 issue 1

Research funded by Pharmaceutical Research and Manufacturers of America Foundation (RSGTMT17) | National Institute on Aging (AG049992, AG047327) | U.S. Department of Defense (AL130125) | Association for Frontotemporal Degeneration | National Institute of Neurological Disorders and Stroke (NS097261, NS099631, NS094137, NS097273, NS084974, NS099114, NS088689, NS093865) | Target ALS | National Institute of Neurological Disorders and Stroke (US) (NS084528) | Robert Packard Center for ALS Research, Johns Hopkins University | Robert Packard Center for ALS Research, Johns Hopkins University (US) | Amyotrophic Lateral Sclerosis Association | Florida Department of Health (8AZ10, 6AZ06)

Authors: Mark T. W. Ebbert, Stefan L. Farrugia, Jonathon P. Sens, Karen Jansen-West, Tania F. Gendron, Mercedes Prudencio, Ian J. McLaughlin, Brett Bowman, Matthew Seetin, Mariely DeJesus-Hernandez, Jazmyne Jackson, Patricia H. Brown, Dennis W. Dickson, Marka van Blitterswijk, Rosa Rademakers, Leonard Petrucelli, John D. Fryer

Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers

Journal Article published 6 Apr 2018 in Annals of Clinical and Translational Neurology volume 5 issue 5 on pages 583 to 597

Research funded by Swedish Alzheimer Foundation | Stichting Dioraphte | Alzheimer’s Research UK | MRC Clinician Scientist Fellowship (MR/M008525/1) | National Institute on Aging (P01AG019724, P50AG23501, AG032306, K23AG039414) | ALF Stockholm county council | Brain Research Trust | Swedish Brain Power | Hjärnfonden | Alzheimer Society (AS-PhD-2015-005) | National Institute for Health Research (BRC149/NS/MH) | Association for Frontotemporal Degeneration | Muscular Dystrophy Association | Dutch Research Council | Alzheimer Nederland (WE.09-2014-04) | MRC UK GENFI (MR/M023664/1) | Wolfson Foundation | Target ALS | Spanish National Institute of Health Carlos III (ISCIII) under the aegis of the EU Joint Programme - Neurodegenerative Disease Research (AC14/00013) | ZonMw (733050103) | Medicinska Forskningsrådet | Weston Brain Institute | Robert Packard Center for ALS Research, Johns Hopkins University | Karolinska Institutet doctoral funding & Stratneuro | National Institutes of Health/National Institute of Neurological Disorders and Stroke (R21NS089979, R35NS097273, P01NS099114, U54NS092089, R35NS097261) | European Joint Programme - Neurodegenerative Disease Research and the Netherlands Organisation for Health Research and Development (PreFrontALS: 733051042, RiMod-FTD 733051024) | association of Frontotemporal Dementia | Italian Ministry of Health | Fundacio Marato de TV3 (20143810) | Amyotrophic Lateral Sclerosis Association | Alzheimer's Drug Discovery Foundation

Authors: Lieke H.H. Meeter, Tania F. Gendron, Ana C. Sias, Lize C. Jiskoot, Silvia P. Russo, Laura Donker Kaat, Janne M. Papma, Jessica L. Panman, Emma L. van der Ende, Elise G. Dopper, Sanne Franzen, Caroline Graff, Adam L. Boxer, Howard J. Rosen, Raquel Sanchez-Valle, Daniela Galimberti, Yolande A. L. Pijnenburg, Luisa Benussi, Roberta Ghidoni, Barbara Borroni, Robert Laforce, Marta del Campo, Charlotte E. Teunissen, Rick van Minkelen, Julio C. Rojas, Giovanni Coppola, Dan H. Geschwind, Rosa Rademakers, Anna M. Karydas, Linn Öijerstedt, Elio Scarpini, Giuliano Binetti, Alessandro Padovani, David M. Cash, Katrina M. Dick, Martina Bocchetta, Bruce L. Miller, Jonathan D. Rohrer, Leonard Petrucelli, John C. van Swieten, Suzee E. Lee

Phosphorylated neurofilament heavy chain: A biomarker of survival for C9ORF 72 -associated amyotrophic lateral sclerosis

Journal Article published Jul 2017 in Annals of Neurology volume 82 issue 1 on pages 139 to 146

Research funded by STRENGTH project funded by EU Joint Program-Neurodegenerative | Mayo Clinic Center for Individualized Medicine | NIH NINDS Intramural Research Program (Z01NS003146) | National Institute on Aging (P01AG017586, K23AG042856, P30AG10124) | Robert Packard Center for ALS Research at Johns Hopkins | Association for Frontotemporal Degeneration | National Institute of Neurological Disorders and Stroke (R21NS089979, R01NS078398, R35NS097273, R21NS084528, P01NS084974, R01NS088689, R01NS093865) | Muscular Dystrophy Association (416137, 4365, 172123) | Mayo Clinic Foundation | Department of Defense Amyotrophic Lateral Sclerosis Research Program (AL130125) | National Center for Advancing Translational Sciences | Target ALS | CReATe (U54-NS-092091) | Italian Ministry of Health (RF-2013-02355764) | ALS Therapy Alliance | Amyotrophic Lateral Sclerosis Association | ALS Finding a Cure Foundation

Authors: Tania F. Gendron, Lillian M. Daughrity, Michael G. Heckman, Nancy N. Diehl, Joanne Wuu, Timothy M. Miller, Pau Pastor, John Q. Trojanowski, Murray Grossman, James D. Berry, William T. Hu, Antonia Ratti, Michael Benatar, Vincenzo Silani, Jonathan D. Glass, Mary Kay Floeter, Andreas Jeromin, Kevin B. Boylan, Leonard Petrucelli, the C9ORF72 Neurofilament Study Group

The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia

Journal Article published 2015 in NeuroImage: Clinical volume 9 on pages 283 to 290

Research funded by Larry L. Hillblom Foundation (2012-A-015-FEL, P50-AG03006) | Association for Frontotemporal Degeneration | National Institutes of Health (K01-AG049152)

Authors: Jennifer S. Yokoyama, Luke W. Bonham, Virginia E. Sturm, Babu Adhimoolam, Anna Karydas, Giovanni Coppola, Bruce L. Miller, Katherine P. Rankin

Combining multiple anatomical MRI measures improves Alzheimer's disease classification

Journal Article published 25 Feb 2016 in Human Brain Mapping volume 37 issue 5 on pages 1920 to 1929

Research funded by Nederlandse Organisatie voor Wetenschappelijk Onderzoek (016130677, 05613010, 05613018) | Dioraphte Foundation (09-02-03-00) | Association for Frontotemporal Degeneration

Authors: Frank de Vos, Tijn M. Schouten, Anne Hafkemeijer, Elise G. P. Dopper, John C. van Swieten, Mark de Rooij, Jeroen van der Grond, Serge A. R. B. Rombouts

Analysis of tauopathy research funding between 2006 and 2016 reveals critical gaps in research priorities

Journal Article published Oct 2018 in Alzheimer's & Dementia

Research funded by Association for Frontotemporal Degeneration | BrightFocus Foundation | CurePSP | Weston Brain Institute

Authors: Cara M. Altimus, Kirstie Keller, Patrick Brannelly, Erin Ross, Chang-Ting Lin, Ekemini A.U. Riley, LaTese Briggs, Jeremy Smith, Melissa Stevens

Baseline Performance Predicts tDCS-Mediated Improvements in Language Symptoms in Primary Progressive Aphasia

Journal Article published 30 Jun 2017 in Frontiers in Human Neuroscience volume 11

Research funded by Association for Frontotemporal Degeneration

Authors: Eric M. McConathey, Nicole C. White, Felix Gervits, Sherry Ash, H. Branch Coslett, Murray Grossman, Roy H. Hamilton