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American Association of Pharmaceutical Scientists
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Upper Maastrichtian ammonite biostratigraphy of the Gulf Coastal Plain (Mississippi Embayment, southern USA)

Journal Article published May 2016 in Cretaceous Research volume 60 on pages 128 to 151

Research funded by American Museum of Natural History | Paleontological Society | American Association of Pharmaceutical Scientists | National Science Foundation Graduate Research Fellowship Program (2013171808)

Authors: Ekaterina Larina, Matthew Garb, Neil Landman, Natalie Dastas, Nicolas Thibault, Lucy Edwards, George Phillips, Remy Rovelli, Corinne Myers, Jone Naujokaityte

Mechanism of Action of Mycobacterium tuberculosis Gyrase Inhibitors: A Novel Class of Gyrase Poisons

Journal Article published 10 May 2018 in ACS Infectious Diseases volume 4 issue 8 on pages 1211 to 1222

Research funded by National Cancer Institute (R01 CA077373) | U.S. Department of Veterans Affairs (I01 Bx002198) | American Association of Pharmaceutical Scientists | Pharmaceutical Research and Manufacturers of America Foundation | National Institute of General Medical Sciences (R01 GM126363) | European Molecular Biology Organization

Authors: Elizabeth G. Gibson, Tim R. Blower, Monica Cacho, Ben Bax, James M. Berger, Neil Osheroff

Label-Free, Direct Measurement of Protein Concentrations in Turbid Solutions with a UV–Visible Integrating Cavity Absorbance Spectrometer

Journal Article published 22 Mar 2018 in Analytical Chemistry volume 90 issue 8 on pages 4982 to 4986

Research funded by American Association of Pharmaceutical Scientists | National Institute of General Medical Sciences (5T 32 GM008359-26)

Authors: Nicholas R. Larson, Yangjie Wei, C. Russell Middaugh

Polyplexes assembled from self-peptides and regulatory nucleic acids blunt toll-like receptor signaling to combat autoimmunity

Journal Article published Feb 2017 in Biomaterials volume 118 on pages 51 to 62

Research funded by ASD/R&E (PE0601120D8Z) | National Defense Education Program (#T32 AI089621) | American Association of Pharmaceutical Scientists (# DGE1322106) | Damon Runyon Foundation (# DRR3415) | Young Investigator of the Alliance for Cancer Gene Therapy (# 15051543) | Melanoma Research Alliance (# 348963)

Authors: Krystina L. Hess, James I. Andorko, Lisa H. Tostanoski, Christopher M. Jewell

Design of Polyelectrolyte Multilayers to Promote Immunological Tolerance

Journal Article published 7 Sep 2016 in ACS Nano volume 10 issue 10 on pages 9334 to 9345

Research funded by U.S. Department of Veterans Affairs (I01BX007080, RX000293) | Melanoma Research Alliance (348963) | Division of Graduate Education (DGE1322106) | American Association of Pharmaceutical Scientists | Maryland Innovation Initiative | Division of Chemical, Bioengineering, Environmental, and Transport Systems (1351688) | University of Maryland | Alliance for Cancer Gene Therapy (15051543) | National Multiple Sclerosis Society (PP2103, RG-1501-02968) | Damon Runyon Cancer Research Foundation (DRR3415)

Authors: Lisa H. Tostanoski, Yu-Chieh Chiu, James I. Andorko, Ming Guo, Xiangbin Zeng, Peipei Zhang, Walter Royal, Christopher M. Jewell

Screening Immunomodulators To Skew the Antigen-Specific Autoimmune Response

Journal Article published 7 Dec 2016 in Molecular Pharmaceutics volume 14 issue 1 on pages 66 to 80

Research funded by American Heart Association | University of Kansas | American Association of Pharmaceutical Scientists | American Foundation for Pharmaceutical Education

Authors: Laura Northrup, Bradley P. Sullivan, Brittany L. Hartwell, Aaron Garza, Cory Berkland

Surface plasmon resonance as a high throughput method to evaluate specific and non-specific binding of nanotherapeutics

Journal Article published Dec 2015 in Journal of Controlled Release volume 219 on pages 331 to 344

Research funded by National Institutes of Health (K12NS080223, K25EB018370, K08NS09043) | Congressionally Directed Medical Research Programs (W81XWH-14-1-0324) | American Cancer Society (IRG-97-153-10) | Passano Foundation | Elsa U. Pardee Foundation | Pharmaceutical Research and Manufacturers of America Foundation | American Association of Pharmaceutical Scientists

Authors: Craig S. Schneider, Adip G. Bhargav, Jimena G. Perez, Aniket S. Wadajkar, Jeffrey A. Winkles, Graeme F. Woodworth, Anthony J. Kim

Impact of dose, route, and composition on the immunogenicity of immune polyelectrolyte multilayers delivered on gold templates

Journal Article published 15 Dec 2016 in Biotechnology and Bioengineering volume 114 issue 2 on pages 423 to 431

Research funded by National Science Foundation (#1351688) | Alliance for Cancer Gene Therapy (#15051543) | University of Maryland | Damon Runyon Cancer Research Foundation (#DRR3415) | Melanoma Research Alliance (#348963) | National Institutes of Health (#T32 AI089621) | American Association of Pharmaceutical Scientists

Authors: Peipei Zhang, James I. Andorko, Christopher M. Jewell

Engineering Immunological Tolerance Using Quantum Dots to Tune the Density of Self-Antigen Display

Journal Article published 3 Apr 2017 in Advanced Functional Materials volume 27 issue 22 on page 1700290

Research funded by National Science Foundation (1351688, DGE1322106) | Astrophysics Science Division | National Institutes of Health (T32 AI089621) | American Association of Pharmaceutical Scientists | Damon Runyon Cancer Research Foundation (DRR3415) | Alliance for Cancer Gene Therapy (15051543) | Melanoma Research Alliance (348963) | U.S. Naval Research Laboratory

Authors: Krystina L. Hess, Eunkeu Oh, Lisa H. Tostanoski, James I. Andorko, Kimihiro Susumu, Jeffrey R. Deschamps, Igor L. Medintz, Christopher M. Jewell

Evaluation of DILI Predictive Hypotheses in Early Drug Development

Journal Article published 15 Mar 2017 in Chemical Research in Toxicology volume 30 issue 4 on pages 1017 to 1029

Research funded by American Association of Pharmaceutical Scientists | American Foundation for Pharmaceutical Education | National Institute of General Medical Sciences (R25 GM56847)

Authors: Rosa Chan, Leslie Z. Benet

Evaluation of the relevance of DILI predictive hypotheses in early drug development: review of in vitro methodologies vs. BDDCS classification

Journal Article published 2018 in Toxicology Research volume 7 issue 3 on pages 358 to 370

Research funded by American Association of Pharmaceutical Scientists | American Foundation for Pharmaceutical Education | American College of Toxicology | Society of Toxicology | National Institute of General Medical Sciences (R25 GM56847) | Center for Scientific Review (P30 DK026743)

Authors: Rosa Chan, Leslie Z. Benet

Assembly and Immunological Processing of Polyelectrolyte Multilayers Composed of Antigens and Adjuvants

Journal Article published 18 Jul 2016 in ACS Applied Materials & Interfaces volume 8 issue 29 on pages 18722 to 18731

Research funded by National Cancer Institute (T32 CA154274) | Melanoma Research Alliance (348963) | National Institute of Allergy and Infectious Diseases (T32 AI089621) | Division of Graduate Education (DGE1322106) | American Association of Pharmaceutical Scientists | Alex's Lemonade Stand Foundation for Childhood Cancer | University of Maryland | Alliance for Cancer Gene Therapy (15051543) | Damon Runyon Cancer Research Foundation (DRR3415) | National Science Foundation (1351688)

Authors: Yu-Chieh Chiu, Joshua M. Gammon, James I. Andorko, Lisa H. Tostanoski, Christopher M. Jewell

Modular Vaccine Design Using Carrier-Free Capsules Assembled from Polyionic Immune Signals

Journal Article published 4 Nov 2015 in ACS Biomaterials Science & Engineering volume 1 issue 12 on pages 1200 to 1205

Research funded by National Cancer Institute (T32 CA154274, T32 AI089621) | Alex's Lemonade Stand Foundation for Childhood Cancer | University of Maryland | Melanoma Research Alliance | Alliance for Cancer Gene Therapy | Damon Runyon Cancer Research Foundation | Division of Graduate Education (DGE1322106, 1351688) | American Association of Pharmaceutical Scientists

Authors: Yu-Chieh Chiu, Joshua M. Gammon, James I. Andorko, Lisa H. Tostanoski, Christopher M. Jewell

Multidrug, Anti-HIV Amorphous Solid Dispersions: Nature and Mechanisms of Impacts of Drugs on Each Other’s Solution Concentrations

Journal Article published 25 Sep 2017 in Molecular Pharmaceutics volume 14 issue 11 on pages 3617 to 3627

Research funded by Division of Industrial Innovation and Partnerships (IIP-1312157) | American Association of Pharmaceutical Scientists | Institute for Critical Technologies and Applied Science, Virginia Tech | Division of Materials Research (DMR-1308276, DMR-1309218) | Macromolecules Innovation Institute, Virginia Polytechnic Institute and State University

Authors: Hale Çiğdem Arca, Laura I. Mosquera-Giraldo, Durga Dahal, Lynne S. Taylor, Kevin J. Edgar

Impact of molecular weight on the intrinsic immunogenic activity of poly(beta amino esters)

Journal Article published 23 Jan 2017 in Journal of Biomedical Materials Research Part A volume 105 issue 4 on pages 1219 to 1229

Research funded by American Association of Pharmaceutical Scientists | National Science Foundation (CAREER 1351688) | Alliance for Cancer Gene Therapy (15051543) | Damon Runyon Cancer Research Foundation (DRR3415) | Melanoma Research Alliance (348963) | Alex's Lemonade Stand Foundation for Childhood Cancer (27120) | National Multiple Sclerosis Society (RG-1501-02968)

Authors: James I. Andorko, Kevin G. Pineault, Christopher M. Jewell

Intrinsic immunogenicity of rapidly-degradable polymers evolves during degradation

Journal Article published Mar 2016 in Acta Biomaterialia volume 32 on pages 24 to 34

Research funded by National Science Foundation (1351688) | National Institutes of Health (T32 AI089621) | American Association of Pharmaceutical Scientists | U.S. Department of Defense | Damon Runyon Cancer Research Foundation (DRR3415) | Alliance for Cancer Gene Therapy (15051543) | Melanoma Research Alliance (348963)

Authors: James I. Andorko, Krystina L. Hess, Kevin G. Pineault, Christopher M. Jewell

Mechanistic Design of Chemically Diverse Polymers with Applications in Oral Drug Delivery

Journal Article published 7 Oct 2016 in Biomacromolecules volume 17 issue 11 on pages 3659 to 3671

Research funded by Division of Chemistry (1465154) | American Association of Pharmaceutical Scientists | Division of Materials Research (1308276, 1309218)

Authors: Laura I. Mosquera-Giraldo, Carlos H. Borca, Xiangtao Meng, Kevin J. Edgar, Lyudmila V. Slipchenko, Lynne S. Taylor

Amphiphilic Cellulose Ethers Designed for Amorphous Solid Dispersion via Olefin Cross-Metathesis

Journal Article published 26 Jan 2016 in Biomacromolecules volume 17 issue 2 on pages 454 to 465

Research funded by American Association of Pharmaceutical Scientists | Division of Materials Research (1308276)

Authors: Yifan Dong, Laura I. Mosquera-Giraldo, Lynne S. Taylor, Kevin J. Edgar

Phase Behavior of Drug-Hydroxypropyl Methylcellulose Amorphous Solid Dispersions Produced from Various Solvent Systems: Mechanistic Understanding of the Role of Polymer using Experimental and Theoretical Methods

Journal Article published 6 Jun 2018 in Molecular Pharmaceutics volume 15 issue 8 on pages 3236 to 3251

Research funded by American Association of Pharmaceutical Scientists | U.S. Food and Drug Administration (5U01FD004275) | Pharmaceutical Research and Manufacturers of America Foundation | National Institute for Pharmaceutical Technology and Education

Authors: Naila A. Mugheirbi, Laura I. Mosquera-Giraldo, Carlos H. Borca, Lyudmila V. Slipchenko, Lynne S. Taylor

Short Drug–Light Intervals Improve Liposomal Chemophototherapy in Mice Bearing MIA PaCa-2 Xenografts

Journal Article published 2 Apr 2018 in Molecular Pharmaceutics volume 15 issue 9 on pages 3682 to 3689

Research funded by NIH Office of the Director (DP5 OD017898) | National Institute of Biomedical Imaging and Bioengineering (R01 EB017270) | American Association of Pharmaceutical Scientists | National Science Foundation (1555220)

Authors: Dandan Luo, Kevin A. Carter, Jumin Geng, Xuedan He, Jonathan F. Lovell