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American-Italian Cancer Foundation
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STAT3 and metabolism: How many ways to use a single molecule?

Journal Article published 19 Feb 2014 in International Journal of Cancer volume 135 issue 9 on pages 1997 to 2003

Research funded by American-Italian Cancer Foundation | Italian Cancer Research Association (AIRC IG13009) | San Paolo Foundation and the Truus and Gerrit van Riemsdijk Foundation, Liechtenstein

Authors: Marco Demaria, Annalisa Camporeale, Valeria Poli

Radiation survey around a Liac mobile electron linear accelerator for intraoperative radiation therapy

Journal Article published Mar 2009 in Journal of Applied Clinical Medical Physics volume 10 issue 2 on pages 131 to 138

Research funded by Associazione Italiana per la Ricerca sul Cancro | American-Italian Cancer Foundation | IORT

Authors: Mario Ciocca, Guido Pedroli, Roberto Orecchia, Andrea Guido, Federica Cattani, Raffaella Cambria, Umberto Veronesi

Role of genotype-based approach in the clinical management of adult acute myeloid leukemia with normal cytogenetics

Journal Article published Jun 2014 in Leukemia Research volume 38 issue 6 on pages 649 to 659

Research funded by American-Italian Cancer Foundation

Authors: Antonia Cagnetta, Sophia Adamia, Chirag Acharya, Franco Patrone, Maurizio Miglino, Alessio Nencioni, Marco Gobbi, Michele Cea

Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment

Journal Article published 21 Mar 2017 in Journal for ImmunoTherapy of Cancer volume 5 issue 1

Research funded by American-Italian Cancer Foundation | Gabrielle’s Angel Foundation for Cancer Research | V Foundation for Cancer Research | National Cancer Institute (K08166039)

Authors: Irene Scarfò, Marcela V. Maus

LSD1 dual function in mediating epigenetic corruption of the vitamin D signaling in prostate cancer

Journal Article published 11 Aug 2017 in Clinical Epigenetics volume 9 issue 1

Research funded by American-Italian Cancer Foundation (57-1234) | U.S. Department of Defense (W81XWH-13-1-0276; PC121785) | National Cancer Institute (5R01CA095367-08) | National Institutes of Health (2P30CA016056-37)

Authors: Sebastiano Battaglia, Ellen Karasik, Bryan Gillard, Jennifer Williams, Trisha Winchester, Michael T. Moser, Dominic J Smiraglia, Barbara A. Foster

High-Throughput Indirect Quantitation of 13C Enriched Metabolites Using 1H NMR

Journal Article published 26 Oct 2016 in Analytical Chemistry volume 88 issue 22 on pages 11147 to 11153

Research funded by National Cancer Institute (P30 CA008748) | National Institute of Biomedical Imaging and Bioengineering (R00 EB014328) | Memorial Sloan-Kettering Cancer Center | American-Italian Cancer Foundation

Authors: Valentina Di Gialleonardo, Sui Seng Tee, Hannah N. Aldeborgh, Vesselin Z. Miloushev, Lidia S. Cunha, George D. Sukenick, Kayvan R. Keshari

Towards comprehensive and quantitative proteomics for diagnosis and therapy of human disease

Journal Article published 21 Dec 2016 in PROTEOMICS volume 17 issue 1-2 on page 1600079

Research funded by American-Italian Cancer Foundation | National Institutes of Health (R21 CA188881, P30 CA008748) | Alex's Lemonade Stand Foundation for Childhood Cancer | Gabrielle’s Angel Foundation for Cancer Research | Damon Runyon-Richard Lumsden Foundation Clinical Investigator Program

Authors: Paolo Cifani, Alex Kentsis

IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer

Journal Article published 21 Oct 2016 in Gut volume 67 issue 2 on pages 320 to 332

Research funded by Lustgarten Foundation | National Institutes of Health | American-Italian Cancer Foundation

Authors: Thomas A Mace, Reena Shakya, Jason R Pitarresi, Benjamin Swanson, Christopher W McQuinn, Shannon Loftus, Emily Nordquist, Zobeida Cruz-Monserrate, Lianbo Yu, Gregory Young, Xiaoling Zhong, Teresa A Zimmers, Michael C Ostrowski, Thomas Ludwig, Mark Bloomston, Tanios Bekaii-Saab, Gregory B Lesinski

In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors

Journal Article published Dec 2017 in Cell Metabolism volume 26 issue 6 on pages 830 to 841.e3

Research funded by National Institutes of Health (R00 EB014328) | NIH/NCI Cancer Center Support (P30 CA008748) | Geoffrey Beene Cancer Research Center | Center for Molecular Imaging and Nanotechnology at MSKCC | Starr Cancer Consortium grant (I6-A616) | The Center for Experimental Therapeutics at MSKCC | Commonwealth Foundation for Cancer Research | American-Italian Cancer Foundation

Authors: Lucia Salamanca-Cardona, Hardik Shah, Alex J. Poot, Fabian M. Correa, Valentina Di Gialleonardo, Hui Lui, Vesselin Z. Miloushev, Kristin L. Granlund, Sui S. Tee, Justin R. Cross, Craig B. Thompson, Kayvan R. Keshari

Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity

Journal Article published Mar 2018 in Cell volume 173 issue 1 on pages 62 to 73.e9

Research funded by Canadian Institutes of Health Research (FDN-143264) | Howard Hughes Medical Institute | Glenn Foundation for Medical Research | American Parkinson's Disease Foundation | Picower Institute | Robert A. and Renee E. Belfer Foundation | Edward N. and Della L. Thome Foundation | U.S. Department of Defense (W81XWH14-1-0157) | University of Texas, M.D. Anderson Center | National Institutes of Health (GM025874, R01HG005084, R01HG005853, R0 CA175744, R21 NS087557) | Whitehead Institute for Biomedical Research | Eleanor Schwartz Charitable Foundation | JPB Foundation | Helen Hay Whitney Foundation | American-Italian Cancer Foundation

Authors: Can Kayatekin, Audra Amasino, Giorgio Gaglia, Jason Flannick, Julia M. Bonner, Saranna Fanning, Priyanka Narayan, M. Inmaculada Barrasa, David Pincus, Dirk Landgraf, Justin Nelson, William R. Hesse, Michael Costanzo, Chad L. Myers, Charles Boone, Jose C. Florez, Susan Lindquist

ProteomeGenerator: A Framework for Comprehensive Proteomics Based on de Novo Transcriptome Assembly and High-Accuracy Peptide Mass Spectral Matching

Journal Article published 8 Oct 2018 in Journal of Proteome Research volume 17 issue 11 on pages 3681 to 3692

Research funded by Robertson Foundation | National Cancer Institute (P30 CA008748, R21 CA188881, R01 CA204396) | Gabrielle’s Angel Foundation for Cancer Research | Aplastic Anemia and MDS International Foundation | American Society of Hematology | Rita Allen Foundation | Alex's Lemonade Stand Foundation for Childhood Cancer | Memorial Sloan-Kettering Cancer Center | Lauri Strauss Leukemia Foundation | American-Italian Cancer Foundation | Burroughs Wellcome Fund

Authors: Paolo Cifani, Avantika Dhabaria, Zining Chen, Akihide Yoshimi, Emily Kawaler, Omar Abdel-Wahab, John T. Poirier, Alex Kentsis

TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells

Journal Article published 11 Feb 2016 in eLife volume 5

Research funded by European Commission (PITN-GA-2013-606806) | European Research Council (340551) | Parent Project Muscular Dystrophy (postdoctoral fellowship) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (P30 AR061303) | AFM-Téléthon (postdoctoral felowship) | National Institutes of Health (diversity supplement to 5 R01 AR052779, R01AR056712, R01AR052779) | American Heart Association (postdoctoral fellowship) | California Institute of Regenerative Medicine (TG2-01162) | Agence Nationale de la Recherche (ANR-13-BSV8-0021-03) | American-Italian Cancer Foundation (postdoctoral fellowship)

Authors: Barbora Malecova, Alessandra Dall'Agnese, Luca Madaro, Sole Gatto, Paula Coutinho Toto, Sonia Albini, Tammy Ryan, Làszlò Tora, Pier Lorenzo Puri

Biallelic targeting of expressed genes in mouse embryonic stem cells using the Cas9 system

Journal Article published Sep 2014 in Methods volume 69 issue 2 on pages 171 to 178

Research funded by Leukemia and Lymphoma Society | American-Italian Cancer Foundation | KWF Kankerbestrijding | National Research Service Award Postdoctoral Fellowship (F32GM084637) | National Institutes of Health (R01GM054668)

Authors: Yu Zhang, Fabio Vanoli, Jeannine R. LaRocque, Przemek M. Krawczyk, Maria Jasin

p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity

Journal Article published 22 Jun 2018 in The Journal of Cell Biology volume 217 issue 9 on pages 3183 to 3201

Research funded by American-Italian Cancer Foundation | Harvard University | National Institutes of Health (R01 CA205158) | Roy and Lynne Frank Foundation | Massachusetts General Hospital

Authors: Scott R. Frank, Clemens P. Köllmann, Phi Luong, Giorgio G. Galli, Lihua Zou, André Bernards, Gad Getz, Raffaele A. Calogero, Morten Frödin, Steen H. Hansen

AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity

Journal Article published 28 Jun 2016 in eLife volume 5

Research funded by National Institutes of Health (R01 AI089824, R01 AI081884, AI064705, R01 AI101400, T32 AR007279, T32 AI007019) | Howard Hughes Medical Institute | National Science Foundation (DGE-1122492) | American-Italian Cancer Foundation

Authors: Edward T Schmid, Iris K Pang, Eugenio A Carrera Silva, Lidia Bosurgi, Jonathan J Miner, Michael S Diamond, Akiko Iwasaki, Carla V Rothlin

N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer

Journal Article published Oct 2016 in Cancer Cell volume 30 issue 4 on pages 563 to 577

Research funded by Prostate Cancer Foundation | National Institutes of Health (1R01CA179100-01A1) | Damon Runyon Cancer Research Foundation | U.S. Department of Defense (PC121341) | National Cancer Institute (U01 CA111275) | European Research Council (ERCCoG648670, R01 CA116337) | Pharmaceutical Research and Manufacturers of America Foundation | American-Italian Cancer Foundation

Authors: Etienne Dardenne, Himisha Beltran, Matteo Benelli, Kaitlyn Gayvert, Adeline Berger, Loredana Puca, Joanna Cyrta, Andrea Sboner, Zohal Noorzad, Theresa MacDonald, Cynthia Cheung, Ka Shing Yuen, Dong Gao, Yu Chen, Martin Eilers, Juan-Miguel Mosquera, Brian D. Robinson, Olivier Elemento, Mark A. Rubin, Francesca Demichelis, David S. Rickman

Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells

Journal Article published 11 May 2017 in Science volume 356 issue 6342 on pages 1072 to 1076

Research funded by National Science Foundation (305303, DGE-1122492) | National Institutes of Health (305299, R01 AI089824, 305300, R01CA212376, 309995, R37 AR40072, 305301, T32AI007019, 309994, R37 AR40072) | Howard Hughes Medical Institute (305304) | American-Italian Cancer Foundation (305302)

Authors: Lidia Bosurgi, Y. Grace Cao, Mar Cabeza-Cabrerizo, Andrea Tucci, Lindsey D. Hughes, Yong Kong, Jason S. Weinstein, Paula Licona-Limon, Edward T. Schmid, Facundo Pelorosso, Nicola Gagliani, Joseph E. Craft, Richard A. Flavell, Sourav Ghosh, Carla V. Rothlin

The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection

Journal Article published Oct 2018 in Molecular Cell volume 72 issue 1 on pages 127 to 139.e8

Research funded by NIH/NCI (R01-CA172272, P01-CA174653, R01-CA197774, P01-CA174653, P01-CA174653) | Ovarian Cancer Research Fund Alliance (368964) | Susan G. Komen (CCR16377030) | National Institutes of Health (T32-GM007367, F31-CA200181) | JSPS Overseas Research Fellowships (JSPS-2016180) | Uehara Memorial Foundation Research Fellowship (201740041) | American-Italian Cancer Foundation | Associazione Italiana per la Ricerca sul Cancro

Authors: David Billing, Michiko Horiguchi, Foon Wu-Baer, Angelo Taglialatela, Giuseppe Leuzzi, Silvia Alvarez Nanez, Wenxia Jiang, Shan Zha, Matthias Szabolcs, Chyuan-Sheng Lin, Alberto Ciccia, Richard Baer

Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers

Journal Article published Oct 2017 in Molecular Cell volume 68 issue 2 on pages 414 to 430.e8

Research funded by Fondazione Veronesi | Breast Cancer Alliance | Ines Mandl research fellowship | Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (PP00P3_159323) | H2020 European Research Council (614541, 681630) | Ovarian Cancer Research Fund (368964) | National Institutes of Health (4T32CA009503-30, F31CA210607, R01CA197774) | Susan G. Komen (CCR16377030) | Associazione Italiana per la Ricerca sul Cancro | American-Italian Cancer Foundation | Giovanni Armenise-Harvard Foundation

Authors: Angelo Taglialatela, Silvia Alvarez, Giuseppe Leuzzi, Vincenzo Sannino, Lepakshi Ranjha, Jen-Wei Huang, Chioma Madubata, Roopesh Anand, Brynn Levy, Raul Rabadan, Petr Cejka, Vincenzo Costanzo, Alberto Ciccia

Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

Journal Article published 22 Oct 2018 in The EMBO Journal volume 37 issue 22 on page e100294

Research funded by Pew Charitable Trusts | National Institute of Diabetes and Digestive and Kidney Diseases (P30DK034854, 1R01DK090311, 1R01DK105198, R24OD017870) | HDDC Pilot Feasibility Grant | National Health and Medical Research Council (1146558) | National Institutes of Health | American Liver Foundation | National Institute of General Medical Sciences (T32GM007753) | Stand Up To Cancer | NCI (5P01CA120964, 5P30CA006516) | Claudia Adams Barr Program for Innovative Cancer Research | American-Italian Cancer Foundation | Damon Runyon Cancer Research Foundation

Authors: Andrew G Cox, Allison Tsomides, Dean Yimlamai, Katie L Hwang, Joel Miesfeld, Giorgio G Galli, Brendan H Fowl, Michael Fort, Kimberly Y Ma, Mark R Sullivan, Aaron M Hosios, Erin Snay, Min Yuan, Kristin K Brown, Evan C Lien, Sagar Chhangawala, Matthew L Steinhauser, John M Asara, Yariv Houvras, Brian Link, Matthew G Vander Heiden, Fernando D Camargo, Wolfram Goessling