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American Foundation for Pharmaceutical Education
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Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones

Journal Article published May 2018 in Bioorganic & Medicinal Chemistry volume 26 issue 9 on pages 2354 to 2364

Research funded by National Institutes of Health (5P01 CA125066) | American Foundation for Pharmaceutical Education

Authors: John L. Woodard, Andrew C. Huntsman, Pratiq A. Patel, Hee-Byung Chai, Ragu Kanagasabai, Soumendrakrishna Karmahapatra, Alexandria N. Young, Yulin Ren, Malcolm S. Cole, Denisse Herrera, Jack C. Yalowich, A. Douglas Kinghorn, Joanna E. Burdette, James R. Fuchs

Meeting Proceedings ICBS2016—Translating the Power of Chemical Biology to Clinical Advances

Journal Article published 17 Mar 2017 in ACS Chemical Biology volume 12 issue 4 on pages 869 to 877

Research funded by Naito Foundation | Ministry of Education, Culture, Sports, Science and Technology (15H05371, 15K14937, 24655147) | American Heart Association (15SDG25710427) | American Foundation for Pharmaceutical Education | Japan Science and Technology Agency (10602) | National Institutes of Health (1F31CA203039-01) | Mochida Memorial Foundation for Medical and Pharmaceutical Research

Authors: Yugo Kuriki, Toru Komatsu, Peter D. Ycas, Sara K. Coulup, Erick J. Carlson, William C. K. Pomerantz

Oligopeptide Transport in Rat Lung Alveolar Epithelial Cells is Mediated by Pept2

Journal Article published 22 Aug 2017 in Pharmaceutical Research volume 34 issue 12 on pages 2488 to 2497

Research funded by National Institute of General Medical Sciences (GM59297) | National Heart, Lung, and Blood Institute (HL38578, HL38621, HL38658, HL64365, HL64365, HL64365, HL126877, HL112638) | American Heart Association (9950442N) | American Foundation for Pharmaceutical Education | Pharmaceutical Research and Manufacturers of America Foundation | Hastings and Whittier Foundations

Authors: Hovhannes J. Gukasyan, Tomomi Uchiyama, Kwang-Jin Kim, Carsten Ehrhardt, Sharon K. Wu, Zea Borok, Edward D. Crandall, Vincent H.L. Lee

Design, synthesis, and biological activity of bicyclic radester analogues as Hsp90 inhibitors

Journal Article published Dec 2009 in Bioorganic & Medicinal Chemistry Letters volume 19 issue 24 on pages 6845 to 6850

Research funded by American Foundation for Pharmaceutical Education

Authors: Vinod D. Jadhav, Adam S. Duerfeldt, Brian S.J. Blagg

A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides

Journal Article published 26 Oct 2017 in Molecular Pharmaceutics volume 14 issue 11 on pages 3987 to 3997

Research funded by American Foundation for Pharmaceutical Education | University of Minnesota

Authors: Kimberly M. Maize, Rachit Shah, Alex Strom, Sidath Kumarapperuma, Andrew Zhou, Carston R. Wagner, Barry C. Finzel

Structural and Energetic Analysis of 2-Aminobenzimidazole Inhibitors in Complex with the Hepatitis C Virus IRES RNA Using Molecular Dynamics Simulations

Journal Article published 3 Jun 2014 in Journal of Chemical Information and Modeling volume 54 issue 6 on pages 1758 to 1772

Research funded by National Science Foundation (XSEDE-MCA01S027) | National Institutes of Health (R01-GM081411) | Willard L. Eccles Charitable Foundation | American Foundation for Pharmaceutical Education

Authors: Niel M. Henriksen, Hamed S. Hayatshahi, Darrell R. Davis, Thomas E. Cheatham

Population pharmacokinetic model of transdermal nicotine delivered from a matrix-type patch

Journal Article published 6 Sep 2017 in British Journal of Clinical Pharmacology volume 83 issue 12 on pages 2709 to 2717

Research funded by American Foundation for Pharmaceutical Education (Pre-Doctoral Fellowship in Clinical Pharmaceutical)

Authors: Matthew W. Linakis, Joseph E. Rower, Jessica K. Roberts, Eleanor I. Miller, Diana G. Wilkins, Catherine M. T. Sherwin

A Single Active Site Mutation in the Pikromycin Thioesterase Generates a More Effective Macrocyclization Catalyst

Journal Article published 19 Sep 2017 in Journal of the American Chemical Society volume 139 issue 38 on pages 13456 to 13465

Research funded by Horace H. Rackham School of Graduate Studies, University of Michigan | Division of Biological Infrastructure (1263079) | European Regional Development Fund (CTQ2015-70524-R, RYC-2013- 14706) | College of Pharmacy, University of Michigan | Ministerio de Economía y Competitividad (CTQ2015-70524-R, RYC-2013-14706) | American Foundation for Pharmaceutical Education | National Institutes of Health (GM076477, R35 GM118101)

Authors: Aaron A. Koch, Douglas A. Hansen, Vikram V. Shende, Lawrence R. Furan, K. N. Houk, Gonzalo Jiménez-Osés, David H. Sherman

Neuronal nicotinic receptor ligands modulate chronic nicotine-induced ethanol consumption in C57BL/6J mice

Journal Article published Jul 2012 in Pharmacology Biochemistry and Behavior volume 102 issue 1 on pages 36 to 43

Research funded by American Foundation for Pharmaceutical Education | American Association of Colleges of Pharmacy NIP Research | South Dakota Governor's 2010 Research Initiative | SDSU RS/SF

Authors: Ravi K. Sajja, Shafiqur Rahman

Bryostatin extends tPA time window to 6h following middle cerebral artery occlusion in aged female rats

Journal Article published Oct 2015 in European Journal of Pharmacology volume 764 on pages 404 to 412

Research funded by National Institutes of Health (RO1 NS061954, T32 GM81741) | National Institute of Neurological Disorders and Stroke | American Medical Association Foundation | Neurosurgery Research and Education Foundation | American Foundation for Pharmaceutical Education

Authors: Zhenjun Tan, Brandon P. Lucke-Wold, Aric F. Logsdon, Ryan C. Turner, Cong Tan, Xinlan Li, Jarin Hongpaison, Daniel L. Alkon, James W. Simpkins, Charles L. Rosen, Jason D. Huber

Semisynthesis and Kappa-Opioid Receptor Activity of Derivatives of Columbin, a Furanolactone Diterpene

Journal Article published 18 Jul 2017 in Journal of Natural Products volume 80 issue 7 on pages 2094 to 2100

Research funded by American Foundation for Pharmaceutical Education | National Institute on Drug Abuse (DA018151) | Istanbul Teknik Üniversitesi (40258) | Türkiye Bilimsel ve Teknolojik Araştirma Kurumu (1059B141400648) | National Institute of General Medical Sciences (GM008545, GM111385)

Authors: Anil Yilmaz, Rachel Saylor Crowley, Alexander M. Sherwood, Thomas E. Prisinzano

A Population Pharmacokinetic Analysis of Dextroamphetamine in the Plasma and Hair of Healthy Adults

Journal Article published 2 Sep 2015 in Clinical Drug Investigation volume 35 issue 10 on pages 633 to 643

Research funded by National Institute on Drug Abuse (DA07820, DA07820, DA09026) | Primary Children’s Hospital Foundation (Pharmacotherapy Subspecialty Award) | American Foundation for Pharmaceutical Education

Authors: Jessica K. Roberts, Sarah F. Cook, Chris Stockmann, Douglas E. Rollins, Diana G. Wilkins, Catherine M. T. Sherwin

Northalrugosidine Is a Bisbenzyltetrahydroisoquinoline Alkaloid from Thalictrum alpinum with in Vivo Antileishmanial Activity

Journal Article published 28 Jan 2015 in Journal of Natural Products volume 78 issue 3 on pages 552 to 556

Research funded by National Institute of Allergy and Infectious Diseases (RC4 - AI 076309) | American Foundation for Pharmaceutical Education

Authors: C. Benjamin Naman, Gaurav Gupta, Sanjay Varikuti, Heebyung Chai, Raymond W. Doskotch, Abhay R. Satoskar, A. Douglas Kinghorn

The Extended Clearance Concept Following Oral and Intravenous Dosing: Theory and Critical Analyses

Journal Article published 22 Oct 2018 in Pharmaceutical Research volume 35 issue 12

Research funded by National Institutes of Health (P30 DK026743) | National Science Foundation (114427) | China Scholarship Council | American Foundation for Pharmaceutical Education | National Institute of General Medical Sciences (R25 GM56847)

Authors: Leslie Z. Benet, Christine M. Bowman, Shufang Liu, Jasleen K. Sodhi

GABA Uptake Inhibition Reduces In Vivo Extraction Fraction in the Ventral Tegmental Area of Long Evans Rats Measured by Quantitative Microdialysis Under Transient Conditions

Journal Article published 10 Nov 2017 in Neurochemical Research volume 43 issue 2 on pages 306 to 315

Research funded by American Foundation for Pharmaceutical Education | National Institute on Alcohol Abuse and Alcoholism (AA014874)

Authors: Shannon L. Zandy, Rueben A. Gonzales

Enhanced in vitro activity of tigecycline in the presence of chelating agents

Journal Article published May 2018 in International Journal of Antimicrobial Agents volume 51 issue 5 on pages 799 to 802

Research funded by NIH/NCATS Clinical and Translational Science (UL1 TR000064) | American Foundation for Pharmaceutical Education

Authors: Amelia N. Deitchman, Ravi Shankar Prasad Singh, Kenneth H. Rand, Hartmut Derendorf

Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa

Journal Article published 11 Jul 2016 in Journal of Medicinal Chemistry volume 59 issue 14 on pages 6929 to 6942

Research funded by National Institute of Allergy and Infectious Diseases (AI102883) | American Foundation for Pharmaceutical Education | American Chemical Society

Authors: Geoffrey A. Heinzl, Weiliang Huang, Wenbo Yu, Bennett J. Giardina, Yue Zhou, Alexander D. MacKerell, Angela Wilks, Fengtian Xue

5-Alkyloxytryptamines are membrane-targeting, broad-spectrum antibiotics

Journal Article published Nov 2016 in Bioorganic & Medicinal Chemistry Letters volume 26 issue 22 on pages 5539 to 5544

Research funded by National Institutes of Health (1DP2OD008735) | Human Frontiers Science Program (RGY0076/2013) | American Foundation for Pharmaceutical Education | University of Wisconsin Carbone Cancer Center Cancer Center Support Grant (P30 CA014520)

Authors: Katherine C. Faulkner, Katherine A. Hurley, Douglas B. Weibel

Development of a medication monitoring attitude measure using a mixed methods item development process

Journal Article published 10 Mar 2015 in International Journal of Pharmacy Practice volume 24 issue 1 on pages 49 to 59

Research funded by American Foundation for Pharmaceutical Education

Authors: Matthew J. Witry, Pamela M. Wesely, Amber M. Goedken, Erika J. Ernst, Bernard A. Sorofman, William R. Doucette

Elucidating the role of compression waves and impact duration for generating mild traumatic brain injury in rats

Journal Article published 23 Nov 2016 in Brain Injury volume 31 issue 1 on pages 98 to 105

Research funded by American Medical Association Foundation (NA) | Neurosurgery Research and Education Foundation (NA) | American Foundation for Pharmaceutical Education (NA) | Sigma Xi Grants in Aid of Research (NA)

Authors: Brandon P. Lucke-Wold, Michael Phillips, Ryan C. Turner, Aric F. Logsdon, Kelly E. Smith, Jason D. Huber, Charles L. Rosen, Jonathan D. Regele