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The Impact of Pain and Itch on Functioning and Health-Related Quality of Life in Systemic Sclerosis: An Exploratory Study

Journal Article published Jul 2016 in Journal of Pain and Symptom Management volume 52 issue 1 on pages 43 to 53

Research funded by Lady Davis Institute of Medical Research of the Jewish General Hospital | INOVA Diagnostics Inc. | Cure Scleroderma Foundation | Canadian Institutes of Health Research (FRN 83518) | Pfizer | Euroimmun | Mikrogen GmbH | Actelion Pharmaceuticals | the Canadian Arthritis Network | Scleroderma Society of Ontario | Scleroderma Society of Canada and its Provincial Chapters | Sclérodermie Québec | Fonds de Recherche du Québec - Santé | Dr. Fooke Laboratorien GmbH

Authors: Mélanie Racine, Marie Hudson, Murray Baron, Warren R. Nielson, J. Pope, J. Markland, D. Robinson, N. Jones, N. Khalidi, P. Docherty, E. Kaminska, A. Masseto, E. Sutton, J.-P. Mathieu, S. Ligier, T. Grodzicky, C. Thorne, G. Gyger, D. Smith, P.R. Fortin, M. Larché

Absolute Bioavailability of Ponesimod, a Selective S1P1 Receptor Modulator, in Healthy Male Subjects

Journal Article published 16 Feb 2016 in European Journal of Drug Metabolism and Pharmacokinetics volume 42 issue 1 on pages 129 to 134

Research funded by Actelion Pharmaceuticals

Authors: Margaux Boehler, Pierre-Eric Juif, Matthias Hoch, Jasper Dingemanse

Entry-into-humans study with ACT-462206, a novel dual orexin receptor antagonist, comparing its pharmacodynamics with almorexant

Journal Article published 21 Apr 2014 in The Journal of Clinical Pharmacology volume 54 issue 9 on pages 979 to 986

Research funded by Actelion Pharmaceuticals

Authors: Matthias Hoch, Helene van Gorsel, Joop van Gerven, Jasper Dingemanse

Fli1 deficiency contributes to the downregulation of endothelial protein C receptor in systemic sclerosis: a possible role in prothrombotic conditions

Journal Article published 21 Nov 2015 in British Journal of Dermatology volume 174 issue 2 on pages 338 to 347

Research funded by Ministry of Health, Labour and Welfare | Actelion Pharmaceuticals

Authors: R. Saigusa, Y. Asano, T. Yamashita, T. Taniguchi, T. Takahashi, Y. Ichimura, T. Toyama, A. Yoshizaki, T. Miyagaki, M. Sugaya, S. Sato

Endothelial progenitor cells in relation to endothelin-1 and endothelin receptor blockade: A randomized, controlled trial

Journal Article published Sep 2013 in International Journal of Cardiology volume 168 issue 2 on pages 1017 to 1022

Research funded by Research Council of Sweden | Swedish Heart and Lung Foundation | IZKF Jena | Novo Nordisk Foundation | Karolinska Institutet/Stockholm County Council Strategic Cardiovascular Programme | Gustav V and Queen Victoria Foundation | Actelion Pharmaceuticals | Actelion Research Award

Authors: Christian Jung, Arnar Rafnsson, Kerstin Brismar, John Pernow

Home Exercise Training in Children and Adolescents with Pulmonary Arterial Hypertension: A Pilot Study

Journal Article published 14 Nov 2016 in Pediatric Cardiology volume 38 issue 1 on pages 191 to 198

Research funded by Stiftung Kinderherz (2511-10-13-001) | Actelion Pharmaceuticals

Authors: David Zöller, Jannos Siaplaouras, Anita Apitz, Peter Bride, Michael Kaestner, Heiner Latus, Dietmar Schranz, Christian Apitz

Right ventricular dysfunction and pulmonary hypertension in heart failure with preserved ejection fraction

Journal Article published 13 Oct 2016 in European Journal of Heart Failure volume 18 issue 12 on pages 1488 to 1490

Research funded by Medtronic | Teva and Novartis | Actelion Pharmaceuticals | National Heart, Lung, and Blood Institute (RO1 HL128526, U10 HL110262) | Cardiokinetix | Mast Therapeutics | AstraZeneca | Merck | Amgen | GlaxoSmithKline

Authors: Masaru Obokata, Barry A. Borlaug

Susceptibility ofClostridium difficileisolates from a Phase 2 clinical trial of cadazolid and vancomycin inC. difficileinfection

Journal Article published 3 Oct 2015 in Journal of Antimicrobial Chemotherapy volume 71 issue 1 on pages 213 to 219

Research funded by Actelion Pharmaceuticals | Leon Adams and Beverly La Ferla | Watermeadow Medical

Authors: D. N. Gerding, D. W. Hecht, T. Louie, C. E. Nord, G. H. Talbot, O. A. Cornely, M. Buitrago, E. Best, S. Sambol, J. R. Osmolski, H. Kracker, H. H. Locher, P. Charef, M. Wilcox

Baseline Characteristics of the Korean Registry of Pulmonary Arterial Hypertension

Journal Article published 2015 in Journal of Korean Medical Science volume 30 issue 10 on page 1429

Research funded by Handok, Inc. | Actelion Pharmaceuticals

Authors: Wook-Jin Chung, Yong Bum Park, Chan Hong Jeon, Jo Won Jung, Kwang-Phil Ko, Sung Jae Choi, Hye Sun Seo, Jae Seung Lee, Hae Ok Jung, KORPAH Investigators

Intrauterine endotoxin-induced impairs pulmonary vascular function and right ventricular performance in infant rats and improvement with early vitamin D therapy

Journal Article published 15 Dec 2015 in American Journal of Physiology-Lung Cellular and Molecular Physiology volume 309 issue 12 on pages L1438 to L1446

Research funded by NIH (HL114753, HL114887, HL68702) | Children's Hospital Colorado Research Institute | Actelion Pharmaceuticals | Gilead Sciences

Authors: Erica Mandell, Kyle N. Powers, Julie W. Harral, Gregory J. Seedorf, Kendall S. Hunter, Steven H. Abman, R. Blair Dodson