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Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1–Ras dependent pathway

Journal Article published Feb 2016 in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease volume 1862 issue 2 on pages 284 to 295

Research funded by Ministry of Science, ICT and Future Planning (No. 2231-415) | Alzheimer's Disease Research Center, Emory University (3P50 AG005131) | Alzheimer's Association (NIRG-08-91651) | Kuwait University fellowship

Authors: Nathanael J. Lee, Jung Min Song, Hyun-Ji Cho, You Me Sung, Taehee Lee, Andrew Chung, Sung-Ha Hong, Jessica L. Cifelli, Mark Rubinshtein, Lila K. Habib, Christina C. Capule, R. Scott Turner, Daniel T.S. Pak, Jerry Yang, Hyang-Sook Hoe

C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells

Journal Article published Mar 2016 in Experimental Neurology volume 277 on pages 171 to 177

Research funded by U.S. Department of Defense (11188144) | Amyotrophic Lateral Sclerosis Association (2009) | National Institute of Neurological Disorders and Stroke (R01 MH084880-05, R01 NS080882, P50 NS071674, P01 NS084974) | Johns Hopkins (AG16574-17J) | Alzheimer's Disease Research Center, Emory University | Epigenomics Translational grant (RFA 44.06) | Center for Individualized Medicine | Mayo Clinic | CReATe consortium (U54 NS090291)

Authors: Rustam Esanov, Kinsley C. Belle, Marka van Blitterswijk, Veronique V. Belzil, Rosa Rademakers, Dennis W. Dickson, Leonard Petrucelli, Kevin B. Boylan, Derek M. Dykxhoorn, Joanne Wuu, Michael Benatar, Claes Wahlestedt, Zane Zeier

Closeout of the HALT-PKD trials

Journal Article published Sep 2015 in Contemporary Clinical Trials volume 44 on pages 48 to 55

Research funded by Swanson School of Engineering, University of Pittsburgh (U01DK082230) | Beth Israel Deaconess Medical Center (RR001032, RR025758, UL1TR001102) | National Institute of Diabetes and Digestive and Kidney Diseases | Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic (RR024989, UL1TR000439) | National Center for Research Resources General Clinical Research Centers | Clinical and Translational Science Awards | Fannie Stevens Murphy Memorial Fund, Washington University in St. Louis (U01DK62401) | Tufts Medical Center (U01DK62411, RR000054) | Tufts University (RR025752, UL1TR001064) | University of Kansas Medical Center (RR023940, RR033179, UL1TR000001) | Mayo Clinic (U01DK62410, RR000585, RR024150, UL1TR00135) | Foundation for the National Institutes of Health | Alzheimer's Disease Research Center, Emory University (U01DK62408, RR000039, RR025008, UL1TR000454) | Colorado Power Electronics Center, University of Colorado Boulder (U01DK62402, RR000051, RR025780, UL1TR001082)

Authors: Charity G. Moore, Susan Spillane, Gertrude Simon, Barbara Maxwell, Frederic F. Rahbari-Oskoui, William E. Braun, Arlene B. Chapman, Robert W. Schrier, Vicente E. Torres, Ronald D. Perrone, Theodore I. Steinman, Godela Brosnahan, Peter G. Czarnecki, Peter C. Harris, Dana C. Miskulin, Michael F. Flessner, K. Ty Bae, Kaleab Z. Abebe, Marie C. Hogan

Electron Transfer between Electrically Conductive Minerals and Quinones

Journal Article published 13 Jul 2017 in Frontiers in Chemistry volume 5

Research funded by Alzheimer's Disease Research Center, Emory University (P50AG025688)

Authors: Olga Taran

 Cortical Atrophy is Associated with Accelerated Cognitive Decline in Mild Cognitive Impairment with Subsyndromal Depression

Journal Article published Sep 2017 in The American Journal of Geriatric Psychiatry volume 25 issue 9 on pages 980 to 991

Research funded by University of Tokyo | National Institute of Biomedical Imaging and Bioengineering | Eisai Global Clinical Development | Elan | Avid Radiopharmaceuticals, Inc | Northwestern University | New York Academy of Sciences | Pfizer | U.S. Food and Drug Administration | Sanofi-Aventis Groupe | Bristol-Myers Squibb | Dr. Weiner's academic travel | Dana Foundation | F. Hoffmann-La Roche | Novartis | Kenes, Intl. | Cornell University | National Institute on Aging | National Institute of Mental Health (R01MH098062, R01MH101472, R01MH098062, R01MH101472) | Michael J. Fox Foundation for Parkinson's Research | U.S. Department of Defense | Abbott | AstraZeneca AB | Rockefeller University | Neuroscience School of Advanced Studies (NSAS) | National Institutes of Health (U01 AG024904, P30 AG010129, K01 AG030514, R01 MH098062, R01 MH101472) | University of California, San Diego | AC Immune | Alzheimer's Disease Neuroimaging Initiative | Genentech | Fidelity Biosciences Research Initiative | National Brain Research Centre | Johnson and Johnson | Johns Hopkins Medicine | Biogen Idec | Consortium for Multiple Sclerosis Centers (CMSC) | Kyoto University | ADPD | GE Healthcare | Eli Lilly and Company | University of California, Los Angeles | Otsuka (Asia) | Veterans Administration | Schering-Plough | Bristol-Myers Squibb Canada | Avid Radiopharmaceuticals, Inc. | Memorial Sloan-Kettering Cancer Center | University of Pennsylvania | ADCS | Merck | Araclon | Nutricia | Alzheimer's Disease Research Center, Emory University | Alzheimer's Drug Discovery Foundation | Alzheimer's Association | Bayer Schering Pharma AG | Innogenetics | GlaxoSmithKline | California Department of Public Health | Medpace | University Center Hospital, Toulouse | Synarc

Authors: Mitzi M. Gonzales, Philip S. Insel, Craig Nelson, Duygu Tosun, Niklas Mattsson, Susanne G. Mueller, Simona Sacuiu, David Bickford, Michael W. Weiner, R. Scott Mackin

Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases

Journal Article published Jan 2012 in Neurobiology of Aging volume 33 issue 1 on pages 204.e13 to 204.e15

Research funded by Alzheimer's Disease Research Center, Emory University (AG025688) | Emory NINDS Neuroscience Core Facilities (NS055077)

Authors: Thomas S. Wingo, Ami Rosen, David J. Cutler, James J. Lah, Allan I. Levey

Hypertension and obesity moderate the relationship between β-amyloid and cognitive decline in midlife

Journal Article published Oct 2018 in Alzheimer's & Dementia

Research funded by National Institutes of Health (R01 AG021155, R01 AG027161) | National Center for Advancing Translational Sciences (UL1TR00427) | Waisman Center | National Institute of Child Health and Human Development (P30 HD03352) | Alzheimer's Disease Research Center, Emory University (P50 AG033514, R01AG037639, R01 AG054059, F30 AG054115, T32 GM007507, T32 GM008692, T32 CA009206)

Authors: Lindsay R. Clark, Rebecca L. Koscik, Samantha L. Allison, Sara E. Berman, Derek Norton, Cynthia M. Carlsson, Tobey J. Betthauser, Barbara B. Bendlin, Bradley T. Christian, Nathanial Chin, Sanjay Asthana, Sterling C. Johnson

Computer versus Compensatory Calendar Training in Individuals with Mild Cognitive Impairment: Functional Impact in a Pilot Study

Journal Article published 6 Sep 2017 in Brain Sciences volume 7 issue 12 on page 112

Research funded by Alzheimer's Association (NIRG-07-58843) | Alzheimer's Disease Research Center, Emory University (AG025688) | Patient-Centered Outcomes Research Institute (PCORI-CER-1306-01897) | National Center for Advancing Translational Sciences (UL1 TR000135)

Authors: Melanie Chandler, Dona Locke, Noah Duncan, Sherrie Hanna, Andrea Cuc, Julie Fields, Charlene Hoffman Snyder, Angela Lunde, Glenn Smith

More than memory impairment in voltage-gated potassium channel complex encephalopathy

Journal Article published 1 Jul 2014 in European Journal of Neurology volume 21 issue 10 on pages 1301 to 1310

Research funded by National Institute of Neurological Disorders and Stroke (N01-NS-0-2328) | National Institute on Aging (K23AG042492, K23AG021989, R01AG031189, P01AG021601) | Alzheimer's Association (NIRP-12-259223) | National Center for Advancing Translational Sciences (KL2TR000143) | Alzheimer's Disease Research Center, Emory University (P50AG023501) | National Institute of Health (UL1RR024131)

Authors: B. M. Bettcher, J. M. Gelfand, S. R. Irani, J. Neuhaus, S. Forner, C. P. Hess, M. D. Geschwind

Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels

Journal Article published Oct 2017 in Neuron volume 96 issue 2 on pages 355 to 372.e6

Research funded by Alzheimer's Disease Research Center, Emory University (ADRC2013) | Competitive Medical Research (UPMC- CMRF2013) | Whitehall Foundation (2013-05-70) | R21 (MH107966)

Authors: Yanjun Zhao, Sivaprakash Sivaji, Michael C. Chiang, Haadi Ali, Monica Zukowski, Sareen Ali, Bryan Kennedy, Alex Sklyar, Alice Cheng, Zihan Guo, Alexander K. Reed, Ravindra Kodali, Jennifer Borowski, Georgia Frost, Patrick Beukema, Zachary P. Wills

A pilot randomized trial of two cognitive rehabilitation interventions for mild cognitive impairment: caregiver outcomes

Journal Article published 24 Feb 2017 in International Journal of Geriatric Psychiatry volume 32 issue 12 on pages e180 to e187

Research funded by National Institute of Nursing Research (R01 NR012419) | Alzheimer's Disease Research Center, Emory University (AG025688) | Patient-Centered Outcomes Research Institute (CER-1306-01897) | National Institute on Aging (P30AG19610)

Authors: Andrea V. Cuc, Dona E.C. Locke, Noah Duncan, Julie A. Fields, Charlene Hoffman Snyder, Sherrie Hanna, Angela Lunde, Glenn E. Smith, Melanie Chandler

Preventive strategies to reduce depressive symptoms in overweight and obese young adults

Journal Article published Oct 2015 in Archives of Psychiatric Nursing volume 29 issue 5 on pages 258 to 264

Research funded by National Institute of Nursing Research (K01NR012779) | Alzheimer's Disease Research Center, Emory University | Atlanta Clinical and Translational Science Institute (UL1 RR025008)

Authors: EunSeok Cha, Betty J. Braxter, Kevin H. Kim, Heeyoung Lee, Margeaux K. Akazawa, Molly S. Talman, Melissa D. Pinto, Melissa Spezia Faulkner

Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction

Journal Article published 2 Nov 2015 in Aging Cell volume 15 issue 1 on pages 100 to 110

Research funded by NIH/NIA (AG037000, AG043125) | Alzheimer's Disease Research Center, Emory University (AG033514) | UW Institute on Aging (AG000213) | UW Department of Nutritional Sciences (DK007665)

Authors: Stephen A. Martin, Tyler M. DeMuth, Karl N. Miller, Thomas D. Pugh, Michael A. Polewski, Ricki J. Colman, Kevin W. Eliceiri, Timothy Mark Beasley, Sterling C. Johnson, Rozalyn M. Anderson

Evidence for brain glucose dysregulation in Alzheimer's disease

Journal Article published Mar 2018 in Alzheimer's & Dementia volume 14 issue 3 on pages 318 to 329

Research funded by Accelerating Medicine Partnership (U01AG046161-02) | NINDS Emory Neuroscience Core (P30NS055077) | Alzheimer's Disease Research Center, Emory University (P50AG025688)

Authors: Yang An, Vijay R. Varma, Sudhir Varma, Ramon Casanova, Eric Dammer, Olga Pletnikova, Chee W. Chia, Josephine M. Egan, Luigi Ferrucci, Juan Troncoso, Allan I. Levey, James Lah, Nicholas T. Seyfried, Cristina Legido-Quigley, Richard O'Brien, Madhav Thambisetty

Proton Pump Inhibitors and Risk of Mild Cognitive Impairment and Dementia

Journal Article published 7 Jun 2017 in Journal of the American Geriatrics Society volume 65 issue 9 on pages 1969 to 1974

Research funded by Alzheimer's Disease Research Center, Emory University (5 P50 AG025688) | NIH-NIA (U01 AG016976) | National Institute on Aging (P30 AG019610, P30 AG013846, P50 AG008702, P50 AG025688, P50 AG047266, P30 AG010133, P50 AG005146, P50 AG005134, P50 AG016574, P50 AG005138, P30 AG008051, P30 AG013854, P30 AG008017, P30 AG010161, P50 AG047366, P30 AG010129, P50 AG016573, P50 AG016570, P50 AG005131, P50 AG023501, P30 AG035982, P30 AG028383, P30 AG010124, P50 AG005133, P50 AG005142, P30 AG012300, P50 AG005136, P50 AG033514, P50 AG005681, P50 AG047270)

Authors: Felicia C. Goldstein, Kyle Steenland, Liping Zhao, Whitney Wharton, Allan I. Levey, Ihab Hajjar

Multi-resolution statistical analysis of brain connectivity graphs in preclinical Alzheimer's disease

Journal Article published Sep 2015 in NeuroImage volume 118 on pages 103 to 117

Research funded by National Institutes of Health (R01 AG040396, R01 AG021155, P30 AG010129, K01 AG030514, R01 AG027161) | National Science Foundation (RI 1116584, 1252725) | National Institute on Aging (R01 AG037638) | Alzheimer's Disease Research Center, Emory University (AG033514) | Wisconsin Partnership Program | Institute for Clinical and Translational Research, University of Wisconsin, Madison (1UL1RR025011) | Waisman Center (HD003352-45)

Authors: Won Hwa Kim, Nagesh Adluru, Moo K. Chung, Ozioma C. Okonkwo, Sterling C. Johnson, Barbara B. Bendlin, Vikas Singh

A randomized, double-blind, placebo-controlled trial of resveratrol with glucose and malate (RGM) to slow the progression of Alzheimer's disease: A pilot study

Journal Article published 2018 in Alzheimer's & Dementia: Translational Research & Clinical Interventions volume 4 on pages 609 to 616

Research funded by Alzheimer's Association | Alzheimer's Disease Research Center, Emory University | U.S. Department of Veterans Affairs

Authors: Carolyn W. Zhu, Hillel Grossman, Judith Neugroschl, Susan Parker, Amanda Burden, Xiaodong Luo, Mary Sano

Diminished neural network dynamics in amnestic mild cognitive impairment

Journal Article published Aug 2018 in International Journal of Psychophysiology volume 130 on pages 63 to 72

Research funded by VA Merit (IRX001534) | SPiRE (IRX001381) | Career Development Award (B6366W) | National Institutes of Health | National Institute on Aging (5P30AG053760) | Alzheimer's Disease Research Center, Emory University (2P50AG025688)

Authors: Einat K. Brenner, Benjamin M. Hampstead, Emily C. Grossner, Rachel A. Bernier, Nicholas Gilbert, K. Sathian, Frank G. Hillary

Understanding the ridesharing needs of older adults

Journal Article published Oct 2018 in Travel Behaviour and Society volume 13 on pages 155 to 164

Research funded by Agency for Healthcare Research and Quality (5P50HS019917-04) | Alzheimer's Disease Research Center, Emory University | CHESS | University of Wisconsin-Madison

Authors: Rashmi P. Payyanadan, John D. Lee

Association between polychlorinated biphenyls and Parkinson's disease neuropathology

Journal Article published Oct 2012 in NeuroToxicology volume 33 issue 5 on pages 1298 to 1304

Research funded by National Institutes of Health Mentored Quantitative Research Development Award (K25 ES014659) | Emory Parkinson's disease Collaborative Environmental Research Center (PD-CERC) (P01 ES016731) | National Research Service Fellowship Award (F30 ES014141) | Alzheimer's Disease Research Center, Emory University (P50 AG025688) | Emory Neuroscience NINDS Core Facilities (30 NS055077)

Authors: Jaime M. Hatcher-Martin, Marla Gearing, Kyle Steenland, Allan I. Levey, Gary W. Miller, Kurt D. Pennell