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Multiple prenatal ultrasound scans and ocular development: 20-year follow-up of a randomized controlled trial

Journal Article published Aug 2014 in Ultrasound in Obstetrics & Gynecology volume 44 issue 2 on pages 166 to 170

Research funded by The Ophthalmic Research Institute of Australia | National Health and Medical Research Council (1021105) | Alcon Research Institute | Australian Foundation for the Prevention of Blindness

Authors: H. Forward, S. Yazar, A. W. Hewitt, J. Khan, J. A. Mountain, K. Pesudovs, C. M. McKnight, A. X. Tan, C. E. Pennell, D. A. Mackey, J. P. Newnham

Innovative alternatives in the surgical management of glaucoma with cataract surgery

Journal Article published 16 Aug 2017 in Expert Review of Ophthalmology volume 12 issue 5 on pages 403 to 419

Research funded by Alcon Research Institute | Novartis

Authors: Tsontcho Ianchulev, Iqbal I. K. Ahmed, Robert L. Stamper, David F. Chang, Thomas W. Samuelson, Richard L. Lindstrom

Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain

Journal Article published 18 Jan 2018 in New England Journal of Medicine volume 378 issue 3 on pages 250 to 261

Research funded by Alcon Research Institute (14B065) | Swiss Cancer League (LSCC 2939-02-2012) | Canada Foundation for Innovation equipment grant | H2020 European Research Council | Canadian Institutes of Health Research (MOP-119506) | Medicine by Design | American Heart Association (16GRNT31330023)

Authors: Sergey I. Nikolaev, Sandra Vetiska, Ximena Bonilla, Emilie Boudreau, Suvi Jauhiainen, Behnam Rezai Jahromi, Nadiya Khyzha, Peter V. DiStefano, Santeri Suutarinen, Tim-Rasmus Kiehl, Vitor Mendes Pereira, Alexander M. Herman, Timo Krings, Hugo Andrade-Barazarte, Takyee Tung, Taufik Valiante, Gelareh Zadeh, Mike Tymianski, Tuomas Rauramaa, Seppo Ylä-Herttuala, Joshua D. Wythe, Stylianos E. Antonarakis, Juhana Frösen, Jason E. Fish, Ivan Radovanovic

Cellular strategies for retinal repair by photoreceptor replacement

Journal Article published May 2015 in Progress in Retinal and Eye Research volume 46 on pages 31 to 66

Research funded by Medical Research Council (mr/j004553/1) | Biotechnology and Biological Sciences Research Council (BB/1013636/1) | ERC (323147-STERD) | Fight for Sight (1448/1449) | Macula Vision Research Foundation | Moorfields Eye Charity | Alcon Research Institute | National Institute for Health Research (NIHR) Biomedical Research Centre | UCL Institute of Ophthalmology (BR2-007)

Authors: Sujatha A. Jayakody, Anai Gonzalez-Cordero, Robin R. Ali, Rachael A. Pearson

Caveolins and caveolae in ocular physiology and pathophysiology

Journal Article published Jan 2017 in Progress in Retinal and Eye Research volume 56 on pages 84 to 106

Research funded by National Institutes of Health (R01-EY019494, P30-EY021725, T32-EY023202) | BrightFocus Foundation (G2013092) | Alcon Research Institute

Authors: Xiaowu Gu, Alaina M. Reagan, Mark E. McClellan, Michael H. Elliott

Dual Energy X-Ray Absorptiometry Compared with Anthropometry in Relation to Cardio-Metabolic Risk Factors in a Young Adult Population: Is the ‘Gold Standard’ Tarnished?

Journal Article published 13 Sep 2016 in PLOS ONE volume 11 issue 9 on page e0162164

Research funded by Lions Eye Institute | Canadian Institutes of Health Research (MOP82893) | Australian Foundation for the Prevention of Blindness | Women and Infants Research Foundation, University of Western Australia | National Health and Medical Research Council | Faculty of Medicine, Dentistry and Health Sciences, University of Western Australia | Raine Medical Research Foundation | Curtin University of Technology | Alcon Research Institute | Telethon Institute for Child Health Research

Authors: Denise L. Demmer, Lawrence J. Beilin, Beth Hands, Sally Burrows, Craig E. Pennell, Stephen J. Lye, Jennifer A. Mountain, Trevor A. Mori

Editors: Xiao-Feng Yang

Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study

Journal Article published 26 Sep 2017 in Diabetes volume 66 issue 12 on pages 3130 to 3141

Research funded by Jackson State University (HHSN268201300049C, HHSN268201300050C) | National Institute on Aging (ZIAAG007380, R01AG023629) | Tougaloo College (HHSN268201300048C) | National Health and Medical Research Council (595918, 974159, 211069, 302068, 529923, 512423, 475604, 529912) | National Heart, Lung, and Blood Institute (HHSN268201200036C, HHSN268200800007C, N01HC55222, N01HC85079, N01HC85080, N01HC85081, N01HC85082, N01HC85083, N01HC85086, N01HC75150, U01HL080295,, U01HL130114, HL105756, HHSN268201500003I, N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168, N01-HC-95169, UL1-TR-000040, UL1-TR-001079, UL1-TR-001881, DK063491, N02-HL-64278) | Wellcome Trust (085475/B/08/Z, 085475/08/Z) | Biomedical Research Council (08/1/35/19/550, 09/1/35/19/616) | National Medical Research Council (0796/2003, 1176/2008, 1149/2008, STaR/0003/2008, 1249/2010, CG/SERI/2010, CIRG/1371/2013, CIRG/1417/2015, CSA/033/2012) | Academia Sinica (Biosignature Project)) | Massachusetts Lions Eye Research Fund | Alcon Research Institute (Young Investigator Award) | Research to Prevent Blindness (Career Development Grant, Special Scholar Award) | National Eye Institute (EY16335, EY22302, ZIAEY00401, N01-AG-1-2100) | American Diabetes Association (1-11-CT-51) | Harvard Catalyst (Faculty Fellowship Award) | University of Mississippi (HHSN268201300046C, HHSN268201300047C)

Authors: Lucia Sobrin, Yong He Chong, Qiao Fan, Alfred Gan, Lynn K. Stanwyck, Georgia Kaidonis, Jamie E. Craig, Jihye Kim, Wen-Ling Liao, Yu-Chuen Huang, Wen-Jane Lee, Yi-Jen Hung, Xiuqing Guo, Yang Hai, Eli Ipp, Samuela Pollack, Heather Hancock, Alkes Price, Alan Penman, Paul Mitchell, Gerald Liew, Albert V. Smith, Vilmundur Gudnason, Gavin Tan, Barbara E.K. Klein, Jane Kuo, Xiaohui Li, Mark W. Christiansen, Bruce M. Psaty, Kevin Sandow, Richard A. Jensen, Ronald Klein, Mary Frances Cotch, Jie Jin Wang, Yucheng Jia, Ching J. Chen, Yii-Der Ida Chen, Jerome I. Rotter, Fuu-Jen Tsai, Craig L. Hanis, Kathryn P. Burdon, Tien Yin Wong, Ching-Yu Cheng, Asian Genetic Epidemiology Network Consortium

Complete 360° circumferential gonioscopic optical coherence tomography imaging of the iridocorneal angle

Journal Article published 20 Mar 2015 in Biomedical Optics Express volume 6 issue 4 on page 1376

Research funded by Alcon Research Institute | Wallace H. Coulter Foundation

Authors: Ryan P. McNabb, Pratap Challa, Anthony N. Kuo, Joseph A. Izatt

Imaging retinal melanin: a review of current technologies

Journal Article published Dec 2018 in Journal of Biological Engineering volume 12 issue 1

Research funded by National Eye Institute (R01EY024969) | Alcon Research Institute (N/A) | Morgridge Institute for Research (N/A)

Authors: Maryse Lapierre-Landry, Joseph Carroll, Melissa C. Skala

Photothermal optical coherence tomography of indocyanine green in ex vivo eyes

Journal Article published 16 May 2018 in Optics Letters volume 43 issue 11 on page 2470

Research funded by National Institutes of Health (P30EY001931, R01 CA1857447, R01 CA205101, R01 CA211082) | Stand Up To Cancer (Sharp Award, SU2C-AACR-IG-08-16) | U.S. Department of Defense (W81XWH-13-1-0194) | National Science Foundation (CBET-1642287) | Mary Kay Foundation (067-16) | Alcon Research Institute

Authors: Maryse Lapierre-Landry, Thomas B. Connor, Joseph Carroll, Yuankai K. Tao, Melissa C. Skala

Gene Expression Profiling and PRAME Status Versus Tumor-Node-Metastasis Staging for Prognostication in Uveal Melanoma

Journal Article published Nov 2018 in American Journal of Ophthalmology volume 195 on pages 154 to 160

Research funded by National Cancer Institute | National Institutes of Health (P30EY014801) | Alcon Research Institute | Research to Prevent Blindness | Inc Senior Investigator Award | U.S. Department of Defense (W81XWH-13-1-0048) | Research to Prevent Blindness Unrestricted Grant

Authors: Louis Cai, Manuel Paez-Escamilla, Scott D. Walter, Bercin Tarlan, Christina L. Decatur, Barbara M. Perez, J.William Harbour

Top-down influence on the visual cortex of the blind during sensory substitution

Journal Article published Jan 2016 in NeuroImage volume 125 on pages 932 to 940

Research funded by Eye and Ear Foundation of Pittsburgh | U.S. Department of Defense (DM090217) | Postdoctoral Fellowship Program in Ocular Tissue Engineering and Regenerative Ophthalmology | University of Pittsburgh | National Institutes of Health (P30-EY008098, T32-EY017271) | Aging Institute Pilot Seed Grant | Alcon Research Institute | Louis J. Fox Center for Vision Restoration | Research to Prevent Blindness | Medical Center, University of Pittsburgh

Authors: Matthew C. Murphy, Amy C. Nau, Christopher Fisher, Seong-Gi Kim, Joel S. Schuman, Kevin C. Chan

Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections

Journal Article published Mar 2018 in Experimental Eye Research volume 168 on pages 69 to 76

Research funded by Vision Research Core | National Institutes of Health (P30 EY12576, P510D011107, K08 EY026101, P30 EY005722, K08 EY021142) | California National Primate Research Center | E. Matilda Ziegler Foundation for the Blind | Barr Foundation for Retinal Research | Alcon Research Institute | ARVO Foundation for Eye Research | School of Veterinary Medicine Endowment

Authors: Glenn Yiu, Zhe Wang, Christian Munevar, Eric Tieu, Bradley Shibata, Brittany Wong, David Cunefare, Sina Farsiu, Jeffrey Roberts, Sara M. Thomasy

Lubricous Hydrogel Surface Coatings on Polydimethylsiloxane (PDMS)

Journal Article published 19 Nov 2016 in Tribology Letters volume 65 issue 1

Research funded by Alcon Research Institute

Authors: Alexander Rudy, Cary Kuliasha, Juan Uruena, Jessica Rex, Kyle D. Schulze, Daniel Stewart, Thomas Angelini, W. G. Sawyer, Scott S. Perry

Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)

Journal Article published 18 Apr 2016 in Journal of Neuroinflammation volume 13 issue 1

Research funded by Deutsche Forschungsgemeinschaft (WE 1259/19-1, WE 1259/19-2) | Alcon Research Institute (ARI Award 2007) | National Health and Medical Research Council (#1028444, #1073726)

Authors: Felix Grassmann, Stuart Cantsilieris, Anja-Sabrina Schulz-Kuhnt, Stefan J. White, Andrea J Richardson, Alex W Hewitt, Brendan J. Vote, Denise Schmied, Robyn H Guymer, Bernhard H.F. Weber, Paul N. Baird

SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth

Journal Article published 22 Sep 2015 in Science Signaling volume 8 issue 395 on pages ra94 to ra94

Research funded by Seventh Framework Programme (305485 PREVENT-ROP) | Lowy Family Foundation | Boston Children's Hospital | Foundation Fighting Blindness | Deutsche Ophthalmologische Gesellschaft | Mass Lions Eye Research Fund Inc. | Deutsche Forschungsgemeinschaft (STA 1102/5-1) | Alcon Research Institute | BrightFocus Foundation | National Eye Institute (EY022275, EY017017, P01 HD18655, R01 EY024963) | Canadian Child Health Clinician Scientist Program | Fonds de Recherche du Québec - Santé | Burroughs Wellcome Fund

Authors: Ye Sun, Meihua Ju, Zhiqiang Lin, Thomas W. Fredrick, Lucy P. Evans, Katherine T. Tian, Nicholas J. Saba, Peyton C. Morss, William T. Pu, Jing Chen, Andreas Stahl, Jean-Sébastien Joyal, Lois E. H. Smith

The Eyes Have it

Journal Article published 23 Aug 2018 in Arthritis & Rheumatology volume 70 issue 10 on pages 1533 to 1543

Research funded by Spondylitis Association of America | Stan and Madelle Rosenfeld Family Trust | National Institute for Health Research Biomedical Research Centre (Moorfields Eye Hospital) | Alcon Research Institute | Research to Prevent Blindness | National Eye Institute (R01-EY-026572) | William and Mary Bauman Foundation | Rheumatology Research Foundation | National Health Service Foundation Trust | University College London

Authors: James T. Rosenbaum, Andrew D. Dick

Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging

Journal Article published Apr 2016 in Neurobiology of Aging volume 40 on pages 110 to 119

Research funded by Department of Health's National Institute for Health Research | Moorfields Biomedical Research Centre | Alcon Research Institute

Authors: Scott J. Robbie, Anastasios Georgiadis, Susie E. Barker, Yanai Duran, Alexander J. Smith, Robin R. Ali, Ulrich F.O. Luhmann, James W. Bainbridge

Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration

Journal Article published Jun 2017 in Stem Cell Reports volume 8 issue 6 on pages 1659 to 1674

Research funded by Otto van der Wyck | A Star Singapore | Moorfields Eye Charity | H2020 European Research Council (ERC-2012-ADG_20120314) | Wellcome Trust (WT083345MA) | Great Ormond Street Hospital for Children | Fight for Sight (1448/1449) | Medical Research Council (MR/J004553/1, MR/M007871/1, MR/L012758/1) | Macula Vision Research Foundation | The Miller's Trust | Alcon Research Institute | NIHR Biomedical Research Center

Authors: Kamil Kruczek, Anai Gonzalez-Cordero, Debbie Goh, Arifa Naeem, Mindaugas Jonikas, Samuel J.I. Blackford, Magdalena Kloc, Yanai Duran, Anastasios Georgiadis, Robert D. Sampson, Ryea N. Maswood, Alexander J. Smith, Sarah Decembrini, Yvan Arsenijevic, Jane C. Sowden, Rachael A. Pearson, Emma L. West, Robin R. Ali

Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors

Journal Article published Sep 2017 in Stem Cell Reports volume 9 issue 3 on pages 820 to 837

Research funded by Moorfields Eye Charity | H2020 European Research Council (ERC-2012-ADG_20120314) | Wellcome Trust (GR082557, 099173/Z/12/Z) | Joint MRC (G0700089) | Fight for Sight (1448/1449) | Medical Research Council (MR/J004553/1, MR/M007871/1, MR/L012758/1) | Macula Vision Research Foundation | The Miller's Trust | Alcon Research Institute | Mr Otto van der Wyck | Moorfields Eye Hospital

Authors: Anai Gonzalez-Cordero, Kamil Kruczek, Arifa Naeem, Milan Fernando, Magdalena Kloc, Joana Ribeiro, Debbie Goh, Yanai Duran, Samuel J.I. Blackford, Laura Abelleira-Hervas, Robert D. Sampson, Ian O. Shum, Matthew J. Branch, Peter J. Gardner, Jane C. Sowden, James W.B. Bainbridge, Alexander J. Smith, Emma L. West, Rachael A. Pearson, Robin R. Ali