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TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy

Journal Article published Mar 2017 in Immunological Reviews volume 276 issue 1 on pages 165 to 177

Research funded by National Institutes of Health | National Institute of Allergy and Infectious Diseases (R01 AI089824) | Alliance for Lupus Research | Yale Melanoma SPORE | Yale Cancer Center | Yale Immunobiology Department | Richard K. Gershon Fellowship | HHMI Faculty Scholar Award.

Authors: Yemsratch T. Akalu, Carla V. Rothlin, Sourav Ghosh

Inhibition of Cyclic GMP-AMP Synthase Using a Novel Antimalarial Drug Derivative in Trex1 -Deficient Mice

Journal Article published 14 Sep 2018 in Arthritis & Rheumatology volume 70 issue 11 on pages 1807 to 1819

Research funded by Life Sciences Discovery Fund (15834191) | Alliance for Lupus Research | University of Washington | Pew Charitable Trusts | Nanfang Hospital (2014C008) | Natural Science Foundation of Guangdong Province (2017A030313508)

Authors: Jie An, Joshua J. Woodward, Weinan Lai, Mark Minie, Xizhang Sun, Lena Tanaka, Jessica M. Snyder, Tomikazu Sasaki, Keith B. Elkon

Editorial: Epigenetics of B Cells and Antibody Responses

Journal Article published 11 Jan 2016 in Frontiers in Immunology volume 6

Research funded by National Institutes of Health (AI079705, AI105813) | Alliance for Lupus Research (295955)

Authors: Hong Zan, Paolo Casali

The Future of B-cell Activating Factor Antagonists in the Treatment of Systemic Lupus Erythematosus

Journal Article published 2017 in Journal of Rheumatic Diseases volume 24 issue 2 on page 65

Research funded by Alliance for Lupus Research

Authors: William Stohl

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

Journal Article published 15 Feb 2016 in eLife volume 5

Research funded by Alliance for Lupus Research | Walter M. and Helen D. Bader Center | NIH Office of the Director (AR055503, AI045196, AR058959)

Authors: Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A Wise, John B Harley, Swapan K Nath, Judith A James, Chaim O Jacob, Betty P Tsao, Chandrashekhar Pasare, David R Karp, Quan Zhen Li, Patrick M Gaffney, Edward K Wakeland

Blockade of CD354 (TREM-1) Ameliorates Anti-GBM-Induced Nephritis

Journal Article published 15 Apr 2016 in Inflammation

Research funded by National Institutes of Health (DK081872, P50-AR055503) | Alliance for Lupus Research

Authors: Yong Du, Tianfu Wu, Xin J. Zhou, Laurie S. Davis, Chandra Mohan

Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full-Blown Lupus in NZM 2328 Mice

Journal Article published 5 Jul 2017 in Arthritis & Rheumatology volume 69 issue 8 on pages 1647 to 1660

Research funded by National Institutes of Health (R01-AR-057172) | Alliance for Lupus Research | Children's Discovery Institute at Washington University and St. Louis Children's Hospital

Authors: Chaim O. Jacob, Ning Yu, Dae-Goon Yoo, Lizet J. Perez-Zapata, Emilia Alina Barbu, Mariana J. Kaplan, Monica Purmalek, Jeanette T. Pingel, Rachel A. Idol, Mary C. Dinauer

Defining Biological Subsets in Systemic Lupus Erythematosus: Progress Toward Personalized Therapy

Journal Article published 25 Jan 2017 in Pharmaceutical Medicine volume 31 issue 2 on pages 81 to 88

Research funded by Lupus Research Institute | Conselho Nacional Pesquisa Desenvolvimento-Brasil (CNPq) (300447/2009-4 and 471343/2011-0 and 302205/2012-8 and 473328/2013-5) | National Institutes of Health (AR060861, AR057781, AR065964, AI071651) | CureJM Foundation | Alliance for Lupus Research | The Myositis Foundation | Fundação Apoio À Pesquisa Estado São Paulo-Brasil (FAPESP) (2008/02917-0 and 2009/06049-6 and 2009/15286-1) | Rheumatology Research Foundation | Mayo Foundation for Medical Education and Research | Lupus Foundation of Minnesota

Authors: Nailú Angélica Sinicato, Mariana Postal, Simone Appenzeller, Timothy B. Niewold

The Use of Poly-L-Lysine as a Capture Agent to Enhance the Detection of Antinuclear Antibodies by ELISA

Journal Article published 9 Sep 2016 in PLOS ONE volume 11 issue 9 on page e0161818

Research funded by U.S. Department of Veterans Affairs | Alliance for Lupus Research | National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR 43727)

Authors: Nancy A. Stearns, Shuxia Zhou, Michelle Petri, Steven R. Binder, David S. Pisetsky

Editors: Johan van der Vlag

Transfer of antigen from human B cells to dendritic cells

Journal Article published Mar 2014 in Molecular Immunology volume 58 issue 1 on pages 56 to 65

Research funded by National Institutes of Health (AI-48120, AR-41032) | Alliance for Lupus Research

Authors: Bohdan P. Harvey, Maurice T. Raycroft, Timothy E. Quan, Benjamin J. Rudenga, Robert M. Roman, Joe Craft, Mark J. Mamula