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Harvard Stem Cell Institute
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Enhancing engineered vascular networks in vitro and in vivo: The effects of IGF1 on vascular development and durability

Journal Article published 7 Nov 2017 in Cell Proliferation volume 51 issue 1 on page e12387

Research funded by Stanley H. Durwood Foundation | Harvard Stem Cell Institute | Charité – Universitätsmedizin Berlin | Biomedical Sciences Exchange Program of the International Academy of Life Sciences

Authors: Claudia C. Friedrich, Yunfeng Lin, Alexander Krannich, Yinan Wu, Joseph P. Vacanti, Craig M. Neville

HCELL Expression on Murine MSC Licenses Pancreatotropism and Confers Durable Reversal of Autoimmune Diabetes in NOD Mice

Journal Article published 23 Apr 2015 in STEM CELLS volume 33 issue 5 on pages 1523 to 1531

Research funded by Edward and Dana Slatkin Research Fund | National Heart, Lung, and Blood Institute (PO1 HL107146, RO1 HL60528, RO1 HL73714) | American Diabetes Association Basic Science (110151) | Harvard Stem Cell Institute (109210) | postdoctoral fellowship

Authors: Reza Abdi, Robert Moore, Shinobu Sakai, Conor B. Donnelly, Marwan Mounayar, Robert Sackstein

Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation

Journal Article published Dec 2018 in Molecular Metabolism volume 18 on pages 153 to 163

Research funded by Juvenile Diabetes Research Foundation United States of America (3-APF-2017-393-A-N) | Portuguese Foundation for Science and Technology – FCT (SFRH/BD/51699/2011) | Harvard Stem Cell Institute (R01 DK67536) | National Institutes of Health (R01 DK103215, UC4 DK104167, DP3 DK110844) | Y-HT (R01DK077097, R01DK102898) | American Diabetes Association Fellowship (#1-18-PDF-169)

Authors: Manoj K. Gupta, Dario F. De Jesus, Sevim Kahraman, Ivan A. Valdez, Farnaz Shamsi, Lian Yi, Adam C. Swensen, Yu-Hua Tseng, Wei-Jun Qian, Rohit N. Kulkarni

Building blocks of the cerebral cortex: from development to the dish

Journal Article published 29 Apr 2015 in Wiley Interdisciplinary Reviews: Developmental Biology volume 4 issue 5 on pages 529 to 544

Research funded by National Institutes of Health | Harvard Stem Cell Institute | Target ALS | New York Stem Cell Foundation | National Institute of General Medical Sciences (T32GM007753)

Authors: James Harris, Giulio Srubek Tomassy, Paola Arlotta

Engineering Escherichia coli into a Protein Delivery System for Mammalian Cells

Journal Article published 24 Apr 2015 in ACS Synthetic Biology volume 4 issue 5 on pages 644 to 654

Research funded by Howard Hughes Medical Institute | NIH Office of the Director (DP2 OD004345) | National Institute of Diabetes and Digestive and Kidney Diseases (DK036836) | National Institute of Allergy and Infectious Diseases (AI064285) | Harvard Stem Cell Institute | National Institute of General Medical Sciences (GM094941)

Authors: Analise Z. Reeves, William E. Spears, Juan Du, Kah Yong Tan, Amy J. Wagers, Cammie F. Lesser

Adapted MS/MSALL Shotgun Lipidomics Approach for Analysis of Cardiolipin Molecular Species

Journal Article published Jan 2018 in Lipids volume 53 issue 1 on pages 133 to 142

Research funded by National Institutes of Health (R01DK077097, F32DK102320, T32DK007260) | American Diabetes Foundation | Harvard Stem Cell Institute | BERG, LLC

Authors: Fei Gao, Justice McDaniel, Emily Y. Chen, Hannah E. Rockwell, Cindy Nguyen, Matthew D. Lynes, Yu-Hua Tseng, Rangaprasad Sarangarajan, Niven R. Narain, Michael A. Kiebish

Repairing the corneal epithelium using limbal stem cells or alternative cell-based therapies

Journal Article published 6 Mar 2018 in Expert Opinion on Biological Therapy volume 18 issue 5 on pages 505 to 513

Research funded by National Eye Institute (RO1EY025794-01A1) | National Institutes of Health (P30EY003790) | Rehabilitation Research and Development Service (1I01RX000989) | Harvard Stem Cell Institute | Kanae Foundation for the Promotion of Medical Science

Authors: Yuzuru Sasamoto, Bruce R. Ksander, Markus H. Frank, Natasha Y. Frank

Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1

Journal Article published Aug 2017 in Stem Cell Reports volume 9 issue 2 on pages 667 to 680

Research funded by Harvard Stem Cell Institute (DP-0065-10-00) | GlaxoSmithKline

Authors: Pratibha Tripathi, Natalia Rodriguez-Muela, Joseph R. Klim, A. Sophie de Boer, Sahil Agrawal, Jackson Sandoe, Claudia S. Lopes, Karolyn Sassi Ogliari, Luis A. Williams, Matthew Shear, Lee L. Rubin, Kevin Eggan, Qiao Zhou

A synergistic DNA logic predicts genome-wide chromatin accessibility

Journal Article published 25 Jul 2016 in Genome Research volume 26 issue 10 on pages 1430 to 1440

Research funded by National Institutes of Health (5UL1DE019581, RL1DE019021, 1K01DK101684-01, 1U01HG007037, 5P01NS055923) | Harvard Stem Cell Institute | Human Frontier Science Program

Authors: Tatsunori Hashimoto, Richard I. Sherwood, Daniel D. Kang, Nisha Rajagopal, Amira A. Barkal, Haoyang Zeng, Bart J.M. Emons, Sharanya Srinivasan, Tommi Jaakkola, David K. Gifford

Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα

Journal Article published 3 Aug 2018 in Molecules volume 23 issue 8 on page 1938

Research funded by Center for Strategic Scientific Initiatives, National Cancer Institute (R21CA178301, R01CA169259) | Conquer Cancer Foundation (RSG-13-047) | Harvard Stem Cell Institute (DP-0110-12-00) | Ministry of Education - Singapore (Research Centres of Excellence initiative) | National Institute for Interdisciplinary Science and Technology (CSC0301)

Authors: Radhakrishnan Sridhar, Hisashi Takei, Riyaz Syed, Ikei Kobayashi, Liu Hui, Ahmed Kamal, Daniel Tenen, Susumu Kobayashi