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DFG-out Mode of Inhibition by an Irreversible Type-1 Inhibitor Capable of Overcoming Gate-Keeper Mutations in FGF Receptors

Journal Article published 27 Oct 2014 in ACS Chemical Biology volume 10 issue 1 on pages 299 to 309

Research funded by National Cancer Institute (CA016087, CA130876-05) | National Institute of Dental and Craniofacial Research (DE13686) | National Natural Science Foundation of China (31270789, 81102486, 81273421) | Dana-Farber/Harvard Cancer Center

Authors: Zhifeng Huang, Li Tan, Huiyan Wang, Yang Liu, Steven Blais, Jingjing Deng, Thomas A. Neubert, Nathanael S. Gray, Xiaokun Li, Moosa Mohammadi

Stitched α-Helical Peptides via Bis Ring-Closing Metathesis

Journal Article published 21 Aug 2014 in Journal of the American Chemical Society volume 136 issue 35 on pages 12314 to 12322

Research funded by National Research Foundation of Korea (2012R1A2A01004687) | Dana-Farber/Harvard Cancer Center

Authors: Gerard J. Hilinski, Young-Woo Kim, Jooyeon Hong, Peter S. Kutchukian, Charisse M. Crenshaw, Shaunna S. Berkovitch, Andrew Chang, Sihyun Ham, Gregory L. Verdine

Quercetin modulates keratoconus metabolismin vitro

Journal Article published Jul 2015 in Cell Biochemistry and Function volume 33 issue 5 on pages 341 to 350

Research funded by National Eye Institute (R01EY023568, R01EY020886, T32EY023202, P30EY021725) | Dana-Farber/Harvard Cancer Center (P30CA006516) | National Cancer Institute (P01CA120964)

Authors: Tina B McKay, Akhee Sarker-Nag, Desiree' Lyon, John M Asara, Dimitrios Karamichos

Tumor PDCD1LG2 (PD-L2) Expression and the Lymphocytic Reaction to Colorectal Cancer

Journal Article published 16 Oct 2017 in Cancer Immunology Research volume 5 issue 11 on pages 1046 to 1055

Research funded by National Institutes of Health (P01 CA87969, UM1 CA186107, P01 CA55075, UM1 CA167552, P50 CA127003, R01 CA137178, R01 CA151993, R35 CA197735, K07 CA190673) | Dana-Farber/Harvard Cancer Center (K07 CA190673)

Authors: Yohei Masugi, Reiko Nishihara, Tsuyoshi Hamada, Mingyang Song, Annacarolina da Silva, Keisuke Kosumi, Mancang Gu, Yan Shi, Wanwan Li, Li Liu, Daniel Nevo, Kentaro Inamura, Yin Cao, Xiaoyun Liao, Katsuhiko Nosho, Andrew T. Chan, Marios Giannakis, Adam J. Bass, F. Stephen Hodi, Gordon J. Freeman, Scott J. Rodig, Charles S. Fuchs, Zhi Rong Qian, Jonathan A. Nowak, Shuji Ogino

MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome

Journal Article published Jun 2017 in The American Journal of Human Genetics volume 100 issue 6 on pages 843 to 853

Research funded by Dana-Farber/Harvard Cancer Center (5 P30 CA06516) | Howard Hughes Medical Institute | Houston Endowment | NSF (DMS 1263932) | Huffington Foundation | National Institute of Neurological Disorders and Stroke (1U54NS093793-01) | Pediatric Neurology Basic Neuroscience Research Track | Texas Children's Hospital | Baylor College of Medicine Medical Scientist Training Program | NIH/ORIP (1R24 OD022005-01) | NIH NIGMS (R01 GM067761, NIGMS R01 GM084947) | Cancer Prevention and Research Institute of Texas (RP170387) | T T Chao Family Foundation | Belfer Foundation | Simons Foundation (#368479) | Alzheimer's Association | NIH (3U54NS093793-02S1, R01 GM120033, R24 RR032668, R24 OD021997, U01HG007709)

Authors: Julia Wang, Rami Al-Ouran, Yanhui Hu, Seon-Young Kim, Ying-Wooi Wan, Michael F. Wangler, Shinya Yamamoto, Hsiao-Tuan Chao, Aram Comjean, Stephanie E. Mohr, Norbert Perrimon, Zhandong Liu, Hugo J. Bellen, Christopher J. Adams, David R. Adams, Mercedes E. Alejandro, Patrick Allard, Euan A. Ashley, Mashid S. Azamian, Carlos A. Bacino, Ashok Balasubramanyam, Hayk Barseghyan, Alan H. Beggs, Hugo J. Bellen, Jonathan A. Bernstein, Anna Bican, David P. Bick, Camille L. Birch, Braden E. Boone, Lauren C. Briere, Donna M. Brown, Matthew Brush, Elizabeth A. Burke, Lindsay C. Burrage, Katherine R. Chao, Gary D. Clark, Joy D. Cogan, Cynthia M. Cooper, William J. Craigen, Mariska Davids, Jyoti G. Dayal, Esteban C. Dell’Angelica, Shweta U. Dhar, Katrina M. Dipple, Laurel A. Donnell-Fink, Naghmeh Dorrani, Daniel C. Dorset, David D. Draper, Annika M. Dries, David J. Eckstein, Lisa T. Emrick, Christine M. Eng, Cecilia Esteves, Tyra Estwick, Paul G. Fisher, Trevor S. Frisby, Kate Frost, William A. Gahl, Valerie Gartner, Rena A. Godfrey, Mitchell Goheen, Gretchen A. Golas, David B. Goldstein, Mary G. Gordon, Sarah E. Gould, Jean-Philippe F. Gourdine, Brett H. Graham, Catherine A. Groden, Andrea L. Gropman, Mary E. Hackbarth, Melissa Haendel, Rizwan Hamid, Neil A. Hanchard, Lori H. Handley, Isabel Hardee, Matthew R. Herzog, Ingrid A. Holm, Ellen M. Howerton, Howard J. Jacob, Mahim Jain, Yong-hui Jiang, Jean M. Johnston, Angela L. Jones, Alanna E. Koehler, David M. Koeller, Isaac S. Kohane, Jennefer N. Kohler, Donna M. Krasnewich, Elizabeth L. Krieg, Joel B. Krier, Jennifer E. Kyle, Seema R. Lalani, Lea Latham, Yvonne L. Latour, C. Christopher Lau, Jozef Lazar, Brendan H. Lee, Hane Lee, Paul R. Lee, Shawn E. Levy, Denise J. Levy, Richard A. Lewis, Adam P. Liebendorfer, Sharyn A. Lincoln, Carson R. Loomis, Joseph Loscalzo, Richard L. Maas, Ellen F. Macnamara, Calum A. MacRae, Valerie V. Maduro, May Christine V. Malicdan, Laura A. Mamounas, Teri A. Manolio, Thomas C. Markello, Paul Mazur, Alexandra J. McCarty, Allyn McConkie-Rosell, Alexa T. McCray, Thomas O. Metz, Matthew Might, Paolo M. Moretti, John J. Mulvihill, Jennifer L. Murphy, Donna M. Muzny, Michele E. Nehrebecky, Stan F. Nelson, J. Scott Newberry, John H. Newman, Sarah K. Nicholas, Donna Novacic, Jordan S. Orange, J. Carl Pallais, Christina G.S. Palmer, Jeanette C. Papp, Loren D.M. Pena, John A. Phillips, Jennifer E. Posey, John H. Postlethwait, Lorraine Potocki, Barbara N. Pusey, Rachel B. Ramoni, Amy K. Robertson, Lance H. Rodan, Jill A. Rosenfeld, Sarah Sadozai, Katherine E. Schaffer, Kelly Schoch, Molly C. Schroeder, Daryl A. Scott, Prashant Sharma, Vandana Shashi, Edwin K. Silverman, Janet S. Sinsheimer, Ariane G. Soldatos, Rebecca C. Spillmann, Kimberly Splinter, Joan M. Stoler, Nicholas Stong, Kimberly A. Strong, Jennifer A. Sullivan, David A. Sweetser, Sara P. Thomas, Cynthia J. Tifft, Nathanial J. Tolman, Camilo Toro, Alyssa A. Tran, Zaheer M. Valivullah, Eric Vilain, Daryl M. Waggott, Colleen E. Wahl, Nicole M. Walley, Chris A. Walsh, Michael F. Wangler, Mike Warburton, Patricia A. Ward, Katrina M. Waters, Bobbie-Jo M. Webb-Robertson, Alec A. Weech, Monte Westerfield, Matthew T. Wheeler, Anastasia L. Wise, Lynne A. Wolfe, Elizabeth A. Worthey, Shinya Yamamoto, Yaping Yang, Guoyun Yu, Patricia A. Zornio

A phase 2 trial of abiraterone acetate without glucocorticoids for men with metastatic castration-resistant prostate cancer

Journal Article published 14 Nov 2018 in Cancer

Research funded by DF/HCC Prostate Cancer SPORE (NCI P50 CA090381) | Fairweather Family Fund | Janssen Pharmaceuticals | Fat Boys Slim Sisters Fund | Dana-Farber Cancer Institute | Prostate Cancer Foundation (142016;) | Dana-Farber/Harvard Cancer Center

Authors: Rana R. McKay, Lillian Werner, Susanna J. Jacobus, Alexandra Jones, Elahe A. Mostaghel, Brett T. Marck, Atish D. Choudhury, Mark M. Pomerantz, Christopher J. Sweeney, Susan F. Slovin, Michael J. Morris, Philip W. Kantoff, Mary-Ellen Taplin

Using narrative intervention for HPV vaccine behavior change among Khmer mothers and daughters: A pilot RCT to examine feasibility, acceptability, and preliminary effectiveness

Journal Article published Apr 2018 in Applied Nursing Research volume 40 on pages 51 to 60

Research funded by University of Massachusetts Boston | Dana-Farber/Harvard Cancer Center

Authors: Haeok Lee, Minjin Kim, Mary E. Cooley, Peter Nien-chu Kiang, Deogwoon Kim, Shirley Tang, Ling Shi, Linda Thiem, Penhsamnang Kan, Sonith Peou, Chhan Touch, Phala Chea, Jeroan Allison

SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b

Journal Article published Jun 2016 in Cell volume 165 issue 6 on pages 1401 to 1415

Research funded by National Institutes of Health (CA175727-01, R21CA198109-01, P50CA1270003, P01 CA117969-07, R01 CA133557-05) | National Pancreas Foundation | Linda J. Verville Cancer Research Foundation | National Cancer Institute (1K08CA194268-01) | Dana-Farber/Harvard Cancer Center (P50CA127003) | U.S. Department of Defense

Authors: Sita Kugel, Carlos Sebastián, Julien Fitamant, Kenneth N. Ross, Supriya K. Saha, Esha Jain, Adrianne Gladden, Kshitij S. Arora, Yasutaka Kato, Miguel N. Rivera, Sridhar Ramaswamy, Ruslan I. Sadreyev, Alon Goren, Vikram Deshpande, Nabeel Bardeesy, Raul Mostoslavsky

Smoking and Risk of Colorectal Cancer Sub-Classified by Tumor-Infiltrating T Cells

Journal Article published 11 Oct 2018 in JNCI: Journal of the National Cancer Institute volume 111 issue 1 on pages 42 to 51

Research funded by Japan Society for the Promotion of Science | Dana-Farber/Harvard Cancer Center | Project P Fund | National Research Foundation of Korea (NRF-2018R1C1B6008822, NRF-2018R1A4A1022589) | Canadian Breast Cancer Research Alliance | The Friends of the Dana-Farber Cancer Institute | Huazhong University of Science and Technology | Bennett Family Fund | National Institutes of Health (P01 CA87969, UM1 CA186107, P01 CA55075, UM1 CA167552, U01 CA167552, P50 CA127003, R01 CA118553, R01 CA169141, R01 CA137178, K24 DK098311, R35 CA197735, R01 CA151993, K07 CA190673, K07 CA188126) | China Scholarship Council | Stand Up To Cancer | Mitsukoshi Health and Welfare Foundation

Authors: Tsuyoshi Hamada, Jonathan A Nowak, Yohei Masugi, David A Drew, Mingyang Song, Yin Cao, Keisuke Kosumi, Kosuke Mima, Tyler S Twombly, Li Liu, Yan Shi, Annacarolina da Silva, Mancang Gu, Wanwan Li, Katsuhiko Nosho, NaNa Keum, Marios Giannakis, Jeffrey A Meyerhardt, Kana Wu, Molin Wang, Andrew T Chan, Edward L Giovannucci, Charles S Fuchs, Reiko Nishihara, Xuehong Zhang, Shuji Ogino

Development of the perceived barriers scale: a new instrument identifying barriers to career development and employment for young adult survivors of pediatric CNS tumors

Journal Article published 24 Oct 2018 in Journal of Cancer Survivorship

Research funded by Dana-Farber/Harvard Cancer Center

Authors: David R. Strauser, Fong Chan, Elizabeth Fine, Kanako Iwanaga, Chelsea Greco, Cori Liptak