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Aeras Global Tuberculosis Vaccine Foundation
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Rhesus Macaques Are More Susceptible to Progressive Tuberculosis than Cynomolgus Macaques: a Quantitative Comparison

Journal Article published 25 Sep 2017 in Infection and Immunity volume 86 issue 2 on page e00505-17

Research funded by National Institutes of Health (HL110811, AI118195, AI094745, AI111871, AI111815, T32 AI0089443, T32 AI060525) | Aeras Global Tuberculosis Vaccine Foundation (no number) | Bill and Melinda Gates Foundation (no number)

Authors: Pauline Maiello, Robert M. DiFazio, Anthony M. Cadena, Mark A. Rodgers, Philana Ling Lin, Charles A. Scanga, JoAnne L. Flynn

Editors: Sabine Ehrt

Adjuvant-Associated Peripheral Blood mRNA Profiles and Kinetics Induced by the Adjuvanted Recombinant Protein Candidate Tuberculosis Vaccine M72/AS01 in Bacillus Calmette–Guérin-Vaccinated Adults

Journal Article published 26 Mar 2018 in Frontiers in Immunology volume 9

Research funded by Aeras Global Tuberculosis Vaccine Foundation

Authors: Robert A. van den Berg, Laurane De Mot, Geert Leroux-Roels, Viviane Bechtold, Frédéric Clement, Margherita Coccia, Erik Jongert, Thomas G. Evans, Paul Gillard, Robbert G. van der Most

Adenovirus type 35-vectored tuberculosis vaccine has an acceptable safety and tolerability profile in healthy, BCG-vaccinated, QuantiFERON ® -TB Gold (+) Kenyan adults without evidence of tuberculosis

Journal Article published May 2016 in Vaccine volume 34 issue 21 on pages 2430 to 2436

Research funded by Aeras Global Tuberculosis Vaccine Foundation

Authors: Douglas S. Walsh, Victorine Owira, Mark Polhemus, Lucas Otieno, Ben Andagalu, Bernhards Ogutu, John Waitumbi, Anthony Hawkridge, Barbara Shepherd, Maria Grazia Pau, Jerald Sadoff, Macaya Douoguih, J. Bruce McClain

STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection

Journal Article published May 2018 in Cell Reports volume 23 issue 5 on pages 1435 to 1447

Research funded by National Institutes of Health (T32 GM 7232-40, T32 AI 100829-4, 1R56AI091976-01) | National Science Foundation (DGE-1106400) | Aeras Global Tuberculosis Vaccine Foundation (036531-003) | Immunotherapeutics and Vaccine Research Initiative (042960-002)

Authors: Erik Van Dis, Kimberly M. Sogi, Chris S. Rae, Kelsey E. Sivick, Natalie H. Surh, Meredith L. Leong, David B. Kanne, Ken Metchette, Justin J. Leong, Jacob R. Bruml, Vivian Chen, Kartoosh Heydari, Nathalie Cadieux, Tom Evans, Sarah M. McWhirter, Thomas W. Dubensky, Daniel A. Portnoy, Sarah A. Stanley

Tuberculosis and Healthcare Workers in Underresourced Settings

Journal Article published 26 Apr 2016 in Clinical Infectious Diseases volume 62 issue suppl 3 on pages S229 to S230

Research funded by Aeras Global Tuberculosis Vaccine Foundation | National Institutes of Health | Bill and Melinda Gates Foundation

Authors: Thomas G. Evans, Linda-Gail Bekker

Using Data from Macaques To Predict Gamma Interferon Responses after Mycobacterium bovis BCG Vaccination in Humans: a Proof-of-Concept Study of Immunostimulation/Immunodynamic Modeling Methods

Journal Article published 11 Jan 2017 in Clinical and Vaccine Immunology volume 24 issue 3 on page e00525-16

Research funded by National Institute for Health Research | Aeras Global Tuberculosis Vaccine Foundation | Bill and Melinda Gates Foundation (OPP1084276/OPP1135288, OPP1110334, OPP1137034, OPP1160830) | Medical Research Council (MR/P002404/1)

Authors: Sophie J. Rhodes, Charlotte Sarfas, Gwenan M. Knight, Andrew White, Ansar A. Pathan, Helen McShane, Thomas G. Evans, Helen Fletcher, Sally Sharpe, Richard G. White

Editors: Helene F. Rosenberg

A blood RNA signature for tuberculosis disease risk: a prospective cohort study

Journal Article published Jun 2016 in The Lancet volume 387 issue 10035 on pages 2312 to 2322

Research funded by Seventh Framework Programme (280873, 115308, 643381) | Grand Challenges in Global Health (37772) | Fogarty International Center (5 D43 TW000231) | Columbia University | National Institutes of Health (RO1-AI087915) | Bill and Melinda Gates Foundation (OPP1021972, OPP1023483, 37772, 37885) | Department of Science and Technology, Republic of South Africa | Carnegie Corporation of New York | Aeras Global Tuberculosis Vaccine Foundation | Claude Leon Foundation

Authors: Daniel E Zak, Adam Penn-Nicholson, Thomas J Scriba, Ethan Thompson, Sara Suliman, Lynn M Amon, Hassan Mahomed, Mzwandile Erasmus, Wendy Whatney, Gregory D Hussey, Deborah Abrahams, Fazlin Kafaar, Tony Hawkridge, Suzanne Verver, E Jane Hughes, Martin Ota, Jayne Sutherland, Rawleigh Howe, Hazel M Dockrell, W Henry Boom, Bonnie Thiel, Tom H M Ottenhoff, Harriet Mayanja-Kizza, Amelia C Crampin, Katrina Downing, Mark Hatherill, Joe Valvo, Smitha Shankar, Shreemanta K Parida, Stefan H E Kaufmann, Gerhard Walzl, Alan Aderem, Willem A Hanekom

Considerations for biomarker-targeted intervention strategies for tuberculosis disease prevention

Journal Article published Mar 2018 in Tuberculosis volume 109 on pages 61 to 68

Research funded by Bill and Melinda Gates Foundation (OPP1021972, OPP1023483, OPP1116632, OPP1137034) | Center for Global Health | National Institutes of Health (RO1-AI087915) | South African Medical Research Council (TB/HIV/AIDS-01-2014) | Strategic Health Innovation Partnerships | Department of Science and Technology, Republic of South Africa | Aeras Global Tuberculosis Vaccine Foundation | BMGF GC 6-74 (37772) | BMGF GC 12 (37885)

Authors: Andrew Fiore-Gartland, Lindsay N. Carpp, Kogieleum Naidoo, Ethan Thompson, Daniel E. Zak, Steve Self, Gavin Churchyard, Gerhard Walzl, Adam Penn-Nicholson, Thomas J. Scriba, Mark Hatherill

Immunogenicity and Protective Efficacy of the DAR-901 Booster Vaccine in a Murine Model of Tuberculosis

Journal Article published 20 Dec 2016 in PLOS ONE volume 11 issue 12 on page e0168521

Research funded by Aeras Global Tuberculosis Vaccine Foundation | Dartmouth College

Authors: Timothy Lahey, Dominick Laddy, Krystal Hill, Jacqueline Schaeffer, Alison Hogg, James Keeble, Belinda Dagg, Mei Mei Ho, Robert D. Arbeit, C. Fordham von Reyn

Editors: Thomas Jens Scriba

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

Journal Article published 21 Jan 2016 in Science volume 351 issue 6274 on pages 714 to 720

Research funded by National Institutes of Health (P01-AI094417, R37-AI054292, R01-DE021291, R01-AI095113, R01-AI117802, R01-AI059457, U24-OD010850, P51-OD011092, P50-GM065794, HHSN272201100013C) | Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (UM1-AI100645-01) | Bill and Melinda Gates Foundation (OPP1108533, OPP1133649) | Aeras Global Tuberculosis Vaccine Foundation | Los Alamos National Laboratory

Authors: S. G. Hansen, H. L. Wu, B. J. Burwitz, C. M. Hughes, K. B. Hammond, A. B. Ventura, J. S. Reed, R. M. Gilbride, E. Ainslie, D. W. Morrow, J. C. Ford, A. N. Selseth, R. Pathak, D. Malouli, A. W. Legasse, M. K. Axthelm, J. A. Nelson, G. M. Gillespie, L. C. Walters, S. Brackenridge, H. R. Sharpe, C. A. Lopez, K. Fruh, B. T. Korber, A. J. McMichael, S. Gnanakaran, J. B. Sacha, L. J. Picker