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American Partnership for Eosinophilic Disorders
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Eosinophilic esophagitis phenotypes: Ready for prime time?

Journal Article published 4 May 2017 in Pediatric Allergy and Immunology volume 28 issue 4 on pages 312 to 319

Research funded by LaCache Chair in Gastrointestinal Allergic and Immunologic Diseases Stuart Starr Chair of Pediatrics | National Institute of Diabetes and Digestive and Kidney Diseases | Consortium for Gastrointestinal Eosinophilic Researchers (CEGIR) (U54 AI117804) | National Institute of Allergy and Infectious Diseases | American Partnership for Eosinophilic Disorders | National Institutes of Health (1K24DK100303) | National Center for Advancing Translational Sciences | CURED | Rare Diseases Clinical Research Network (RDCRN) | EFC | Office of Rare Diseases Research (ORDR) | The Children's Hospital of Philadelphia Eosinophilic Esophagitis Fund

Authors: Dan Atkins, Glenn T. Furuta, Chris A. Liacouras, Jonathan M. Spergel

Extracellular Microvesicle Production by Human Eosinophils Activated by “Inflammatory” Stimuli

Journal Article published 27 Oct 2016 in Frontiers in Cell and Developmental Biology volume 4

Research funded by National Institutes of Health (R37AI020241, R01AI022571, R01HL095699, K08HL116429) | Conselho Nacional de Desenvolvimento Científico e Tecnológico (477475/2013-2, 469995/2014-9, 311083/2014-5) | Fundação de Amparo à Pesquisa do Estado de Minas Gerais (CBB-APQ-02239-14) | American Partnership for Eosinophilic Disorders

Authors: Praveen Akuthota, Lívia A. S. Carmo, Kennedy Bonjour, Ryann O. Murphy, Thiago P. Silva, Juliana P. Gamalier, Kelsey L. Capron, John Tigges, Vasilis Toxavidis, Virginia Camacho, Ionita Ghiran, Shigeharu Ueki, Peter F. Weller, Rossana C. N. Melo

Airway eosinophil migration into lymph nodes in mice depends on leukotriene C4

Journal Article published 11 Jan 2017 in Allergy volume 72 issue 6 on pages 927 to 936

Research funded by National Institutes of Health (R37AI020241, R01AI051645, K08HL116429, U19AI095219, R21AI107425) | American Partnership for Eosinophilic Disorders

Authors: H.-B. Wang, P. Akuthota, Y. Kanaoka, P. F. Weller

Management of Esophageal Food Impaction Varies Among Gastroenterologists and Affects Identification of Eosinophilic Esophagitis

Journal Article published 20 Feb 2018 in Digestive Diseases and Sciences volume 63 issue 6 on pages 1428 to 1437

Research funded by National Institutes of Health (U54 AI117804) | American Partnership for Eosinophilic Disorders

Authors: Girish Hiremath, Michael F. Vaezi, Sandeep K. Gupta, Sari Acra, Evan S. Dellon

Resident intestinal eosinophils constitutively express antigen presentation markers and include two phenotypically distinct subsets of eosinophils

Journal Article published 21 Jan 2018 in Immunology volume 154 issue 2 on pages 298 to 308

Research funded by National Institutes of Health (3P30DK034854, R01AI121186, R37AI02024) | American Partnership for Eosinophilic Disorders | Harvard University

Authors: Jason J. Xenakis, Emily D. Howard, Kalmia M. Smith, Courtney L. Olbrich, Yanjun Huang, Dilanjan Anketell, Samuel Maldonado, Evangeline W. Cornwell, Lisa A. Spencer

Revisiting the NIH Taskforce on the Research needs of Eosinophil-Associated Diseases (RE-TREAD)

Journal Article published 19 Apr 2018 in Journal of Leukocyte Biology volume 104 issue 1 on pages 69 to 83

Research funded by Buckeye Career Center Foundation | U.S. Food and Drug Administration (R01FD004086) | National Institute of Allergy and Infectious Diseases (R37020241) | Israel Science Foundation (ISF 472/15) | National Institute for Health Research | National Fund for Scientific Research (F 5/4/150/4) | American Partnership for Eosinophilic Disorders (R01 AI072265, P01 HL107151, R01 AI105839) | National Institutes of Health (K08 HL116429, UG1 HL139117) | Campaign Urging Research for Eosinophilic Disease | Rare Disease Clinical Research Network | Sunshine Charitable Foundation

Authors: Paneez Khoury, Praveen Akuthota, Steven J. Ackerman, Joseph R. Arron, Bruce S. Bochner, Margaret H. Collins, Jean-Emmanuel Kahn, Patricia C. Fulkerson, Gerald J. Gleich, Rashmi Gopal-Srivastava, Elizabeth A. Jacobsen, Kristen M. Leiferman, Levi-Schaffer Francesca, Sameer K. Mathur, Michael Minnicozzi, Calman Prussin, Marc E. Rothenberg, Florence Roufosse, Kathleen Sable, Dagmar Simon, Hans-Uwe Simon, Lisa A. Spencer, Jonathan Steinfeld, Andrew J. Wardlaw, Michael E. Wechsler, Peter F. Weller, Amy D. Klion

Long-term assessment of esophageal remodeling in patients with pediatric eosinophilic esophagitis treated with topical corticosteroids

Journal Article published Jan 2016 in Journal of Allergy and Clinical Immunology volume 137 issue 1 on pages 147 to 156.e8

Research funded by National Institute of Diabetes and Digestive and Kidney Diseases | Hearst Foundations | CEGIRS (U54AI117804) | National Institute of Allergy and Infectious Diseases (AI 092135, AI 107779, AI 70535, AI 72115) | U.S. Department of Defense (FA100044) | ART | American Partnership for Eosinophilic Disorders | Rare Diseases Clinical Research Network | National Institutes of Health (ULRR031980) | CTSA (ULT1TR0001000) | National Center for Advancing Translational Sciences

Authors: Jessica Rajan, Robert O. Newbury, Arjun Anilkumar, Ranjan Dohil, David H. Broide, Seema S. Aceves

Individuals affected by eosinophilic gastrointestinal disorders have complex unmet needs and frequently experience unique barriers to care

Journal Article published Oct 2018 in Clinics and Research in Hepatology and Gastroenterology volume 42 issue 5 on pages 483 to 493

Research funded by American Partnership for Eosinophilic Disorders

Authors: Girish Hiremath, Ellyn Kodroff, Mary J. Strobel, Melissa Scott, Wendy Book, Cathy Reidy, Shay Kyle, Denise Mack, Kathleen Sable, Pablo Abonia, Jonathan Spergel, Sandeep K. Gupta, T. Glenn Furuta, Marc E. Rothenberg, Evan S. Dellon

Integrin αM activation and upregulation on esophageal eosinophils and periostin-mediated eosinophil survival in eosinophilic esophagitis

Journal Article published 6 Mar 2018 in Immunology and Cell Biology volume 96 issue 4 on pages 426 to 438

Research funded by American Partnership for Eosinophilic Disorders (HOPE Pilot Grant)

Authors: Praveen Vimalathas, Alexandra Farris, Dorothea Letner, Vikram Deshpande, Vijay Yajnik, Wayne Shreffler, John Garber

Immunology of the ancestral differences in eosinophilic esophagitis

Journal Article published Nov 2018 in Annals of Allergy, Asthma & Immunology

Research funded by Children's Hospital of Philadelphia (U54AI117804) | National Center for Advancing Translational Sciences | National Institute of Allergy and Infectious Diseases | National Institute of Diabetes and Digestive and Kidney Diseases | American Partnership for Eosinophilic Disorders | Campaign Urging Research for Eosinophilic Disease | EFC

Authors: Leah Kottyan, Jonathan M. Spergel, Antonella Cianferoni