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JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors

Journal Article published 29 Mar 2016 in Science Signaling volume 9 issue 421 on pages ra33 to ra33

Research funded by Nancy C. and Daniel P. Paduano Foundation | Uniting Against Lung Cancer | National Cancer Institute (R01CA 098234-01) | Susan G. Komen for the Cure | George Best Costacos Foundation | Beth C. Tortolani Foundation | Malcolm Hewitt Wiener Foundation | Sussman Family Fund | Physical Sciences-Oncology Centers (NCI-U54-CA143836) | New York State USBC Women's Bowling Association | Champalimaud Foundation | Children's Cancer and Blood Foundation | Hartwell Foundation | National Institutes of Health (U54 CA148967, R01 CA87637, P30 CA008748) | Charles and Marjorie Holloway Foundation | Pediatric Oncology Experimental Therapeutics Investigators Consortium | Stavros Niarchos Foundation | American Hellenic Educational Progressive Association Foundation | Manhasset Women's Coalition Against Breast Cancer | AstraZeneca | Manning Educational Foundation | Lerner Foundation | Mary Kay Foundation

Authors: Sizhi P. Gao, Qing Chang, Ninghui Mao, Laura A. Daly, Robert Vogel, Tyler Chan, Shu Hui Liu, Eirini Bournazou, Erez Schori, Haiying Zhang, Monica Red Brewer, William Pao, Luc Morris, Marc Ladanyi, Maria Arcila, Katia Manova-Todorova, Elisa de Stanchina, Larry Norton, Ross L. Levine, Gregoire Altan-Bonnet, David Solit, Michael Zinda, Dennis Huszar, David Lyden, Jacqueline F. Bromberg