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Genetic influence of plasma homocysteine on Alzheimer's disease

Journal Article published Feb 2018 in Neurobiology of Aging volume 62 on pages 243.e7 to 243.e14

Research funded by Neurotrack Technologies | National Institute of Biomedical Imaging and Bioengineering | Novartis Pharmaceuticals Corporation | Brain and Behavior Research Foundation | CereSpir, Inc | Canadian Institutes of Health Research | Alzheimer’s Research UK | Janssen Alzheimer Immunotherapy Research & Development, LLC | Pfizer | AbbVie | Bristol-Myers Squibb | Eisai | Ontario Mental Health Foundation | Erasmus Medisch Centrum | National Institute on Aging (P30AG10161, RF1AG15819, R01AG17917) | Euroimmun | CI | National Institute of Mental Health (R01MH099167, R01MH102324, 503176, 082604/2/07/Z, 01GI0102, 01GI0711, 01GI0420, R01 AG033193, NIA AG081220, N01–AG–12100, R01 HL105756, U01 AG032984, U24 AG021886, U01 AG016976, ADGC–10–196728, U01 AG024904, W81XWH-12-2-0012) | Erasmus Universiteit Rotterdam | U.S. Department of Defense | Lundbeckfonden | Lumosity | Bundesministerium für Bildung und Forschung | Competence Network Dementia (CND) | National Heart, Lung, and Blood Institute | Elan Pharmaceuticals, Inc | IXICO Ltd | National Institutes of Health | Piramal Imaging | Takeda Pharmaceutical Company | Wellcome Trust | Transition Therapeutics | Lille University Hospital | Servier | Alzheimer's Disease Neuroimaging Initiative | Genentech | Johnson and Johnson | Meso Scale Diagnostics | AGES | Medical Research Council (503480) | Institut National de la Santé et de la Recherche Médicale | GE Healthcare | Eli Lilly and Company | Centre for Addiction and Mental Health | Isabel Johnson Biomedical Postdoctoral Award | Biogen | Roche | Icelandic Heart Association | DISTALZ | Merck | Fujirebio Europe | Université de Lille 2 | Labex | Araclon Biotech | Institut Pasteur | Alzheimer's Drug Discovery Foundation | Alzheimer's Association | NeuroRx Research | BioClinica | French National Foundation on Alzheimer's disease and related disorders | Alzheimer Society Research Program

Authors: Tina Roostaei, Daniel Felsky, Arash Nazeri, Philip L. De Jager, Julie A. Schneider, David A. Bennett, Aristotle N. Voineskos

Buying time: a proof-of-concept randomized controlled trial to improve sleep quality and cognitive function among older adults with mild cognitive impairment

Journal Article published 17 Aug 2018 in Trials volume 19 issue 1

Research funded by Vancouver Coastal Health Research Institute (CA) (F16-01717) | Jack Brown and Family Alzheimer's Research Foundation | Alzheimer Society Research Program

Authors: Ryan S. Falck, Jennifer C. Davis, John R. Best, Linda C. Li, Patrick C. Y. Chan, Anne B. Wyrough, Glenn J. Landry, Teresa Liu-Ambrose

Visible light sensorless adaptive optics for retinal structure and fluorescence imaging

Journal Article published 15 Oct 2018 in Optics Letters volume 43 issue 20 on page 5162

Research funded by Michael Smith Foundation for Health Research | Alzheimer Society Research Program | National Research Foundation of Korea (NRF-2018K1A4A3A02060572)

Authors: Myeong Jin Ju, Christine Huang, Daniel J. Wahl, Yifan Jian, Marinko V. Sarunic

Distinct brain metabolic patterns separately associated with cognition, motor function, and aging in Parkinson's disease dementia

Journal Article published Dec 2017 in Neurobiology of Aging volume 60 on pages 81 to 91

Research funded by Neurotrack Technologies | National Institute of Biomedical Imaging and Bioengineering | Novartis Pharmaceuticals Corporation | CereSpir, Inc | Canadian Institutes of Health Research | Janssen Alzheimer Immunotherapy Research & Development, LLC | Pfizer | AbbVie | Cogstate | Bristol-Myers Squibb | University of Manitoba | Eisai | National Institute on Aging | Euroimmun | Ministry of Education and Science of Korea | U.S. Department of Defense (W81XWH-12-2-0012) | King Saud University | Lundbeckfonden | Lumosity | Elan Pharmaceuticals, Inc | IXICO Ltd | National Institutes of Health | Piramal Imaging | Fondation Brain Canada | Takeda Pharmaceutical Company | Alzheimer Society of Manitoba | Transition Therapeutics | Servier | Alzheimer's Disease Neuroimaging Initiative (U01 AG024904) | Genentech | Johnson and Johnson | Meso Scale Diagnostics | GE Healthcare | Eli Lilly and Company | Asan Institute for Life Sciences | Biogen | Natural Sciences and Engineering Research Council of Canada | Roche | Merck | Fujirebio Europe | Dr Paul H. T. Tholakson Foundation | Araclon Biotech | Alzheimer's Drug Discovery Foundation | Alzheimer's Association | NeuroRx Research | Manitoba Medical Services Foundation | BioClinica

Authors: Ji Hyun Ko, Audrey Katako, Maram Aljuaid, Andrew L. Goertzen, Andrew Borys, Douglas E. Hobson, Seok Min Kim, Chong Sik Lee

Secreted amyloid precursor protein alpha activates neuronal insulin receptors and prevents diabetes-induced encephalopathy

Journal Article published May 2018 in Experimental Neurology volume 303 on pages 29 to 37

Research funded by Canadian Diabetes Association | Alzheimer's Society of Canada, Manitoba Health Research | St Boniface Hospital Research Foundation (SBHF-7069) | Canadian Institutes of Health Research (RPA-113765) | Alzheimer Society of Manitoba | McCrorie-West Family

Authors: Brent D. Aulston, Jason Schapansky, YaWen Huang, Gary L. Odero, Gordon W. Glazner

Strain differences in hippocampal synaptic dysfunction in the TgCRND8 mouse model of Alzheimer's disease: Implications for improving translational capacity

Journal Article published Jan 2019 in Molecular and Cellular Neuroscience volume 94 on pages 11 to 22

Research funded by St. Boniface Hospital Research Foundation (1406-3216, 1410-3216) | Alzheimer Society of Manitoba | The Honourable Douglas and Patricia Everett and Royal Canadian Properties Limited Endowment Fund (1403-3131)

Authors: Wanda M. Snow, Kensuke Oikawa, Jelena Djordjevic, Benedict C. Albensi

A review of clinical treatment considerations of donepezil in severe Alzheimer's disease

Journal Article published 29 Jul 2018 in CNS Neuroscience & Therapeutics volume 24 issue 10 on pages 876 to 888

Research funded by Research Manitoba | St. Boniface Hospital Research Foundation (1406-3216, 1410-3216) | Alzheimer Society of Manitoba | The Honourable Douglas and Patricia Everett and Royal Canadian Properties Limited Endowment Fund (1403-3131)

Authors: Aida Adlimoghaddam, Melanie Neuendorff, Banibrata Roy, Benedict C. Albensi

Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice

Journal Article published May 2016 in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease volume 1862 issue 5 on pages 1027 to 1036

Research funded by Canadian Institutes of Health Research (MOP 106706) | CIHR Vanier Doctoral Fellowship (200911CVG-217548-192773) | University of British Columbia (6456) | CIHR Canadian Graduate Scholarships Master's (6556) | Four Year Doctoral Fellowship (6456, 6456) | Alzheimer Society of B.C. (1406) | Comissao Technica de Atribuicao de Bolsas para Estudos Pos-Graduados Macao (12113)

Authors: Jérôme Robert, Sophie Stukas, Emily Button, Wai Hang Cheng, Michael Lee, Jianjia Fan, Anna Wilkinson, Iva Kulic, Samuel D. Wright, Cheryl L. Wellington

Gray matter changes in asymptomatic C9orf72 and GRN mutation carriers

Journal Article published 2018 in NeuroImage: Clinical volume 18 on pages 591 to 598

Research funded by Pacific Alzheimer's Research Foundation (C06-01) | Genome British Columbia | Canadian Institutes of Health Research (179009, 74580) | CIHR Clinical Genetics Investigatorship award | PARF | Alzheimer Society of B.C. | National Institutes of Health (R01 NS065782, R01 AG055121-01A1) | Fondation Brain Canada | Natural Sciences and Engineering Research Council of Canada | Alzheimer's society Research program

Authors: Karteek Popuri, Emma Dowds, Mirza Faisal Beg, Rakesh Balachandar, Mahadev Bhalla, Claudia Jacova, Adrienne Buller, Penny Slack, Pheth Sengdy, Rosa Rademakers, Dana Wittenberg, Howard H. Feldman, Ian R. Mackenzie, Ging-Yuek R. Hsiung

Wavefront sensorless adaptive optics fluorescence biomicroscope for in vivo retinal imaging in mice

Journal Article published 3 Dec 2015 in Biomedical Optics Express volume 7 issue 1 on page 1

Research funded by Alzheimer Society of B.C. | Canadian Institutes of Health Research | Michael Smith Foundation for Health Research | National Eye Institute (P30EY012576) | National Science Foundation (I/UCRC CBSS Grant) | Natural Sciences and Engineering Research Council of Canada | University of California, Davis (RISE Grant)

Authors: Daniel J. Wahl, Yifan Jian, Stefano Bonora, Robert J. Zawadzki, Marinko V. Sarunic