Metadata Search
Age UK
Page 1 of 71 results
Sort by: relevance publication year Download as CSV

3D shape analysis of the brain's third ventricle using a midplane encoded symmetric template model

Journal Article published Jun 2016 in Computer Methods and Programs in Biomedicine volume 129 on pages 51 to 62

Research funded by Royal Society of Edinburgh | National Research Foundation of Korea (NRF-2012K2A1A2033133, NRF-2013R1A1A2063656) | Age UK | Row Fogo Charitable Trust (R35865) | SINAPSE | Biotechnology and Biological Sciences Research Council | Medical Research Council (G0701120) | Economic and Social Research Council | Engineering and Physical Sciences Research Council | Centre of Cognitive Ageing and Cognitive Epidemiology (G0700704/84698)

Authors: Jaeil Kim, Maria del C. Valdés Hernández, Natalie A. Royle, Susana Muñoz Maniega, Benjamin S. Aribisala, Alan J. Gow, Mark E. Bastin, Ian J. Deary, Joanna M. Wardlaw, Jinah Park

Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936

Journal Article published 16 Feb 2018 in PLOS ONE volume 13 issue 2 on page e0192604

Research funded by Age UK (Disconnected Mind project grant) | Medical Research Council (G0701120, G1001245, MR/M013111/1, G0700704, MR/K026992/1) | Biotechnology and Biological Sciences Research Council | Economic and Social Research Council (C106891X)

Authors: Zander Crook, Tom Booth, Simon R. Cox, Janie Corley, Dominika Dykiert, Paul Redmond, Alison Pattie, Adele M. Taylor, Sarah E. Harris, John M. Starr, Ian J. Deary

Editors: Ornit Chiba-Falek

Symptoms During Carotid Sinus Massage, Not Hemodynamic Change, Are Associated with White Matter Hyperintensity Volume on Magnetic Resonance Imaging

Journal Article published Oct 2014 in Journal of the American Geriatrics Society volume 62 issue 10 on pages 1988 to 1989

Research funded by Research into Ageing Fund | Age UK | British Geriatrics Society | the National Institute for Health Research Newcastle Biomedical Research Centre in Ageing & Chronic Disease

Authors: Claire McDonald, Michael Firbank, Mark Pearce, Andrew M. Blamire, Julia L. Newton, Simon Kerr

Relationships between socioeconomic position and objectively measured sedentary behaviour in older adults in three prospective cohorts

Journal Article published Jun 2017 in BMJ Open volume 7 issue 6 on page e016436

Research funded by Medical Research Council | Age UK

Authors: Richard John Shaw, Iva Čukić, Ian J Deary, Catharine R Gale, Sebastien FM Chastin, Philippa M Dall, Dawn A Skelton, Geoff Der

Topical Beta-Blockers and Cardiovascular Mortality: Systematic Review and Meta-Analysis with Data from the EPIC-Norfolk Cohort Study

Journal Article published 23 Aug 2016 in Ophthalmic Epidemiology volume 23 issue 5 on pages 277 to 284

Research funded by Age UK (262) | Cancer Research UK (C864/A14136) | Fight for Sight UK (Richard Desmond Charitable trust award to PJF) | Medical Research Council (G1000143) | National Institute for Health Research (Biomedical Research centre for Ophthalmology,Clinical Lectureship for JLY) | Wellcome Trust (Clinical Research training fellowship for APK)

Authors: Claude Pinnock, Jennifer L. Y. Yip, Anthony P. Khawaja, Robert Luben, Shabina Hayat, David C. Broadway, Paul J. Foster, Kay-Tee Khaw, Nick Wareham

The impact of volunteer befriending services for older people at the end of life: Mechanisms supporting wellbeing

Journal Article published 23 Feb 2016 in Progress in Palliative Care volume 24 issue 3 on pages 159 to 164

Research funded by Age UK (N/a)

Authors: Clare Gardiner, Sarah Barnes

DNA methylation and the epigenetic clock in relation to physical frailty in older people: the Lothian Birth Cohort 1936

Journal Article published 3 Aug 2018 in Clinical Epigenetics volume 10 issue 1

Research funded by Medical Research Council (MR/K026992/1, Mr/M01311/1) | Age UK (G1001245/96077)

Authors: Catharine R. Gale, Riccardo E. Marioni, Sarah E. Harris, John M. Starr, Ian J. Deary

Genetic prediction of male pattern baldness

Journal Article published 14 Feb 2017 in PLOS Genetics volume 13 issue 2 on page e1006594

Research funded by Medical Research Council (MR/K026992/1) | Age UK (Disconnected Mind Project)

Authors: Saskia P. Hagenaars, W. David Hill, Sarah E. Harris, Stuart J. Ritchie, Gail Davies, David C. Liewald, Catharine R. Gale, David J. Porteous, Ian J. Deary, Riccardo E. Marioni

Editors: Markus M. Noethen

Oxidative stress, redox signalling and endothelial dysfunction in ageing-related neurodegenerative diseases: a role of NADPH oxidase 2

Journal Article published 21 Aug 2014 in British Journal of Clinical Pharmacology volume 78 issue 3 on pages 441 to 453

Research funded by Age UK (RiA 359)

Authors: Sarah Cahill-Smith, Jian-Mei Li

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Journal Article published 12 Jan 2018 in Wellcome Open Research volume 3 on page 4

Research funded by Netherlands Genomics Initiative/Netherlands Consortium for Healthy Aging (050-060-810) | Knut och Alice Wallenberg Foundation (2013.0126) | Royal Society of Edinburgh | The Åke Wiberg foundation | National Institute of Nursing Research (R01-NR012459) | Netherlands Organization for Scientific Research (175.010.2005.011, 911-03-305 012) | National Institute on Aging (R01AG023629, 1R01AG032098- 01A1, N01AG62101, N01AG62103, N01AG62106) | Hjärt-Lungfonden (20140422) | Age UK | Research Institute for Diseases in the Elderly (014-93-015) | Federal State of Mecklenburg-West Pomerania | National Center for Advancing Translation Studies (UL1-TR-000040, UL1-TR-001079, UL1-TR-001881, DK063491) | Bundesministerium für Bildung und Forschung (03Z1CN22) | European Commission FP6 (LSHG-CT-2006-01947) | Scottish Funding Council (HR03006) | Leids Universitair Medisch Centrum | National Heart, Lung, and Blood Institute (N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168, N01-HC-95169, N02-HL-64278, R01-HL077612, R01-HL120393, HHSN268201200036C, HHSN268200800007C, N01HC55222, N01HC85079, N01HC85080, N01HC85081, N01HC85082, N01HC85083, N01HC85086;grants:U01HL080295, R01HL068986, R01HL087652, R01HL105756, R01HL103612, R01HL120393, R01HL130114, HHSN268201100005C, HHSN268201100006C, HHSN268201100007C, HHSN268201100008C, HHSN268201100009C, HHSN268201100010C, HHSN268201100011C, HHSN268201100012C, HHSN268201500001I) | Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (33CS30-148470/1, 33CSCO-134276/1, 33CSCO-108796, 324730_135673, 3247BO-104283, 3247BO-104288, 3247BO-104284, 3247-065896, 3100-059302, 3200-052720, 3200-042532, 4026-028099, PMPDP3_129021/1, PMPDP3_141671/1) | U.S. Department of Health and Human Services (HHSN268201500003I) | National Institutes of Health (N01-AG012100, R01-AG028050) | U.S. Environmental Protection Agency (RD831697) | The Marcus Borgström Foundation | Wellcome Trust (202849, 068545, 064890, 098051, 084703) | National Center for Advancing Translational Sciences (UL1TR000124) | The Vleugels Foundation | Medical Research Council (G0501942, G0902313, MR/N011317/1, G1000861, G0000934, MR/K026992/1, K2007-66X-20270-01-3, 2011-2354, HHSN268200782096C) | Centre National de Génotypage | Vetenskapsrådet (2012-1397) | National Institute of Diabetes and Digestive and Kidney Disease Diabetes Research Center (DK063491) | National Institute of Environmental Health Sciences (ZIA ES 043012) | Academy of Finland (213506, 129680, 265240, 263278) | Scottish Government Health Directorates (CZD/16/6) | Economic and Social Research Council (ES/H029745/1) | Swedish Society for Medical Research | Dutch Science Organisation (916.14.023) | Ministry of Science, Education and Sports of the Republic of Croatia (108-1080315-0302) | The Kjell och Märta Beijers Foundation

Authors: Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain, Albert V. Smith, Megan L. Grove, Traci M. Bartz, Ma'en Obeidat, Michael A. Province, Wei Gao, Beenish Qaiser, David J. Porteous, Patricia A. Cassano, Tarunveer S. Ahluwalia, Niels Grarup, Jin Li, Elisabeth Altmaier, Jonathan Marten, Sarah E. Harris, Ani Manichaikul, Tess D. Pottinger, Ruifang Li-Gao, Allan Lind-Thomsen, Anubha Mahajan, Lies Lahousse, Medea Imboden, Alexander Teumer, Bram Prins, Leo-Pekka Lyytikäinen, Gudny Eiriksdottir, Nora Franceschini, Colleen M. Sitlani, Jennifer A. Brody, Yohan Bossé, Wim Timens, Aldi Kraja, Anu Loukola, Wenbo Tang, Yongmei Liu, Jette Bork-Jensen, Johanne M. Justesen, Allan Linneberg, Leslie A. Lange, Rajesh Rawal, Stefan Karrasch, Jennifer E. Huffman, Blair H. Smith, Gail Davies, Kristin M. Burkart, Josyf C. Mychaleckyj, Tobias N. Bonten, Stefan Enroth, Lars Lind, Guy G. Brusselle, Ashish Kumar, Beate Stubbe, Mika Kähönen, Annah B. Wyss, Bruce M. Psaty, Susan R. Heckbert, Ke Hao, Taina Rantanen, Stephen B. Kritchevsky, Kurt Lohman, Tea Skaaby, Charlotta Pisinger, Torben Hansen, Holger Schulz, Ozren Polasek, Archie Campbell, John M. Starr, Stephen S. Rich, Dennis O. Mook-Kanamori, Åsa Johansson, Erik Ingelsson, André G. Uitterlinden, Stefan Weiss, Olli T. Raitakari, Vilmundur Gudnason, Kari E. North, Sina A. Gharib, Don D. Sin, Kent D. Taylor, George T. O'Connor, Jaakko Kaprio, Tamara B. Harris, Oluf Pederson, Henrik Vestergaard, James G. Wilson, Konstantin Strauch, Caroline Hayward, Shona Kerr, Ian J. Deary, R. Graham Barr, Renée de Mutsert, Ulf Gyllensten, Andrew P. Morris, M. Arfan Ikram, Nicole Probst-Hensch, Sven Gläser, Eleftheria Zeggini, Terho Lehtimäki, David P. Strachan, Josée Dupuis, Alanna C. Morrison, Ian P. Hall, Martin D. Tobin, Stephanie J. London, Understanding Society Scientific Group

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Journal Article published 21 Jun 2018 in Wellcome Open Research volume 3 on page 4

Research funded by Netherlands Genomics Initiative/Netherlands Consortium for Healthy Aging (050-060-810) | Knut och Alice Wallenberg Foundation (2013.0126) | Royal Society of Edinburgh | The Åke Wiberg foundation | National Institute of Nursing Research (R01- NR012459) | Netherlands Organization for Scientific Research (175.010.2005.011, 911-03-305 012) | National Institute on Aging (R01AG023629, 1R01AG032098- 01A1, N01AG62101, N01AG62103, N01AG62106) | Hjärt-Lungfonden (20140422) | Age UK | Research Institute for Diseases in the Elderly (014-93-015) | Federal State of Mecklenburg-West Pomerania | National Center for Advancing Translation Studies (UL1-TR-000040, UL1-TR-001079, UL1-TR-001881, DK063491) | Bundesministerium für Bildung und Forschung (03Z1CN22) | European Commission FP6 (LSHG-CT-2006-01947) | Scottish Funding Council (HR03006) | Leids Universitair Medisch Centrum | National Heart, Lung, and Blood Institute (HHSN268201300046C, HHSN268201300047C, HHSN268201300048C, HHSN268201300049C, HHSN268201300050C, N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168, N01-HC-95169, N02-HL-64278, R01-HL077612, R01-HL120393, HHSN268201200036C, HHSN268200800007C, N01HC55222, N01HC85079, N01HC85080, N01HC85081, N01HC85082, N01HC85083, N01HC85086; grants: U01HL080295, R01HL068986, R01HL087652, R01HL105756, R01HL103612, R01HL120393, R01HL130114, HHSN268201100005C, HHSN268201100006C, HHSN268201100007C, HHSN268201100008C, HHSN268201100009C, HHSN268201100010C, HHSN268201100011C, HHSN268201100012C, HHSN268201500001I) | Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (33CS30-148470/1, 33CSCO-134276/1, 33CSCO-108796, 324730_135673, 3247BO-104283, 3247BO-104288, 3247BO-104284, 3247-065896, 3100-059302, 3200-052720, 3200-042532, 4026-028099, PMPDP3_129021/1, PMPDP3_141671/1) | U.S. Department of Health and Human Services (HHSN268201500003I) | National Institutes of Health (N01-AG012100, R01-AG028050) | U.S. Environmental Protection Agency (RD831697) | The Marcus Borgström Foundation | Wellcome Trust (202849, 068545, 064890, 098051, 084703) | National Center for Advancing Translational Sciences (UL1TR001881) | National Institute of General Medical Sciences (U54GM115428) | The Vleugels Foundation | Centre National de Génotypage | Vetenskapsrådet (2012-1397) | National Institute of Diabetes and Digestive and Kidney Disease Diabetes Research Center (DK063491) | National Institute of Environmental Health Sciences (ZIA ES 043012) | Academy of Finland (213506, 129680, 265240, 263278) | Scottish Government Health Directorates (CZD/16/6) | Economic and Social Research Council (ES/H029745/1) | Medical Research Council Canada (G0501942, G0902313, MR/N011317/1, G1000861, G0000934, MR/K026992/1, K2007-66X-20270-01-3, 2011-2354, HHSN268200782096C) | Swedish Society for Medical Research | Dutch Science Organisation (916.14.023) | Ministry of Science, Education and Sports of the Republic of Croatia (108-1080315-0302) | The Kjell och Märta Beijers Foundation

Authors: Victoria E. Jackson, Jeanne C. Latourelle, Louise V. Wain, Albert V. Smith, Megan L. Grove, Traci M. Bartz, Ma'en Obeidat, Michael A. Province, Wei Gao, Beenish Qaiser, David J. Porteous, Patricia A. Cassano, Tarunveer S. Ahluwalia, Niels Grarup, Jin Li, Elisabeth Altmaier, Jonathan Marten, Sarah E. Harris, Ani Manichaikul, Tess D. Pottinger, Ruifang Li-Gao, Allan Lind-Thomsen, Anubha Mahajan, Lies Lahousse, Medea Imboden, Alexander Teumer, Bram Prins, Leo-Pekka Lyytikäinen, Gudny Eiriksdottir, Nora Franceschini, Colleen M. Sitlani, Jennifer A. Brody, Yohan Bossé, Wim Timens, Aldi Kraja, Anu Loukola, Wenbo Tang, Yongmei Liu, Jette Bork-Jensen, Johanne M. Justesen, Allan Linneberg, Leslie A. Lange, Rajesh Rawal, Stefan Karrasch, Jennifer E. Huffman, Blair H. Smith, Gail Davies, Kristin M. Burkart, Josyf C. Mychaleckyj, Tobias N. Bonten, Stefan Enroth, Lars Lind, Guy G. Brusselle, Ashish Kumar, Beate Stubbe, Mika Kähönen, Annah B. Wyss, Bruce M. Psaty, Susan R. Heckbert, Ke Hao, Taina Rantanen, Stephen B. Kritchevsky, Kurt Lohman, Tea Skaaby, Charlotta Pisinger, Torben Hansen, Holger Schulz, Ozren Polasek, Archie Campbell, John M. Starr, Stephen S. Rich, Dennis O. Mook-Kanamori, Åsa Johansson, Erik Ingelsson, André G. Uitterlinden, Stefan Weiss, Olli T. Raitakari, Vilmundur Gudnason, Kari E. North, Sina A. Gharib, Don D. Sin, Kent D. Taylor, George T. O'Connor, Jaakko Kaprio, Tamara B. Harris, Oluf Pederson, Henrik Vestergaard, James G. Wilson, Konstantin Strauch, Caroline Hayward, Shona Kerr, Ian J. Deary, R. Graham Barr, Renée de Mutsert, Ulf Gyllensten, Andrew P. Morris, M. Arfan Ikram, Nicole Probst-Hensch, Sven Gläser, Eleftheria Zeggini, Terho Lehtimäki, David P. Strachan, Josée Dupuis, Alanna C. Morrison, Ian P. Hall, Martin D. Tobin, Stephanie J. London, Understanding Society Scientific Group

Peptides from Tetraspanin CD9 Are Potent Inhibitors of Staphylococcus Aureus Adherence to Keratinocytes

Journal Article published 28 Jul 2016 in PLOS ONE volume 11 issue 7 on page e0160387

Research funded by Age UK (370)

Authors: Jennifer K. Ventress, Lynda J. Partridge, Robert C. Read, Daniel Cozens, Sheila MacNeil, Peter N. Monk

Editors: Johanna M Brandner

Cognitive function in early and later life is associated with blood glucose in older individuals: analysis of the Lothian Birth Cohort of 1936

Journal Article published 2 Jun 2018 in Diabetologia volume 61 issue 9 on pages 1946 to 1955

Research funded by Medical Research Council (MR/K026992/1) | Age UK (Research Into Ageing programme grant)

Authors: Drew M. Altschul, John M. Starr, Ian J. Deary

Systematic comparative validation of self-report measures of sedentary time against an objective measure of postural sitting (activPAL)

Journal Article published 26 Feb 2018 in International Journal of Behavioral Nutrition and Physical Activity volume 15 issue 1

Research funded by Medical Research Council (GB) (MR/K025023/1, Mr/M01311/1) | Age UK (G1001245/96077) | Medical Research Council (MR/K026992/1)

Authors: S. F. M. Chastin, on behalf of the Seniors USP team, M. L. Dontje, D. A. Skelton, I. Čukić, R. J. Shaw, J. M. R. Gill, C. A. Greig, C. R. Gale, I. J. Deary, G. Der, P. M. Dall

Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia: evidence from a cohort study

Journal Article published Jun 2017 in Alzheimer's & Dementia volume 13 issue 6 on pages 634 to 643

Research funded by Wellcome Trust | Row Fogo Charitable Trust | Age UK | Scottish Funding Council

Authors: Joanna M. Wardlaw, Stephen J. Makin, Maria C. Valdés Hernández, Paul A. Armitage, Anna K. Heye, Francesca M. Chappell, Susana Muñoz-Maniega, Eleni Sakka, Kirsten Shuler, Martin S. Dennis, Michael J. Thrippleton

The Role of Age-Related Declines in Subcortical Auditory Processing in Speech Perception in Noise

Journal Article published 23 May 2016 in Journal of the Association for Research in Otolaryngology volume 17 issue 5 on pages 441 to 460

Research funded by Action on Hearing Loss (S19) | Age UK (S19)

Authors: Tim Schoof, Stuart Rosen

F-dynamics: Automated quantification of dendrite filopodia dynamics in living neurons

Journal Article published Oct 2014 in Journal of Neuroscience Methods volume 236 on pages 148 to 156

Research funded by Age UK (320)

Authors: Rita Hendricusdottir, Jeroen H.M. Bergmann

Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence

Journal Article published Oct 2017 in Cell Reports volume 21 issue 3 on pages 679 to 691

Research funded by Seventh Framework Programme (HEALTH-F2-2009-242167, HEALTH-F2-2009-241498) | Age UK (MR/K026992/1) | U.S. Department of Defense (W81XWH-15-1-0361, W81XWH-15-1-0361) | Vlaams Instituut voor Biotechnologie | Wellcome Trust | Medical Research Council (MRC) Centre (MR/L010305/1, G0801418) | Federation of European Biochemistry Societies | Biotechnology and Biological Sciences Research Council | Medical Research Council | Marie Curie (FP7-PEOPLE-2010-IEF) | Associazione Italiana Sindrome X Fragile

Authors: Esperanza Fernández, Mark O. Collins, René A.W. Frank, Fei Zhu, Maksym V. Kopanitsa, Jess Nithianantharajah, Sarah A. Lemprière, David Fricker, Kathryn A. Elsegood, Catherine L. McLaughlin, Mike D.R. Croning, Colin Mclean, J. Douglas Armstrong, W. David Hill, Ian J. Deary, Giulia Cencelli, Claudia Bagni, Menachem Fromer, Shaun M. Purcell, Andrew J. Pocklington, Jyoti S. Choudhary, Noboru H. Komiyama, Seth G.N. Grant

Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 study

Journal Article published 17 Oct 2016 in British Journal of Ophthalmology volume 101 issue 7 on pages 993 to 998

Research funded by Wellcome Trust (075611) | Engineering and Physical Sciences Research Council (EP/M005976/1) | Biotechnology and Biological Sciences Research Council | Age UK (MR/K026992/1)

Authors: Sarah McGrory, Adele M Taylor, Mirna Kirin, Janie Corley, Alison Pattie, Simon R Cox, Baljean Dhillon, Joanna M Wardlaw, Fergus N Doubal, John M Starr, Emanuele Trucco, Thomas J MacGillivray, Ian J Deary

Metric to quantify white matter damage on brain magnetic resonance images

Journal Article published 16 Aug 2017 in Neuroradiology volume 59 issue 10 on pages 951 to 962

Research funded by Row Fogo Charitable Trust (BRO-D.FID3668413) | Age UK (Disconnected Mind Project) | Medical Research Council (MR/K026992/1, G0701120) | Wellcome Trust (088134/Z/09) | Horizon 2020 (PhC-03-15, Project no. 666881) | Fondation Leducq (16 CVD 05) | Innovate UK (46917-348146)

Authors: Maria Del C. Valdés Hernández, Francesca M. Chappell, Susana Muñoz Maniega, David Alexander Dickie, Natalie A. Royle, Zoe Morris, Devasuda Anblagan, Eleni Sakka, Paul A. Armitage, Mark E. Bastin, Ian J. Deary, Joanna M. Wardlaw