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National Centre for the Replacement, Refinement and Reduction of Animals in Research
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The epigenetics of multiple sclerosis and other related disorders

Journal Article published Mar 2014 in Multiple Sclerosis and Related Disorders volume 3 issue 2 on pages 163 to 175

Research funded by National Multiple Sclerosis Society | National Centre for the Replacement, Refinement and Reduction of Animals in Research | MS Research Foundation of the Netherlands | Multiple Sclerosis Society of Great Britain and Northern Ireland

Authors: Peter J. van den Elsen, Marja C.J.A. van Eggermond, Fabiola Puentes, Paul van der Valk, David Baker, Sandra Amor

A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons

Journal Article published Apr 2018 in Current Biology volume 28 issue 8 on pages 1265 to 1272.e4

Research funded by MRC (MC_U105178790) | NC3Rs (NC/N001753/1) | Van Geest

Authors: Alessio Vagnoni, Simon L. Bullock

Self-renewing macrophages – A new line of enquiries in mononuclear phagocytes

Journal Article published Feb 2015 in Immunobiology volume 220 issue 2 on pages 169 to 174

Research funded by National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC/L00058X/1)

Authors: Gyorgy Fejer, Shagun Sharma, Ildiko Gyory

Induction of innate cytokine responses by respiratory mucosal challenge with R848 in zebrafish, mice, and humans

Journal Article published Jul 2019 in Journal of Allergy and Clinical Immunology volume 144 issue 1 on pages 342 to 345.e7

Research funded by National Centre for the Replacement, Refinement and Reduction of Animals in Research | Wellcome Trust | Imperial College London | Public Health England | Rosetrees Trust (M370) | National Institute for Health Research Health Protection Research Unit | Imperial College Healthcare Trust | NIHR Biomedical Research Centre (P45058)

Authors: Fränze Progatzky, Akhilesh Jha, Madina Wane, Ryan S. Thwaites, Spyridon Makris, Robin J. Shattock, Cecilia Johansson, Peter J. Openshaw, Laurence Bugeon, Trevor T. Hansel, Margaret J. Dallman

Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response

Journal Article published 1 Jun 2021 in PLOS Biology volume 19 issue 6 on page e3001247

Research funded by Medical Research Council (MR/N008707/1) | National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC/P002390/1) | Fundação para a Ciência e a Tecnologia (SFRH/BPD/96176/201IF/00735/2014) | Deutsche Forschungsgemeinschaft (CRC/TRR 124) | Fondation de l'Avenir pour la Recherche Médicale Appliquée

Authors: Monica Sueiro-Olivares, Jennifer Scott, Sara Gago, Dunja Petrovic, Emilia Kouroussis, Jasmina Zivanovic, Yidong Yu, Marlene Strobel, Cristina Cunha, Darren Thomson, Rachael Fortune-Grant, Sina Thusek, Paul Bowyer, Andreas Beilhack, Agostinho Carvalho, Elaine Bignell, Milos R. Filipovic, Jorge Amich

Editors: Joseph Heitman

CRISPR/Cas9-mediated generation and analysis of N terminus polymorphic models of β2AR in isogenic hPSC-derived cardiomyocytes

Journal Article published Mar 2021 in Molecular Therapy - Methods & Clinical Development volume 20 on pages 39 to 53

Research funded by National Centre for the Replacement, Refinement and Reduction of Animals in Research | British Heart Foundation

Authors: Alexander Kondrashov, Nurul A.N. Mohd Yusof, Alveera Hasan, Joëlle Goulding, Thusharika Kodagoda, Duc M. Hoang, Nguyen T.N. Vo, Tony Melarangi, Nazanin Dolatshad, Julia Gorelik, Stephen J. Hill, Sian E. Harding, Chris Denning

Ultrasound Induced Fluorescence of Nanoscale Liposome Contrast Agents

Journal Article published 28 Jul 2016 in PLOS ONE volume 11 issue 7 on page e0159742

Research funded by China Scholarship Council | Engineering and Physical Sciences Research Council (EP/J017566/1EP/J001953/1) | National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC/L00187X/1)

Authors: Qimei Zhang, Stephen P. Morgan, Paul O’Shea, Melissa L. Mather

Editors: Colin Johnson

Hepatic arterial spin labelling MRI: an initial evaluation in mice

Journal Article published Feb 2015 in NMR in Biomedicine volume 28 issue 2 on pages 272 to 280

Research funded by Medical Research Council (MR/K026739/1MRC G100149MR/J013110/1MR.G1000411-2/1) | National Centre for the Replacement, Refinement and Reduction of Animals in Research | Wellcome | British Heart Foundation (C1519/A10331C1519/A16463)

Authors: R. Ramasawmy, A. E. Campbell-Washburn, J. A. Wells, S. P. Johnson, R. B. Pedley, S. Walker-Samuel, M. F. Lythgoe

Prof Benchie and Dr Athena-A modern tragedy…

Journal Article published Aug 2015 in Evidence-based Preclinical Medicine volume 2 issue 1 on page e00008

Research funded by National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC/L000970/1)

Authors: Malcolm Macleod

Assessment of mGluR5 KO mice under conditions of low stress using a rodent touchscreen apparatus reveals impaired behavioural flexibility driven by perseverative responses

Journal Article published Dec 2019 in Molecular Brain volume 12 issue 1

Research funded by Ministry of Health and Welfare (HI14C2173) | National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC/N001451/1)

Authors: Jisoo Lim, Eosu Kim, Hyun Jong Noh, Shinwon Kang, Benjamin U. Phillips, Dong Goo Kim, Timothy J. Bussey, Lisa Saksida, Christopher J. Heath, Chul Hoon Kim