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Addenbrooke's Charitable Trust, Cambridge University Hospitals
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Priming and de-priming of neutrophil responses in vitro and in vivo

Journal Article published 5 Jul 2018 in European Journal of Clinical Investigation on page e12967

Research funded by National Institute for Health Research | Addenbrooke's Charitable Trust, Cambridge University Hospitals | Cancer Research UK | Gates Cambridge Trust | Wellcome Trust | Wolfson Foundation | Medical Research Council (MR/M012328, MRNO2995X/1) | MedImmune | British Medical Association | British Lung Foundation (PRG16-13) | GlaxoSmithKline

Authors: Katja L. Vogt, Charlotte Summers, Edwin R. Chilvers, Alison M. Condliffe

Free-breathing black-blood CINE fast-spin echo imaging for measuring abdominal aortic wall distensibility: a feasibility study

Journal Article published 13 Apr 2017 in Physics in Medicine and Biology volume 62 issue 10 on pages N204 to N218

Research funded by Ministry of Science and Technology, Taiwan (MOST 105-2811-E-002-049, 105-2221-E-002-142-MY3, MOST 105-2314-B-006-044-MY2) | Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: Jyh-Miin Lin, Andrew J Patterson, Tzu-Cheng Chao, Chengcheng Zhu, Hing-Chiu Chang, Jason Mendes, Hsiao-Wen Chung, Jonathan H Gillard, Martin J Graves

DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development

Journal Article published 15 Nov 2017 in Gut on page gutjnl-2017-314817

Research funded by Crohn’s in Childhood Research Association (CICRA) | Crohn’s and Colitis in Childhood (“3Cs”) | Bundesministerium für Bildung und Forschung | Addenbrooke's Charitable Trust, Cambridge University Hospitals | Evelyn Trust | Wellcome Trust and the Royal Society | Wellcome Trust | Medical Research Council | Deutsche Forschungsgemeinschaft | Newlife Foundation for Disabled Children

Authors: Judith Kraiczy, Komal M Nayak, Kate J Howell, Alexander Ross, Jessica Forbester, Camilla Salvestrini, Roxana Mustata, Sally Perkins, Amanda Andersson-Rolf, Esther Leenen, Anke Liebert, Ludovic Vallier, Philip C Rosenstiel, Oliver Stegle, Gordon Dougan, Robert Heuschkel, Bon-Kyoung Koo, Matthias Zilbauer

Biology of childhood germ cell tumours, focussing on the significance of microRNAs

Journal Article published 9 Oct 2014 in Andrology volume 3 issue 1 on pages 129 to 139

Research funded by Cancer Research UK | Medical Research Council | Sparks | CHILDREN with CANCER UK | Great Ormond Street Hospital Charity | Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: M. J. Murray, J. C. Nicholson, N. Coleman

Observations on the ex situ perfusion of livers for transplantation

Journal Article published 14 Mar 2018 in American Journal of Transplantation volume 18 issue 8 on pages 2005 to 2020

Research funded by Addenbrooke's Charitable Trust, Cambridge University Hospitals | National Institute for Health Research

Authors: Christopher J. E. Watson, Vasilis Kosmoliaptsis, Caitlin Pley, Lucy Randle, Corinna Fear, Keziah Crick, Alexander E. Gimson, Michael Allison, Sara Upponi, Rebecca Brais, Ina Jochmans, Andrew J. Butler

Visual field testing for glaucoma patients using iPad app

Dataset published 1 Feb 2018 in http://isrctn.com/

Research funded by Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: Yu Xiang George Kong

Significant association between TNFAIP3 inactivation and biased immunoglobulin heavy chain variable region 4-34 usage in mucosa-associated lymphoid tissue lymphoma

Journal Article published 7 Aug 2017 in The Journal of Pathology volume 243 issue 1 on pages 3 to 8

Research funded by Bloodwise | UK and Kay Kendal Leukaemia Fund | Medical Research Council | Addenbrooke's Charitable Trust, Cambridge University Hospitals | Pathological Society of Great Britain and Ireland | China Scholarship Council | Ministry of Education of the People's Republic of China

Authors: Sarah Moody, Leire Escudero-Ibarz, Ming Wang, Alexandra Clipson, Eguzkine Ochoa Ruiz, Deborah Dunn-Walters, Xuemin Xue, Naiyan Zeng, Alistair Robson, Shih-Sung Chuang, Sergio Cogliatti, Hongxiang Liu, John Goodlad, Margaret Ashton-Key, Markus Raderer, Yingwen Bi, Ming-Qing Du

The role of individual characteristics and physical frailty on health related quality of life (HRQOL): A cross sectional study of Italian community-dwelling older adults

Journal Article published Nov 2014 in Archives of Gerontology and Geriatrics volume 59 issue 3 on pages 542 to 548

Research funded by Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: Anna Mulasso, Mattia Roppolo, Emanuela Rabaglietti

Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: a feasibility study

Journal Article published 11 Jul 2017 in BMC Genomics volume 18 issue 1

Research funded by Cancer Research UK | Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: Mahesh Iddawela, Oscar Rueda, Jenny Eremin, Oleg Eremin, Jed Cowley, Helena M. Earl, Carlos Caldas

Age-related changes in murine myometrial transcript profile are mediated by exposure to the female sex hormones

Journal Article published 21 Oct 2015 in Aging Cell volume 15 issue 1 on pages 177 to 180

Research funded by National Institute for Health Research | Addenbrooke's Charitable Trust, Cambridge University Hospitals | Evelyn Trust

Authors: Hsu P. Chong, Yolande Cordeaux, Yorain Sri Ranjan, Sylvia Richardson, Benoit Liquet, Gordon C. S. Smith, David Stephen Charnock-Jones

A nested cohort study of 6,248 early breast cancer patients treated in neoadjuvant and adjuvant chemotherapy trials investigating the prognostic value of chemotherapy-related toxicities

Journal Article published Dec 2015 in BMC Medicine volume 13 issue 1

Research funded by Cancer Research UK (C57/A4180, C10097/A7484) | Medical Research Council | Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: Jean E. Abraham, Louise Hiller, Leila Dorling, Anne-Laure Vallier, Janet Dunn, Sarah Bowden, Susan Ingle, Linda Jones, Richard Hardy, Christopher Twelves, Christopher J. Poole, Paul D P Pharoah, Carlos Caldas, Helena M. Earl

The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study

Journal Article published 8 Jul 2016 in PLOS ONE volume 11 issue 7 on page e0158984

Research funded by Medical Research Council | Cancer Research UK | Addenbrooke's Charitable Trust, Cambridge University Hospitals | National Institute for Health Research

Authors: Leila Dorling, Siddhartha Kar, Kyriaki Michailidou, Louise Hiller, Anne-Laure Vallier, Susan Ingle, Richard Hardy, Sarah J. Bowden, Janet A. Dunn, Chris Twelves, Christopher J. Poole, Carlos Caldas, Helena M. Earl, Paul D. P. Pharoah, Jean E. Abraham

Editors: Douglas Thamm

MALT lymphoma: Genetic abnormalities, immunological stimulation and molecular mechanism

Journal Article published Mar 2017 in Best Practice & Research Clinical Haematology volume 30 issue 1-2 on pages 13 to 23

Research funded by Bloodwise | Kay Kendall Leukaemia Fund | Elimination of Leukemia Fund, U.K. | Lady Tata Memorial Trust | Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: Ming-Qing Du

Relationship between carotid plaque surface morphology and perfusion: a 3D DCE-MRI study

Journal Article published 28 Apr 2017 in Magnetic Resonance Materials in Physics, Biology and Medicine volume 31 issue 1 on pages 191 to 199

Research funded by Addenbrooke's Charitable Trust, Cambridge University Hospitals | National Institute for Health Research

Authors: Jianmin Yuan, Gregory Makris, Andrew Patterson, Ammara Usman, Tilak Das, Andrew Priest, Zhongzhao Teng, Sarah Hilborne, Dario Prudencio, Jonathan Gillard, Martin Graves

Combined MR direct thrombus imaging and non-contrast magnetic resonance venography reveal the evolution of deep vein thrombosis: a feasibility study

Journal Article published 30 Aug 2016 in European Radiology volume 27 issue 6 on pages 2326 to 2332

Research funded by Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: I. A. Mendichovszky, A. N. Priest, D. J. Bowden, S. Hunter, I. Joubert, S. Hilborne, M. J. Graves, T. Baglin, D. J. Lomas

Loss of hSef promotes metastasis through upregulation of EMT in prostate cancer

Journal Article published 30 Jan 2017 in International Journal of Cancer volume 140 issue 8 on pages 1881 to 1887

Research funded by Medical Research Council (G1001961) | University of Cambridge (Raymond and Beverly Sackler Studentship) | Prostate Cancer UK | Royal College of Surgeons of England | Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: Satoshi Hori, Karan Wadhwa, Venkat Pisupati, Vincent Zecchini, Antonio Ramos-Montoya, Anne Y Warren, David E Neal, Vincent J Gnanapragasam

The development and optimisation of 3D black-blood R2* mapping of the carotid artery wall

Journal Article published Dec 2017 in Magnetic Resonance Imaging volume 44 on pages 104 to 110

Research funded by Addenbrooke's Charitable Trust, Cambridge University Hospitals | Korea National Institute of Health

Authors: Jianmin Yuan, Martin J. Graves, Andrew J. Patterson, Andrew N. Priest, Pascal P.R. Ruetten, Ammara Usman, Jonathan H. Gillard

Advances in the generation of bioengineered bile ducts

Journal Article published Apr 2018 in Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease volume 1864 issue 4 on pages 1532 to 1538

Research funded by Engineering and Physical Sciences Research Council (EP/R511675/1) | H2020 European Research Council (281335) | Addenbrooke's Charitable Trust, Cambridge University Hospitals (9208, 9980) | Sparks | Medical Research Council (MR/L016761/1) | National Institute for Health Research

Authors: Alexander W. Justin, Kourosh Saeb-Parsy, Athina E. Markaki, Ludovic Vallier, Fotios Sampaziotis

Human Cytomegalovirus Delays Neutrophil Apoptosis and Stimulates the Release of a Prosurvival Secretome

Journal Article published 25 Sep 2017 in Frontiers in Immunology volume 8

Research funded by Medical Research Council (MR/L002108/1, G:0900466, G:0701279) | Gates Cambridge Trust | Addenbrooke's Charitable Trust, Cambridge University Hospitals

Authors: Joanna M. Pocock, Daniel M. L. Storisteanu, Matthew B. Reeves, Jatinder K. Juss, Mark R. Wills, Andrew S. Cowburn, Edwin R. Chilvers

Identifying risk factors for L’Hermitte’s sign after IMRT for head and neck cancer

Journal Article published 4 May 2018 in Radiation Oncology volume 13 issue 1

Research funded by Cancer Research UK (CRUK/A13405, C20/A20917) | Addenbrooke's Charitable Trust, Cambridge University Hospitals (24/15 A/Noble, RG82557)

Authors: Hannah M. Laidley, David J. Noble, Gill C. Barnett, Julia R. Forman, Amy M. Bates, Richard J. Benson, Sarah J. Jefferies, Rajesh Jena, Neil G. Burnet