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Allard Foundation
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Elucidating the Mechanism of Action of the Clinically Approved Taxanes: A Comprehensive Comparison of Local and Allosteric Effects

Journal Article published 14 Jul 2015 in Chemical Biology & Drug Design volume 86 issue 5 on pages 1253 to 1266

Research funded by Allard Foundation | Alberta Cancer Foundation | Natural Sciences and Engineering Research Council of Canada | Alberta Advanced Education and Technology | Alberta Innovates - Technology Futures | Killam Trusts | IODE War Memorial Scholarship | University of Alberta

Authors: Cassandra D. M. Churchill, Mariusz Klobukowski, Jack A. Tuszynski

Ranking the Binding Energies of p53 Mutant Activators and Their ADMET Properties

Journal Article published 11 Dec 2014 in Chemical Biology & Drug Design volume 86 issue 2 on pages 163 to 172

Research funded by Natural Sciences and Engineering Research Council of Canada | Canadian Breast Cancer Foundation | Allard Foundation | Alberta Cancer Foundation Antoine Noujaim Endowment Fund

Authors: Sara Ibrahim Omar, Jack Tuszynski

Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer

Journal Article published 9 Dec 2016 in Protoplasma volume 254 issue 3 on pages 1163 to 1173

Research funded by Allard Foundation | Alberta Cancer Foundation | Alberta Innovates - Technology Futures | Innovates Centres of Research Excellence | Musea Ventures | Commonwealth Universal Research Enhancement Program

Authors: Weiwei Wang, Hangxiao Zhang, Xumin Wang, Jordan Patterson, Philip Winter, Kathryn Graham, Sunita Ghosh, John C. Lee, Christos D. Katsetos, John R. Mackey, Jack A. Tuszynski, Gane Ka-Shu Wong, Richard F. Ludueña

The Unique Binding Mode of Laulimalide to Two Tubulin Protofilaments

Journal Article published 28 Nov 2014 in Chemical Biology & Drug Design volume 86 issue 2 on pages 190 to 199

Research funded by Allard Foundation | Alberta Cancer Foundation | the National Sciences and Engineering Research Council (NSERC) | and Alberta Advanced Education and Technology

Authors: Cassandra D. M. Churchill, Mariusz Klobukowski, Jack A. Tuszynski

Virtual screening using covalent docking to find activators for G245S mutant p53

Journal Article published 7 Sep 2018 in PLOS ONE volume 13 issue 9 on page e0200769

Research funded by Natural Sciences and Engineering Research Council of Canada | Allard Foundation

Authors: Sara Ibrahim Omar, Marco Gaetano Lepre, Umberto Morbiducci, Marco Agostino Deriu, Jack A. Tuszynski

Editors: Sumitra Deb

Chemical synthesis, pharmacological evaluation and in silico analysis of new 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives as potential anti-mitotic agents

Journal Article published Aug 2016 in Bioorganic & Medicinal Chemistry Letters volume 26 issue 16 on pages 3855 to 3861

Research funded by Dayalbagh Educational Institute | National Institute for Science and Technology on Innovation on Neglected Diseases | Prairie-Northwest Chapter | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior | Conselho Nacional de Desenvolvimento Científico e Tecnológico (573642/2008-7) | UM-DAE CBS | Canadian Breast Cancer Foundation | Natural Sciences and Engineering Research Council of Canada | Allard Foundation | INCT/IDN

Authors: Maninder Minu, Deepti Singh, Tejashree Mahaddalkar, Manu Lopus, Philip Winter, Ahmed T. Ayoub, Kristal Missiaen, Tatiana Martins Tilli, Manijeh Pasdar, Jack Tuszynski