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Association Laurette Fugain
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NAP1L1-MLLT10is a rare recurrent translocation that is associated withHOXAactivation and poor treatment response in T-cell acute lymphoblastic leukaemia

Journal Article published 12 Oct 2015 in British Journal of Haematology volume 174 issue 3 on pages 470 to 473

Research funded by Kay Kendall Leukaemia Fund | Association Laurette Fugain | INCa CARAMELE Translational Research and PhD Programmes

Authors: Jonathan Bond, Aurore Touzart, Agata Cieslak, Amélie Trinquand, Tony Marchand, Martine Escoffre, Audrey Contet, Marc Muller, Claudine Schmitt, Thierry Fest, Vahid Asnafi, Elizabeth Macintyre

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis

Journal Article published 12 Sep 2017 in Frontiers in Endocrinology volume 8

Research funded by Association Laurette Fugain | GIS-Institut des Maladies Rares (AO9102LS)

Authors: Isabelle Plo, Christine Bellanné-Chantelot, Matthieu Mosca, Stefania Mazzi, Caroline Marty, William Vainchenker

Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes

Journal Article published Mar 2013 in Leukemia Research volume 37 issue 3 on pages 312 to 319

Research funded by Fondation de France | Association pour la Recherche sur le Cancer | Association Laurette Fugain | Institut National de la Santé et de la Recherche Médicale | Leukaemia and Lymphoma Research

Authors: Carole Le Pogam, Patricia Krief, Stephanie Beurlet, Annie Soulié, Nicole Balitrand, Bruno Cassinat, Helene Cavé, Olivier Kosmider, Niclas Setterblad, Christophe Leboeuf, Laure Sarda-Mantel, Florence Hervatin, Pascal Merlet, Maria-Elena Noguera, Anne Janin, Marika Pla, Michaela Fontenay, Lionel Adès, Pierre Fenaux, Christine Chomienne, Rose Ann Padua, Nader Omidvar

Acute myeloid leukemia impairs natural killer cells through the formation of a deficient cytotoxic immunological synapse

Journal Article published 4 Sep 2014 in European Journal of Immunology volume 44 issue 10 on pages 3068 to 3080

Research funded by Association Laurette Fugain

Authors: Zena Khaznadar, Guylaine Henry, Niclas Setterblad, Sophie Agaugue, Emmanuel Raffoux, Nicolas Boissel, Hervé Dombret, Antoine Toubert, Nicolas Dulphy

Interleukin-22 in Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation

Journal Article published 19 Apr 2016 in Frontiers in Immunology volume 7

Research funded by Agence de la Biomédecine | Agence Nationale de la Recherche (Labex LipSTIC, ANR-11-LABX-0021, ANR-10-IBHU-005) | Etablissement Français du Sang (AO#2011-11, AO#2014-10) | Association Cent pour Sang la Vie | Association Laurette Fugain | IRGHET | Ligue Contre le Cancer | Association for Training, Education and Research in Hematology, Immunology and Transplantation

Authors: Baptiste Lamarthée, Florent Malard, Philippe Saas, Mohamad Mohty, Béatrice Gaugler

Mosaicism of HTLV-1 5′ LTR CpG methylation in the absence of malignancy

Journal Article published Dec 2013 in Virus Research volume 178 issue 2 on pages 452 to 461

Research funded by Association pour la Recherche sur le Cancer | Centre National pour la Recherche Scientifique (CNRS) | Association Laurette Fugain | Fondation pour la Recherche Médicale | Hospices Civils de Lyon, University Lyon I | Ligue Nationale Contre le Cancer (Comités de l’Ain et du Rhône) | Fondation de France | Centre Léon Bérard | Association Guillaume Espoir, Agence Nationale pour la Recherche (ANR) | Institut National de la Santé et de la Recherche Médicale (Inserm) | Ligue Nationale contre le Cancer, comité de l’Ain

Authors: David Sibon, Linda Zane, Manale El Idrissi, Marie-Hélène Delfau-Larue, Antoine Gessain, Olivier Gout, Franck Mortreux, Eric Wattel

Thrombospondin-1 Mimetic Agonist Peptides Induce Selective Death in Tumor Cells: Design, Synthesis, and Structure–Activity Relationship Studies

Journal Article published 2 Sep 2016 in Journal of Medicinal Chemistry volume 59 issue 18 on pages 8412 to 8421

Research funded by Association Laurette Fugain | Fondation pour la Recherche Médicale | Comité de Paris, Ligue Nationale Contre le Cancer | Institut National Du Cancer (INCa-5839) | Fondation ARC pour la Recherche sur le Cancer | French Research Ministry | Labex Michem | SATT-Lutech and DGRTT | Agence Nationale de la Recherche (ANR-12-EMMA-0045) | Ligue Contre le Cancer

Authors: Thomas Denèfle, Héloise Boullet, Linda Herbi, Clara Newton, Ana-Carolina Martinez-Torres, Alexandre Guez, Elodie Pramil, Claire Quiney, Marilyne Pourcelot, Mikail D. Levasseur, Eva Lardé, Roba Moumné, François-Xavier Ogi, Pascal Grondin, Hélène Merle-Beral, Olivier Lequin, Santos A. Susin, Philippe Karoyan

TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis

Journal Article published 1 Oct 2018 in Cancer Discovery on page CD-18-0657

Research funded by Leukemia and Lymphoma Society (7012-16) | Association Laurette Fugain | The Jackson Laboratory Director's Innovation Fund (JAX-DIF 19000-17-13) | Equipe labelisee Ligue Nationale Contre le Cancer | Institut National Du Cancer (INCa-DGOS-INSERM 12551, 2013-PLBIO-09, 2016-PLBIO-068) | National Institutes of Health (1R01CA19454, R01 CA201380) | Lymphoma Research Foundation | Comite Val-d'Oise de la Ligue contre le cancer | Leukemia Research Foundation | Starr Cancer Consortium (I6-A618) | Fondation de France (00067113) | The Jackson Laboratory Cancer Center New Investigator Award (P30CA034196) | The Follicular Lymphoma research Foundation | The Chemotherapy Foundation | National Science Foundation

Authors: Pilar M Dominguez, Hussein Ghamlouch, Wojciech Rosikiewicz, Parveen Kumar, Wendy Béguelin, Lorena Fontan, Martín A. Rivas, Patrycja Pawlikowska, Marine Armand, Enguerran Mouly, Miguel Torres-Martin, Ashley S. Doane, Maria Teresa Calvo Fernandez, Matt Durant, Veronique Della-Valle, Matt Teater, Luisa Cimmino, Nathalie Droin, Saber Tadros, Samaneh Motanagh, Alan H. Shih, Mark A. Rubin, Wayne Tam, Iannis Aifantis, Ross L. Levine, Olivier Elemento, Giorgio Inghirami, Michael R Green, Maria E Figueroa, Olivier A. Bernard, Said Aoufouchi, Sheng Li, Rita Shaknovich, Ari M Melnick

Microenvironmental cues for T-cell acute lymphoblastic leukemia development

Journal Article published 18 Apr 2016 in Immunological Reviews volume 271 issue 1 on pages 156 to 172

Research funded by Centre National de la Recherche Scientifique | Institut National de la Santé et de la Recherche Médicale | Institut Curie | Institut National Du Cancer | Ligue Nationale Contre le Cancer (Equipe Labelisée la Ligue; Ligue de l'Essonne) | Association Laurette Fugain | Fondation de France | Association for International Cancer Research

Authors: Diana Passaro, Christine Tran Quang, Jacques Ghysdael

A role for miR-142-3p in colony-stimulating factor 1-induced monocyte differentiation into macrophages

Journal Article published Aug 2013 in Biochimica et Biophysica Acta (BBA) - Molecular Cell Research volume 1833 issue 8 on pages 1936 to 1946

Research funded by Ligue Contre le Cancer (Conférence de coordination inter-départementale, Comité de Saône-et-Loire) | Association pour la Recherche sur le Cancer | Association Laurette Fugain | Institut National Du Cancer | ANR | Conseil Régional de Bourgogne | Fondation de France | Ligue Contre le Cancer | Ministère de l'Enseignement Supérieur et de la Recherche of France (MESR) | Société Française d'Hématologie (SFH)

Authors: Brice Lagrange, Romain Z. Martin, Nathalie Droin, Romain Aucagne, Jérôme Paggetti, Anne Largeot, Raphaël Itzykson, Eric Solary, Laurent Delva, Jean-Noël Bastie