The interplay of IKK, NF-κB and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation

Journal Article published May 2017 in Immunological Reviews volume 277 issue 1 on pages 113 to 127

Research funded by European Research Council (323040) | Deutsche Forschungsgemeinschaft (SPP1656SFB829SFB1218SFB670) | European Commission (223404) | Deutsche Krebshilfe (110302) | Worldwide Cancer Research (15-0228) | Helmholtz Alliance Preclinical Comprehensive Cancer Center

Authors: Vangelis Kondylis, Snehlata Kumari, Katerina Vlantis, Manolis Pasparakis

Intrinsic regulation of enteroendocrine fate by Numb

Journal Article published 3 Jul 2017 in The EMBO Journal volume 36 issue 13 on pages 1928 to 1945

Research funded by Worldwide Cancer Research | Ligue Contre le Cancer | Fondation ARC pour la Recherche sur le Cancer | Agence Nationale de la Recherche | Labex (ANR‐11‐LBX‐0044)

Authors: Jérémy Sallé, Louis Gervais, Benjamin Boumard, Marine Stefanutti, Katarzyna Siudeja, Allison J Bardin

Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry

Journal Article published 15 Jan 2017 in Clinical Cancer Research volume 23 issue 2 on pages 387 to 398

Research funded by Knight-Wallace Fellows, University of Michigan (UVA2011-4969 and UVA2014-7245) | Worldwide Cancer Research (14-1164) | Maag Lever Darm Stichting (MLDS-CDG 14-03) | H2020 European Research Council (ERG-StG 638193) | Cancer Research UK (C14303/A17197 and A19274)

Authors: Anne Trinh, Kari Trumpi, Felipe De Sousa E Melo, Xin Wang, Joan H. de Jong, Evelyn Fessler, Peter J.K. Kuppen, Marlies S. Reimers, Marloes Swets, Miriam Koopman, Iris D. Nagtegaal, Marnix Jansen, Gerrit K.J. Hooijer, George J.A. Offerhaus, Onno Kranenburg, Cornelis J. Punt, Jan Paul Medema, Florian Markowetz, Louis Vermeulen

SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice

Journal Article published 16 Feb 2021 in Proceedings of the National Academy of Sciences volume 118 issue 7 on page e2017115118

Research funded by Medical Research Council (FC001107U117562207U117570590U1175512772) | Cancer Research UK (FC001107) | Wellcome Trust (FC001107) | Worldwide Cancer Research (13-1270)

Authors: Veronica Moncho-Amor, Probir Chakravarty, Christophe Galichet, Ander Matheu, Robin Lovell-Badge, Karine Rizzoti

Matrix-Targeting Immunotherapy Controls Tumor Growth and Spread by Switching Macrophage Phenotype

Journal Article published Mar 2020 in Cancer Immunology Research volume 8 issue 3 on pages 368 to 382

Research funded by Worldwide Cancer Research (14-1070) | Medical Research Council | Ligue Contre le Cancer (LNCC) | China Scholarship Council (fellowship) | Versus Arthritis (20003) | Nascient Ltd | Kennedy Trust for Rheumatology Research | The Austrian Science Fund (J-4102) | Institut National contre le Cancer (INCA/TENPLAMET) | ARC (fellowship) | Conacyt Mexico (fellowship) | French Ministry of Research (fellowship) | Clarendon Fund Scholarship

Authors: Claire Deligne, Devadarssen Murdamoothoo, Anís N. Gammage, Martha Gschwandtner, William Erne, Thomas Loustau, Anna M. Marzeda, Raphael Carapito, Nicodème Paul, Inés Velazquez-Quesada, Imogen Mazzier, Zhen Sun, Gertraud Orend, Kim S. Midwood

Cancer-associated thrombosis: The search for the holy grail continues

Journal Article published Oct 2018 in Research and Practice in Thrombosis and Haemostasis volume 2 issue 4 on pages 622 to 629

Research funded by KWF Kankerbestrijding (UL 2015-7594) | Worldwide Cancer Research (WWCR 15-1186)

Authors: Betül Ünlü, Henri H. Versteeg

Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer’s Disease

Journal Article published 11 Apr 2019 in ACS Medicinal Chemistry Letters volume 10 issue 4 on pages 469 to 474

Research funded by FP7 Health (282510) | Worldwide Cancer Research (15-1002) | Ministero dell’Istruzione, dell’Università e della Ricerca (20152TE5PK) | Associazione Italiana per la Ricerca sul Cancro (17217) | Università di Bologna | Consiglio Nazionale delle Ricerche | European Cooperation in Science and Technology (CM1406)

Authors: Angela De Simone, Valeria La Pietra, Nibal Betari, Nicola Petragnani, Mariarosaria Conte, Simona Daniele, Deborah Pietrobono, Claudia Martini, Sabrina Petralla, Raffaella Casadei, Lara Davani, Flavia Frabetti, Pasquale Russomanno, Ettore Novellino, Serena Montanari, Vincenzo Tumiatti, Patrizia Ballerini, Federica Sarno, Angela Nebbioso, Lucia Altucci, Barbara Monti, Vincenza Andrisano, Andrea Milelli

Differing roles of CD1d2 and CD1d1 proteins in type I natural killer T cell development and function

Journal Article published 6 Feb 2018 in Proceedings of the National Academy of Sciences volume 115 issue 6 on pages E1204 to E1213

Research funded by National Institute of Allergy and Infectious Diseases (AI124076AI121761) | American Association of Immunologists (25A4174) | Department of Health | National Health and Medical Research Council (WWCR-16-1106) | Worldwide Cancer Research (16-1106) | ARC | Centre of Excellence for Coherent X-Ray Science, Australian Research Council (FT160100074FL160100049)

Authors: Srinivasan Sundararaj, Jingjing Zhang, S. Harsha Krovi, Romain Bedel, Kathryn D. Tuttle, Natacha Veerapen, Gurdyal S. Besra, Yogesh Khandokar, T. Praveena, Jérôme Le Nours, Jennifer L. Matsuda, Jamie Rossjohn, Laurent Gapin

Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model

Journal Article published Mar 2021 in Journal for ImmunoTherapy of Cancer volume 9 issue 3 on page e001963

Research funded by Mater Foundation | Worldwide Cancer Research (15-0181) | National Health and Medical Research Council (1078987)

Authors: Yoke Seng Lee, Liam J O'Brien, Carina M Walpole, Frances E Pearson, Ingrid M Leal-Rojas, Kelly-Anne Masterman, Victoria Atkinson, Andrew Barbour, Kristen J Radford

UPR: An Upstream Signal to EMT Induction in Cancer

Journal Article published 8 May 2019 in Journal of Clinical Medicine volume 8 issue 5 on page 624

Research funded by Instituto de Salud Carlos III (CIBERONC 16/12/00295) | Worldwide Cancer Research (AICR-12-1057 and WWCR-16-0295)

Authors: Patricia G. Santamaría, María J. Mazón, Pilar Eraso, Francisco Portillo