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Ajinomoto Pharmaceuticals
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Multicenter, randomized, open-label Phase II study comparing S-1 alternate-day oral therapy with the standard daily regimen as a first-line treatment in patients with unresectable advanced pancreatic cancer

Journal Article published 1 Mar 2017 in Cancer Chemotherapy and Pharmacology volume 79 issue 4 on pages 813 to 823

Research funded by Taiho Pharmaceutical | Kyowa Hakko Kirin | Ajinomoto Pharmaceuticals | Otsuka Pharmaceutical | Mochida Pharmaceutical Company | Daiichi-Sankyo

Authors: Hiroki Yamaue, Atsushi Shimizu, Yasuhiro Hagiwara, Masayuki Sho, Hiroaki Yanagimoto, Shoji Nakamori, Hideki Ueno, Hiroshi Ishii, Masayuki Kitano, Kazuya Sugimori, Hiroyuki Maguchi, Shinichi Ohkawa, Hiroshi Imaoka, Daisuke Hashimoto, Kazuki Ueda, Hiroko Nebiki, Tatsuya Nagakawa, Hiroyuki Isayama, Isao Yokota, Yasuo Ohashi, Tetsuhiko Shirasaka

Nontargeted LC–MS Metabolomics Approach for Metabolic Profiling of Plasma and Urine from Pigs Fed Branched Chain Amino Acids for Maximum Growth Performance

Journal Article published 7 Nov 2016 in Journal of Proteome Research volume 15 issue 12 on pages 4195 to 4207

Research funded by Aarhus Universitet | Ajinomoto Pharmaceuticals | Teknologi og Produktion, Det Frie Forskningsråd

Authors: Elham A. Soumeh, Mette S. Hedemann, Hanne D. Poulsen, Etienne Corrent, Jacob van Milgen, Jan V. Nørgaard

A plant effector‐triggered immunity signaling sector is inhibited by pattern‐triggered immunity

Journal Article published 15 Aug 2017 in The EMBO Journal volume 36 issue 18 on pages 2758 to 2769

Research funded by National Science Foundation (IOS‐1121425, MCB‐1518058, IOS‐1025642, IOS‐1353854) | Ajinomoto Pharmaceuticals

Authors: Noriyuki Hatsugai, Daisuke Igarashi, Keisuke Mase, You Lu, Yayoi Tsuda, Suma Chakravarthy, Hai‐Lei Wei, Joseph W Foley, Alan Collmer, Jane Glazebrook, Fumiaki Katagiri

Effects of ramelteon on cardiac injury and adipose tissue pathology in rats with metabolic syndrome

Journal Article published 15 Mar 2018 in Annals of the New York Academy of Sciences volume 1421 issue 1 on pages 73 to 87

Research funded by Prof. Makoto Hirai (an unrestricted grant) | Ajinomoto Pharmaceuticals (an unrestricted grant) | Prof. Kohzo Nagata (an unrestricted grant) | EA Pharma Co. Ltd. (Tokyo, Japan) (an unrestricted grant) | Mr. Kunihiko Sugimoto (an unrestricted grant) | Dr. Tomohisa Itosu (an unrestricted grant) | Suzuken Memorial Foundation (2015 Research Fund)

Authors: Ayako Uchinaka, Yuri Kawashima, Yuki Sano, Shogo Ito, Yusuke Sano, Kai Nagasawa, Natsumi Matsuura, Mamoru Yoneda, Yuichiro Yamada, Toyoaki Murohara, Kohzo Nagata

The relationship between a blunted morning surge and a reversed nocturnal blood pressure dipping or “riser” pattern

Journal Article published 20 Aug 2017 in The Journal of Clinical Hypertension volume 19 issue 11 on pages 1108 to 1114

Research funded by Ajinomoto Pharmaceuticals | Mochida Pharmaceutical Company

Authors: Takeshi Fujiwara, Naoko Tomitani, Keiko Sato, Ayako Okura, Noriyuki Suzuki, Kazuomi Kario

The effects of estrogen and progesterone on plasma amino acids levels: evidence from change plasma amino acids levels during the menstrual cycle in women

Journal Article published 30 Oct 2018 in Biological Rhythm Research on pages 1 to 14

Research funded by Ajinomoto Pharmaceuticals

Authors: Asuka Sawai, Kayoko Tsuzuki, Masamitsu Yamauchi, Noriko Kimura, Toshiki Tsushima, Kana Sugiyama, Yumiko Ota, Shinya Sawai, Osamu Tochikubo

Variable-Intensity Simulated Team-Sport Exercise Increases Daily Protein Requirements in Active Males

Journal Article published 21 Dec 2017 in Frontiers in Nutrition volume 4

Research funded by Ajinomoto Pharmaceuticals

Authors: Jeffrey E. Packer, Denise J. Wooding, Hiroyuki Kato, Glenda Courtney-Martin, Paul B. Pencharz, Daniel R. Moore

Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial

Journal Article published Oct 2017 in The Lancet volume 390 issue 10106 on pages 1949 to 1961

Research funded by Clovis Oncology | AbbVie | American Association for Cancer Research | EMD Serono | Millennium | U.S. Department of Defense (OC120506) | Ergomed | Janssen Biotech | GamaMabs and Merus | VentiRx | Immunogen | Ovarian Cancer Research Fund | Array BioPharma | OncoMed Pharmaceutical | Genentech | V Foundation Translational Award | Stand Up To Cancer | Memorial Sloan-Kettering Cancer Center (P30 CA008748) | Roche | Janssen | AstraZeneca | Ajinomoto Pharmaceuticals | Esperance | Merck | Amgen | National Ovarian Cancer Coalition (SU2C-AACR-DT16–15) | Regeneron Pharmaceuticals | Experimental Cancer Medicine Centres at Glasgow | University College London

Authors: Robert L Coleman, Amit M Oza, Domenica Lorusso, Carol Aghajanian, Ana Oaknin, Andrew Dean, Nicoletta Colombo, Johanne I Weberpals, Andrew Clamp, Giovanni Scambia, Alexandra Leary, Robert W Holloway, Margarita Amenedo Gancedo, Peter C Fong, Jeffrey C Goh, David M O'Malley, Deborah K Armstrong, Jesus Garcia-Donas, Elizabeth M Swisher, Anne Floquet, Gottfried E Konecny, Iain A McNeish, Clare L Scott, Terri Cameron, Lara Maloney, Jeff Isaacson, Sandra Goble, Caroline Grace, Thomas C Harding, Mitch Raponi, James Sun, Kevin K Lin, Heidi Giordano, Jonathan A Ledermann, M Buck, A Dean, M L Friedlander, J C Goh, P Harnett, G Kichenadasse, C L Scott, H Denys, L Dirix, I Vergote, L Elit, P Ghatage, A M Oza, M Plante, D Provencher, J I Weberpals, S Welch, A Floquet, L Gladieff, F Joly, A Leary, A Lortholary, J Lotz, J Medioni, O Tredan, B You, A El-Balat, C Hänle, P Krabisch, T Neunhöffer, M Pölcher, P Wimberger, A Amit, S Kovel, M Leviov, T Safra, R Shapira-Frommer, S Stemmer, A Bologna, N Colombo, D Lorusso, S Pignata, R F Sabbatini, G Scambia, S Tamberi, C Zamagni, P C Fong, A O'Donnell, M Amenedo Gancedo, A Casado Herraez, J Garcia-Donas, E M Guerra, A Oaknin, I Palacio, I Romero, A Sanchez, S N Banerjee, A Clamp, Y Drew, H G Gabra, D Jackson, J A Ledermann, I A McNeish, C Parkinson, M Powell, C Aghajanian, D K Armstrong, M J Birrer, M K Buss, S K Chambers, L-m Chen, R L Coleman, R W Holloway, G E Konecny, L Ma, M A Morgan, R T Morris, D G Mutch, D M O'Malley, B M Slomovitz, E M Swisher, T Vanderkwaak, M Vulfovich

Surveillance for dysplasia in patients with ulcerative colitis: Discrepancy between guidelines and practice

Journal Article published 15 Mar 2017 in Digestive Endoscopy volume 29 issue 5 on pages 584 to 593

Research funded by Mitsubishi Tanabe Pharma Co., Ltd | Ono Pharmaceutical Co., Ltd | AbbVie | Daiichi-Sankyo | Nippon Kayaku Co. Ltd | Otsuka Pharma Co., Ltd | Takeda Pharmaceutical Company | Zeria Pharmaceutical Co. Ltd | Gene Care Research Institute Co., Ltd | JIMRO Co. Ltd | Eisai Co. Ltd | Asahi Kasei Kuraray Medical Co, Ltd | Kyowa Hakko Kirin Co., Ltd | Ajinomoto Pharmaceuticals | Astellas Pharma US | UCB Japan Co., Ltd

Authors: Masaru Shinozaki, Kiyonori Kobayashi, Reiko Kunisaki, Tadakazu Hisamatsu, Makoto Naganuma, Ken-ichi Takahashi, Yasushi Iwao, Yasuo Suzuki, Mamoru Watanabe, Michio Itabashi, Akira Torii, Masakazu Takazoe, Akira Sugita

The role of α4 integrin in Theiler’s murine encephalomyelitis virus (TMEV)-induced demyelinating disease: an infectious animal model for multiple sclerosis (MS)

Journal Article published 1 Nov 2016 in International Immunology volume 28 issue 12 on pages 575 to 584

Research funded by Health and Labor Sciences Research | Ministry of Health, Labor and Welfare of Japan | Terumo Lifescience Foundation | Ajinomoto Pharmaceuticals (HCA3551)

Authors: Yuta Hirano, Kunitoshi Kobayashi, Hiroki Tomiki, Yuhji Inaba, Motoki Ichikawa, Byung S. Kim, Chang-Sung Koh