Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies

JOURNAL ARTICLE published October 2021 in European Journal of Medicinal Chemistry

Research funded by Canadian Institutes of Health Research (COVID-19 SOF-549297-2019,VR3-172655)

Authors: Wayne Vuong | Conrad Fischer | Muhammad Bashir Khan | Marco J. van Belkum | Tess Lamer | Kurtis D. Willoughby | Jimmy Lu | Elena Arutyunova | Michael A. Joyce | Holly A. Saffran | Justin A. Shields | Howard S. Young | James A. Nieman | D. Lorne Tyrrell | M. Joanne Lemieux | John C. Vederas