Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation

JOURNAL ARTICLE published August 2019 in Journal of Biological Chemistry

Research funded by MEXT | Japan Society for the Promotion of Science (JSPS) (26290019,JP16H06277) | JST | Precursory Research for Embryonic Science and Technology (PRESTO) (110650) | Japan Agency for Medical Research and Development (AMED) (JP18dm027001) | HHS | National Institutes of Health (NIH) (AG10124,AG 17586)

Authors: Takashi Saito | Naomi Mihira | Yukio Matsuba | Hiroki Sasaguri | Shoko Hashimoto | Sneha Narasimhan | Bin Zhang | Shigeo Murayama | Makoto Higuchi | Virginia M.Y. Lee | John Q. Trojanowski | Takaomi C. Saido