Hypoglycaemic and hypolipidemic effect of different solvents extract of unripe Carica papaya seed in streptozotocin-induced diabetic rats

JOURNAL ARTICLE published 30 January 2028 in International Journal of Science and Research Archive

Antioxidant, antidiabetic, neuroprotective, and phytochemical evaluation of Chenopodium ambrosioides ethanol extract

JOURNAL ARTICLE published 30 December 2024 in Journal of Medicine and Health Studies

Authors: Reem Alhasani

Computational design of α-amylase from Bacillus licheniformis to increase its activity and stability at high temperatures

JOURNAL ARTICLE published December 2024 in Computational and Structural Biotechnology Journal

Authors: Shuai Fan | Xudong Lü | Xiyu Wei | Ruijie Lü | Cuiyue Feng | Yuanyuan Jin | Maocai Yan | Zhaoyong Yang

Assessment of Anticholinergic and Antidiabetic Properties of Some Natural and Synthetic Molecules: An In vitro and In silico Approach

JOURNAL ARTICLE published October 2024 in Current Computer-Aided Drug Design

Authors: Veysel Çomaklı | İmdat Aygül | Rüya Sağlamtaş | Müslüm Kuzu | Ramazan Demirdağ | Hülya Akincioğlu | Şevki Adem | İlhami Gülçin

Purification and characterization of betacyanin monomers from Hylocereus polyrhizus peel: A comparative study of their antioxidant and antidiabetic activities with mechanistic insights

JOURNAL ARTICLE published September 2024 in Food Chemistry

Authors: Xiaojuan Xu | Yingfen Jiang | Qi Xuan Yeo | Weibiao Zhou

The potential of glucosidase and glucose oxidase for aroma improvement in concentrated peach puree based on volatilomics and metabolomics

JOURNAL ARTICLE published August 2024 in Food Chemistry

Authors: Gege Liu | Qinqin Chen | Min Gou | Jinfeng Bi

Exploring the composition and properties of Centella asiatica metabolites and investigating their impact on BSA glycation, LDL oxidation and α-amylase inhibition

JOURNAL ARTICLE published August 2024 in Journal of Pharmaceutical and Biomedical Analysis

Research funded by Fundação de Amparo à Pesquisa do Estado de Minas Gerais (APQ-01981-16,APQ-01856-14,APQ-01612-18,PPM 00503-18,312812/2021-3) | Conselho Nacional de Desenvolvimento Científico e Tecnológico (465669/2014-0)

Authors: Ana Luiza Silva Borges | Vinícius Prado Bittar | Allisson Benatti Justino | Maria Sol Peña Carrillo | Rener Francisco Mateus Duarte | Nagela Bernadelli Sousa Silva | Daniela Silva Gonçalves | Diego Godina Prado | Iasmin Aparecida Cunha Araújo | Mário Machado Martins | Larissa Campos Motta | Carlos Henrique Gomes Martins | Françoise Vasconcelos Botelho | Neide Maria Silva | Alberto de Oliveira | Wanderson Romão | Foued Salmen Espíndola

Efficient biotransformation of naringenin to naringenin α-glucoside, a novel α-glucosidase inhibitor, by amylosucrase from Deinococcus wulumuquiensis

JOURNAL ARTICLE published August 2024 in Food Chemistry

Authors: Su-Jeong Yu | Yun-Sang So | Changjin Lim | Chi Heung Cho | Sang-Gil Lee | Sang-Ho Yoo | Cheon-Seok Park | Byung-Hoo Lee | Kyung Hyun Min | Dong-Ho Seo

Medicinal plants of Southeast Asia with anti-α-glucosidase activity as potential source for Type-2 diabetes mellitus treatment

JOURNAL ARTICLE published August 2024 in Journal of Ethnopharmacology

Authors: Mohammad Amil Zulhilmi Benjamin | Ruzaidi Azli Mohd Mokhtar | Mohammad Iqbal | Azmahani Abdullah | Roro Azizah | Lilis Sulistyorini | Nurkhasanah Mahfudh | Zainul Amiruddin Zakaria

Synthesis, anti-α-glucosidase activity, inhibition interaction, and anti-diabetic activity of novel cryptolepine derivatives

JOURNAL ARTICLE published August 2024 in Journal of Molecular Structure

Authors: Mei Feng | Bingwen Liang | Jinping Sun | Xiaofeng Min | Shao-Hua Wang | Yujing Lu | Xuetao Xu

Benzothiazole based sulfonamide scaffolds as active inhibitors of alpha-Amylase and alpha-glucosidase; synthesis, structure confirmation, In Silico molecular docking and ADME analysis

JOURNAL ARTICLE published August 2024 in Journal of Molecular Structure

Authors: Tayyiaba Iqbal | Shoaib Khan | Fazal Rahim | Rafaqat Hussain | Yousaf Khan | Shifa Felemban | M.M. Khowdiary

Inhibitory mechanism of arabinoxylan and β-glucan from hull-less barley on α-amylase activity: A comparison study

JOURNAL ARTICLE published August 2024 in Food Hydrocolloids

Authors: Hui Zhang | Zhipeng Li | Fan Xie | Guangqiang Wang | Zibo Song | Lianzhong Ai

Synthesis and biological (in vitro and in silico) screening of the 4-aryl-fused pyranopyrazole derivatives as enzyme (α-amylase, α-glucosidase, acetylcholinesterase & proteinase) inhibitors with anti-oxidant and cytotoxic activities

JOURNAL ARTICLE published August 2024 in Journal of Molecular Structure

Authors: Nagwa M. Abdelazeem | Wael Mahmoud Aboulthana | Zeinab A. Elshahid | Marwa El-Hussieny | Aisha A.K. Al-Ashmawy

Retrogradation inhibition of starches in staple foods with maltotetraose-forming amylase

JOURNAL ARTICLE published August 2024 in Food Chemistry

Authors: Yunlong Cui | Xueting Li | Dengyue Sun | Li Guo | Bo Cui | Feixue Zou | Jinpeng Wang | Chunrui Sun

1,2,3-Triazole-based betulinic acid derivatives as α-glucosidase inhibitors: Synthesis and in vitro and in vivo biological evaluation

JOURNAL ARTICLE published August 2024 in Journal of Molecular Structure

Authors: Yufei Zhang | Jiangyi Li | Xiaofeng Min | Bingwen Liang | Jinping Sun | Keyin Lin | Zhuang Xiong | Xuetao Xu | Wen-Hua Chen

Exploring the anti-inflammatory, sedative, antidiabetic, and antioxidant potential in in-vitro and in-vivo models and phenolic profiling of Atractylis aristata Batt.

JOURNAL ARTICLE published August 2024 in Journal of Ethnopharmacology

Authors: Asma Abid | Zahnit Wafa | Mahdi Belguidoum | Tatou Touahria | Nour Elhouda Mekhadmi | Messaouda Dekmouche | Lazhar Bechki | Kamilia Bireche | Walid Boussebaa | Ammar AL-Farga

Indolyl imine compounds as multi-target agents; synthesis, antidiabetic, anticholinesterase, antioxidant activities and molecular modeling

JOURNAL ARTICLE published August 2024 in Journal of Molecular Structure

Research funded by Gebze Technical University (2021-A101-04)

Authors: Sadık M. Ceyhan | İrem Nur Zengin | Murat Bingul | Hasan Sahin | Mehmet Boga | Mehmet F. Saglam | Hakan Kandemir | Ibrahim F. Sengul

Chemical stability of carboxylpyranocyanidin-3-O-glucoside under β-glucosidase treatment and description of their interaction

JOURNAL ARTICLE published July 2024 in Food Chemistry

Authors: Kailan Yuan | Xusheng Li | Yingyu Zeng | Chuqi Liu | Yuanqin Zhu | Jun Hu | Jianxia Sun | Weibin Bai

Sensitive and label-free SPR biosensing platforms for high-throughput screening of plasma membrane receptors interactions with insulin-like targets of hypoglycaemic activity

JOURNAL ARTICLE published July 2024 in Talanta

Authors: Marcin Drozd | Ewa Kobylska | Małgorzata Żmieńko | Michał Chudy

In silico studies of Ruellia tuberosa L. compounds as aldose reductase, dipeptidyl peptidase 4, and α-glucosidase inhibitors against type 2 diabetes mellitus

JOURNAL ARTICLE published 1 July 2024 in Journal of Pharmacy & Pharmacognosy Research

Authors: Ekowati Retnaningtyas | Andri Setiawan | Budi Susatia | Tanto Hariyanto | Ni Luh Putu Eka Sudiwati