Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity

JOURNAL ARTICLE published 22 June 2020 in Journal of Clinical Investigation

Research funded by Deutsche Forschungsgemeinschaft (SI 2087/2-1)

Authors: Joe J. Simon | Marion A. Stopyra | Esther Mönning | Sebastian Sailer | Nora Lavandier | Lars P. Kihm | Martin Bendszus | Hubert Preissl | Wolfgang Herzog | Hans-Christoph Friederich

Human NLRC4 promotes cancer survival and is associated to type-I interferon signaling and immune infiltration

JOURNAL ARTICLE published 23 April 2024 in Journal of Clinical Investigation

Research funded by NIH NIA (1P01AG066591-01A1.)

Authors: Charlotte Domblides | Steven Crampton | Hong Liu | Juliet M. Bartleson | Annie Nguyen | Claudia Champagne | Emily E. Landy | Lindsey Spiker | Christopher Proffitt | Sunil Bhattarai | Anissa P. Grawe | Matias Fuentealba Valenzuela | Lydia Lartigue | Isabelle Mahouche | Jeremy Dupaul-Chicoine | Kazuho Nishimura | Félix Lefort | Marie Decraecker | Valérie Velasco | Sonia Netzer | Vincent Pitard | Christian Roy | Isabelle Soubeyran | Victor Racine | Patrick Blanco | Julie Déchanet-Merville | Maya Saleh | Scott W. Canna | David Furman | Benjamin Faustin

Identification of SARS-CoV-2–specific immune alterations in acutely ill patients

JOURNAL ARTICLE published 15 April 2021 in Journal of Clinical Investigation

Research funded by CIHR/CITF (VR2-173203)

Authors: Rose-Marie Rébillard | Marc Charabati | Camille Grasmuck | Abdelali Filali-Mouhim | Olivier Tastet | Nathalie Brassard | Audrey Daigneault | Lyne Bourbonnière | Sai Priya Anand | Renaud Balthazard | Guillaume Beaudoin-Bussières | Romain Gasser | Mehdi Benlarbi | Ana Carmena Moratalla | Yves Carpentier Solorio | Marianne Boutin | Negar Farzam-kia | Jade Descôteaux-Dinelle | Antoine Philippe Fournier | Elizabeth Gowing | Annemarie Laumaea | Hélène Jamann | Boaz Lahav | Guillaume Goyette | Florent Lemaître | Victoria Hannah Mamane | Jérémie Prévost | Jonathan Richard | Karine Thai | Jean-François Cailhier | Nicolas Chomont | Andrés Finzi | Michaël Chassé | Madeleine Durand | Nathalie Arbour | Daniel E. Kaufmann | Alexandre Prat | Catherine Larochelle

SARS-CoV-2 mRNA vaccination–induced immunological memory in human nonlymphoid and lymphoid tissues

JOURNAL ARTICLE published 15 December 2023 in Journal of Clinical Investigation

Research funded by Deutsche Forschungsgemeinschaft (KO-2270/7-1) | Deutsche Forschungsgemeinschaft (KO-2270/4-1) | Deutsche Forschungsgemeinschaft (KO-2270/8-1) | Wilhelm-Sander Stiftung (2022.035.1) | Zentrales Innovationsprogramm Mittelstand (KK5463201BA2) | Chiesi GmbH (n/a) | Charité Clinician Scientist Program funded by the Charité–Universitätsmedizin Berlin and the Berlin Institute of Health (n/a) | German Ministry for Education and Research (01ZZ2001) | Ministry for Science, Research, and Arts of Baden-Württemberg, Germany and the European Commission (101015756)

Authors: Vanessa Proß | Arne Sattler | Sören Lukassen | Laura Tóth | Linda Marie Laura Thole | Janine Siegle | Carolin Stahl | An He | Georg Damm | Daniel Seehofer | Christina Götz | Christian Bayerl | Pia Jäger | Alexander Macke | Stephan Eggeling | Bernadette Kirzinger | Thomas Mayr | Hermann Herbst | Katharina Beyer | Dominik Laue | Jan Krönke | Jan Braune | Friederike Rosseck | Beatrice Kittner | Frank Friedersdorff | Mandy Hubatsch | Sarah Weinberger | Nils Lachmann | Veit Maria Hofmann | Eva Schrezenmeier | Carolin Ludwig | Hubert Schrezenmeier | Katharina Jechow | Christian Conrad | Katja Kotsch

Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction

JOURNAL ARTICLE published 2 May 2017 in Journal of Clinical Investigation

Authors: Christa F. Gaskill | Erica J. Carrier | Jonathan A. Kropski | Nathaniel C. Bloodworth | Swapna Menon | Robert F. Foronjy | M. Mark Taketo | Charles C. Hong | Eric D. Austin | James D. West | Anna L. Means | James E. Loyd | W. David Merryman | Anna R. Hemnes | Stijn De Langhe | Timothy S. Blackwell | Dwight J. Klemm | Susan M. Majka

A randomized controlled experimental medicine study of ghrelin in value-based decision making

JOURNAL ARTICLE published 15 June 2023 in Journal of Clinical Investigation

Research funded by Swedish Research Council (2013-07434) | Marcus and Marianne Wallenberg foundation (2014.0187)

Authors: Michal Pietrzak | Adam Yngve | J. Paul Hamilton | Robin Kämpe | Rebecca Boehme | Anna Asratian | Emelie Gauffin | Andreas Löfberg | Sarah Gustavson | Emil Persson | Andrea J. Capusan | Lorenzo Leggio | Irene Perini | Gustav Tinghög | Markus Heilig

Altered immune cell follicular dynamics in HIV infection following influenza vaccination

JOURNAL ARTICLE published 2 July 2018 in Journal of Clinical Investigation

Research funded by National Institutes of Health (Intramural Research Program,Vaccine Research Center,NIAID,NIH) | NIH (R56AI106718)

Authors: Eirini Moysi | Suresh Pallikkuth | Leslie R. De Armas | Louis E. Gonzalez | David Ambrozak | Varghese George | David Huddleston | Rajendra Pahwa | Richard A. Koup | Constantinos Petrovas | Savita Pahwa

Trim the gut, lose the weight — and the bone

JOURNAL ARTICLE published 6 May 2019 in Journal of Clinical Investigation

Authors: Soravis Osataphan | Mary Elizabeth Patti

Omicron infection elicits a broad neutralizing response in hospitalized patients with COVID-19

JOURNAL ARTICLE published 1 December 2022 in Journal of Clinical Investigation

Authors: Elizabeth M. McNally

Removing uncertainty from variants of unknown significance

JOURNAL ARTICLE published 15 June 2023 in Journal of Clinical Investigation

Authors: Elizabeth M. McNally

Imaging infection amid inflammation

JOURNAL ARTICLE published 15 September 2022 in Journal of Clinical Investigation

Authors: Patrick C. Seed

Viewing both sides of the coin for infectious disease diagnosis

JOURNAL ARTICLE published 17 April 2023 in Journal of Clinical Investigation

Authors: Fiona R. Strouts | Linda B. McAllister | Ephraim L. Tsalik

CDK4 is an essential insulin effector in adipocytes

JOURNAL ARTICLE published 1 July 2022 in Journal of Clinical Investigation

Authors: Sylviane Lagarrigue | Isabel C. Lopez-Mejia | Pierre-Damien Denechaud | Xavier Escoté | Judit Castillo-Armengol | Veronica Jimenez | Carine Chavey | Albert Giralt | Qiuwen Lai | Lianjun Zhang | Laia Martinez-Carreres | Brigitte Delacuisine | Jean-Sébastien Annicotte | Emilie Blanchet | Sébastien Huré | Anna Abella | Francisco J. Tinahones | Joan Vendrell | Pierre Dubus | Fatima Bosch | C. Ronald Kahn | Lluis Fajas

Richard Hynes, Erkki Ruoslahti, and Timothy Springer receive Lasker prize for pioneering work on integrins

JOURNAL ARTICLE published 28 September 2022 in Journal of Clinical Investigation

Authors: Hidayatullah G. Munshi

Mitochondrial dysfunction reactivates α-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models

JOURNAL ARTICLE published 3 January 2023 in Journal of Clinical Investigation

Research funded by Canadian Institutes of Health Research (MOP16652)

Authors: Kimberly A. Jett | Zakery N. Baker | Amzad Hossain | Aren Boulet | Paul A. Cobine | Sagnika Ghosh | Philip Ng | Orhan Yilmaz | Kris Barreto | John DeCoteau | Karen Mochoruk | George N. Ioannou | Christopher Savard | Sai Yuan | Osama H.M.H. Abdalla | Christopher Lowden | Byung-Eun Kim | Hai-Ying Mary Cheng | Brendan J. Battersby | Vishal M. Gohil | Scot C. Leary

Introduction of Linda P. Fried, MD, MPH

JOURNAL ARTICLE published 15 December 2022 in Journal of Clinical Investigation

Authors: Anne B. Newman

CPR: cardiac phosphatase in resuscitation

JOURNAL ARTICLE published 1 May 2023 in Journal of Clinical Investigation

Authors: Arjun Deb

R-spondin 3 governs secretory differentiation in the gastric oxyntic glands

JOURNAL ARTICLE published 1 November 2022 in Journal of Clinical Investigation

Authors: Ken Kurokawa | Timothy C. Wang | Yoku Hayakawa

Ushering in the cardiac role of Ubiquilin1

JOURNAL ARTICLE published 22 October 2018 in Journal of Clinical Investigation

Authors: Xi Fang | Christa Trexler | Ju Chen

Inhibition of neogenin fosters resolution of inflammation and tissue regeneration

JOURNAL ARTICLE published 1 May 2019 in Journal of Clinical Investigation

Authors: Martin Schlegel | Andreas Körner | Torsten Kaussen | Urs Knausberg | Carmen Gerber | Georg Hansmann | Hulda Soffia Jónasdóttir | Martin Giera | Valbona Mirakaj