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Decreased Lung Tumor Development in SwAPP Mice through the Downregulation of CHI3L1 and STAT 3 Activity via the Upregulation of miRNA342-3p

JOURNAL ARTICLE published June 2019 in Molecular Therapy - Nucleic Acids

Research funded by Korean Government (MRC2017R1A5A2015541)

Authors: Dong Hun Lee | Ki Cheon Kim | Chul Ju Hwang | Kyung Ran Park | Young Suk Jung | Sun Young Kim | Ji Young Kim | Ju Kyung Song | Min Ji Song | Min Ki Choi | Dae Youn Hwang | Sang-Bae Han | Jin Tae Hong

https://doi.org/10.1016/j.omtn.2019.02.007 Actions

Virus-mediated Genetic Surgery: Homologous Recombination With a Little “Helper” From My Friends

JOURNAL ARTICLE published 2012 in Molecular Therapy - Nucleic Acids

Authors: Dieter C Gruenert | R Geoffrey Sargent

https://doi.org/10.1038/mtna.2011.7 Actions

miR675 Accelerates Malignant Transformation of Mesenchymal Stem Cells by Blocking DNA Mismatch Repair

JOURNAL ARTICLE published March 2019 in Molecular Therapy - Nucleic Acids

Research funded by National Natural Science Foundation of China (81572773,NCSF 81773158)

Authors: Yanan Lu | Shuting Song | Xiaoxue Jiang | Qiuyu Meng | Chen Wang | Xiaonan Li | Yuxin Yang | Xiaoru Xin | Qidi Zheng | Liyan Wang | Hu Pu | Xin Gui | Tianming Li | Dongdong Lu

https://doi.org/10.1016/j.omtn.2018.11.010 Actions

A Tumor-specific MicroRNA Recognition System Facilitates the Accurate Targeting to Tumor Cells by Magnetic Nanoparticles

JOURNAL ARTICLE published 2016 in Molecular Therapy - Nucleic Acids

Authors: Yingting Yu | Yi Yao | Hao Yan | Rui Wang | Zhenming Zhang | Xiaodan Sun | Lingyun Zhao | Xiang Ao | Zhen Xie | Qiong Wu

https://doi.org/10.1038/mtna.2016.28 Actions

Treatment of CHO cells with Taxol and reversine improves micronucleation and microcell-mediated chromosome transfer efficiency

JOURNAL ARTICLE published September 2023 in Molecular Therapy - Nucleic Acids

Authors: Narumi Uno | Hiroyuki Satofuka | Hitomaru Miyamoto | Kazuhisa Honma | Teruhiko Suzuki | Kyotaro Yamazaki | Ryota Ito | Takashi Moriwaki | Shusei Hamamichi | Kazuma Tomizuka | Mitsuo Oshimura | Yasuhiro Kazuki

https://doi.org/10.1016/j.omtn.2023.07.002 Actions

Knockdown of IGF-1R Triggers Viral RNA Sensor MDA5- and RIG-I-Mediated Mitochondrial Apoptosis in Colonic Cancer Cells

JOURNAL ARTICLE published June 2019 in Molecular Therapy - Nucleic Acids

Research funded by Natural Science Foundation of China (91629303,81673449/81872884) | Beijing Natural Science Foundation Program and Scientific Research Key Program of Beijing Municipal Commission of Education (KZ201710025020,KZ201810025033)

Authors: Shu-Qing Wang | Xiang-Yu Yang | Xin-Feng Yu | Shu-Xiang Cui | Xian-Jun Qu

https://doi.org/10.1016/j.omtn.2019.02.008 Actions

RNA nanoparticles for targeted therapies of triple-negative breast cancers

JOURNAL ARTICLE published September 2023 in Molecular Therapy - Nucleic Acids

Research funded by National Institute of General Medical Sciences (R35GM139587)

Authors: Leyla Danai | Eva Ge | Kirill A. Afonin

https://doi.org/10.1016/j.omtn.2023.08.013 Actions

miR-144-3p Suppresses Osteogenic Differentiation of BMSCs from Patients with Aplastic Anemia through Repression of TET2

JOURNAL ARTICLE published March 2020 in Molecular Therapy - Nucleic Acids

Research funded by National Natural Science Foundation of China (81470287) | Henan Outstanding Person Foundation of China (2018JR007)

Authors: Ning Li | Lina Liu | Yuzhang Liu | Suxia Luo | Yongping Song | Baijun Fang

https://doi.org/10.1016/j.omtn.2019.12.017 Actions

RANGE: Gene Transfer of Reversibly Controlled Polycistronic Genes

JOURNAL ARTICLE published 2013 in Molecular Therapy - Nucleic Acids

Authors: Yiwei Chen | Liji Cao | Chonglin Luo | Désirée AW Ditzel | Jörg Peter | Rolf Sprengel

https://doi.org/10.1038/mtna.2013.15 Actions

Multicellular Tumor Spheroids as a Model for Assessing Delivery of Oligonucleotides in Three Dimensions

JOURNAL ARTICLE published January 2014 in Molecular Therapy - Nucleic Acids

Authors: Kyle Carver | Xin Ming | Rudolph L Juliano

https://doi.org/10.1038/mtna.2014.5 Actions

Sustainable recovery of MBNL activity in autoregulatory feedback loop in myotonic dystrophy

JOURNAL ARTICLE published December 2022 in Molecular Therapy - Nucleic Acids

Authors: Zuzanna Rogalska | Krzysztof Sobczak

https://doi.org/10.1016/j.omtn.2022.10.023 Actions

Efficacy and safety of a SOD1-targeting artificial miRNA delivered by AAV9 in mice are impacted by miRNA scaffold selection

JOURNAL ARTICLE published December 2023 in Molecular Therapy - Nucleic Acids

Authors: Shukkwan K. Chen | Zachary C.E. Hawley | Maria I. Zavodszky | Sam Hana | Daniel Ferretti | Branka Grubor | Michael Hawes | Shanqin Xu | Stefan Hamann | Galina Marsh | Patrick Cullen | Ravi Challa | Thomas M. Carlile | Hang Zhang | Wan-Hung Lee | Andrea Peralta | Pete Clarner | Cong Wei | Kathryn Koszka | Feng Gao | Shih-Ching Lo

https://doi.org/10.1016/j.omtn.2023.102057 Actions

Nonviral Direct Conversion of Primary Mouse Embryonic Fibroblasts to Neuronal Cells

JOURNAL ARTICLE published 2012 in Molecular Therapy - Nucleic Acids

Authors: Andrew F Adler | Christopher L Grigsby | Karina Kulangara | Hong Wang | Ryohei Yasuda | Kam W Leong

https://doi.org/10.1038/mtna.2012.25 Actions

Circular RNA circPSD3 alleviates hepatic fibrogenesis by regulating the miR-92b-3p/Smad7 axis

JOURNAL ARTICLE published March 2021 in Molecular Therapy - Nucleic Acids

Authors: Fang-tian Bu | Yan Zhu | Xin Chen | Ao Wang | Ya-fei Zhang | Hong-mei You | Yang Yang | Ya-ru Yang | Cheng Huang | Jun Li

https://doi.org/10.1016/j.omtn.2021.01.007 Actions

cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice

JOURNAL ARTICLE published December 2022 in Molecular Therapy - Nucleic Acids

Authors: Wandi Zhu | Lai Wei | Chunhong Dong | Ye Wang | Joo Kim | Yao Ma | Gilbert X. Gonzalez | Bao-Zhong Wang

https://doi.org/10.1016/j.omtn.2022.10.024 Actions

Blockade of Inflammation and Apoptosis Pathways by siRNA Prolongs Cold Preservation Time and Protects Donor Hearts in a Porcine Model

JOURNAL ARTICLE published December 2017 in Molecular Therapy - Nucleic Acids

Research funded by Medicine Cross Fund of Shanghai Jiaotong University (YG2013MS35) | Natural Science Foundation of China (31572525,31270186)

Authors: Jia Wei | Shiyou Chen | Song Xue | Qiangru Zhu | Sha Liu | Li Cui | Xiuguo Hua | Yongyi Wang

https://doi.org/10.1016/j.omtn.2017.10.020 Actions

Dual Regulation of miR-34a and Notch Signaling in Triple-Negative Breast Cancer by Antibody/miRNA Nanocarriers

JOURNAL ARTICLE published September 2020 in Molecular Therapy - Nucleic Acids

Research funded by National Institutes of Health (R35GM119659)

Authors: Danielle M. Valcourt | Emily S. Day

https://doi.org/10.1016/j.omtn.2020.06.003 Actions

Liposome-mediated small RNA delivery to convert the macrophage polarity: A novel therapeutic approach to treat inflammatory uterine disease

JOURNAL ARTICLE published December 2022 in Molecular Therapy - Nucleic Acids

Authors: Mira Park | Hyeon-Ji Oh | Jieun Han | Seok-Ho Hong | Wooram Park | Haengseok Song

https://doi.org/10.1016/j.omtn.2022.11.018 Actions

Dose-dependent Toxicity of Humanized Renilla reniformis GFP (hrGFP) Limits Its Utility as a Reporter Gene in Mouse Muscle

JOURNAL ARTICLE published 2013 in Molecular Therapy - Nucleic Acids

Authors: Lindsay M Wallace | Andrew Moreo | K Reed Clark | Scott Q Harper

https://doi.org/10.1038/mtna.2013.16 Actions

Transcription Factor ELF1 Activates MEIS1 Transcription and Then Regulates the GFI1/FBW7 Axis to Promote the Development of Glioma

JOURNAL ARTICLE published March 2021 in Molecular Therapy - Nucleic Acids

Authors: Meixiong Cheng | Yi Zeng | Tian Zhang | Min Xu | Zhili Li | Yaqiu Wu

https://doi.org/10.1016/j.omtn.2020.10.015 Actions
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