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Biology drives the discovery of bispecific antibodies as innovative therapeutics

JOURNAL ARTICLE published 18 February 2020 in Antibody Therapeutics

Authors: Siwei Nie | Zhuozhi Wang | Maria Moscoso-Castro | Paul D'Souza | Can Lei | Jianqing Xu | Jijie Gu

Pan-cancer distribution of cleaved cell-surface amphiregulin, the target of the GMF-1A3 antibody drug conjugate

JOURNAL ARTICLE published 1 August 2022 in Antibody Therapeutics

Research funded by Department of Defense Breast Cancer Research Program (W81XWH-14-1-0294) | American Cancer Society (123001-RSG-12-267-01-TBE)

Authors: Kristopher A Lofgren | Nicolette C Reker | Sreeja Sreekumar | Paraic A Kenny

Enhancing antibody-dependent cell-mediated cytotoxicity: a strategy for improving antibody-based immunotherapy

JOURNAL ARTICLE published 31 August 2018 in Antibody Therapeutics

Research funded by National Institutes of Health (NCI CA511008,NCI CA50633)

Authors: David Zahavi | Dalal AlDeghaither | Allison O’Connell | Louis M Weiner

Developability assessment at early-stage discovery to enable development of antibody-derived therapeutics

JOURNAL ARTICLE published 18 January 2023 in Antibody Therapeutics

Authors: Weijie Zhang | Hao Wang | Nan Feng | Yifeng Li | Jijie Gu | Zhuozhi Wang

Strategies to mitigate the on- and off-target toxicities of recombinant immunotoxins: an antibody engineering perspective

JOURNAL ARTICLE published 1 August 2022 in Antibody Therapeutics

Authors: Mengyu Li | Sen Mei | Yi Yang | Yuelei Shen | Lei Chen

The emergence of AntibodyPlus: the future trend of antibody-based therapeutics

JOURNAL ARTICLE published 1 October 2022 in Antibody Therapeutics

Research funded by National Cancer Institute (ZIC BC011891,ZIA BC010891,Z01 BC010891)

Authors: Yong Zhu | Shawn Shouye Wang | Zhaohui Sunny Zhou | Mitchell Ho

An optimal antitumor response by a novel CEA/CD3 bispecific antibody for colorectal cancers

JOURNAL ARTICLE published 1 April 2021 in Antibody Therapeutics

Authors: Ninghai Wang | Harshal Patel | Irene C Schneider | Xin Kai | Avanish K Varshney | Li Zhou

Productivity and quality improvement for a symmetric bispecific antibody through the application of intensified perfusion cell culture

JOURNAL ARTICLE published 13 April 2022 in Antibody Therapeutics

Authors: Yongjun Qin | Rongmei Ma | Yang Li | Yifeng Li | Gong Chen | Weichang Zhou

Isolation of a human monoclonal antibody specific for the receptor binding domain of SARS-CoV-2 using a competitive phage biopanning strategy

JOURNAL ARTICLE published 30 April 2020 in Antibody Therapeutics

Research funded by Sichuan Science and Technology Program (2018RZ0019) | Science and Technology Department of Sichuan Province (CYHX202032,JL2020C-01)

Authors: Xin Zeng | Lingfang Li | Jing Lin | Xinlei Li | Bin Liu | Yang Kong | Shunze Zeng | Jianhua Du | Huahong Xiao | Tao Zhang | Shelin Zhang | Jianghai Liu

Rational design of peptides for identification of linear epitopes and generation of neutralizing monoclonal antibodies against DKK2 for cancer therapy

JOURNAL ARTICLE published 30 April 2020 in Antibody Therapeutics

Research funded by National Institutes of Health (CA214703,GM112182) | Chinese Ministry of Science and Technology (2014 14C2621110037)

Authors: Rongqing Zhao | Qian Xiao | Maohua Li | Wenlin Ren | Chenxi Xia | Xudong Liu | Yingzi Li | Tan Tan | Dianqing Wu | Le Sun

Erratum

JOURNAL ARTICLE published 1 January 2019 in Antibody Therapeutics

Next-Generation Antibody Therapeutics: Discovery, Development and Beyond: highlights of the third annual conference of the Chinese Antibody Society

JOURNAL ARTICLE published 1 October 2019 in Antibody Therapeutics

Authors: Hongyu Zhang | Mi Deng | Fen Pei | Shouye Wang | Mitchell Ho

Role of harvest depth filtration in controlling product-related impurities for a bispecific antibody

JOURNAL ARTICLE published 1 October 2022 in Antibody Therapeutics

Authors: Ehsan Espah Borujeni | Weixin Jin | Chun Shao | Naresh Chennamsetty | Xuankuo Xu | Sanchayita Ghose

Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML

JOURNAL ARTICLE published 16 January 2024 in Antibody Therapeutics

Research funded by National Center for Advancing Translational Sciences (TL1TR003169) | National Cancer Institute (R01CA248736,R01CA263079) | Department of Defense (ME190050) | Cancer Prevention and Research Institute of Texas (RP220032,RP150551) | Welch Foundation (AU-0042-20030616) | Immune-Onc Therapeutics, Inc. (#111077)

Authors: Joshua W Morse | Xun Gui | Mi Deng | Ryan Huang | Xiaohua Ye | Peng Zhao | Xuejun Fan | Wei Xiong | Chengcheng Zhang | Ningyan Zhang | Zhiqiang An

Antibody therapies for the treatment of COVID-19

JOURNAL ARTICLE published 30 April 2020 in Antibody Therapeutics

Research funded by Welch Foundation (AU-0042-20030616) | Cancer Prevention and Research Institute of Texas (RP150551,RP190561)

Authors: Zhiqiang Ku | Xiaohua Ye | Georgina To’a Salazar | Ningyan Zhang | Zhiqiang An

Targeting the cancer neoantigens p53 and KRAS with TCR mimic antibodies

JOURNAL ARTICLE published 8 October 2021 in Antibody Therapeutics

Research funded by Intramural Research Program of National Institutes of Health, NCI CCR Antibody Engineering Program (ZIC BC 011891)

Authors: Zhijian Duan | Mitchell Ho

Selectivity Conversion of Protease Inhibitory Antibodies

JOURNAL ARTICLE published 17 September 2018 in Antibody Therapeutics

Research funded by National Institutes of Health (1R01GM115672) | National Science Foundation (1453645)

Authors: Tyler Lopez | Aaron Ramirez | Chris Benitez | Zahid Mustafa | Henry Pham | Ramon Sanchez | Xin Ge

Induction of neutralizing antibodies by human papillomavirus vaccine generated in mammalian cells

JOURNAL ARTICLE published 5 April 2019 in Antibody Therapeutics

Research funded by National Science Foundation of China (81803414) | Jiangsu Province Natural Science Foundation (BK20170653) | Ministry of Sciences and Technologies (2016YFC1201000) | Nanjing University (2017BN04)

Authors: Xilin Wu | Xiaohua Ma | Yanlei Li | Yue Xu | Nan Zheng | Shijie Xu | Waqas Nawaz | Zhiwei Wu

FULLY AI-DRIVEN HUMANOID VHH PHAGE LIBRARY

JOURNAL ARTICLE published 24 July 2023 in Antibody Therapeutics

Authors: Yangyang Zhao | Le Niu | Xuemin Pan | Xingda Ye | Quan Yu | Yupeng Zhu | Yile Chen | Zhiwu Sun | Yunfei Long | Yi Li

YEAST SURFACE DISPLAY OF FULL-LENGTH IGG FOR ENGINEERING MONOCLONAL AND BISPECIFIC ANTIBODIES

JOURNAL ARTICLE published 24 July 2023 in Antibody Therapeutics

Authors: Youwei Jiang