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Synthesis, Potency, and In Vivo Profiles of Quinoline Containing Histamine H3Receptor Inverse Agonists JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry |
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Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes JOURNAL ARTICLE published 13 May 2021 in Journal of Medicinal Chemistry Research funded by California Institute for Regenerative Medicine (TR4-06857) |
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Design, Synthesis, and Multivariate Quantitative Structure−Activity Relationship of SalicylanilidesPotent Inhibitors of Type III Secretion inYersinia JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry |
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Bifunctional and Unusual Amino Acid β- or γ-Ester Prodrugs of Nucleoside Analogues for Improved Affinity to ATB0,+ and Enhanced Metabolic Stability: An Application to Floxuridine JOURNAL ARTICLE published 8 October 2020 in Journal of Medicinal Chemistry Research funded by National Natural Science Foundation of China (81360485,81560577,81860630) | Natural Science Foundation of Jiangxi Province (20181BAB205087) | Key Project of Jiangxi (20192ACB70012) |
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Syntheses and Biological Activities (Topoisomerase Inhibition and Antitumor and Antimicrobial Properties) of Rebeccamycin Analogues Bearing Modified Sugar Moieties and Substituted on the Imide Nitrogen with a Methyl Group JOURNAL ARTICLE published 1 October 1997 in Journal of Medicinal Chemistry |
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Synthesis and Antitumor Activities of Novel 6-5 Fused Ring Heterocycle Antifolates: N-[4-[.omega.-(2-Amino-4-substituted-6,7-dihydrocyclopenta[d]pyrimidin-5-yl)alkyl]benzoyl]-L-glutamic Acids JOURNAL ARTICLE published May 1994 in Journal of Medicinal Chemistry |
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Development of a Small Hybrid Molecule That Mediates Degradation of His-Tag Fused Proteins JOURNAL ARTICLE published 25 January 2018 in Journal of Medicinal Chemistry Research funded by Japan Society for the Promotion of Science (16H05090,16K15121,26460169) |
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Kinase-likeness and Kinase-Privileged Fragments: Toward Virtual Polypharmacology JOURNAL ARTICLE published 13 March 2008 in Journal of Medicinal Chemistry |
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Preventive Oral Treatment with Resveratrol Pro-prodrugs Drastically Reduce Colon Inflammation in Rodents JOURNAL ARTICLE published 28 October 2010 in Journal of Medicinal Chemistry |
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Development of Novel Aminoglycoside (NB54) with Reduced Toxicity and Enhanced Suppression of Disease-Causing Premature Stop Mutations JOURNAL ARTICLE published 14 May 2009 in Journal of Medicinal Chemistry |
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Synthesis and Anticancer Activity of Brefeldin A Ester Derivatives JOURNAL ARTICLE published 1 June 2006 in Journal of Medicinal Chemistry |
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Structure−Activity Relationships of New 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as Allosteric Enhancers of the A3 Adenosine Receptor JOURNAL ARTICLE published 1 June 2006 in Journal of Medicinal Chemistry |
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Synthesis and Antiprotozoal Activity of N-Alkoxy Analogues of the Trypanocidal Lead Compound 4,4′-Bis(imidazolinylamino)diphenylamine with Improved Human Blood−Brain Barrier Permeability JOURNAL ARTICLE published 27 January 2011 in Journal of Medicinal Chemistry |
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Enzyme-Activated Antagonists of the Strychnine-Insensitive Glycine/NMDA Receptor JOURNAL ARTICLE published February 1994 in Journal of Medicinal Chemistry |
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Synthesis and Characterization of an A6-A11 Methylene Thioacetal Human Insulin Analogue with Enhanced Stability JOURNAL ARTICLE published 26 December 2019 in Journal of Medicinal Chemistry Research funded by American Diabetes Association (#1-19-PDF110) | National Institute of Diabetes and Digestive and Kidney Diseases (R01DK120430) |
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Synthesis of (E)-5-(3,3,3-trifluoro-1-propenyl)-2'-deoxyuridine and related analogs: potent and unusually selective antiviral activity of (E)-5-(3,3,3-trifluoro-1-propenyl)-2'-deoxyridine against herpes simplex virus type 1 JOURNAL ARTICLE published March 1984 in Journal of Medicinal Chemistry |
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Novel Synthesis and Structural Characterization of a High-Affinity Paramagnetic Kinase Probe for the Identification of Non-ATP Site Binders by Nuclear Magnetic Resonance JOURNAL ARTICLE published 11 February 2010 in Journal of Medicinal Chemistry |
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Structure-Based Design, Synthesis, Evaluation, and Crystallographic Studies of Conformationally Constrained Smac Mimetics as Inhibitors of the X-linked Inhibitor of Apoptosis Protein (XIAP) JOURNAL ARTICLE published 27 November 2008 in Journal of Medicinal Chemistry |
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Effect of Chiral Purity on Adjuvanticity of Archaeol-Based Glycolipids JOURNAL ARTICLE published 23 June 2022 in Journal of Medicinal Chemistry |
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Synthesis and Anticonvulsant Activity of Amino Acid-Derived Sulfamides JOURNAL ARTICLE published 26 March 2009 in Journal of Medicinal Chemistry |