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Further Studies on Lead Compounds Containing the Opioid Pharmacophore Dmt-Tic

JOURNAL ARTICLE published 1 August 2008 in Journal of Medicinal Chemistry

Authors: Gianfranco Balboni | Stella Fiorini | Anna Baldisserotto | Claudio Trapella | Yusuke Sasaki | Akihiro Ambo | Ewa D. Marczak | Lawrence H. Lazarus | Severo Salvadori

Performance of Dark Chemical Matter in High Throughput Screening

JOURNAL ARTICLE published 10 November 2016 in Journal of Medicinal Chemistry

Authors: Ingo Muegge | Prasenjit Mukherjee

Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069”

JOURNAL ARTICLE published 12 January 2023 in Journal of Medicinal Chemistry

Authors: Douglas L. Orsi | Elisabeth Pook | Nico Bräuer | Anders Friberg | Philip Lienau | Christopher T. Lemke | Timo Stellfeld | Ulf Brüggemeier | Vera Pütter | Hanna Meyer | Maria Baco | Stephanie Tang | Andrew D. Cherniack | Lindsay Westlake | Samantha A. Bender | Mustafa Kocak | Craig A. Strathdee | Matthew Meyerson | Knut Eis | Jonathan T. Goldstein

De Novo Discovery of Serotonin N-Acetyltransferase Inhibitors

JOURNAL ARTICLE published 1 November 2007 in Journal of Medicinal Chemistry

Authors: Lawrence M. Szewczuk | S. Adrian Saldanha | Surajit Ganguly | Erin M. Bowers | Margarita Javoroncov | Balasubramanyam Karanam | Jeffrey C. Culhane | Marc A. Holbert | David C. Klein | Ruben Abagyan | Philip A. Cole

Heterocyclic Analogues of Modafinil as Novel, Atypical Dopamine Transporter Inhibitors

JOURNAL ARTICLE published 22 November 2017 in Journal of Medicinal Chemistry

Research funded by Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo (2016/10149-0)

Authors: Predrag Kalaba | Nilima Y. Aher | Marija Ilić | Vladimir Dragačević | Marcus Wieder | Andras G. Miklosi | Martin Zehl | Judith Wackerlig | Alexander Roller | Tetyana Beryozkina | Bojana Radoman | Sivaprakasam R. Saroja | Wolfgang Lindner | Eduardo Perez Gonzalez | Vasiliy Bakulev | Johann Jakob Leban | Harald H. Sitte | Ernst Urban | Thierry Langer | Gert Lubec

Combining Elements from Two Antagonists of Formyl Peptide Receptor 2 Generates More Potent Peptidomimetic Antagonists

JOURNAL ARTICLE published 24 August 2017 in Journal of Medicinal Chemistry

Authors: Sarah Line Skovbakke | André Holdfeldt | Christina Nielsen | Anna Mette Hansen | Iris Perez-Gassol | Claes Dahlgren | Huamei Forsman | Henrik Franzyk

Potent, Brain-Penetrant, Hydroisoindoline-Based Human Neurokinin-1 Receptor Antagonists

JOURNAL ARTICLE published 14 May 2009 in Journal of Medicinal Chemistry

Authors: Jinlong Jiang | Jaime L. Bunda | Geoge A. Doss | Gary G. Chicchi | Marc M. Kurtz | Kwei-Lan C. Tsao | Xinchun Tong | Song Zheng | Alana Upthagrove | Koppara Samuel | Richard Tschirret-Guth | Sanjeev Kumar | Alan Wheeldon | Emma J. Carlson | Richard Hargreaves | Donald Burns | Terence Hamill | Christine Ryan | Stephen M. Krause | WaiSi Eng | Robert J. DeVita | Sander G. Mills

Discovery and Characterization of BAY 1214784, an Orally Available Spiroindoline Derivative Acting as a Potent and Selective Antagonist of the Human Gonadotropin-Releasing Hormone Receptor as Proven in a First-In-Human Study in Postmenopausal Women

JOURNAL ARTICLE published 22 October 2020 in Journal of Medicinal Chemistry

Authors: Olaf Panknin | Andrea Wagenfeld | Wilhelm Bone | Eckhard Bender | Katrin Nowak-Reppel | Amaury E. Fernández-Montalván | Reinhard Nubbemeyer | Stefan Bäurle | Sven Ring | Norbert Schmees | Olaf Prien | Martina Schäfer | Christian Friedrich | Thomas M. Zollner | Andreas Steinmeyer | Thomas Mueller | Gernot Langer

Cytotoxicity and antitumor activity of bis(platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1,2-diaminocyclohexane complexes

JOURNAL ARTICLE published August 1990 in Journal of Medicinal Chemistry

Authors: Nicholas Farrell | Yun Qu | Miles P. Hacker

Design, Synthesis, and In Vitro Testing of α-Methylacyl-CoA Racemase Inhibitors

JOURNAL ARTICLE published 1 May 2007 in Journal of Medicinal Chemistry

Authors: Andrew J. Carnell | Ian Hale | Simone Denis | Ronald J. A. Wanders | William B. Isaacs | Brice A. Wilson | Sacha Ferdinandusse

New Substituted 1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)piperidin-4-yl Derivatives with α2-Adrenoceptor Antagonist Activity

JOURNAL ARTICLE published 1 October 2000 in Journal of Medicinal Chemistry

Authors: Patrice Mayer | Pascale Brunel | Céline Chaplain | Christel Piedecoq | Francis Calmel | Philippe Schambel | Philippe Chopin | Thierry Wurch | Petrus J. Pauwels | Marc Marien | Jean-Louis Vidaluc | Thierry Imbert

N-3-Substituted Imidazoquinazolinones:  Potent and Selective PDE5 Inhibitors as Potential Agents for Treatment of Erectile Dysfunction

JOURNAL ARTICLE published 6 April 2000 in Journal of Medicinal Chemistry

Authors: David P. Rotella | Zhong Sun | Yeheng Zhu | John Krupinski | Ronald Pongrac | Laurie Seliger | Diane Normandin | John E. Macor

DNA Binding Ligands Targeting Drug-Resistant Bacteria:  Structure, Activity, and Pharmacology

JOURNAL ARTICLE published 1 August 2003 in Journal of Medicinal Chemistry

Authors: Jacob A. Kaizerman | Matthew I. Gross | Yigong Ge | Sarah White | Wenhao Hu | Jian-Xin Duan | Eldon E. Baird | Kirk W. Johnson | Richard D. Tanaka | Heinz E. Moser | Roland W. Bürli

Isoxazolone Based Inhibitors of p38 MAP Kinases

JOURNAL ARTICLE published 1 April 2008 in Journal of Medicinal Chemistry

Authors: Stefan A. Laufer | Simona Margutti

Antineoplastic agents. Structure-activity relationship study of bis(substituted aminoalkylamino)anthraquinones

JOURNAL ARTICLE published March 1978 in Journal of Medicinal Chemistry

Authors: Robert K. Y. Zee-Cheng | C. C. Cheng

Potent and Selective Inhibitors of Human Sirtuin 5

JOURNAL ARTICLE published 22 March 2018 in Journal of Medicinal Chemistry

Research funded by Oberfrankenstiftung (04115)

Authors: Diana Kalbas | Sandra Liebscher | Theresa Nowak | Marat Meleshin | Martin Pannek | Corinna Popp | Zayan Alhalabi | Frank Bordusa | Wolfgang Sippl | Clemens Steegborn | Mike Schutkowski

Development of Orally Active Nonpeptidic Inhibitors of Human Neutrophil Elastase

JOURNAL ARTICLE published 1 April 2001 in Journal of Medicinal Chemistry

Authors: Kazuyuki Ohmoto | Tetsuya Yamamoto | Motohiro Okuma | Toshihide Horiuchi | Hirotoshi Imanishi | Yoshihiko Odagaki | Kazuhito Kawabata | Tomohiko Sekioka | Yasushi Hirota | Shozo Matsuoka | Hisao Nakai | Masaaki Toda | John C. Cheronis | Lyle W. Spruce | Albert Gyorkos | Maciej Wieczorek

Potent Lys Patch-Containing Stapled Peptides Targeting PCSK9

JOURNAL ARTICLE published 12 August 2021 in Journal of Medicinal Chemistry

Authors: Kévin Bourbiaux | Baptiste Legrand | Pascal Verdié | Sergio Mallart | Géraldine Manette | Claire Minoletti | J. David Stepp | Philippe Prigent | Jean-Christophe Le Bail | Laurence Gauzy-Lazo | Olivier Duclos | Jean Martinez | Muriel Amblard

Drugs and the Pharmaceutical Sciences. Volume 100. New Drug Approval Process, 3rd Edition Edited by Richard A. Guarino. Marcel Dekker, Inc., New York. 1999. xxxiii + 471 pp. 16 × 23.5 cm. ISBN 0-8247-0308-1. $185.00.

JOURNAL ARTICLE published 1 February 2000 in Journal of Medicinal Chemistry

Authors: Bruce Ronsen

Organic Synthesis Highlights II Edited by Herbert Waldmann. VCH, Weinheim and New York. 1995. ix + 407 pp. 17.5 × 24.5 cm. ISBN 3-527-29200-4. $98.00.

JOURNAL ARTICLE published 1 January 1996 in Journal of Medicinal Chemistry

Authors: Richard E. Mewshaw