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Showing results for ISSN matching 0022-2623

Synthesis and in Vitro Activity of Some Aryl Diaziridines as Potential Monoamine Oxidase Inhibitors1a-c

JOURNAL ARTICLE published September 1964 in Journal of Medicinal Chemistry

Authors: Charles J. Paget | Charles S. Davis

https://doi.org/10.1021/jm00335a012 Actions

Identification of 5-Substituted 2-Acylaminothiazoles That Activate Tat-Mediated Transcription in HIV-1 Latency Models

JOURNAL ARTICLE published 23 May 2019 in Journal of Medicinal Chemistry

Research funded by National Health and Medical Research Council (1113712,1129320,1052979)

Authors: William Nguyen | Jonathan Jacobson | Kate E. Jarman | Helene Jousset Sabroux | Leigh Harty | James McMahon | Sharon R. Lewin | Damian F. Purcell | Brad E. Sleebs

https://doi.org/10.1021/acs.jmedchem.9b00462 Actions

1-((S)-2-Aminopropyl)-1H-indazol-6-ol:  A Potent Peripherally Acting 5-HT2Receptor Agonist with Ocular Hypotensive Activity

JOURNAL ARTICLE published 1 January 2006 in Journal of Medicinal Chemistry

Authors: Jesse A. May | Anura P. Dantanarayana | Paul W. Zinke | Marsha A. McLaughlin | Najam A. Sharif

https://doi.org/10.1021/jm050663x Actions

Quinuclidine chemistry. 4. Diuretic properties of cis-3-amino-2-benzhydrylquinuclidine

JOURNAL ARTICLE published June 1975 in Journal of Medicinal Chemistry

Authors: E. J. Warawa | N. J. Mueller | J. Stuart Fleming

https://doi.org/10.1021/jm00240a013 Actions

Probing the Activity Differences of Simple and Complex Brominated Aryl Compounds against 15-Soybean, 15-Human, and 12-Human Lipoxygenase

JOURNAL ARTICLE published 1 July 2004 in Journal of Medicinal Chemistry

Authors: Erika N. Segraves | Rachana R. Shah | Nathaniel L. Segraves | Tyler A. Johnson | Stephanie Whitman | Jennifer K. Sui | Victor A. Kenyon | Robert H. Cichewicz | Phillip Crews | Theodore R. Holman

https://doi.org/10.1021/jm049872s Actions

Synthesis and Structure−Activity Relationship of 2-Aminobenzophenone Derivatives as Antimitotic Agents

JOURNAL ARTICLE published 1 June 2002 in Journal of Medicinal Chemistry

Authors: Jing-Ping Liou | Chun-Wei Chang | Jeng-Shin Song | Yung-Ning Yang | Ching-Fang Yeh | Huan-Yi Tseng | Yu-Kang Lo | Yi-Ling Chang | Chung-Ming Chang | Hsing-Pang Hsieh

https://doi.org/10.1021/jm010365+ Actions

Design and Synthesis of 8-Octyl-benzolactam-V9, a Selective Activator for Protein Kinase Cε and η

JOURNAL ARTICLE published 1 May 2006 in Journal of Medicinal Chemistry

Authors: Yu Nakagawa | Kazuhiro Irie | Ryo C. Yanagita | Hajime Ohigashi | Ken-ichiro Tsuda | Kaori Kashiwagi | Naoaki Saito

https://doi.org/10.1021/jm050857c Actions

1-Benzhydryl-3-phenylurea and 1-Benzhydryl-3-phenylthiourea Derivatives:  New Templates among the CB1 Cannabinoid Receptor Inverse Agonists

JOURNAL ARTICLE published 1 November 2005 in Journal of Medicinal Chemistry

Authors: Giulio G. Muccioli | Johan Wouters | Gerhard K. E. Scriba | Wolfgang Poppitz | Jacques H. Poupaert | Didier M. Lambert

https://doi.org/10.1021/jm0503906 Actions

Studies on biologically active halogenated compounds. 1. Synthesis and central nervous system depressant activity of 2-(fluoromethyl)-3-aryl-4(3H)-quinazolinone derivatives

JOURNAL ARTICLE published January 1979 in Journal of Medicinal Chemistry

Authors: Junichi Tani | Yoshihisa Yamada | Toyonari Oine | Takashi Ochiai | Ryuichi Ishida | Ichizo Inoue

https://doi.org/10.1021/jm00187a021 Actions

Substituted Pyrazolopyridines as Potent and Selective PDE5 Inhibitors:  Potential Agents for Treatment of Erectile Dysfunction

JOURNAL ARTICLE published 1 March 2001 in Journal of Medicinal Chemistry

Authors: Guixue Yu | Helen J. Mason | Ximao Wu | Jian Wang | Saeho Chong | Gary Dorough | Andrew Henwood | Ronald Pongrac | Laurie Seliger | Bin He | Diane Normandin | Leonard Adam | John Krupinski | John E. Macor

https://doi.org/10.1021/jm0155042 Actions

Antianaphylactic agents. 4. Synthesis and structure-activity relations of 3-(4-oxo-4H-1-benzopyran-3)acrylic acids, a new series of antiallergic substances, and some related compounds

JOURNAL ARTICLE published January 1975 in Journal of Medicinal Chemistry

Authors: Akira Nohara | Hisashi Kuriki | Taketoshi Saijo | Kiyoshi Ukawa | Tadakazu Murata | Morio Kanno | Yasushi Sanno

https://doi.org/10.1021/jm00235a008 Actions

Development of o-Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora Kinase Inhibitors

JOURNAL ARTICLE published 13 September 2012 in Journal of Medicinal Chemistry

Authors: Harshani R. Lawrence | Mathew P. Martin | Yunting Luo | Roberta Pireddu | Hua Yang | Harsukh Gevariya | Sevil Ozcan | Jin-Yi Zhu | Robert Kendig | Mercedes Rodriguez | Roy Elias | Jin Q. Cheng | Saïd M. Sebti | Ernst Schonbrunn | Nicholas J. Lawrence

https://doi.org/10.1021/jm300334d Actions

Antitumor agents. II. Bis(guanylhydrazones) of anthracene-9,10-dicarboxaldehydes

JOURNAL ARTICLE published May 1982 in Journal of Medicinal Chemistry

Authors: K. C. Murdock | R. G. Child | Yang I Lin | J. D. Warren | P. F. Fabio | Ving J. Lee | P. T. Izzo | S. A. Lang | Robert B. Angier

https://doi.org/10.1021/jm00347a006 Actions

Synthesis and anthelmintic activity of 5(6)-[(benzimidazol-2-yl)carboxamido]- and (4-substituted piperazin-1-yl)benzimidazoles

JOURNAL ARTICLE published November 1985 in Journal of Medicinal Chemistry

Authors: Rashmi Dubey | Syed Abuzar | Satyavan Sharma | R. K. Chatterjee | J. C. Katiyar

https://doi.org/10.1021/jm00149a036 Actions

In Vitro and In Vivo Demonstration of Human-Ovarian-Cancer Necrosis through a Water-Soluble and Near-Infrared-Absorbing Chlorin

JOURNAL ARTICLE published 14 June 2018 in Journal of Medicinal Chemistry

Research funded by Department of Biotechnology , Ministry of Science and Technology (BMB/2015/53) | Department of Science and Technology, Ministry of Science and Technology (SR/S5/MBD-01C/2007)

Authors: Betsy Marydasan | Bollapalli Madhuri | Shirisha Cherukommu | Jedy Jose | Mambattakkara Viji | Suneesh C. Karunakaran | Tavarekere K. Chandrashekar | Kunchala Sridhar Rao | Ch. Mohan Rao | Danaboyina Ramaiah

https://doi.org/10.1021/acs.jmedchem.8b00460 Actions

Syntheses and anthelmintic activity of alkyl 5(6)-(substituted carbamoyl)- and 5(6)-(disubstituted carbamoyl)benzimidazole-2-carbamates and related compounds

JOURNAL ARTICLE published August 1984 in Journal of Medicinal Chemistry

Authors: Shiv Kumar | Manju Seth | Amiya P. Bhaduri | Pradeep K. S. Visen | Anuradha Misra | Suman Gupta | Nigar Fatima | Jagdish C. Katiyar | Ranjeet K. Chatterjee | Amiya B. Sen

https://doi.org/10.1021/jm00374a025 Actions

Synthesis and Biological Evaluation of 2-Amino-3-(3‘,4‘,5‘-trimethoxybenzoyl)-5-aryl Thiophenes as a New Class of Potent Antitubulin Agents

JOURNAL ARTICLE published 1 June 2006 in Journal of Medicinal Chemistry

Authors: Romeo Romagnoli | Pier Giovanni Baraldi | Maria Giovanna Pavani | Mojgan Aghazadeh Tabrizi | Delia Preti | Francesca Fruttarolo | Laura Piccagli | M. Katherine Jung | Ernest Hamel | Monica Borgatti | Roberto Gambari

https://doi.org/10.1021/jm060355e Actions

Synthesis and biological effects of acyclic pyrimidine nucleoside analogs

JOURNAL ARTICLE published September 1981 in Journal of Medicinal Chemistry

Authors: Alan C. Schroeder | Robert G. Hughes | Alexander Bloch

https://doi.org/10.1021/jm00141a012 Actions

Identification of New Diamine Scaffolds with Activity against Mycobacterium tuberculosis

JOURNAL ARTICLE published 1 June 2006 in Journal of Medicinal Chemistry

Authors: Elena Bogatcheva | Colleen Hanrahan | Boris Nikonenko | Rowena Samala | Ping Chen | Jacqueline Gearhart | Francis Barbosa | Leo Einck | Carol A. Nacy | Marina Protopopova

https://doi.org/10.1021/jm050948+ Actions

A Nonpeptidic Sulfonamide Inhibits the p53−mdm2 Interaction and Activates p53-Dependent Transcription in mdm2-Overexpressing Cells

JOURNAL ARTICLE published 1 August 2004 in Journal of Medicinal Chemistry

Authors: Peter S. Galatin | Donald J. Abraham

https://doi.org/10.1021/jm034182u Actions
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