Tumor Microenvironment in Gene Signatures: Critical Biology or Confounding Noise?

JOURNAL ARTICLE published 15 August 2016 in Clinical Cancer Research

Research funded by NCI (CA178744) | National Science Foundation (1550088) | NCI NIH (CA172670 and CA184843)

Authors: Jeffrey S. Morris | Scott Kopetz

Neoantigen Identification and Response to Adoptive Cell Transfer in Anti–PD-1 Naïve and Experienced Patients with Metastatic Melanoma

JOURNAL ARTICLE published 15 July 2022 in Clinical Cancer Research

Authors: Shoshana T. Levi | Amy R. Copeland | Shirley Nah | Jessica S. Crystal | Gabriel D. Ivey | Almin Lalani | Mohammad Jafferji | Bradley S. White | Neilesh B. Parikh | Vid Leko | Sri Krishna | Frank Lowery | Todd D. Prickett | Jared J. Gartner | Li Jia | Yong F. Li | Abraham Sachs | Sivasish Sindiri | Welles Robinson | Billel Gasmi | James C. Yang | Stephanie L. Goff | Steven A. Rosenberg | Paul F. Robbins

Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers

JOURNAL ARTICLE published 15 July 2017 in Clinical Cancer Research

Research funded by National Center for Advancing Translational Sciences (UL1 TR000371) | National Institutes of Health MD Anderson Cancer Center (P30 CA016672) | University of Southern California's Cancer Center (P30 CA014089) | Seventh Framework Programme (602901MErCuRIC,635342-2 MoTriColor,115749 CANCER-ID) | AIRC (9970,IGn. 16788)

Authors: Takeo Fujii | Afsaneh Barzi | Andrea Sartore-Bianchi | Andrea Cassingena | Giulia Siravegna | Daniel D. Karp | Sarina A. Piha-Paul | Vivek Subbiah | Apostolia M. Tsimberidou | Helen J. Huang | Silvio Veronese | Federica Di Nicolantonio | Sandeep Pingle | Cecile Rose T. Vibat | Saege Hancock | David Berz | Vladislava O. Melnikova | Mark G. Erlander | Rajyalakshmi Luthra | E. Scott Kopetz | Funda Meric-Bernstam | Salvatore Siena | Heinz-Josef Lenz | Alberto Bardelli | Filip Janku

Molecular Pathways: Targeting Hsp90—Who Benefits and Who Does Not

JOURNAL ARTICLE published 1 September 2012 in Clinical Cancer Research

Authors: Maurizio Scaltriti | Shaheenah Dawood | Javier Cortes

A Histone Deacetylase Inhibitor, Panobinostat, Enhances Chimeric Antigen Receptor T-cell Antitumor Effect Against Pancreatic Cancer

JOURNAL ARTICLE published 15 November 2021 in Clinical Cancer Research

Research funded by NHMRC (1103352,1132373,1136680,1176935) | NBCF (IIRS-18-064,IIRS-20-073) | Susan G. Komen Breast Cancer Foundation (16376637)

Authors: Aesha I. Ali | Minyu Wang | Bianca von Scheidt | Pilar M. Dominguez | Aaron J. Harrison | Daniela G.M. Tantalo | Jian Kang | Amanda J. Oliver | Jack D. Chan | Xin Du | Yuchen Bai | Belinda Lee | Ricky W. Johnstone | Phillip K. Darcy | Michael H. Kershaw | Clare Y. Slaney

Notch1 Expression Predicts an Unfavorable Prognosis and Serves as a Therapeutic Target of Patients with Neuroblastoma

JOURNAL ARTICLE published 1 September 2010 in Clinical Cancer Research

Authors: Hsiu-Hao Chang | Hsinyu Lee | Ming-Kuan Hu | Po-Nien Tsao | Hsueh-Fen Juan | Min-Chuan Huang | Yu-Yin Shih | Bo-Jeng Wang | Yung-Ming Jeng | Christina Ling Chang | Shiu-Feng Huang | Yeou-Guang Tsay | Fon-Jou Hsieh | Kai-Hsin Lin | Wen-Ming Hsu | Yung-Feng Liao

Research Priorities, Measures, and Recommendations for Assessment of Tobacco Use in Clinical Cancer Research

JOURNAL ARTICLE published 15 April 2016 in Clinical Cancer Research

Authors: Stephanie R. Land | Benjamin A. Toll | Carol M. Moinpour | Sandra A. Mitchell | Jamie S. Ostroff | Dorothy K. Hatsukami | Sonia A. Duffy | Ellen R. Gritz | Nancy A. Rigotti | Thomas H. Brandon | Sheila A. Prindiville | Linda P. Sarna | Robert A. Schnoll | Roy S. Herbst | Paul M. Cinciripini | Scott J. Leischow | Carolyn M. Dresler | Michael C. Fiore | Graham W. Warren

Association of AR-V7 and Prostate-Specific Antigen RNA Levels in Blood with Efficacy of Abiraterone Acetate and Enzalutamide Treatment in Men with Prostate Cancer

JOURNAL ARTICLE published 1 February 2017 in Clinical Cancer Research

Research funded by Dana-Farber Cancer Institute (P50CA090381)

Authors: Fangfang Qu | Wanling Xie | Mari Nakabayashi | Haitao Zhang | Seong Ho Jeong | Xiaodong Wang | Kazumasa Komura | Christopher J. Sweeney | Oliver Sartor | Gwo-Shu Mary Lee | Philip W. Kantoff

A First-in-Human Study of Conatumumab in Adult Patients with Advanced Solid Tumors

JOURNAL ARTICLE published 1 December 2010 in Clinical Cancer Research

Authors: Roy S. Herbst | Razelle Kurzrock | David S. Hong | Manuel Valdivieso | Cheng-Pang Hsu | Lovely Goyal | Gloria Juan | Yuying C. Hwang | Susan Wong | John S. Hill | Greg Friberg | Patricia M. LoRusso

Aging and CNS Myeloid Cell Depletion Attenuate Breast Cancer Brain Metastasis

JOURNAL ARTICLE published 1 August 2021 in Clinical Cancer Research

Research funded by U.S. Department of Defense Breast Cancer Research Program (W81 XWH-062-003.3) | NIH (HHSN261200800001E) | NIH (R24HD102061)

Authors: Alex Man Lai Wu | Selamawit Gossa | Ramakrishna Samala | Monika A. Chung | Brunilde Gril | Howard H. Yang | Helen R. Thorsheim | Andy D. Tran | Debbie Wei | Esra Taner | Kristine Isanogle | Yuan Yang | Emma L. Dolan | Christina Robinson | Simone Difilippantonio | Maxwell P. Lee | Imran Khan | Quentin R. Smith | Dorian B. McGavern | Lalage M. Wakefield | Patricia S. Steeg

Preclinical Characterization and Phase I Trial Results of INBRX-109, A Third-Generation, Recombinant, Humanized, Death Receptor 5 Agonist Antibody, in Chondrosarcoma

JOURNAL ARTICLE published 15 August 2023 in Clinical Cancer Research

Authors: Vivek Subbiah | Sant P. Chawla | Anthony P. Conley | Breelyn A. Wilky | Anthony Tolcher | Nehal J. Lakhani | David Berz | Vasily Andrianov | William Crago | Monica Holcomb | Abrahim Hussain | Carson Veldstra | James Kalabus | Brianne O’Neill | Lane Senne | Emily Rowell | Analeah B. Heidt | Katelyn M. Willis | Brendan P. Eckelman

Spontaneous Regression of High-Grade Cervical Dysplasia: Effects of Human Papillomavirus Type and HLA Phenotype

JOURNAL ARTICLE published 1 July 2005 in Clinical Cancer Research

Authors: Cornelia L. Trimble | Steven Piantadosi | Patti Gravitt | Brigitte Ronnett | Ellen Pizer | Andrea Elko | Barbara Wilgus | William Yutzy | Richard Daniel | Keerti Shah | Shiwen Peng | Chienfu Hung | Richard Roden | Tzyy Choou Wu | Drew Pardoll | The Johns Hopkins Medical Institutions, Baltimore, MD

Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages

JOURNAL ARTICLE published 1 February 2017 in Clinical Cancer Research

Authors: Don-Hong Wang | Hyun-Sung Lee | David Yoon | Gerald Berry | Thomas M. Wheeler | David J. Sugarbaker | Farrah Kheradmand | Edgar Engleman | Bryan M. Burt

Stress, Immunity, and Cervical Cancer: Biobehavioral Outcomes of a Randomized Clinical Trail

JOURNAL ARTICLE published 1 April 2008 in Clinical Cancer Research

Authors: Edward L. Nelson | Lari B. Wenzel | Kathryn Osann | Aysun Dogan-Ates | Nissa Chantana | Astrid Reina-Patton | Amanda K. Laust | Kevin P. Nishimoto | Alexandra Chicz-DeMet | Nefertiti du Pont | Bradley J. Monk

Differential Sensitivity Analysis for Resistant Malignancies (DISARM) Identifies Common Candidate Therapies across Platinum-Resistant Cancers

JOURNAL ARTICLE published 1 January 2019 in Clinical Cancer Research

Research funded by NIH NCI (T32 CA-009666) | NIH NCI (1-R01-CA207295)

Authors: Carl M. Gay | Pan Tong | Robert J. Cardnell | Triparna Sen | Xiao Su | Jun Ma | Rasha O. Bara | Faye M. Johnson | Chris Wakefield | John V. Heymach | Jing Wang | Lauren A. Byers

Refining Immunotherapy Approvals

JOURNAL ARTICLE published 1 September 2017 in Clinical Cancer Research

Authors: Susan E. Bates

Disruption of in vivo Chronic Lymphocytic Leukemia Tumor–Microenvironment Interactions by Ibrutinib – Findings from an Investigator-Initiated Phase II Study

JOURNAL ARTICLE published 1 April 2016 in Clinical Cancer Research

Authors: Carsten U. Niemann | Sarah E.M. Herman | Irina Maric | Julio Gomez-Rodriguez | Angelique Biancotto | Betty Y. Chang | Sabrina Martyr | Maryalice Stetler-Stevenson | Constance M. Yuan | Katherine R. Calvo | Raul C. Braylan | Janet Valdez | Yuh Shan Lee | Deanna H. Wong | Jade Jones | Clare Sun | Gerald E. Marti | Mohammed Z.H. Farooqui | Adrian Wiestner

Multicenter Phase I/II Trial of Napabucasin and Pembrolizumab in Patients with Metastatic Colorectal Cancer (EPOC1503/SCOOP Trial)

JOURNAL ARTICLE published 15 November 2020 in Clinical Cancer Research

Research funded by Dainippon Sumitomo Pharma (NA)

Authors: Akihito Kawazoe | Yasutoshi Kuboki | Eiji Shinozaki | Hiroki Hara | Tomohiro Nishina | Yoshito Komatsu | Satoshi Yuki | Masashi Wakabayashi | Shogo Nomura | Akihiro Sato | Takeshi Kuwata | Masahito Kawazu | Hiroyuki Mano | Yosuke Togashi | Hiroyoshi Nishikawa | Takayuki Yoshino

A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of BRAF-mutated Melanoma to MAPK Inhibitors

JOURNAL ARTICLE published 15 November 2019 in Clinical Cancer Research

Research funded by Swiss National Science Foundation (31003A_166245) | NIH (P01 CA114046,P50 CA174523,U54 CA224070)

Authors: Andrea Aloia | Daniela Müllhaupt | Christophe D. Chabbert | Tanja Eberhart | Stefanie Flückiger-Mangual | Ana Vukolic | Ossia Eichhoff | Anja Irmisch | Leila T. Alexander | Ernesto Scibona | Dennie T. Frederick | Benchun Miao | Tian Tian | Chaoran Cheng | Lawrence N. Kwong | Zhi Wei | Ryan J. Sullivan | Genevieve M. Boland | Meenhard Herlyn | Keith T. Flaherty | Nicola Zamboni | Reinhard Dummer | Gao Zhang | Mitchell P. Levesque | Wilhelm Krek | Werner J. Kovacs

Camrelizumab Plus Gemcitabine, Vinorelbine, and Pegylated Liposomal Doxorubicin in Relapsed/Refractory Primary Mediastinal B-Cell Lymphoma: A Single-Arm, Open-Label, Phase II Trial

JOURNAL ARTICLE published 1 September 2020 in Clinical Cancer Research

Research funded by Science & Technology from Beijing (Z181100006318004) | National Natural Science Foundation of China (81773248) | National Natural Science Foundation of China (31991171,81830002) | National Key Research and Development Program of China (2016YFC1303501,2016YFC1303504) | National Excellent Young Scholar Science Fund (2017-YQPY-003)

Authors: Qian Mei | Wenying Zhang | Yang Liu | Qingming Yang | John E.J. Rasko | Jing Nie | Jiejie Liu | Xiang Li | Liang Dong | Meixia Chen | Yan Zhang | Lu Shi | Huitao Wu | Weidong Han