APOBEC and Cancer Viroimmunotherapy: Thinking the Unthinkable

JOURNAL ARTICLE published 15 June 2021 in Clinical Cancer Research

Research funded by NIH (P50 CA210964,R01CA108961)

Authors: Richard G. Vile | Alan Melcher | Hardev Pandha | Kevin J. Harrington | Jose S. Pulido

Triptolide Inhibits Bcr-Abl Transcription and Induces Apoptosis in STI571-resistant Chronic Myelogenous Leukemia Cells Harboring T315I Mutation

JOURNAL ARTICLE published 1 March 2009 in Clinical Cancer Research

Authors: Xianping Shi | Yanli Jin | Chao Cheng | Hui Zhang | Waiyi Zou | Qin Zheng | Zhongzheng Lu | Qi Chen | Yingrong Lai | Jingxuan Pan

Inflammation Mediates the Development of Aggressive Breast Cancer Following Radiotherapy

JOURNAL ARTICLE published 15 March 2021 in Clinical Cancer Research

Research funded by NASA (NNX09AM52G,NNX13AF06G) | NIH (R01CA190980)

Authors: Lin Ma | Alba Gonzalez-Junca | Yufei Zheng | Haoxu Ouyang | Irineu Illa-Bochaca | Kathleen C. Horst | Gregor Krings | Yinghao Wang | Ignacio Fernandez-Garcia | William Chou | Mary Helen Barcellos-Hoff

Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression

JOURNAL ARTICLE published 15 July 2016 in Clinical Cancer Research

Authors: Xiao-Min Yu | Renata Jaskula-Sztul | Maria R. Georgen | Zviadi Aburjania | Yash R. Somnay | Glen Leverson | Rebecca S. Sippel | Ricardo V. Lloyd | Brian P. Johnson | Herbert Chen

Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer

JOURNAL ARTICLE published 15 September 2022 in Clinical Cancer Research

Research funded by Deutsche Forschungsgemeinschaft (DGF SI 1347/3-1)

Authors: Christian F. Singer | Frederik Holst | Stefan Steurer | Eike C. Burandt | Sigurd F. Lax | Raimund Jakesz | Margaretha Rudas | Herbert Stöger | Richard Greil | Guido Sauter | Martin Filipits | Ronald Simon | Michael Gnant | for the ABCSG | for the ABCSG | for the ABCSG | for the ABCSG

Compartmental Analysis of T-cell Clonal Dynamics as a Function of Pathologic Response to Neoadjuvant PD-1 Blockade in Resectable Non–Small Cell Lung Cancer

JOURNAL ARTICLE published 15 March 2020 in Clinical Cancer Research

Research funded by NIH (R01 HG009518) | NIH (R01 CA203891-01A1) | SU2C AACR (SU2C-AACR-DT1012) | NIH (CA121113) | NIH (CA121113,CA180950) | NCI (R01CA142779) | NIH (T32 CA193145) | NIH (P30 CA008747) | NIH (P30 CA008748) | NIH NCI (R01 CA056821)

Authors: Jiajia Zhang | Zhicheng Ji | Justina X. Caushi | Margueritta El Asmar | Valsamo Anagnostou | Tricia R. Cottrell | Hok Yee Chan | Prerna Suri | Haidan Guo | Taha Merghoub | Jamie E. Chaft | Joshua E. Reuss | Ada J. Tam | Richard L. Blosser | Mohsen Abu-Akeel | John-William Sidhom | Ni Zhao | Jinny S. Ha | David R. Jones | Kristen A. Marrone | Jarushka Naidoo | Edward Gabrielson | Janis M. Taube | Victor E. Velculescu | Julie R. Brahmer | Franck Housseau | Matthew D. Hellmann | Patrick M. Forde | Drew M. Pardoll | Hongkai Ji | Kellie N. Smith

DNA Damage and Repair in Translational Oncology: An Overview

JOURNAL ARTICLE published 15 September 2010 in Clinical Cancer Research

Authors: Eddie Reed

Improved Assessment of Response Status in Patients with Pancreatic Cancer Treated with Neoadjuvant Therapy using Somatic Mutations and Liquid Biopsy Analysis

JOURNAL ARTICLE published 1 February 2021 in Clinical Cancer Research

Research funded by the Nikki Mitchell Foundation (NA) | the Ben and Rose Cole Charitable Pria Foundation (NA)

Authors: Lingdi Yin | Ning Pu | Elizabeth Thompson | Yi Miao | Christopher Wolfgang | Jun Yu

Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component

JOURNAL ARTICLE published 15 August 2017 in Clinical Cancer Research

Authors: Bracha Erlanger Avigdor | Katie Beierl | Christopher D. Gocke | Daniel J. Zabransky | Karen Cravero | Kelly Kyker-Snowman | Berry Button | David Chu | Sarah Croessmann | Rory L. Cochran | Roisin M. Connolly | Ben H. Park | Sarah J. Wheelan | Ashley Cimino-Mathews

Randomized Phase II Study of Axitinib versus Observation in Patients with Recurred or Metastatic Adenoid Cystic Carcinoma

JOURNAL ARTICLE published 1 October 2021 in Clinical Cancer Research

Research funded by Ministry of Health and Welfare (1720150)

Authors: Eun Joo Kang | Myung-Ju Ahn | Chan-Young Ock | Keun-Wook Lee | Jung Hye Kwon | Yaewon Yang | Yoon Hee Choi | Min Kyoung Kim | Jun Ho Ji | Tak Yun | Byung-Ho Nam | Sung-Bae Kim | Bhumsuk Keam

Disruption of Wnt/β-Catenin Exerts Antileukemia Activity and Synergizes with FLT3 Inhibition in FLT3-Mutant Acute Myeloid Leukemia

JOURNAL ARTICLE published 15 May 2018 in Clinical Cancer Research

Research funded by PRISM (C-82,PRI-724) | NIH (CA055164) | MD Anderson Cancer Center (CA016672) | Cancer Prevention Research Institute of Texas (RP121010)

Authors: Xuejie Jiang | Po Yee Mak | Hong Mu | Wenjing Tao | Duncan H. Mak | Steven Kornblau | Qi Zhang | Peter Ruvolo | Jared K. Burks | Weiguo Zhang | Teresa McQueen | Rongqing Pan | Hongsheng Zhou | Marina Konopleva | Jorge Cortes | Qifa Liu | Michael Andreeff | Bing Z. Carter

Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects

JOURNAL ARTICLE published 15 November 2014 in Clinical Cancer Research

Authors: Tracy T. Batchelor | David A. Reardon | John F. de Groot | Wolfgang Wick | Michael Weller

Microsatellite Instability Testing in Colorectal Carcinoma: Choice of Markers Affects Sensitivity of Detection of Mismatch Repair–Deficient Tumors

JOURNAL ARTICLE published 15 March 2005 in Clinical Cancer Research

Authors: Stephanie B. Hatch | Harry M. Lightfoot | Christopher P. Garwacki | Dominic T. Moore | Benjamin F. Calvo | John T. Woosley | Janiece Sciarrotta | William K. Funkhouser | Rosann A. Farber

Molecular Pathways: Translational and Therapeutic Implications of the Notch Signaling Pathway in Cancer

JOURNAL ARTICLE published 1 March 2015 in Clinical Cancer Research

Authors: Rebecca A. Previs | Robert L. Coleman | Adrian L. Harris | Anil K. Sood

Therapeutic Inhibition of the MDM2–p53 Interaction Prevents Recurrence of Adenoid Cystic Carcinomas

JOURNAL ARTICLE published 15 February 2017 in Clinical Cancer Research

Authors: Felipe Nör | Kristy A. Warner | Zhaocheng Zhang | Gerson A. Acasigua | Alexander T. Pearson | Samuel A. Kerk | Joseph I. Helman | Manoel Sant'Ana Filho | Shaomeng Wang | Jacques E. Nör

Improvements in Clinical Outcomes for BRAFV600E-Mutant Metastatic Colorectal Cancer

JOURNAL ARTICLE published 1 September 2020 in Clinical Cancer Research

Authors: Van K. Morris | Tanios Bekaii-Saab

Prognostic Value of Residual Disease after Neoadjuvant Therapy in HER2-Positive Breast Cancer Evaluated by Residual Cancer Burden, Neoadjuvant Response Index, and Neo-Bioscore

JOURNAL ARTICLE published 15 August 2019 in Clinical Cancer Research

Authors: Tessa G. Steenbruggen | Maartje van Seijen | Liselore M. Janssen | Mette S. van Ramshorst | Erik van Werkhoven | Marie-Jeanne T.D.F. Vrancken Peeters | Jelle Wesseling | Esther H. Lips | Gabe S. Sonke

Structural and Functional Alterations of FLT3 in Acute Myeloid Leukemia

JOURNAL ARTICLE published 1 July 2009 in Clinical Cancer Research

Authors: Soheil Meshinchi | Frederick R. Appelbaum

Clinical Impact of Presurgery Circulating Tumor DNA after Total Neoadjuvant Treatment in Locally Advanced Rectal Cancer: A Biomarker Study from the GEMCAD 1402 Trial

JOURNAL ARTICLE published 15 May 2021 in Clinical Cancer Research

Research funded by Instituto de Salud Carlos III – FEDER (PI18/00031) | ISCIII (JR18/00003)

Authors: Joana Vidal | David Casadevall | Beatriz Bellosillo | Carles Pericay | Rocio Garcia-Carbonero | Ferran Losa | Laia Layos | Vicente Alonso | Jaume Capdevila | Javier Gallego | Ruth Vera | Antonieta Salud | Marta Martin-Richard | Miguel Nogué | Elena Cillán | Joan Maurel | Iris Faull | Victoria Raymond | Carlos Fernández-Martos | Clara Montagut

Highlights of This Issue

JOURNAL ARTICLE published 1 January 2018 in Clinical Cancer Research