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Straightforward Access to 2-Iodoindolizines via Iodine-Mediated Cyclization of 2-Pyridylallenes

JOURNAL ARTICLE published 15 May 2020 in Organic Process Research & Development

Authors: Thibaut Martinez | Ismail Alahyen | Gilles Lemière | Virginie Mouriès-Mansuy | Louis Fensterbank

A New Efficient Synthetic Process for an Endothelin Receptor Antagonist, Bosentan Monohydrate

JOURNAL ARTICLE published 16 August 2013 in Organic Process Research & Development

Authors: Pradeep Rebelli | Jayaprakash Rao Yerrabelly | Bharathi Kumari Yalamanchili | Rajashekar Kommera | Venkat Reddy Ghojala | Kondal Reddy Bairy

Development of a Scalable Synthesis of Mevidalen (LY3154207), an Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor

JOURNAL ARTICLE published 20 November 2020 in Organic Process Research & Development

Authors: Jeffery Richardson | Kevin P. Cole | Amy C. DeBaillie | Junliang Hao | Jared Piper | Peter Houghton | John Rizzo | Mo Jia | Peng Liu | Ping Huang | Katarina Kadlecikova | Conchita F. Garcia | Daniel S. Richards

An Optimized Scalable Fully Automated Solid-Phase Microwave-Assisted cGMP-Ready Process for the Preparation of Eptifibatide

JOURNAL ARTICLE published 19 March 2021 in Organic Process Research & Development

Authors: Giuseppina Sabatino | Annunziata D’Ercole | Lorenzo Pacini | Matteo Zini | Arianna Ribecai | Alfredo Paio | Paolo Rovero | Anna Maria Papini

Highly Efficient Multigram Synthesis of Dibenzoazacyclooctyne (DBCO) without Chromatography

JOURNAL ARTICLE published 20 December 2019 in Organic Process Research & Development

Authors: Stuart A. McNelles | Julia L. Pantaleo | Alex Adronov

Stereoselective Nickel(II)-Catalyzed Addition of Aryl Grignards to Diphenylacetylene in the Synthesis of Zuclomiphene

JOURNAL ARTICLE published 15 April 2022 in Organic Process Research & Development

Authors: Avedis Karadeolian | Michael Emmett | Fabio Souza | Andrew Chung | Peter Blazecka | Richard Le Sueur | Dineshkumar Patel | Yajun Zhao | Allan Rey | Stuart Green

Biobased Chemicals: 1,2,4-Benzenetriol, Selective Deuteration and Dimerization to Bifunctional Aromatic Compounds

JOURNAL ARTICLE published 21 December 2018 in Organic Process Research & Development

Research funded by Stichting voor Fundamenteel Onderzoek der Materie (BBE1712) | Syncom (BBE1712)

Authors: Caelan Randolph | Ciaran W. Lahive | Selim Sami | Remco W. A. Havenith | Hero J. Heeres | Peter J. Deuss

Correction to “Development of a Kilogram-Scale Synthesis of a Novel Anti-HCV Agent, CH4930808”

JOURNAL ARTICLE published 20 July 2018 in Organic Process Research & Development

Authors: Tsuyoshi Haneishi | Yoshiaki Kato | Hiroshi Fukuda | Tomoyuki Shimamura | Takemi Tanokura | Akira Hiraide | Kaichiro Koyama | Masato Fudesaka | Kenji Maeda | Nobuyuki Nakata | Masahiro Nagase | Takahiko Yabuzaki | Hiroaki Takao | Masaharu Kigawa | Hitoshi Shimizu | Makoto Shimizu

Sharpless Asymmetric Dihydroxylation on an Industrial Scale

JOURNAL ARTICLE published 1 November 1997 in Organic Process Research & Development

Authors: Leif Ahrgren | Lori Sutin

Kirk-Othmer Concise Encyclopedia of Chemical Technology (2 Volumes), 5th ed. Wiley-Interscience : West Sussex, U.K. 2007 . 2711 + xxv pages. £208. ISBN 978-0-470-04748-4 .

JOURNAL ARTICLE published November 2007 in Organic Process Research & Development

“Help! I Need Somebody”

JOURNAL ARTICLE published 18 November 2011 in Organic Process Research & Development

Authors: Trevor Laird

Is there a Real Case for Cumulative Control of Structurally Related Genotoxic Impurities?

JOURNAL ARTICLE published 16 July 2010 in Organic Process Research & Development

Authors: David P. Elder | James S. Harvey

Issue Editorial Masthead

JOURNAL ARTICLE published 20 April 2018 in Organic Process Research & Development

Process Understanding: For Scale-Up and Manufacture of Active Ingredients

JOURNAL ARTICLE published 20 September 2013 in Organic Process Research & Development

Authors: Jörgen Blixt

Scientific Knowledge

JOURNAL ARTICLE published 20 September 2013 in Organic Process Research & Development

Authors: David Lathbury

Some Items of Interest to Process R&D Chemists and Engineers

JOURNAL ARTICLE published 20 September 2013 in Organic Process Research & Development

Authors: Mark McLaughlin | Robert Ely | Antonio Ramirez | Paul Richardson | Joseck Muhuhi | Andrei Zlota | John Knight

Understanding and Controlling the Formation of an Impurity during the Development of Muraglitazar, a PPAR Dual Agonist

JOURNAL ARTICLE published 15 January 2010 in Organic Process Research & Development

Authors: Qingmei Ye | Yande Huang | Andrew Rusowicz | Venkatapuram A. Palaniswamy | Thomas V. Raglione

Kinetic Model of Ethyl Benzene Oxidation Catalysed by Manganese Salts

JOURNAL ARTICLE published 1 March 2003 in Organic Process Research & Development

Authors: Tatiana V. Bukharkina | Olga S. Grechishkina | Nikolai G. Digurov | Nadezhda V. Krukovskaya

Heterogeneous Pd-Catalyzed Biphenyl Synthesis under Moderate Conditions in a Solid−Liquid Two-Phase System

JOURNAL ARTICLE published 1 May 2002 in Organic Process Research & Development

Authors: Sudip Mukhopadhyay | Stanislav Ratner | Aviram Spernat | Nida Qafisheh | Yoel Sasson

Oxidative and Reductive Cross-Coupling Reactions Catalyzed by an Anionic “Ligandless” Palladium Complex

JOURNAL ARTICLE published 21 December 2018 in Organic Process Research & Development

Authors: Felix Schroeter | Swantje Lerch | Thomas Strassner