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A pathway-based mutation signature to predict the clinical outcomes and response to CTLA-4 inhibitors in melanoma JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal Research funded by National Natural Science Foundation of China (62072145) | Natural Science Foundation of Heilongjiang Province (LH2019C042) |
A guide to multi-omics data collection and integration for translational medicine JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal |
THE ALBUMIN-BINDING DOMAIN AS A SCAFFOLD FOR PROTEIN ENGINEERING JOURNAL ARTICLE published March 2013 in Computational and Structural Biotechnology Journal |
A Review of Matched-pairs Feature Selection Methods for Gene Expression Data Analysis JOURNAL ARTICLE published 2018 in Computational and Structural Biotechnology Journal Research funded by National Natural Science Foundation of China (61472159,61572227) | International Cooperation and Exchanges NSFC (81320108025) | Development Project of Jilin Province of China (20160204022GX,2017C033,20180414012GH) | National Science Foundation/EPSCoR (IIA-1355423) | National Science Foundation (ACI-1548562) |
HDAC2 as a target for developing anti-cancer drugs JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal Research funded by Ministry of Health and Welfare (HI20C0344) |
A novel P38α MAPK activator Bruceine A exhibits potent anti-pancreatic cancer activity JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal |
Impact of crosslink heterogeneity on extracellular matrix mechanics and remodeling JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal |
Predicting the impacts of mutations on protein-ligand binding affinity based on molecular dynamics simulations and machine learning methods JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal Research funded by Hong Kong Research Grants Council (11200818) | City University of Hong Kong (9610034,9610460) | Shenzhen Fundamental Research Program (JCYJ20170817095210760) | National Natural Science Foundation of China (61602309) | Guangdong Basic and Applied Basic Research Foundation (2019A1515011384) | Interdisciplinary Research Scheme of the Dean’s Research Fund (FLASS/DRF/IDS-3) | Departmental Collaborative Research Fund (MIT/DCRF-R2/18-19) |
Advances in multi-omics study of biomarkers of glycolipid metabolism disorder JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal |
From sequence to function through structure: Deep learning for protein design JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal |
UPIMAPI, reCOGnizer and KEGGCharter: Bioinformatics tools for functional annotation and visualization of (meta)-omics datasets JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal |
A review on automatic analysis techniques for color fundus photographs JOURNAL ARTICLE published 2016 in Computational and Structural Biotechnology Journal |
Multi-omics landscape and clinical significance of a SMAD4-driven immune signature: Implications for risk stratification and frontline therapies in pancreatic cancer JOURNAL ARTICLE published 2022 in Computational and Structural Biotechnology Journal Research funded by National Natural Science Foundation of China (81870457,82172944) |
Predicting host dependency factors of pathogens in Drosophila melanogaster using machine learning JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal Research funded by Deutsche Forschungsgemeinschaft (KO 3678/5-1) | Bundesministerium für Bildung und Forschung (01EO1502) |
p-Nitrophenyl esters provide new insights and applications for the thiolase enzyme OleA JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal |
Amino acid residue at the 165th position tunes EYFP chromophore maturation. A structure-based design JOURNAL ARTICLE published 2021 in Computational and Structural Biotechnology Journal |
Computational saturation mutagenesis to predict structural consequences of systematic mutations in the beta subunit of RNA polymerase in Mycobacterium leprae JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal |
Both intra and inter-domain interactions define the intrinsic dynamics and allosteric mechanism in DNMT1s JOURNAL ARTICLE published 2020 in Computational and Structural Biotechnology Journal Research funded by Jiangsu Planned Projects for Postdoctoral Research Funds (1601168C) | National Natural Science Foundation of China (31872723) | China Postdoctoral Science Foundation (2016M590495) |
Cross-kingdom analyses of transmembrane protein kinases show their functional diversity and distinct origins in protists JOURNAL ARTICLE published 2023 in Computational and Structural Biotechnology Journal |
Structure and function of nucleotide sugar transporters: Current progress JOURNAL ARTICLE published June 2014 in Computational and Structural Biotechnology Journal |