A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα

JOURNAL ARTICLE published 2024 in Chemical Science

Research funded by Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (200021_204602,310030_189065,CRSII5_186230) | H2020 European Research Council (ExploDProteins,866345) | Krebsliga Schweiz (KFS-5442-08-2021)

Authors: Werner Theodor Jauslin | Matthias Schild | Thorsten Schaefer | Chiara Borsari | Clara Orbegozo | Lukas Bissegger | Saule Zhanybekova | Danilo Ritz | Alexander Schmidt | Matthias Wymann | Dennis Gillingham

Ammonia decomposition catalysis using non-stoichiometric lithium imide

JOURNAL ARTICLE published 2015 in Chemical Science

Research funded by Science and Technology Facilities Council (POCF1213-14)

Authors: Joshua W. Makepeace | Thomas J. Wood | Hazel M. A. Hunter | Martin O. Jones | William I. F. David

Observation of the single-ion magnet behavior of d⁸ ions on two-coordinate Co(i)–NHC complexes

JOURNAL ARTICLE published 2015 in Chemical Science

Research funded by National Natural Science Foundation of China (21222208, 21321001, 91422302, 21421091 and 2143200) | Natural Science Foundation of Jiangsu Province (BK20151542)

Authors: Yin-Shan Meng | Zhenbo Mo | Bing-Wu Wang | Yi-Quan Zhang | Liang Deng | Song Gao

Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation

JOURNAL ARTICLE published 2019 in Chemical Science

Research funded by Imperial College London (Junior Research Fellowship) | Cancer Research UK (C309/A11566) | Leverhulme Trust (RPG-2015-345) | Biotechnology and Biological Sciences Research Council (BB/M021149/1,BB/G00954X/1)

Authors: James A. H. Gilburt | Paul Girvan | Julian Blagg | Liming Ying | Charlotte A. Dodson

Ultra-high molecular weight linear coordination polymers with terpyridine ligands

JOURNAL ARTICLE published 2019 in Chemical Science

Authors: Reece W. Lewis | Nino Malic | Kei Saito | Richard A. Evans | Neil R. Cameron

Quantification of photoinduced bending of dynamic molecular crystals: from macroscopic strain to kinetic constants and activation energies

JOURNAL ARTICLE published 2018 in Chemical Science

Research funded by Russian Academy of Sciences (0301-2016-0014,0301-2016-0020)

Authors: Stanislav Chizhik | Anatoly Sidelnikov | Boris Zakharov | Panče Naumov | Elena Boldyreva

Thermochemical functionalisation of graphenes with minimal framework damage

JOURNAL ARTICLE published 2017 in Chem. Sci.

Research funded by National Institute of Environmental Health Sciences (U19ES019536) | Engineering and Physical Sciences Research Council (EP/G007314/1,EP/M506679/1) | European Commission (FP7 604093)

Authors: Sheng Hu | Zachary P. L. Laker | Hannah S. Leese | Noelia Rubio | Martina De Marco | Heather Au | Mark S. Skilbeck | Neil R. Wilson | Milo S. P. Shaffer

Chiral cis-iron(ii) complexes with metal- and ligand-centered chirality for highly regio- and enantioselective alkylation of N-heteroaromatics

JOURNAL ARTICLE published 2020 in Chemical Science

Research funded by National Natural Science Foundation of China (91856203)

Authors: Jinhu Wei | Bei Cao | Chun-Wai Tse | Xiao-Yong Chang | Cong-Ying Zhou | Chi-Ming Che

Harnessing α-l-fucosidase for in vivo cellular senescence imaging

JOURNAL ARTICLE published 2021 in Chemical Science

Research funded by National Research Foundation of Korea (2018R1A3B1052702,2019R1A6A1A10073079,2020H1D3A1A02080172,2020R1A6A3A01100551,2020R1A6A3A01100558,2019M3E5D1A01068998) | Welch Foundation (F-0018) | Department of Biotechnology, Ministry of Science and Technology, India (BT/RLF/Re-entry/59/2018)

Authors: Seyoung Koo | Miae Won | Hao Li | Won Young Kim | Mingle Li | Chenxu Yan | Amit Sharma | Zhiqian Guo | Wei-Hong Zhu | Jonathan L. Sessler | Jin Yong Lee | Jong Seung Kim

The effect of iron binding on uranyl(v) stability

JOURNAL ARTICLE published 2018 in Chemical Science

Research funded by Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (CR23I2_16645)

Authors: Radmila Faizova | Sarah White | Rosario Scopelliti | Marinella Mazzanti

First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated β-galactosidase

JOURNAL ARTICLE published 2020 in Chemical Science

Research funded by National Key Research and Development Program of China (2017YFB0202600) | National Natural Science Foundation of China (81872747,21977082,81903457,81872742) | State Key Laboratory of Bioreactor Engineering (2060204,2018OPEN12) | China Postdoctoral Science Foundation (2018M641946)

Authors: Xiaokang Li | Wenjing Qiu | Jinwen Li | Xi Chen | Yulu Hu | Ying Gao | Donglei Shi | Xinming Li | Huiling Lin | Zelan Hu | Guoqiang Dong | Chunquan Sheng | Bei Jiang | Conglong Xia | Chu-Young Kim | Yuan Guo | Jian Li

A rationally designed rhodamine-based fluorescent probe for molecular imaging of peroxynitrite in live cells and tissues

JOURNAL ARTICLE published 2016 in Chemical Science

Research funded by University of Hong Kong (201309176245,776512M,777611M,HKU 706410) | National Natural Science Foundation of China (31270902)

Authors: Tao Peng | Xingmiao Chen | Lei Gao | Ting Zhang | Wei Wang | Jiangang Shen | Dan Yang

Synthesis and characterization of carbene derivatives of Th@C_3v(8)-C₈₂ and U@C_2v(9)-C₈₂: exceptional chemical properties induced by strong actinide–carbon cage interaction

JOURNAL ARTICLE published 2021 in Chemical Science

Research funded by Natural Science Foundation of Hebei Province (B2019202210) | Natural Science Foundation of Jiangsu Province (BK20200041) | National Natural Science Foundation of China (51302178,91961109)

Authors: Xinye Liu | Bo Li | Wei Yang | Yang-Rong Yao | Le Yang | Jiaxin Zhuang | Xiaomeng Li | Peng Jin | Ning Chen

Carbon nanodots revised: the thermal citric acid/urea reaction

JOURNAL ARTICLE published 2020 in Chemical Science

Research funded by Bundesministerium für Bildung und Forschung (03XP0265)

Authors: Volker Strauss | Huize Wang | Simon Delacroix | Marc Ledendecker | Pablo Wessig

Self-assembly of nucleic acid molecular aggregates catalyzed by a triple-helix probe for miRNA detection and single cell imaging

JOURNAL ARTICLE published 2016 in Chemical Science

Research funded by National Science Foundation of China (21535002,21227008,21405071,21275086) | Linyi University (LYDX2015BS013)

Authors: Zhen Zhang | Yuanyuan Wang | Ningbo Zhang | Shusheng Zhang

Imaging drug uptake by bioorthogonal stimulated Raman scattering microscopy

JOURNAL ARTICLE published 2017 in Chemical Science

Research funded by European Research Council (Advanced Investigator Grant 294440) | Biotechnology and Biological Sciences Research Council (BB/N021614/1) | Cancer Research UK (C10195/A18075,C157/A12753,C157/A15703)

Authors: William J. Tipping | Martin Lee | Alan Serrels | Valerie G. Brunton | Alison N. Hulme

(C₅H_6.16N₂Cl_0.84)(IO₂Cl₂): a birefringent crystal featuring unprecedented (IO₂Cl₂)⁻ anions and π-conjugated organic cations

JOURNAL ARTICLE published 2023 in Chemical Science

Research funded by National Natural Science Foundation of China (21921001,21975256,22031009,22375201)

Authors: Qian-Qian Chen | Chun-Li Hu | Ming-Zhi Zhang | Jiang-Gao Mao

A NIR dye with high-performance n-type semiconducting properties

JOURNAL ARTICLE published 2016 in Chemical Science

Research funded by National Natural Science Foundation of China (21174004,21222403,51473003)

Authors: Jiajun Xie | Ke Shi | Kang Cai | Di Zhang | Jie-Yu Wang | Jian Pei | Dahui Zhao

Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers

JOURNAL ARTICLE published 2017 in Chemical Science

Research funded by Wellcome Trust (015615/Z/14/Z) | National Institutes of Health (GM078114) | Biotechnology and Biological Sciences Research Council (BB/E012558/1,BB/I015361/1) | European Research Council (322408)

Authors: Lydia M. Young | Ling-Hsien Tu | Daniel P. Raleigh | Alison E. Ashcroft | Sheena E. Radford

Streamlining the interface between electronics and neural systems for bidirectional electrochemical communication

JOURNAL ARTICLE published 2023 in Chemical Science

Research funded by National Research Foundation of Korea (2021R1A5A1030054,2022R1A2C3004327)

Authors: Wonkyung Cho | Sun-heui Yoon | Taek Dong Chung